-
Colorimetric quantification of vancomycin by highly active nitroxyl radical compounds
Peer-reviewed
Kyoko Sugiyama, Fumiya Sato, Kentaro Yoshida, Sachiko Komatsu, Tetsuya Ono, Yusuke Sasano, Yoshiharu Iwabuchi, Tsutomu Fujimura, Yoshitomo Kashiwagi, Katsuhiko Sato
Analytical Sciences 41 (2) 179-183 2024/11/19
DOI：
10.1007/s44211-024-00686-5
ISSN：
0910-6340
eISSN：
1348-2246
-
Strategy for C−H Functionalization of Cubanes: From Stoichiometric Reaction to Catalytic Methodology
Peer-reviewed
Masaki Hosaka, Shota Nagasawa, Yoshiharu Iwabuchi
European Journal of Organic Chemistry 27 (46) 2024/11/09
DOI：
10.1002/ejoc.202401055
ISSN：
1434-193X
eISSN：
1099-0690
-
Oxoammonium salts exert antiviral effects against coronavirus via denaturation of their spike proteins
Peer-reviewed
Ryosuke Segawa, Yusuke Sasano, Yusuke Hatakawa, Yuto Fujisawa, Shuhei Akutsu, Masanobu Uchimura, Ami Ikura, Kota Matsumoto, Kazuki Sone, Tomoyuki Oe, Yoshiharu Iwabuchi, Masashi Ito, Noriyasu Hirasawa
Scientific Reports 14 (1) 2024/10/13
Publisher:
Springer Science and Business Media LLC
DOI：
10.1038/s41598-024-75097-7
eISSN：
2045-2322
-
Recent Progress in Accessing Multi-functionalized Caged Hydrocarbons: En Route to Highly Functionalized Saturated (Bio)isosteres of Benzene Rings
Peer-reviewed
Shota Nagasawa, Yoshiharu Iwabuchi
Synthesis 57 (06) 1153-1170 2024/07/04
DOI：
10.1055/a-2360-8218
ISSN：
0039-7881
eISSN：
1437-210X
-
Controlled Aerobic Oxidative Dimerization of Hydroxystilbenoids by Chromium Catalysis
Peer-reviewed
Shota Nagasawa, Yudai Itagaki, Yusuke Sasano, Yoshiharu Iwabuchi
Organic Letters 26 (20) 4178-4182 2024/05/10
DOI：
10.1021/acs.orglett.4c00839
ISSN：
1523-7060
eISSN：
1523-7052
-
PurA is the main target of aurodox, a type III secretion system inhibitor
Peer-reviewed
Yoshihiro Watanabe, Takeshi Haneda, Aoi Kimishima, Asaomi Kuwae, Takuya Suga, Takahiro Suzuki, Yoshiharu Iwabuchi, Masako Honsho, Sota Honma, Masato Iwatsuki, Hidehito Matsui, Hideaki Hanaki, Naoki Kanoh, Akio Abe, Yukihiro Asami, Satoshi Ōmura
Proceedings of the National Academy of Sciences 121 (17) 2024/04/19
Publisher:
Proceedings of the National Academy of Sciences
DOI：
10.1073/pnas.2322363121
ISSN：
0027-8424
eISSN：
1091-6490
-
Electrochemical Characterization of a Novel Organoelectrocatalyst, 7-Azabicyclo[2.2.1]heptan-7-ol (ABHOL), and Its Application to Electrochemical Sensors
Peer-reviewed
Masaki Toda, Kyoko Sugiyama, Fumiya Sato, Yusuke Sasano, Tsutomu Fujimura, Yoshiharu Iwabuchi, Katsuhiko Sato
Chemical and Pharmaceutical Bulletin 72 (3) 249-252 2024/03/01
Publisher:
Pharmaceutical Society of Japan
DOI：
10.1248/cpb.c23-00710
ISSN：
0009-2363
eISSN：
1347-5223
-
Design, Synthesis, and Biological Evaluation of Water-Soluble Prodrugs of C5-Curcuminoid GO-Y030 Based on Reversible Thia-Michael Reaction
Peer-reviewed
Hiroyuki Yamakoshi, Michihiro Fukuda, Hiro Ikeda, Shogo Fujiki, Aki Kohyama, Shota Nagasawa, Hanae Shinozaki, Hiroyuki Shibata, Yoshiharu Iwabuchi
Chemical and Pharmaceutical Bulletin 72 (1) 127-134 2024/01/30
Publisher:
Pharmaceutical Society of Japan
DOI：
10.1248/cpb.c23-00775
ISSN：
0009-2363
eISSN：
1347-5223
-
C–H Alkylation of Cubanes via Catalytic Generation of Cubyl Radicals
Peer-reviewed
Masaki Hosaka, Shota Nagasawa, Yoshiharu Iwabuchi
Organic Letters 26 (3) 658-663 2024/01/18
DOI：
10.1021/acs.orglett.3c04019
ISSN：
1523-7060
eISSN：
1523-7052
-
Biological Evaluation of Isosteric Applicability of 1,3‐Substituted Cuneanes as m‐Substituted Benzenes Enabled by Selective Isomerization of 1,4‐Substituted Cubanes
Peer-reviewed
Kan Fujiwara, Shota Nagasawa, Ryusei Maeyama, Ryosuke Segawa, Noriyasu Hirasawa, Takatsugu Hirokawa, Yoshiharu Iwabuchi
Chemistry – A European Journal 30 (11) 2024/01/11
Publisher:
Wiley
DOI：
10.1002/chem.202303548
ISSN：
0947-6539
eISSN：
1521-3765
-
Development of a fluorous trapping reagent for rapid detection of electrophilic reactive metabolites
Peer-reviewed
Yusuke Akagi, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi
Analytical Methods 16 (24) 3810-3814 2024
DOI：
10.1039/d4ay00577e
ISSN：
1759-9660
eISSN：
1759-9679
-
New Dihydropyridine Derivative Attenuates NF-κB Activation via Suppression of Calcium Influx in a Mouse BV-2 Microglial Cell Line
Peer-reviewed
Kota Sato, Yuto Sasaki, Michiko Ohno-Oishi, Kuniyuki Kano, Junken Aoki, Kosuke Ohsawa, Takayuki Doi, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Chihiro Kawano, Yoshiyuki Hirata, Toru Nakazawa
The Tohoku Journal of Experimental Medicine 2024
Publisher:
Tohoku University Medical Press
DOI：
10.1620/tjem.2024.j024
ISSN：
0040-8727
eISSN：
1349-3329
-
Comprehensive Structural and Electronic Properties of 2-Azaadamantane N-Oxyl Derivatives Correlated with Their Catalytic Ability
Peer-reviewed
Yoshiharu Iwabuchi
ACS Omega 8 49067-49072 2023/12/26
DOI：
10.1021/ACSOMEGA.3C06902
-
Azetidine synthesis by La(OTf)3-catalyzed intramolecular regioselective aminolysis of cis-3,4-epoxy amines
Peer-reviewed
Yuse Kuriyama, Yusuke Sasano, Yoshiharu Iwabuchi
Frontiers in Chemistry 11 2023/09/19
Publisher:
Frontiers Media SA
DOI：
10.3389/fchem.2023.1251299
eISSN：
2296-2646
-
Determination of antibiotics by amperometry using nortropine N-oxyl, a highly active nitroxyl radical
Peer-reviewed
Tetsuya Ono, Fumiya Sato, Masayuki Kumano, Sachiko Komatsu, Kyoko Sugiyama, Kazuhiro Watanabe, Kentaro Yoshida, Yusuke Sasano, Tsutomu Fujimura, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Katsuhiko Sato
Analytical Sciences 39 (10) 1771-1775 2023/06/28
Publisher:
Springer Science and Business Media LLC
DOI：
10.1007/s44211-023-00388-4
ISSN：
0910-6340
eISSN：
1348-2246
-
Asymmetric Total Synthesis of Cytotrienin A: Late‐Stage Installation of C11 Side Chain onto the Macrolactam Scaffold
Peer-reviewed
Yuki Tateishi, Ryo Sato, Shingo Komatsu, Masatsugu Noguchi, Shota Nagasawa, Yusuke Sasano, Naoki Kanoh, Yoshiharu Iwabuchi
Angewandte Chemie International Edition 62 (29) 2023/06/12
Publisher:
Wiley
DOI：
10.1002/anie.202303140
ISSN：
1433-7851
eISSN：
1521-3773
-
That’s why I can’t stop doing research
Yoshiharu Iwabuchi
Journal of Synthetic Organic Chemistry, Japan 81 (6) 626-629 2023/06/01
DOI：
10.5059/yukigoseikyokaishi.81.626
ISSN：
0037-9980
eISSN：
1883-6526
-
Mono-Carbonyl Curcumin Analogs for Cancer Therapy
Peer-reviewed
Takashi MaruYama, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Shibata
Biological and Pharmaceutical Bulletin 46 (6) 756-763 2023/06/01
Publisher:
Pharmaceutical Society of Japan
DOI：
10.1248/bpb.b23-00103
ISSN：
0918-6158
eISSN：
1347-5215
-
4‐Chloro‐2‐azaadamantane N‐Oxyl (4‐Cl‐AZADO): A Readily Preparable Organocatalyst for NOx Co‐catalyzed Aerobic Alcohol Oxidation
Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
Asian Journal of Organic Chemistry 12 (4) 2023/02/17
DOI：
10.1002/ajoc.202300031
ISSN：
2193-5807
eISSN：
2193-5815
-
Identification of the Optimal Framework for Nitroxyl Radical/Hydroxylamine in Copper-Cocatalyzed Aerobic Alcohol Oxidation
Peer-reviewed
Yoshiharu Iwabuchi
The Journal of Organic Chemistry 88 (3) 1434-1444 2023/02/03
DOI：
10.1021/ACS.JOC.2C02327
ISSN：
0022-3263 1520-6904
-
Selective Synthesis of 1,3-Substituted Cuneanes: En Route to Potent Bioisosteres of m-Substituted Benzenes
Yoshiharu Iwabuchi
ChemRxiv 2023
DOI：
10.26434/CHEMRXIV-2023-FGXXM-V2
-
Selective Synthesis of 1,3-Substituted Cuneanes: En Route to Potent Bioisosteres of m-Substituted Benzenes
Yoshiharu Iwabuchi
ChemRxiv 2023
DOI：
10.26434/CHEMRXIV-2023-FGXXM
-
C-H Alkylation of Cubanes via Polar Effect-Assisted Photocatalytic Generation of Cubyl Radicals
Yoshiharu Iwabuchi
ChemRxiv 2023
DOI：
10.26434/CHEMRXIV-2023-S8FKR
-
A Nitrile-Tagged Raman Sensor for the Ratiometric Detection of Thiols in Live Cells
Yoshiharu Iwabuchi
ChemRxiv 2023
DOI：
10.26434/CHEMRXIV-2023-0LKM0
-
EXAMINATION OF THE EFFECTIVENESS OF DIABETIC NEPHROPATHY TREATMENT TARGETING CHREBP ACTIVITY
Yoshiharu Iwabuchi
Journal of Hypertension 2023
-
Ratiometric analysis of reversible thia-Michael reactions using nitrile-tagged molecules by Raman microscopy
Peer-reviewed
Hiroyuki Yamakoshi, Daiki Shibata, Kazuki Bando, Shinji Kajimoto, Aki Kohyama, Syusuke Egoshi, Kosuke Dodo, Yoshiharu Iwabuchi, Mikiko Sodeoka, Katsumasa Fujita, Takakazu Nakabayashi
Chemical Communications 59 (98) 14563-14566 2023
Publisher:
Royal Society of Chemistry (RSC)
DOI：
10.1039/d3cc05015g
ISSN：
1359-7345
eISSN：
1364-548X
-
Sequential click modification of a lithium-ion endohedral fullerene connecting small molecules through a dieneazide linker
Peer-reviewed
Shogo Fujiki, Takumi Takada, Shota Nagasawa, Hiroshi Okada, Yusuke Sasano, Eunsang Kwon, Yutaka Matsuo, Yoshiharu Iwabuchi
Chemical Communications 59 (9) 1237-1240 2023
DOI：
10.1039/d2cc06301h
ISSN：
1359-7345
eISSN：
1364-548X
-
Electrochemical reactions of highly active nitroxyl radicals with thiol compounds
Peer-reviewed
Masayuki Kumano, Kyoko Sugiyama, Fumiya Sato, Sachiko Komatsu, Kazuhiro Watanabe, Tetsuya Ono, Kentaro Yoshida, Yusuke Sasano, Yoshiharu Iwabuchi, Tsutomu Fujimura, Yoshitomo Kashiwagi, Katsuhiko Sato
Analytical Sciences 2022/12/28
DOI：
10.1007/s44211-022-00246-9
ISSN：
0910-6340
eISSN：
1348-2246
-
Enantiocontrolled Access to an Intermediate for Highly Functionalized Clovane-Type Terpenoids: Formal Synthesis of Rumphellclovane E
Peer-reviewed
Daigo Ninomiya, Shota Nagasawa, Yoshiharu Iwabuchi
Organic Letters 24 (41) 7572-7576 2022/10/11
DOI：
10.1021/acs.orglett.2c02960
ISSN：
1523-7060
eISSN：
1523-7052
-
Toward the Creation of Induced Pluripotent Small (iPS) Molecules: Establishment of a Modular Synthetic Strategy for the Heronamide C-type Polyene Macrolactams and Their Conformational and Reactivity Analysis
Peer-reviewed
Naoki Kanoh, Yuta Terajima, Suguru Tanaka, Ryusei Terashima, Hiromichi Nishiyama, Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi, Shinichi Nishimura, Hideaki Kakeya
The Journal of Organic Chemistry 86 (23) 16231-16248 2021/12/03
DOI：
10.1021/acs.joc.1c01760
ISSN：
0022-3263
eISSN：
1520-6904
-
A chalcone derivative suppresses TSLP induction in mice and human keratinocytes through binding to BET family proteins
Peer-reviewed
Ryosuke Segawa, Hiroyuki Takeda, Takeshi Yokoyama, Momoha Ishida, Chihiro Miyata, Taiji Saito, Ryosuke Ishihara, Tomoya Nakagita, Yusuke Sasano, Naoki Kanoh, Yoshiharu Iwabuchi, Mineyuki Mizuguchi, Masahiro Hiratsuka, Noriyasu Hirasawa
Biochemical Pharmacology 194 114819-114819 2021/12
DOI：
10.1016/j.bcp.2021.114819
ISSN：
0006-2952
eISSN：
1873-2968
-
Ortho-C-H Acetoxylation of Cubane Enabling Access to Cubane Analogues of Pharmaceutically Relevant Scaffolds
Peer-reviewed
Shota Nagasawa, Masaki Hosaka, Yoshiharu Iwabuchi
Organic Letters 23 (22) 8717-8721 2021/11/19
DOI：
10.1021/acs.orglett.1c03144
ISSN：
1523-7060
eISSN：
1523-7052
-
Design, Synthesis, and Antifungal Activity of 16,17-Dihydroheronamide C and ent-Heronamide C
Peer-reviewed
Naoki Kanoh, Ryusei Terashima, Hiromichi Nishiyama, Yuta Terajima, Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi, Hiroaki Saito, Syusuke Egoshi, Kosuke Dodo, Mikiko Sodeoka, Chengqian Pan, Yoshinobu Ikeuchi, Shinichi Nishimura, Hideaki Kakeya
The Journal of Organic Chemistry 86 (23) 16249-16258 2021/11/16
DOI：
10.1021/acs.joc.1c01761
ISSN：
0022-3263
eISSN：
1520-6904
-
Nitroxyl Radical/Copper-Catalyzed Electrooxidation of Alcohols and Amines at Low Potentials
Peer-reviewed
Kyoko Sugiyama, Yusuke Sasano, Sachiko Komatsu, Kentaro Yoshida, Tetsuya Ono, Tsutomu Fujimura, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Katsuhiko Sato
Chemical and Pharmaceutical Bulletin 69 (10) 1005-1009 2021/10/01
DOI：
10.1248/cpb.c21-00409
ISSN：
0009-2363
eISSN：
1347-5223
-
The Curcumin Analog GO-Y030 Controls the Generation and Stability of Regulatory T Cells
Peer-reviewed
Takashi MaruYama, Shuhei Kobayashi, Hiroko Nakatsukasa, Yuki Moritoki, Daiki Taguchi, Yoichi Sunagawa, Tatsuya Morimoto, Atsuko Asao, Wenwen Jin, Yuji Owada, Naoto Ishii, Yoshiharu Iwabuchi, Akihiko Yoshimura, WanJun Chen, Hiroyuki Shibata
Frontiers in Immunology 12 2021/06/23
DOI：
10.3389/fimmu.2021.687669
ISSN：
1664-3224
eISSN：
1664-3224
-
Chromium-Salen Complex/Nitroxyl Radical Cooperative Catalysis: A Combination for Aerobic Intramolecular Dearomative Coupling of Phenols
Peer-reviewed
Shota Nagasawa, Shogo Fujiki, Yusuke Sasano, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 86 (9) 6952-6968 2021/05
DOI：
10.1021/acs.joc.1c00438
ISSN：
0022-3263
eISSN：
1520-6904
-
Expansion of Substrate Scope for Nitroxyl Radical/Copper-Catalyzed Aerobic Oxidation of Primary Alcohols: A Guideline for Catalyst Selection
Peer-reviewed
Yusuke Sasano, Aoto Yamaichi, Ryota Sasaki, Shota Nagasawa, Yoshiharu Iwabuchi
CHEMICAL & PHARMACEUTICAL BULLETIN 69 (5) 488-497 2021/05
DOI：
10.1248/cpb.c21-00043
ISSN：
0009-2363
eISSN：
1347-5223
-
Electrochemical Evaluation of Nitroxyl Radical Catalysts and Electrochemical Detection of Cyclosporin A
Peer-reviewed
Sachiko Komatsu, Yusuke Sasano, Kyoko Sugiyama, Kazuhiro Watanabe, Masayuki Kumano, Kentaro Yoshida, Tetsuya Ono, Yoshiharu Iwabuchi, Tsutomu Fujimura, Katsuhiko Sato, Yoshitomo Kashiwagi
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE 16 (2) 1-9 2021/02
DOI：
10.20964/2021.02.30
ISSN：
1452-3981
eISSN：
1452-3981
-
Design, Synthesis and Biological Activity of 16,17-Dihydroheronamide C and ent-Heronamide C
Yoshiharu Iwabuchi
ChemRxiv 2021
DOI：
10.26434/CHEMRXIV-2021-278L6-V2
-
Synthetic Access to gem-Difluoropropargyl Vinyl Ethers and Their Application to Propargyl Claisen Rearrangement
Peer-reviewed
Toshitaka Okamura, Kenta Koyamada, Junichiro Kanazawa, Kazunori Miyamoto, Yoshiharu Iwabuchi, Masanobu Uchiyama, Naoki Kanoh
JOURNAL OF ORGANIC CHEMISTRY 86 (2) 1911-1924 2021/01
DOI：
10.1021/acs.joc.0c01777
ISSN：
0022-3263
eISSN：
1520-6904
-
Catalysis of electro-oxidation of antibiotics by nitroxyl radicals and the electrochemical sensing of vancomycin
Peer-reviewed
Tetsuya Ono, Kyoko Sugiyama, Sachiko Komatsu, Masayuki Kumano, Kentaro Yoshida, Takenori Dairaku, Tsutomu Fujimura, Yusuke Sasano, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi, Katsuhiko Sato
RSC Advances 11 (35) 21622-21628 2021
DOI：
10.1039/d1ra03681e
eISSN：
2046-2069
-
Highly Regioselective 5-endo-tet Cyclization of 3,4-Epoxy Amines into 3-Hydroxypyrrolidines Catalyzed by La(OTf)(3)
Peer-reviewed
Yuse Kuriyama, Yusuke Sasano, Yoshihiko Hoshino, Shun-ichiro Uesugi, Aoto Yamaichi, Yoshiharu Iwabuchi
CHEMISTRY-A EUROPEAN JOURNAL 27 (6) 1961-1965 2021/01
DOI：
10.1002/chem.202004455
ISSN：
0947-6539
eISSN：
1521-3765
-
The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice
Peer-reviewed
Kana Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Hiroki Wakabayashi, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Nurmila Sari, Satoshi Shimizu, Ayumi Katayama, Hiroyuki Shibata, Yoshiharu Iwabuchi, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
SCIENTIFIC REPORTS 10 (1) 2020/04
DOI：
10.1038/s41598-020-64207-w
ISSN：
2045-2322
-
Electrochemical determination of choline using nortropine-N-oxyl for a non-enzymatic system
Peer-reviewed
Yoshitomo Kashiwagi, Tetsuya Ono, Fumiya Sato, Masayuki Kumano, Kentaro Yoshida, Takenori Dairaku, Yusuke Sasano, Yoshiharu Iwabuchi, Katsuhiko Sato
SENSING AND BIO-SENSING RESEARCH 27 2020/02
DOI：
10.1016/j.sbsr.2019.100302
eISSN：
2214-1804
-
Highly Chemoselective gem-Difluoropropargylation of Aliphatic Alcohols
Peer-reviewed
Toshitaka Okamura, Syusuke Egoshi, Kosuke Dodo, Mikiko Sodeoka, Yoshiharu Iwabuchi, Naoki Kanoh
CHEMISTRY-A EUROPEAN JOURNAL 25 (70) 16002-16006 2019/12
DOI：
10.1002/chem.201904366
ISSN：
0947-6539
eISSN：
1521-3765
-
An integrated screening system for the selection of exemplary substrates for natural and engineered cytochrome P450s
Peer-reviewed
Naoki Kanoh, Ayano Kawamata-Asano, Kana Suzuki, Yusuke Takahashi, Takeshi Miyazawa, Takemichi Nakamura, Takashi Moriya, Hiroyuki Hirano, Hiroyuki Osada, Yoshiharu Iwabuchi, Shunji Takahashi
SCIENTIFIC REPORTS 9 (1) 18023 2019/12
DOI：
10.1038/s41598-019-54473-8
ISSN：
2045-2322
-
Methyl-Selective alpha-Oxygenation of Tertiary Amines to Formamides by Employing Copper/Moderately Hindered Nitroxyl Radical (DMN-AZADO or 1-Me-AZADO)
Peer-reviewed
Satoru Nakai, Takafumi Yatabe, Kosuke Suzuki, Yusuke Sasano, Yoshiharu Iwabuchi, Junya Hasegawa, Noritaka Mizuno, Kazuya Yamaguchi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 58 (46) 16651-16659 2019/11
DOI：
10.1002/anie.201909005
ISSN：
1433-7851
eISSN：
1521-3773
-
Gold(I)-catalyzed Nicholas reaction with aromatic molecules utilizing a bifunctional propargyl dicobalt hexacarbonyl complex
Peer-reviewed
Toshitaka Okamura, Shogo Fujiki, Yoshiharu Iwabuchi, Naoki Kanoh
ORGANIC & BIOMOLECULAR CHEMISTRY 17 (37) 8522-8526 2019/10
DOI：
10.1039/c9ob01348b
ISSN：
1477-0520
eISSN：
1477-0539
-
クルクミンをリード化合物としたヒストンアセチル化酵素活性を指標とする新規心不全治療薬の探索
清水 果奈, 船本 雅文, 砂川 陽一, 刀坂 泰史, 宮崎 雄輔, Sari Nurmila, 清水 聡史, 柴田 浩行, 岩渕 好治, 和田 啓道, 長谷川 浩二, 森本 達也
日本抗加齢医学会総会プログラム・抄録集 19回 234-234 2019/06
Publisher:
(一社)日本抗加齢医学会
-
Recent Progress in Oxidative Organic Transformations Employing Nitroxyl Radicals
Peer-reviewed
Yoshiharu Iwabuchi
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 77 (5) 424-432 2019/05
DOI：
10.5059/yukigoseikyokaishi.77.424
ISSN：
0037-9980
-
Ln(OTf)(3)-catalysed highly regioselective alcoholysis of 2,3-epoxy alcohols
Peer-reviewed
Daichi Nakamura, Yusuke Sasano, Yoshiharu Iwabuchi
ORGANIC & BIOMOLECULAR CHEMISTRY 17 (14) 3581-3589 2019/04
DOI：
10.1039/c8ob02448k
ISSN：
1477-0520
eISSN：
1477-0539
-
Electrochemical Detection of Triglycerides Based on an Enzymatic Reaction and Electrocatalytic Oxidation with Nortropine-N-oxyl
Tetsuya Ono, Katsuhiko Sato, Yusuke Sasano, Kentaro Yoshida, Takenori Dairaku, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi
ELECTROANALYSIS 31 (4) 603-606 2019/04
DOI：
10.1002/elan.201800660
ISSN：
1040-0397
eISSN：
1521-4109
-
Safe and Scalable Aerobic Oxidation by 2-Azaadamantan-2-ol (AZADOL)/NOx Catalysis: Large-Scale Preparation of Shi's Catalyst
Yusuke Sasano, Hikaru Sato, Shinsuke Tadokoro, Masami Kozawa, Yoshiharu Iwabuchi
ORGANIC PROCESS RESEARCH & DEVELOPMENT 23 (4) 571-577 2019/04
DOI：
10.1021/acs.oprd.8b00456
ISSN：
1083-6160
eISSN：
1520-586X
-
Green Oxidative Synthesis of Aldehydes and Ketones
Yoshiharu Iwabuchi
Green Oxidation in Organic Synthesis 2019
-
Electrochemical Oxidation of Amines Using a Nitroxyl Radical Catalyst and the Electroanalysis of Lidocaine
Peer-reviewed
Katsuhiko Sato, Tetsuya Ono, Yusuke Sasano, Fumiya Sato, Masayuki Kumano, Kentaro Yoshida, Takenori Dairaku, Yoshiharu Iwabuchi, Yoshitomo Kashiwagi
Catalysts 8 (12) 649-649 2018/12
DOI：
10.3390/catal8120649
ISSN：
2073-4344
eISSN：
2073-4344
-
Dietary intake of pyrolyzed deketene curcumin inhibits gastric carcinogenesis
Peer-reviewed
Taichi Yoshida, Takashi Maruyama, Masatomo Miura, Masahiro Inoue, Koji Fukuda, Kazuhiro Shimazu, Daiki Taguchi, Hiroaki Kanda, Masanobu Oshima, Yoshiharu Iwabuchi, Hiroyuki Shibata
JOURNAL OF FUNCTIONAL FOODS 50 192-200 2018/11
DOI：
10.1016/j.jff.2018.09.033
ISSN：
1756-4646
-
2-Azaadamantane N-oxyl (AZADO)/Cu Catalysis Enables Chemoselective Aerobic Oxidation of Alcohols Containing Electron-Rich Divalent Sulfur Functionalities
Peer-reviewed
Yusuke Sasano, Naoki Kogure, Shota Nagasawa, Koki Kasabata, Yoshiharu Iwabuchi
ORGANIC LETTERS 20 (19) 6104-6107 2018/10
DOI：
10.1021/acs.orglett.8b02528
ISSN：
1523-7060
eISSN：
1523-7052
-
Curcumin analog, GO-Y078, overcomes resistance to tumor angiogenesis inhibitors
Peer-reviewed
Kazuhiro Shimazu, Masahiro Inoue, Shunsuke Sugiyama, Koji Fukuda, Taichi Yoshida, Daiki Taguchi, Yoshihiko Uehara, Sei Kuriyama, Masamitsu Tanaka, Masatomo Miura, Hiroshi Nanjyo, Yoshiharu Iwabuchi, Hiroyuki Shibata
CANCER SCIENCE 109 (10) 3285-3293 2018/08/16
DOI：
10.1111/cas.13741
10.1248/bpb.b23-00103_references_DOI_U3hHv60R4aT4ximOkZqIwU2fmRV
ISSN：
1347-9032
eISSN：
1349-7006
-
CuCl/TMEDA/nor-AZADO-catalyzed aerobic oxidative acylation of amides with alcohols to produce imides
Peer-reviewed
Kengo Kataoka, Keiju Wachi, Xiongjie Jin, Kosuke Suzuki, Yusuke Sasano, Yoshiharu Iwabuchi, Jun-ya Hasegawa, Noritaka Mizuno, Kazuya Yamaguchi
CHEMICAL SCIENCE 9 (21) 4756-4768 2018/06
DOI：
10.1039/c8sc01410h
ISSN：
2041-6520
eISSN：
2041-6539
-
Expedient Entry to 1-Aminoadamantane Derivatives via Aza-Prins Cyclization of 7-Methylenebicyclo[3.3.1]nonan-3-one Oximes
Peer-reviewed
Tetsuya Kuga, Yusuke Sasano, Masaki Tomizawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
SYNTHESIS-STUTTGART 50 (9) 1820-1826 2018/05
DOI：
10.1055/s-0036-1591920
ISSN：
0039-7881
eISSN：
1437-210X
-
Stereocontrolled Construction of ABCD Tetracyclic Ring System with Vicinal All-Carbon Quaternary Stereogenic Centers of Calyciphylline A Type Alkaloids
Peer-reviewed
Yusuke Sasano, Junpei Koyama, Kaori Yoshikawa, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
ORGANIC LETTERS 20 (10) 3053-3056 2018/05
DOI：
10.1021/acs.orglett.8b01087
ISSN：
1523-7060
eISSN：
1523-7052
-
IBX as a catalyst for dehydration of hydroperoxides: green entry to alpha,beta-unsaturated ketones via oxygenative allylic transposition
Peer-reviewed
Tetsuya Kuga, Yusuke Sasano, Yoshiharu Iwabuchi
CHEMICAL COMMUNICATIONS 54 (7) 798-801 2018/01
DOI：
10.1039/c7cc08957k
ISSN：
1359-7345
eISSN：
1364-548X
-
Synthetic Analogs of Curcumin as Modulators of Multidrug Resistance-Linked ABC Transporters
Peer-reviewed
Megumi Murakami, Shinobu Ohnuma, Katsuyoshi Kudoh, Masaharu Ishida, Yoshiharu Iwabuchi, Hiroyuki Shibata, Hiroki Hayashi, Fuyuhiko Motoi, Takeshi Naitoh, Michiaki Unno
CANCER SCIENCE 109 63-63 2018/01
ISSN：
1349-7006
-
Synthetic Analogs of Curcumin Modulate the Function of Multidrug Resistance-Linked ATP-Binding Cassette Transporter ABCG2
Peer-reviewed
Megumi Murakami, Shinobu Ohnuma, Michihiro Fukuda, Eduardo E. Chufan, Katsuyoshi Kudoh, Keigo Kanehara, Norihiko Sugisawa, Masaharu Ishida, Takeshi Naitoh, Hiroyuki Shibata, Yoshiharu Iwabuchi, Suresh V. Ambudkar, Michiaki Unno
DRUG METABOLISM AND DISPOSITION 45 (11) 1166-1177 2017/11
DOI：
10.1124/dmd.117.076000
ISSN：
0090-9556
eISSN：
1521-009X
-
Substrate Recognition by a Dual-Function P450 Monooxygenase GfsF Involved in FD-891 Biosynthesis
Peer-reviewed
Akimasa Miyanaga, Ryuichi Takayanagi, Takashi Furuya, Ayano Kawamata, Tomohiro Itagaki, Yoshiharu Iwabuchi, Naoki Kanoh, Fumitaka Kudo, Tadashi Eguchi
CHEMBIOCHEM 18 (21) 2179-2187 2017/11
DOI：
10.1002/cbic.201700429
ISSN：
1439-4227
eISSN：
1439-7633
-
Nazarov Cyclization Entry to Chiral Bicyclo[5.3.0]decanoid Building Blocks and Its Application to Formal Synthesis of (-)-Englerin A
Peer-reviewed
Keisuke Morisaki, Yusuke Sasano, Takahiro Koseki, Takuro Shibuta, Naoki Kanoh, Wen-Hua Chiou, Yoshiharu Iwabuchi
ORGANIC LETTERS 19 (19) 5142-5145 2017/10
DOI：
10.1021/acs.orglett.7b02428
ISSN：
1523-7060
eISSN：
1523-7052
-
A mild two-step propargylation of aromatic bioactive small molecules
Naoki Kanoh, Toshitaka Okamura, Takahiro Suzuki, Yoshiharu Iwabuchi
ORGANIC & BIOMOLECULAR CHEMISTRY 15 (34) 7190-7195 2017/09
DOI：
10.1039/c7ob01587a
ISSN：
1477-0520
eISSN：
1477-0539
-
Catalytic Oxygenative Allylic Transposition of Alkenes into Enones with an Azaadamantane-Type Oxoammonium Salt Catalyst
Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
CHEMISTRY-A EUROPEAN JOURNAL 23 (43) 10276-10279 2017/08
DOI：
10.1002/chem.201702512
ISSN：
0947-6539
eISSN：
1521-3765
-
Synthetic analogs of curcumin as modulators of multidrug resistance-linked ABC transporters
Peer-reviewed
Megumi Obara, Shinobu Ohnuma, Eduardo E. Chufan, Masaharu Ishida, Katsuyoshi Kudoh, Norihiko Sugisawa, Hideo Ohtsuka, Takeshi Naitoh, Hiroyuki Shibata, Yoshiharu Iwabuchi, Suresh V. Ambudkar, Michiaki Unno
CANCER RESEARCH 77 2017/07
DOI：
10.1158/1538-7445.AM2017-3242
ISSN：
0008-5472
eISSN：
1538-7445
-
Concise, Protecting-Group-Free Synthesis of (+)-Nemonapride via Eu(OTf)(3)-Catalyzed Aminolysis of 3,4-Epoxy Alcohol
Peer-reviewed
Shun-ichiro Uesugi, Yusuke Sasano, Shogo Matsui, Naoki Kanoh, Yoshiharu Iwabuchi
CHEMICAL & PHARMACEUTICAL BULLETIN 65 (1) 22-24 2017/01
DOI：
10.1248/cpb.c16-00568
ISSN：
0009-2363
-
Synthesis of 1,3-Cycloalkadienes from Cycloalkenes: Unprecedented Reactivity of Oxoammonium Salts
Peer-reviewed
Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
SYNLETT 28 (1) A13-A16 2017/01
ISSN：
0936-5214
eISSN：
1437-2096
-
Design and synthesis of the penta(acetoxymethyl) ester of dioctanoyl phosphatidylinositol-3,5-bisphosphate
Peer-reviewed
Naoki Kanoh, Kosuke Mano, Daisuke Saigusa, Takeo Usui, Yoshiharu Iwabuchi
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 26 (23) 5770-5772 2016/12
DOI：
10.1016/j.bmcl.2016.10.046
ISSN：
0960-894X
eISSN：
1464-3405
-
Synthesis of 1,3-Cycloalkadienes from Cycloalkenes: Unprecedented Reactivity of Oxoammonium Salts
Peer-reviewed
Shota Nagasawa, Yusuke Sasano, Yoshiharu Iwabuchi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 55 (42) 13189-13194 2016/10
DOI：
10.1002/anie.201607752
ISSN：
1433-7851
eISSN：
1521-3773
-
Asymmetric Total Synthesis of Heronamides A-C: Stereochemical Confirmation and Impact of Long-Range Stereochemical Communication on the Biological Activity
Peer-reviewed
Naoki Kanoh, Shunya Itoh, Kohei Fujita, Kohei Sakanishi, Ryosuke Sugiyama, Yuta Terajima, Yoshiharu Iwabuchi, Shinichi Nishimura, Hideaki Kakeya
CHEMISTRY-A EUROPEAN JOURNAL 22 (25) 8586-8595 2016/06
DOI：
10.1002/chem.201600569
ISSN：
0947-6539
eISSN：
1521-3765
-
Identification of anti-cancer chemical compounds using Xenopus embryos
Peer-reviewed
Masamitsu Tanaka, Sei Kuriyama, Go Itoh, Aki Kohyama, Yoshiharu Iwabuchi, Hiroyuki Shibata, Masakazu Yashiro, Namiko Aiba
CANCER SCIENCE 107 (6) 803-811 2016/06
DOI：
10.1111/cas.12940
ISSN：
1347-9032
eISSN：
1349-7006
-
Vicenistatin induces early endosome-derived vacuole formation in mammalian cells
Peer-reviewed
Yuko Nishiyama, Tomohiro Ohmichi, Sayaka Kazami, Hiroki Iwasaki, Kousuke Mano, Yoko Nagumo, Fumitaka Kudo, Sosaku Ichikawa, Yoshiharu Iwabuchi, Naoki Kanoh, Tadashi Eguchi, Hiroyuki Osada, Takeo Usui
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 80 (5) 902-910 2016/05
DOI：
10.1080/09168451.2015.1132152
ISSN：
0916-8451
eISSN：
1347-6947
-
Synthesis and structure-activity relationship study of FD-891: importance of the side chain and C8-C9 epoxide for cytotoxic activity against cancer cells
Peer-reviewed
Tomohiro Itagaki, Ayano Kawamata, Miho Takeuchi, Keisuke Hamada, Yoshiharu Iwabuchi, Tadashi Eguchi, Fumitaka Kudo, Takeo Usui, Naoki Kanoh
JOURNAL OF ANTIBIOTICS 69 (4) 287-293 2016/04
DOI：
10.1038/ja.2015.148
ISSN：
0021-8820
-
がん細胞遊走阻害活性天然物fusarisetin Aの合成研究
高山 亜紀, 叶 直樹, 岩渕 好治
日本薬学会年会要旨集 136年会 (2) 83-83 2016/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
An enantiocontrolled entry to the tricyclic polar segment of (+)-fusarisetin A
Peer-reviewed
Aki Kohyama, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
TETRAHEDRON LETTERS 57 (5) 517-519 2016/02
DOI：
10.1016/j.tetlet.2015.12.049
ISSN：
0040-4039
-
Total Synthesis of the Proposed Structure of Turkiyenine
Peer-reviewed
Hisataka Kobayashi, Yusuke Sasano, Naoki Kanoh, Eunsang Kwon, Yoshiharu Iwabuchi
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2016 (2) 270-273 2016/01
DOI：
10.1002/ejoc.201501365
ISSN：
1434-193X
eISSN：
1099-0690
-
A Curcumin Analog, GO-Y078, Effectively Inhibits Angiogenesis through Actin Disorganization
Peer-reviewed
Shunsuke Sugiyama, Yuki Yoshino, Sei Kuriyama, Masahiro Inoue, Keigo Komine, Kazunori Otsuka, Aki Kohyama, Hiroyuki Yamakoshi, Chikashi Ishioka, Masamitsu Tanaka, Yoshiharu Iwabuchi, Hiroyuki Shibata
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 16 (5) 633-647 2016
DOI：
10.2174/1871520615666151013125559
ISSN：
1871-5206
eISSN：
1875-5992
-
A diarylpentanoid curcumin analog exhibits improved radioprotective potential in the intestinal mucosa
Peer-reviewed
Koji Fukuda, Yoshihiko Uehara, Eiko Nakata, Masahiro Inoue, Kazuhiro Shimazu, Taichi Yoshida, Hiroaki Kanda, Hiroshi Nanjo, Yoshio Hosoi, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Shibata
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 92 (7) 388-394 2016
DOI：
10.3109/09553002.2016.1164910
ISSN：
0955-3002
eISSN：
1362-3095
-
Reversibility of the thia-Michael reaction of cytotoxic C-5-curcuminoid and structure-activity relationship of bis-thiol-adducts thereof
Peer-reviewed
Aki Kohyama, Michihiro Fukuda, Shunsuke Sugiyama, Hiroyuki Yamakoshi, Naoki Kanoh, Chikashi Ishioka, Hiroyuki Shibatac, Yoshiharu Iwabuchi
ORGANIC & BIOMOLECULAR CHEMISTRY 14 (45) 10683-10687 2016
DOI：
10.1039/c6ob01771a
ISSN：
1477-0520
eISSN：
1477-0539
-
Total Synthesis and Biological Evaluation of Irciniastatin A (a.k.a. Psymberin) and Irciniastatin B
Peer-reviewed
Shun-ichiro Uesugi, Tsubasa Watanabe, Takamichi Imaizumi, Yu Ota, Keisuke Yoshida, Haruna Ebisu, Takumi Chinen, Yoko Nagumo, Masatoshi Shibuya, Naoki Kanoh, Takeo Usui, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 80 (24) 12333-12350 2015/12
DOI：
10.1021/acs.joc.5b02256
ISSN：
0022-3263
eISSN：
1520-6904
-
Inhibition of beta-catenin and STAT3 with a curcumin analog suppresses gastric carcinogenesis in vivo
Peer-reviewed
Yoshihiko Uehara, Masahiro Inoue, Koji Fukuda, Hiroyuki Yamakoshi, Yoshio Hosoi, Hiroaki Kanda, Masanobu Oshima, Yoshiharu Iwabuchi, Hiroyuki Shibata
GASTRIC CANCER 18 (4) 774-783 2015/10
DOI：
10.1007/s10120-014-0434-3
ISSN：
1436-3291
eISSN：
1436-3305
-
Structure-Activity Relationships of the Antitumor C-5-Curcuminoid GO-Y030
Peer-reviewed
Aki Kohyama, Hiroyuki Yamakoshi, Shoko Hongo, Naoki Kanoh, Hiroyuki Shibata, Yoshiharu Iwabuchi
MOLECULES 20 (8) 15374-15391 2015/08
DOI：
10.3390/molecules200815374
ISSN：
1420-3049
-
Irciniastatin A Induces Potent and Sustained Activation of Extracellular Signal-Regulated Kinase and Thereby Promotes Ectodomain Shedding of Tumor Necrosis Factor Receptor 1 in Human Lung Carcinoma A549 Cells
Peer-reviewed
Hue Tu Quach, Seiya Hirano, Sayuri Fukuhara, Tsubasa Watanabe, Naoki Kanoh, Yoshiharu Iwabuchi, Takeo Usui, Takao Kataoka
BIOLOGICAL & PHARMACEUTICAL BULLETIN 38 (6) 941-946 2015/06
DOI：
10.1248/bpb.b15-00078
ISSN：
0918-6158
-
Irciniastatin A, a pederin-type translation inhibitor, promotes ectodomain shedding of cell-surface tumor necrosis factor receptor 1
Peer-reviewed
Seiya Hirano, Hue Tu Quach, Tsubasa Watanabe, Naoki Kanoh, Yoshiharu Iwabuchi, Takeo Usui, Takao Kataoka
JOURNAL OF ANTIBIOTICS 68 (6) 417-420 2015/06
DOI：
10.1038/ja.2015.3
ISSN：
0021-8820
-
Highly Efficient Aerobic Oxidation of Alcohols by Using Less-Hindered Nitroxyl-Radical/Copper Catalysis: Optimum Catalyst Combinations and Their Substrate Scope
Peer-reviewed
Yusuke Sasano, Naoki Kogure, Tomohiro Nishiyama, Shota Nagasawa, Yoshiharu Iwabuchi
CHEMISTRY-AN ASIAN JOURNAL 10 (4) 1004-1009 2015/04
DOI：
10.1002/asia.201403245
ISSN：
1861-4728
eISSN：
1861-471X
-
Third Generation Photo-Cross-Linked Small-Molecule Affinity Matrix: A Photoactivatable and Photocleavable System Enabling Quantitative Analysis of the Photo-Cross-Linked Small Molecules and Their Target Purification
Peer-reviewed
Takahiro Suzuki, Toshitaka Okamura, Takenori Tomohiro, Yoshiharu Iwabuchi, Naoki Kanoh
BIOCONJUGATE CHEMISTRY 26 (3) 389-395 2015/03
DOI：
10.1021/bc500559e
ISSN：
1043-1802
-
Development of an Azanoradamantane-Type Nitroxyl Radical Catalyst for Class-Selective Oxidation of Alcohols
Peer-reviewed
Ryusuke Doi, Masatoshi Shibuya, Tsukasa Murayama, Yoshihiko Yamamoto, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 80 (1) 401-413 2015/01
DOI：
10.1021/jo502426p
ISSN：
0022-3263
-
Highly Enantioselective Organocatalytic Oxidative Kinetic Resolution of Secondary Alcohols Using Chiral Alkoxyamines as Precatalysts: Catalyst Structure, Active Species, and Substrate Scope
Peer-reviewed
Keiichi Murakami, Yusuke Sasano, Masaki Tomizawa, Masatoshi Shibuya, Eunsang Kwon, Yoshiharu Iwabuchi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 136 (50) 17591-17600 2014/12
DOI：
10.1021/ja509766f
ISSN：
0002-7863
-
ChemInform Abstract: Total Synthesis of the Proposed Structure of Heronamide C.
Kohei Sakanishi, Shunya Itoh, Ryosuke Sugiyama, Shinichi Nishimura, Hideaki Kakeya, Yoshiharu Iwabuchi, Naoki Kanoh
ChemInform 45 (49) no-no 2014/11
Publisher:
Wiley
DOI：
10.1002/chin.201449210
ISSN：
0931-7597
-
Mechanistic Insight into Aerobic Alchol Oxidation Using NOx-Nitroxide Catalysis Based on Catalyst Structure-Activity Relationships
Peer-reviewed
Masatoshi Shibuya, Shota Nagasawa, Yuji Osada, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 79 (21) 10256-10268 2014/11
DOI：
10.1021/jo501862k
ISSN：
0022-3263
eISSN：
1520-6904
-
A Concise and Unified Strategy for Synthesis of the C1-C18 Macrolactone Fragments of FD-891, FD-892 and Their Analogues: Formal Total Synthesis of FD-891
Peer-reviewed
Naoki Kanoh, Ayano Kawamata, Tomohiro Itagaki, Yuta Miyazaki, Kenzo Yahata, Eunsang Kwon, Yoshiharu Iwabuchi
ORGANIC LETTERS 16 (19) 5216-5219 2014/10
DOI：
10.1021/ol502633j
ISSN：
1523-7060
eISSN：
1523-7052
-
Strong inhibitory effects of curcumin and its demethoxy analog on Escherichia coli ATP synthase F-1 sector
Mizuki Sekiya, Eiko Chiba, Momoe Satoh, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Masamitsu Futai, Mayumi Nakanishi-Matsui
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 70 241-245 2014/09
DOI：
10.1016/j.ijbiomac.2014.06.055
ISSN：
0141-8130
eISSN：
1879-0003
-
Eu(OTf)(3)-Catalyzed Highly Regioselective Nucleophilic Ring Opening of 2,3-Epoxy Alcohols: An Efficient Entry to 3-Substituted 1,2-Diol Derivatives
Shun-ichiro Uesugi, Tsubasa Watanabe, Takamichi Imaizumi, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
ORGANIC LETTERS 16 (17) 4408-4411 2014/09
DOI：
10.1021/ol502264y
ISSN：
1523-7060
eISSN：
1523-7052
-
Highly Enantioselective Organocatalytic Oxidative Kinetic Resolution of Secondary Alcohols Using Chirally Modified AZADOs (vol 11, pg 1829, 2009)
Peer-reviewed
Masaki Tomizawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
ORGANIC LETTERS 16 (18) 4968-4968 2014/09
DOI：
10.1021/ol502543r
ISSN：
1523-7060
eISSN：
1523-7052
-
NAD(P)+選択的検出プローブを利用したチトクロムP450基質スクリーニング法の構築と評価
守谷 崇, 川又 綾乃, 高橋 裕介, 岩渕 好治, 叶 直樹
日本薬学会年会要旨集 134年会 (2) 70-70 2014/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
抗腫瘍性マクロライドFD-891およびFD-892の系統的合成研究 マクロラクトン部の構築
板垣 友宏, 川又 綾乃, 宮崎 雄太, 八幡 健三, 叶 直樹, 岩渕 好治
日本薬学会年会要旨集 134年会 (2) 137-137 2014/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
ENANTIOSELECTIVE INTRAMOLECULAR AZA-SPIROANNULATION ONTO BENZOFURANS USING CHIRAL RHODIUM CATALYSIS
Takuro Shibuta, Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, Tohru Taniguchi, Kenji Monde, Yoshiharu Iwabuchi
HETEROCYCLES 89 (3) 631-639 2014/03
DOI：
10.3987/COM-14-12941
ISSN：
0385-5414
eISSN：
1881-0942
-
Total Synthesis of the Proposed Structure of Heronamide C
Kohei Sakanishi, Shunya Itoh, Ryosuke Sugiyama, Shinichi Nishimura, Hideaki Kakeya, Yoshiharu Iwabuchi, Naoki Kanoh
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY 2014 (7) 1376-1380 2014/03
DOI：
10.1002/ejoc.201301487
ISSN：
1434-193X
eISSN：
1099-0690
-
Highly Chemoselective Aerobic Oxidation of Amino Alcohols into Amino Carbonyl Compounds
Yusuke Sasano, Shota Nagasawa, Mai Yamazaki, Masatoshi Shibuya, Jaiwook Park, Yoshiharu Iwabuchi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53 (12) 3236-3240 2014/03
DOI：
10.1002/anie.201309634
ISSN：
1433-7851
eISSN：
1521-3773
-
Discovery and Exploitation of AZADO: The Highly Active Catalyst for Alcohol Oxidation
Yoshiharu Iwabuchi
CHEMICAL & PHARMACEUTICAL BULLETIN 61 (12) 1197-1213 2013/12
DOI：
10.1248/cpb.c13-00456
ISSN：
0009-2363
-
On the Origin of cine-Substitution in the Stille Coupling of Trisubstituted Iodoalkene and trans-Vinylstannane
Naoki Kanoh, Yutaro Ohno, Tomohiro Itagaki, Hayato Fukuda, Yoshiharu Iwabuchi
SYNLETT 24 (20) 2660-2664 2013/12
DOI：
10.1055/s-0033-1339899
ISSN：
0936-5214
eISSN：
1437-2096
-
3-Methyl-4-oxa-5-azahomoadamantane: Alkoxyamine-Type Organocatalyst for Alcohol Oxidation
Yusuke Sasano, Keiichi Murakami, Tomohiro Nishiyama, Eunsang Kwon, Yoshiharu Iwabuchi
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 52 (48) 12624-12627 2013/11
DOI：
10.1002/anie.201307144
ISSN：
1433-7851
eISSN：
1521-3773
-
C-H MODIFICATION OF 2-AZAADAMANTANE: SYNTHESIS OF C5-FUNCTIONALIZED AZADOS FOR ADVANCED USE
Yusuke Sasano, Tomohiro Nishiyama, Masaki Tomizawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
HETEROCYCLES 87 (10) 2109-2118 2013/10
DOI：
10.3987/COM-13-12804
ISSN：
0385-5414
eISSN：
1881-0942
-
Development of Simple and Highly Efficient Aerobic Oxidation Method by Tuning Electrochemical and Steric Properties of Nitroxyl Radical Catalysts
Peer-reviewed
Masatoshi Shibuya, Yoshiharu Iwabuchi
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 71 (5) 515-525 2013/05
DOI：
10.5059/yukigoseikyokaishi.71.515
ISSN：
0037-9980
-
Concise Entry to Chiral 5-(4-Hydroxybutyl)-2(5H)-furanone via HTIB-Mediated Novel Oxidative Fragmentation: Formal Total Synthesis of (+)-Dubiusamine A
Peer-reviewed
Muneo Kawasumi, Yoshiharu Iwabuchi
ORGANIC LETTERS 15 (7) 1788-1790 2013/04
DOI：
10.1021/ol4005239
ISSN：
1523-7060
-
抗腫瘍性マクロライドFD-891およびFD-892の系統的合成研究
川又 綾乃, 宮崎 雄太, 八幡 健三, 叶 直樹, 岩渕 好治
日本薬学会年会要旨集 133年会 (2) 80-80 2013/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
新規PI(3,5)P2誘導体の合成とvicenistatinの作用機構解析への応用
真野 昂裕, 岩渕 好治, 臼井 健郎, 叶 直樹
日本薬学会年会要旨集 133年会 (2) 91-91 2013/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
An improved fluorogenic NAD(P)(+) detection method using 2-acetylbenzofuran: its origin and application
Takashi Moriya, Ayano Kawamata, Yusuke Takahashi, Yoshiharu Iwabuchi, Naoki Kanoh
CHEMICAL COMMUNICATIONS 49 (98) 11500-11502 2013
DOI：
10.1039/c3cc47264g
ISSN：
1359-7345
eISSN：
1364-548X
-
Dual Structure-Activity Relationship of Osteoclastogenesis Inhibitor Methyl Gerfelin Based on TEG Scanning
Peer-reviewed
Naoki Kanoh, Takahiro Suzuki, Makoto Kawatani, Yasuhiro Katou, Hiroyuki Osada, Yoshiharu Iwabuchi
BIOCONJUGATE CHEMISTRY 24 (1) 44-52 2013/01
DOI：
10.1021/bc3003666
ISSN：
1043-1802
-
Synthesis and Structure-Activity Relationship of Vicenistatin, a Cytotoxic 20-Membered Macrolactam Glycoside
Peer-reviewed
Hayato Fukuda, Yuko Nishiyama, Shiina Nakamura, Yutaro Ohno, Tadashi Eguchi, Yoshiharu Iwabuchi, Takeo Usui, Naoki Kanoh
CHEMISTRY-AN ASIAN JOURNAL 7 (12) 2872-2881 2012/12
DOI：
10.1002/asia.201200615
ISSN：
1861-4728
-
Nitroxyl Radical/Phl(OAc)(2): One-Pot Oxidative Cleavage of Vicinal Diols to (Di)Carboxylic Acids
Peer-reviewed
Masatoshi Shibuya, Takuro Shibuta, Hayato Fukuda, Yoshiharu Iwabuchi
ORGANIC LETTERS 14 (19) 5010-5013 2012/10
DOI：
10.1021/ol3021435
ISSN：
1523-7060
eISSN：
1523-7052
-
Organocatalytic One-Pot Oxidative Cleavage of Terminal Diols to Dehomologated Carboxylic Acids
Peer-reviewed
Masatoshi Shibuya, Ryusuke Doi, Takuro Shibuta, Shun-ichiro Uesugi, Yoshiharu Iwabuchi
ORGANIC LETTERS 14 (19) 5006-5009 2012/10
DOI：
10.1021/ol3021429
ISSN：
1523-7060
eISSN：
1523-7052
-
Oxidation of nitroxyl radicals: electrochemical and computational studies
Peer-reviewed
Masatoshi Shibuya, Fabio Pichierri, Masaki Tomizawa, Shota Nagasawa, Iwao Suzuki, Yoshiharu Iwabuchi
TETRAHEDRON LETTERS 53 (16) 2070-2073 2012/04
DOI：
10.1016/j.tetlet.2012.02.033
ISSN：
0040-4039
-
Catalytic Oxidation of Silyl Enol Ethers to 1,2-Diketones Employing Nitroxyl Radicals
Peer-reviewed
Masaki Hayashi, Masatoshi Shibuya, Yoshiharu Iwabuchi
SYNLETT (7) 1025-1030 2012/04
DOI：
10.1055/s-0031-1290528
ISSN：
0936-5214
eISSN：
1437-2096
-
Oxidation of Alcohols to Carbonyl Compounds with Diisopropyl Azodicarboxylate Catalyzed by Nitroxyl Radicals
Peer-reviewed
Masaki Hayashi, Masatoshi Shibuya, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 77 (6) 3005-3009 2012/03
DOI：
10.1021/jo300088b
ISSN：
0022-3263
eISSN：
1520-6904
-
Challenges in establishing potent cancer chemotherapy using newly synthesized 1,5-Diaryl-3-Oxo-1,4-Pentadiene analogs of curcumin
Hiroyuki Shibata, Yoshiharu Iwabuchi
Curcumin: Biosynthesis, Medicinal Uses and Health Benefits 177-191 2012/02/01
-
Oxidative Conversion of Silyl Enol Ethers to alpha,beta-Unsaturated Ketones Employing Oxoammonium Salts
Peer-reviewed
Masaki Hayashi, Masatoshi Shibuya, Yoshiharu Iwabuchi
ORGANIC LETTERS 14 (1) 154-157 2012/01
DOI：
10.1021/ol2029417
ISSN：
1523-7060
eISSN：
1523-7052
-
Detection of Cytochrome P450 Substrates by Using a Small-Molecule Droplet Array on an NADH-Immobilized Solid Surface
Hiroshi Takayama, Shunji Takahashi, Takashi Moriya, Hiroyuki Osada, Yoshiharu Iwabuchi, Naoki Kanoh
CHEMBIOCHEM 12 (18) 2748-2752 2011/12
DOI：
10.1002/cbic.201100541
ISSN：
1439-4227
-
9-Azanoradamantane N-Oxyl (Nor-AZADO): A Highly Active Organocatalyst for Alcohol Oxidation
Peer-reviewed
Masaki Hayashi, Yusuke Sasano, Shota Nagasawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
CHEMICAL & PHARMACEUTICAL BULLETIN 59 (12) 1570-1573 2011/12
DOI：
10.1248/cpb.59.1570
ISSN：
0009-2363
-
Detection of Cytochrome P450 Substrates by Using a Small-Molecule Droplet Array on an NADH-Immobilized Solid Surface
Peer-reviewed
Hiroshi Takayama, Shunji Takahashi, Takashi Moriya, Hiroyuki Osada, Yoshiharu Iwabuchi, Naoki Kanoh
CHEMBIOCHEM 12 (18) 2748-2752 2011/12
DOI：
10.1002/cbic.201100541
ISSN：
1439-4227
-
Practical Preparation Methods for Highly Active Azaadamantane-Nitroxyl-Radical-Type Oxidation Catalysts
Peer-reviewed
Masatoshi Shibuya, Yusuke Sasano, Masaki Tomizawa, Toshimasa Hamada, Masami Kozawa, Noriaki Nagahama, Yoshiharu Iwabuchi
SYNTHESIS-STUTTGART (21) 3418-3425 2011/11
DOI：
10.1055/s-0030-1260257
ISSN：
0039-7881
-
Novel Curcumin Analogs, GO-Y030 and GO-Y078, Are Multitargeted Agents with Enhanced Abilities for Multiple Myeloma
Peer-reviewed
Chieko Kudo, Hiroyuki Yamakoshi, Atsuko Sato, Hisatsugu Ohori, Chikashi Ishioka, Yoshiharu Iwabuchi, Hiroyuki Shibata
ANTICANCER RESEARCH 31 (11) 3719-3726 2011/11
ISSN：
0250-7005
-
Highly active organocatalyst for oxidation of alcohols
Peer-reviewed
Masaki Hayashi, Yoshiharu Iwabuchi
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242 2011/08
ISSN：
0065-7727
-
Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030
L. Lin, Y. Liu, H. Li, P-K Li, J. Fuchs, H. Shibata, Y. Iwabuchi, J. Lin
BRITISH JOURNAL OF CANCER 105 (2) 212-220 2011/07
DOI：
10.1038/bjc.2011.200
ISSN：
0007-0920
-
High-performance liquid chromatography with photodiode array detection for determination of nobiletin content in the brain and serum of mice administrated the natural compound
Peer-reviewed
Daisuke Saigusa, Masatoshi Shibuya, Daisuke Jinno, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Akihito Yokosuka, Yoshihiro Mimaki, Akira Naganuma, Yasushi Ohizumi, Yoshihisa Tomioka, Tohru Yamakuni
ANALYTICAL AND BIOANALYTICAL CHEMISTRY 400 (10) 3635-3641 2011/07
DOI：
10.1007/s00216-011-5031-2
ISSN：
1618-2642
eISSN：
1618-2650
-
Concise Entry to Both Enantiomers of 8-Oxabicyclo[3.2.1]oct-3-en-2-one Based on Novel Oxidative Etherification: Formal Synthesis of (+)-Sundiversifolide
Peer-reviewed
Muneo Kawasumi, Naoki Kanoh, Yoshiharu Iwabuchi
ORGANIC LETTERS 13 (14) 3620-3623 2011/07
DOI：
10.1021/ol201273b
ISSN：
1523-7060
eISSN：
1523-7052
-
Asymmetric Total Synthesis of (-)-Scabronine G via Intramolecular Double Michael Reaction and Prins Cyclization
Peer-reviewed
Naoki Kanoh, Kohei Sakanishi, Emiko Iimori, Ken'ichi Nishimura, Yoshiharu Iwabuchi
ORGANIC LETTERS 13 (11) 2864-2867 2011/06
DOI：
10.1021/ol200873y
ISSN：
1523-7060
-
Synthesis of 86 species of 1,5-diaryl-3-oxo-1,4-pentadienes analogs of curcumin can yield a good lead in vivo
Chieko Kudo, Hiroyuki Yamakoshi, Atsuko Sato, Hiroshi Nanjo, Hisatsugu Ohori, Chikashi Ishioka, Yoshiharu Iwabuchi, Hiroyuki Shibata
BMC Pharmacology 11 2011/05/28
DOI：
10.1186/1471-2210-11-4
ISSN：
1471-2210
-
Curcumin analog GO-Y030 is a novel inhibitor of IKK beta that suppresses NF-kappa B signaling and induces apoptosis
Peer-reviewed
Atsuko Sato, Chieko Kudo, Hiroyuki Yamakoshi, Yoshihiko Uehara, Hisatsugu Ohori, Chikashi Ishioka, Yoshiharu Iwabuchi, Hiroyuki Shibata
CANCER SCIENCE 102 (5) 1045-1051 2011/05
DOI：
10.1111/j.1349-7006.2011.01886.x
ISSN：
1347-9032
-
Highly Efficient, Organocatalytic Aerobic Alcohol Oxidation
Peer-reviewed
Masatoshi Shibuya, Yuji Osada, Yusuke Sasano, Masaki Tomizawa, Yoshiharu Iwabuchi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 133 (17) 6497-6500 2011/05
DOI：
10.1021/ja110940c
ISSN：
0002-7863
-
HPLC/PDA法を用いた体内動態解析による抗アルツハイマー病天然薬物ノビレチンの脳内移行の証明
三枝 大輔, 中島 晶, 鐵 尚美, 澁谷 正俊, 山越 博幸, 岩渕 好治, 横須賀 章人, 指田 豊, 三巻 祥浩, 永沼 章, 大泉 康, 富岡 佳久
日本薬学会年会要旨集 131年会 (4) 139-139 2011/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
生体内transアコニット酸生成機構解明のための有機酸高感度定量法の確立
松本 周平, 三枝 大輔, 竹田 千尋, 鈴木 直人, 澁谷 正俊, 岩渕 好治, 富岡 佳久
日本薬学会年会要旨集 131年会 (4) 288-288 2011/03
Publisher:
(公社)日本薬学会
ISSN：
0918-9823
-
Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway
Peer-reviewed
Takumi Chinen, Yoko Nagumo, Tsubasa Watanabe, Takamichi Imaizumi, Masatoshi Shibuya, Takao Kataoka, Naoki Kanoh, Yoshiharu Iwabuchi, Takeo Usui
TOXICOLOGY LETTERS 199 (3) 341-346 2010/12
DOI：
10.1016/j.toxlet.2010.09.017
ISSN：
0378-4274
eISSN：
1879-3169
-
Concise Total Synthesis of Vicenistatin
Peer-reviewed
Hayato Fukuda, Shiina Nakamura, Tadashi Eguchi, Yoshiharu Iwabuchi, Naoki Kanoh
SYNLETT (17) 2589-2592 2010/10
DOI：
10.1055/s-0030-1258574
ISSN：
0936-5214
-
AN ENANTIO- AND DIASTEREOCONTROLLED SYNTHESIS OF (-)-SALINOSPORAMIDE A
Peer-reviewed
Yosuke Sato, Hayato Fukuda, Masaki Tomizawa, Tomohito Masaki, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
HETEROCYCLES 81 (10) 2239-2246 2010/10
DOI：
10.3987/COM-10-12042
ISSN：
0385-5414
eISSN：
1881-0942
-
KSRP/FUBP2 Is a Binding Protein of GO-Y086, a Cytotoxic Curcumin Analogue
Peer-reviewed
Hiroyuki Yamakoshi, Naoki Kanoh, Chieko Kudo, Atsuko Sato, Kazunori Ueda, Makoto Muroi, Shunsuke Kon, Masanobu Satake, Hisatsugu Ohori, Chikashi Ishioka, Yoshiteru Oshima, Hiroyuki Osada, Natsuko Chiba, Hiroyuki Shibata, Yoshiharu Iwabuchi
ACS MEDICINAL CHEMISTRY LETTERS 1 (6) 273-276 2010/09
DOI：
10.1021/ml1000454
ISSN：
1948-5875
-
Total Synthesis and Determination of the Absolute Configuration of (-)-Idesolide
Peer-reviewed
Hiroyuki Yamakoshi, Masatoshi Shibuya, Masaki Tomizawa, Yuji Osada, Naoki Kanoh, Yoshiharu Iwabuchi
ORGANIC LETTERS 12 (5) 980-983 2010/03
DOI：
10.1021/ol9029676
ISSN：
1523-7060
eISSN：
1523-7052
-
Syntheses and Biological Evaluation of Irciniastatin A and the C1-C2 Alkyne Analogue
Peer-reviewed
Tsubasa Watanabe, Takamichi Imaizumi, Takumi Chinen, Yoko Nagumo, Masatoshi Shibuya, Takeo Usui, Naoki Kanoh, Yoshiharu Iwabuchi
ORGANIC LETTERS 12 (5) 1040-1043 2010/03
DOI：
10.1021/ol1000389
ISSN：
1523-7060
eISSN：
1523-7052
-
Structure-activity relationship of C-5-curcuminoids and synthesis of their molecular probes thereof
Peer-reviewed
Hiroyuki Yamakoshi, Hisatsugu Ohori, Chieko Kudo, Atsuko Sato, Naoki Kanoh, Chikashi Ishioka, Hiroyuki Shibata, Yoshiharu Iwabuchi
BIOORGANIC & MEDICINAL CHEMISTRY 18 (3) 1083-1092 2010/02
DOI：
10.1016/j.bmc.2009.12.045
ISSN：
0968-0896
eISSN：
1464-3391
-
Cleavable Linker for Photo-Cross-Linked Small-Molecule Affinity Matrix
Peer-reviewed
Naoki Kanoh, Hiroshi Takayama, Kaori Honda, Takashi Moriya, Takayuki Teruya, Siro Simizu, Hiroyuki Osada, Yoshiharu Iwabuchi
BIOCONJUGATE CHEMISTRY 21 (1) 182-186 2010/01
DOI：
10.1021/bc900316q
ISSN：
1043-1802
-
Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas
Brian Hutzen, Lauren Friedman, Matthew Sobo, Li Lin, Ling Cen, Stephanie De Angelis, Hiroyuki Yamakoshi, Hiroyuki Shibata, Yoshiharu Iwabuchi, Jiayuh Lin
INTERNATIONAL JOURNAL OF ONCOLOGY 35 (4) 867-872 2009/10
DOI：
10.3892/ijo_00000401
ISSN：
1019-6439
eISSN：
1791-2423
-
Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas
Peer-reviewed
Brian Hutzen, Lauren Friedman, Matthew Sobo, Li Lin, Ling Cen, Stephanie De Angelis, Hiroyuki Yamakoshi, Hiroyuki Shibata, Yoshiharu Iwabuchi, Jiayuh Lin
INTERNATIONAL JOURNAL OF ONCOLOGY 35 (4) 867-872 2009/10
DOI：
10.3892/ijo_00000401
ISSN：
1019-6439
eISSN：
1791-2423
-
An Expedient Route to a Potent Gastrin/CCK-B Receptor Antagonist (+)-AG-041R
Peer-reviewed
Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 74 (19) 7522-7524 2009/10
DOI：
10.1021/jo901352u
ISSN：
0022-3263
-
4 '-Demethylnobiletin, a Bioactive Metabolite of Nobiletin Enhancing PKA/ERK/CREB Signaling, Rescues Learning Impairment Associated with NMDA Receptor Antagonism via Stimulation of the ERK Cascade
Peer-reviewed
Md Al Rahim, Akira Nakajima, Daisuke Saigusa, Naomi Tetsu, Yuji Maruyama, Masatoshi Shibuya, Hiroyuki Yamakoshi, Yoshihisa Tomioka, Yoshiharu Iwabuchi, Yasushi Ohizumi, Tohru Yamakuni
BIOCHEMISTRY 48 (32) 7713-7721 2009/08
DOI：
10.1021/bi901088w
ISSN：
0006-2960
-
An Expeditious Entry to 9-Azabicyclo[3.3.1]nonane N-Oxyl (ABNO): Another Highly Active Organocatalyst for Oxidation of Alcohols
Peer-reviewed
Masatoshi Shibuya, Masaki Tomizawa, Yusuke Sasano, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 74 (12) 4619-4622 2009/06
DOI：
10.1021/jo900486w
ISSN：
0022-3263
-
Newly synthesized curcumin analog has improved potential to prevent colorectal carcinogenesis in vivo
Peer-reviewed
Hiroyuki Shibata, Hiroyuki Yamakoshi, Atsuko Sato, Hisatsugu Ohori, Yuichi Kakudo, Chieko Kudo, Yayoi Takahashi, Mika Watanabe, Hiroshi Takano, Chikashi Ishioka, Tetsuo Noda, Yoshiharu Iwabuchi
CANCER SCIENCE 100 (5) 956-960 2009/05
DOI：
10.1111/j.1349-7006.2009.01127.x
ISSN：
1347-9032
-
Therapeutic potential of newly synthesized curcumin analogs
Peer-reviewed
Hiroyuki Shibata, Chieko Kudo, Atsuko Sato, Hisatsugu Ohori, Hiroyuki Yamakoshi, Chikashi Ishioka, Yoshiharu Iwabuchi
CANCER RESEARCH 69 2009/05
ISSN：
0008-5472
eISSN：
1538-7445
-
Synthetic Studies on Daphnicyclidin A: Enantiocontrolled Construction of the BCD Ring System
Peer-reviewed
Shuhei Ikeda, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
ORGANIC LETTERS 11 (8) 1833-1836 2009/04
DOI：
10.1021/ol9003405
ISSN：
1523-7060
eISSN：
1523-7052
-
Highly Enantioselective Organocatalytic Oxidative Kinetic Resolution of Secondary Alcohols Using Chirally Modified AZADOs
Peer-reviewed
Masaki Tomizawa, Masatoshi Shibuya, Yoshiharu Iwabuchi
ORGANIC LETTERS 11 (8) 1829-1831 2009/04
DOI：
10.1021/ol900441f
ISSN：
1523-7060
eISSN：
1523-7052
-
FLEXIBLE ACCESS TO MONOTERPENOID INDOLE ALKALOIDS USING A CYCLOPENTANOID CHIRAL BUILDING BLOCK
Peer-reviewed
Masato Hayashi, Keiichi Motosawa, Atsushi Satoh, Masatoshi Shibuya, Kunio Ogasawara, Yoshiharu Iwabuchi
HETEROCYCLES 77 (2) 855-863 2009/02
DOI：
10.3987/COM-08-S(F)120
ISSN：
0385-5414
eISSN：
1881-0942
-
Activation of Endothelial Nitric Oxide Synthase by a Vanadium Compound Ameliorates Pressure Overload-Induced Cardiac Injury in Ovariectomized Rats
Peer-reviewed
Shenuarin Bhuiyan, Norifumi Shioda, Masatoshi Shibuya, Yoshiharu Iwabuchi, Kohji Fukunaga
HYPERTENSION 53 (1) 57-63 2009/01
DOI：
10.1161/HYPERTENSIONAHA.108.118356
ISSN：
0194-911X
eISSN：
1524-4563
-
Oxoammonium salt/NaClO2: an expedient, catalytic system for one-pot oxidation of primary alcohols to carboxylic acids with broad substrate applicability
Peer-reviewed
Masatoshi Shibuya, Takahisa Sato, Masaki Tomizawa, Yoshiharu Iwabuchi
CHEMICAL COMMUNICATIONS (13) 1739-1741 2009
DOI：
10.1039/b822944a
ISSN：
1359-7345
eISSN：
1364-548X
-
Syntheses of naturally occurring cytotoxic [7.7]paracyclophanes, (-)-cylindrocyclophane A and its enantiomer, and implications for biological activity
Peer-reviewed
Hiroyuki Yamakoshi, Fumiya Ikarashi, Masataka Minami, Masatoshi Shibuya, Tsutomu Sugahara, Naoki Kanoh, Hisatsugu Ohori, Hiroyuki Shibata, Yoshiharu Iwabuchi
ORGANIC & BIOMOLECULAR CHEMISTRY 7 (18) 3772-3781 2009
DOI：
10.1039/b909646a
ISSN：
1477-0520
eISSN：
1477-0539
-
Highly enantioselective intramolecular aza-spiroannulation onto indoles using chiral rhodium catalysis: asymmetric entry to the spiro-beta-lactam core of chartellines
Peer-reviewed
Shigeki Sato, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
CHEMICAL COMMUNICATIONS (41) 6264-6266 2009
DOI：
10.1039/b913770j
ISSN：
1359-7345
eISSN：
1364-548X
-
Exploration and Exploitation of Synthetic Use of Oxoammonium Ions in Alcohol Oxidation
Peer-reviewed
Yoshiharu Iwabuchi
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 66 (11) 1076-1084 2008/11
DOI：
10.5059/yukigoseikyokaishi.66.1076
ISSN：
0037-9980
-
TEMPO/NalO(4)-SiO2: A Catalytic Oxidative Rearrangement of Tertiary Allylic Alcohols to beta-Substituted alpha,beta-Unsaturated Ketones
Peer-reviewed
Masatoshi Shibuya, Masaki Tomizawa, Yoshiharu Iwabuchi
ORGANIC LETTERS 10 (21) 4715-4718 2008/11
DOI：
10.1021/ol801673r
ISSN：
1523-7060
-
Efficient Entry to the Pyrroloquinoline Core of Martinella Alkaloids via Novel Base-catalyzed Mukaiyama-Mannich Reaction
Peer-reviewed
Shuhei Ikeda, Masatoshi Shibuya, Naoki Kanoh, Yoshiharu Iwabuchi
CHEMISTRY LETTERS 37 (9) 962-963 2008/09
DOI：
10.1246/cl.2008.962
ISSN：
0366-7022
eISSN：
1348-0715
-
Distribution of photo-cross-linked products from 3-aryl-3-trifluoromethyldiazirines and alcohols
Peer-reviewed
Naoki Kanoh, Takemichi Nakamura, Kaori Honda, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Osada
TETRAHEDRON 64 (24) 5692-5698 2008/06
DOI：
10.1016/j.tet.2008.04.031
ISSN：
0040-4020
-
Oxidative rearrangement of tertiary allylic alcohols employing oxoammonium salts
Peer-reviewed
Masatoshi Shibuya, Masaki Tomizawa, Yoshiharu Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 73 (12) 4750-4752 2008/06
DOI：
10.1021/jo800634r
ISSN：
0022-3263
-
Chemoenzymatic preparation of functionalized bicyclo[3.2.1]octenone and practical utilization
Peer-reviewed
Shinichiro Ito, Ayako Tosaka, Keisuke Hanada, Masatoshi Shibuya, Kunio Ogasawara, Yoshiharu Iwabuchi
TETRAHEDRON-ASYMMETRY 19 (2) 176-+ 2008/02
DOI：
10.1016/j.tetasy.2007.12.009
ISSN：
0957-4166
-
Neuroprotective effect of a vanadium compound and melatonin in MPTP-induced dopaminergic defects in mice
Peer-reviewed
Jiro Kasahara, Tomofumi Nagai, Masatoshi Shibuya, Yoshiharu Iwabuchi, Norie Araki, Kohji Fukunaga
NEUROSCIENCE RESEARCH 61 S265-S265 2008
ISSN：
0168-0102
-
Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression
Md. Shenuarin Bhuiyan, Masatoshi Shibuya, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Yosiharu Iwabuchi, Kohji Fukunaga
EUROPEAN JOURNAL OF PHARMACOLOGY 571 (2-3) 180-188 2007/10
DOI：
10.1016/j.ejphar.2007.05.046
ISSN：
0014-2999
-
25 Asymmetric Total Synthesis of Martinella Alkaloids
Ikeda Shuhei, Shibuya Masatoshi, Iwashita Masaya, Saitoh Masaki, Nakahata Norimichi, Iwabuchi Yoshiharu
Symposium on the Chemistry of Natural Products, symposium papers (49) 145-150 2007/08/24
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.49.0_145
-
Activation of phosphatidylinositol 3-kinase/protein kinase B pathway by a vanadyl compound mediates its neuroprotective effect in mouse brain ischemia
N. Shioda, T. Ishigami, F. Han, S. Moriguchi, M. Shibuya, Y. Iwabuchi, K. Fukunag
NEUROSCIENCE 148 (1) 221-229 2007/08
DOI：
10.1016/j.neuroscience.2007.05.040
ISSN：
0306-4522
-
Synthesis of an enantiomeric DNA oligomer and its T-HgII-T base-pair formation.
Kaichiro Haruta, Yoshiyuki Tanaka, Takuya Kawamura, Yoshinori Kondo, Akira Ono, Hiroyuki Yamakoshi, Naoki Kanoh, Yoshiharu Iwabuchi
Nucleic acids symposium series (2004) 187-188 2007/01/01
-
Asymmetric total synthesis of martinelline and martinellic acid
Peer-reviewed
Shuhei Ikeda, Masatoshi Shibuya, Yoshiharu Iwabuchi
CHEMICAL COMMUNICATIONS (5) 504-506 2007
DOI：
10.1039/b611121a
ISSN：
1359-7345
-
Enantio- and diastereocontrolled synthesis of (+)-juvabione employing organocatalytic desymmetrisation and photoinduced fragmentation
Peer-reviewed
Noriaki Itagaki, Yoshiharu Iwabuchi
CHEMICAL COMMUNICATIONS (11) 1175-1176 2007
DOI：
10.1039/b616641e
ISSN：
1359-7345
-
Protective effects of nobiletin and its derivative on NMDA receptor antagonist MK-801-induced learning and memory deficits in mice.
Peer-reviewed
Akira Nakajima, Tohru Yamakuni, Yuji Maruyama, Kentaro Matsuzaki, Masatoshi Shibuya, Yoshiharu Iwabuchi, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Yasushi Ohizumi
JOURNAL OF PHARMACOLOGICAL SCIENCES 103 179P-179P 2007
ISSN：
1347-8613
-
Total synthesis of (-)-dihydrocorynantheol using bicyclo[3.2.1]octenone chiral building block
Peer-reviewed
Ayako Tosaka, Shinichiro Ito, Norio Miyazawa, Masatoshi Shibuya, Kunio Ogasawara, Yoshiharu Iwabuchi
HETEROCYCLES 70 153-+ 2006/12
DOI：
10.3987/COM-06-S(W)49
ISSN：
0385-5414
eISSN：
1881-0942
-
Synthesis and biological analysis of new curcumin analogues bearing an enhanced potential for the medicinal treatment of cancer
Peer-reviewed
Hisatsugu Ohori, Hiroyuki Yamakoshi, Masaki Tomizawa, Masatoshi Shibuya, Yuichi Kakudo, Atsuko Takahashi, Shin Takahashi, Satoshi Kato, Takao Suzuki, Chikashi Ishioka, Yoshiharu Iwabuchi, Hiroyuki Shibata
MOLECULAR CANCER THERAPEUTICS 5 (10) 2563-2571 2006/10
DOI：
10.1158/1535-7163.MCT-06-0174
ISSN：
1535-7163
-
P-116 The Asymmetric Total Synthesis of Martinelline
Ikeda Shuhei, Sugawara Tsuyoshi, Shibuya Masatoshi, Iwabuchi Yoshiharu
International Symposium on the Chemistry of Natural Products 2006 "P-116" 2006/07/23
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/intnaturalprod.2006.0__P-116_
-
2-azaadamantane N-oxyl (AZADO) and 1-Me-AZADO: Highly efficient organocatalysts for oxidation of alcohols
Peer-reviewed
Masatoshi Shibuya, Masaki Tomizawa, Iwao Suzuki, Yoshiharu Iwabuchi
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 128 (26) 8412-8413 2006/07
DOI：
10.1021/ja0620336
ISSN：
0002-7863
-
Identification and possibility of new curcumin analogs bearing the dual enhanced potentials for the degradation of oncoproteins and the stabilization of p53
Hisatsugu Ohori, Hiroyuki Shibata, Yuichi Kakudo, Atsuko Maeda, Yoshiharu Iwabuchi, Chikashi Ishioka
CANCER RESEARCH 66 (8) 2006/04
ISSN：
0008-5472
eISSN：
1538-7445
-
An enantio- and diastereocontrolled synthesis of (+)-7-deoxy-trans-dihydronarciclasine (PII:S0385-5414(05)80388-0)
Takashi Fujimura, Masatoshi Shibuya, Kunio Ogasawara, Yoshiharu Iwabuchi
Heterocycles 68 451 2006/02/01
ISSN：
0385-5414
-
beta-isocupreidine-hexafluoroisopropyl acrylate method for asymmetric Baylis-Hillman reactions
A Nakano, S Kawahara, S Akamatsu, K Morokuma, M Nakatani, Y Iwabuchi, K Takahashi, J Ishihara, S Hatakeyama
TETRAHEDRON 62 (2-3) 381-389 2006/01
DOI：
10.1016/j.tet.2005.09.072
ISSN：
0040-4020
-
An enantio- and diastereocontrolled synthesis of (+)-7deoxy-trans-dihydronarciclasine
T Fujimura, M Shibuya, K Ogasawara, Y Iwabuchi
HETEROCYCLES 66 167-173 2005/12
DOI：
10.3987/COM-05-S(K)68
ISSN：
0385-5414
-
Synthesis of an enantiocomplementary catalyst of beta-isocupreidine (beta-ICD) from quinine
A Nakano, M Ushiyama, Y Iwabuchi, S Hatakeyama
ADVANCED SYNTHESIS & CATALYSIS 347 (14) 1790-1796 2005/11
DOI：
10.1002/adsc.200505138
ISSN：
1615-4150
-
Erratum: Expedient synthesis of potent cannabinoid receptor agonist (Organic Letters) (4181-4183)
Noriaki Itagaki, Tsutomu Sugahara, Yoshiharu Iwabuchi
Organic Letters 7 4785 2005/10/13
ISSN：
1523-7060
-
P-50 Studies toward Total Synthesis of (+)-Martinelline
Ikeda Shuhei, Shibuya Masatoshi, Iwabuchi Yoshiharu
Symposium on the Chemistry of Natural Products, symposium papers (47) 589-594 2005/09/15
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.47.0_589
-
Organocatalytic entry to chiral bicyclo[3.n.1]alkanones via direct asymmetric intramolecular aldolization
N Itagaki, M Kimura, T Sugahara, Y Iwabuchi
ORGANIC LETTERS 7 (19) 4185-4188 2005/09
DOI：
10.1021/ol051569d
ISSN：
1523-7060
-
Expedient synthesis of potent cannabinoid receptor agonist (-)-CP55,940
N Itagaki, T Sugahara, Y Iwabuchi
ORGANIC LETTERS 7 (19) 4181-4183 2005/09
DOI：
10.1021/ol051570c
ISSN：
1523-7060
-
Oxidative rearrangement of cyclic tertiary allylic alcohols with IBX in DMSO
Peer-reviewed
M Shibuya, S Ito, M Takahashi, Y Iwabuchi
ORGANIC LETTERS 6 (23) 4303-4306 2004/11
DOI：
10.1021/ol048210u
ISSN：
1523-7060
-
78(P-75) Synthetic Studies of Antitumor Cylindrocyclophanes
Minami Masataka, Sugahara Tsutomu, Iwabuchi Yosiharu
Symposium on the Chemistry of Natural Products, symposium papers (46) 443-448 2004/10/01
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.46.0_443
-
A concise route to (+)-lactacystin
Peer-reviewed
H Ooi, N Ishibashi, Y Iwabuchi, J Ishihara, S Hatakeyama
JOURNAL OF ORGANIC CHEMISTRY 69 (22) 7765-7768 2004/10
DOI：
10.1021/jo048817o
ISSN：
0022-3263
-
Total synthesis and absolute stereochemistry of pentenocin B, a novel interleukin-1 beta converting enzyme inhibitor
Peer-reviewed
T Sugahara, H Fukuda, Y Iwabuchi
JOURNAL OF ORGANIC CHEMISTRY 69 (5) 1744-1747 2004/03
DOI：
10.1021/jo035430x
ISSN：
0022-3263
-
A diastereocontrolled synthesis of perseitol using a dioxabicyclo[3.2.1]octane chiral building block
Kohei Kadota, Kunio Ogasawara, Yoshiharu Iwabuchi
Arkivoc 2003 163-170 2003/12/01
ISSN：
1424-6376
-
97(P-30) Synthesis and Determination of the Absolute Configurations of Pentenocins, Novel Inhibitors of Caspase-1
Sugahara Tsutomu, Fukuda Hayato, Iwabuchi Yoshiharu
Symposium on the Chemistry of Natural Products, symposium papers (45) 573-578 2003/09/01
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.45.0_573
-
beta-isocupreidine-catalyzed asymmetric Baylis-Hillman reaction of imines
Peer-reviewed
S Kawahara, A Nakano, T Esumi, Y Iwabuchi, S Hatakeyama
ORGANIC LETTERS 5 (17) 3103-3105 2003/08
DOI：
10.1021/ol035102j
ISSN：
1523-7060
-
Total synthesis of (+/-)-trachyspic acid and determination of the relative configuration
K Hirai, H Ooi, T Esumi, Y Iwabuchi, S Hatakeyama
ORGANIC LETTERS 5 (6) 857-859 2003/03
DOI：
10.1021/ol0275264
ISSN：
1523-7060
-
A diastereocontrolled synthesis of perseitol using a dioxabicyclo[3.2.1]octane chiral building block
Invited
Peer-reviewed
K Kadota, K Ogasawara, Y Iwabuchi
ARKIVOC (8) 163-170 2003
ISSN：
1551-7004
-
Potent antimalarial febrifugine analogues against the Plasmodium malaria parasite
H Kikuchi, H Tasaka, S Hirai, Y Takaya, Y Iwabuchi, H Ooi, S Hatakeyama, HS Kim, Y Wataya, Y Oshima
JOURNAL OF MEDICINAL CHEMISTRY 45 (12) 2563-2570 2002/06
DOI：
10.1021/jm010448q
ISSN：
0022-2623
-
Fluorescent cytochemical detection of sialidase activity using 5-bromo-4-chloroindol-3-yl-alpha-D-N-acetylneuraminic acid as the substrate
M Saito, H Hagita, Y Iwabuchi, Fujii, I, K Ikeda, M Ito
HISTOCHEMISTRY AND CELL BIOLOGY 117 (5) 453-458 2002/05
DOI：
10.1007/s00418-002-0399-x
ISSN：
0948-6143
-
Recent progress in the Morita-Baylis-Hillman reactions
Y Iwabuchi, S Hatakeyama
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN 60 (1) 2-14 2002/01
DOI：
10.5059/yukigoseikyokaishi.60.2
ISSN：
0037-9980
-
An enantio- and stereocontrolled route to epopromycin B via cinchona alkaloid-catalyzed Baylis-Hillman reaction
Peer-reviewed
Yoshiharu Iwabuchi, Tatsuya Sugihara, Tomoyuki Esumi, Susumi Hatakeyama
Tetrahedron Letters 42 (44) 7867-7871 2001/10/29
DOI：
10.1016/S0040-4039(01)01676-8
ISSN：
0040-4039
-
An enantio- and stereocontrolled synthesis of (-)-mycestericin E via cinchona alkaloid-catalyzed asymmetric Baylis-Hillman reaction
Peer-reviewed
Y Iwabuchi, M Furukawa, T Esumi, S Hatakeyama
CHEMICAL COMMUNICATIONS (19) 2030-2031 2001/10
DOI：
10.1039/b106471c
ISSN：
1359-7345
-
Synthesis and biological characterization of 1α,24,25-trihydroxy-2β-(3-hydroxypropoxy)vitamin D3 (24-hydroxylated ED-71)
Susumi Hatakeyama, Akira Kawase, Yasushi Uchiyama, Junji Maeyama, Yoshiharu Iwabuchi, Noboru Kubodera
Steroids 66 (3-5) 267-276 2001/05/01
DOI：
10.1016/S0039-128X(00)00149-5
ISSN：
0039-128X
-
A concise enantioselective synthesis of antimalarial febrifugine alkaloids
H Ooi, A Urushibara, T Esumi, Y Iwabuchi, S Hatakeyama
ORGANIC LETTERS 3 (6) 953-955 2001/03
DOI：
10.1021/ol015655z
ISSN：
1523-7060
-
A concise enantioselective synthesis of a key A-ring synthon for 1 alpha-hydroxyvitamin D-3 compounds
H Hiyamizu, H Ooi, Y Inomoto, T Esumi, Y Iwabuchi, S Hatakeyama
ORGANIC LETTERS 3 (3) 473-475 2001/02
DOI：
10.1021/ol006982u
ISSN：
1523-7060
-
Clinical features and alterations in the inferior horn sizes in lateral ventricle in Alzheimer's patients with different ApoE genotype in Japanese population
Yoshiharu Iwabuchi
Progress in Neuro-Psychopharmacology and Biological Psychiatry 2001
DOI：
10.1016/S0278-5846(01)00199-3
-
Concise synthesis of (3R,4S)-3-hydroxy-4-methyl-gamma-butyrolactone
T Nishiyama, T Nishioka, T Esumi, Y Iwabuchi, S Hatakeyama
HETEROCYCLES 54 (1) 69-72 2001/01
ISSN：
0385-5414
-
Synthesis and evaluation of A-ring diastereomers of 1α,25-dihydroxy-22-oxavitamin D3 (OCT)
Susumi Hatakeyama, Toshio Okano, Junji Maeyama, Tomoyuki Esumi, Hiroko Hiyamizu, Yoshiharu Iwabuchi, Kimie Nakagawa, Keiichi Ozono, Akira Kawase, Noboru Kubodera
Bioorganic and Medicinal Chemistry 9 (2) 403-415 2001
DOI：
10.1016/S0968-0896(00)00259-5
ISSN：
0968-0896
-
69(P-55) Exploring a New Type of Antimalarials Based on the Plant Quinazolinoid, Febrifugine
Takaya Yoshiaki, Tasaka Hidehisa, Hirai Shingo, Oshima Yoshiteru, Iwabuchi Yoshiyasu, Hatakeyama Susumi, Kim Hye-Sook, Wataya Yusuke, Fukushima Masakazu
Symposium on the Chemistry of Natural Products, symposium papers (42) 409-414 2000/10/01
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.42.0_409
-
Concise synthesis of anolignan A
MM Luo, A Matsui, T Esumi, Y Iwabuchi, S Hatakeyama
TETRAHEDRON LETTERS 41 (22) 4401-4402 2000/06
DOI：
10.1016/S0040-4039(00)00604-3
ISSN：
0040-4039
-
Stereocontrolled synthesis of (+)-lycoperdic acid based on a palladium catalyzed reaction using a serine-derived organozinc reagent
H Masaki, T Mizozoe, T Esumi, Y Iwabuchi, S Hatakeyama
TETRAHEDRON LETTERS 41 (24) 4801-4804 2000/06
DOI：
10.1016/S0040-4039(00)00719-X
ISSN：
0040-4039
-
Characterization of new conjugated metabolites in bile of rats administered 24,25-dihydroxyvitamin D-3 and 25-hydroxyvitamin D-3
T Higashi, K Miura, R Kikuchi, K Shimada, H Hiyamizu, H Ooi, Y Iwabuchi, S Hatakeyama, N Kubodera
STEROIDS 65 (5) 281-294 2000/05
DOI：
10.1016/S0039-128X(00)00087-8
ISSN：
0039-128X
-
Total synthesis of (-)-dysiherbaine
H Masaki, J Maeyama, K Kamada, T Esumi, Y Iwabuchi, S Hatakeyama
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 122 (21) 5216-5217 2000/05
DOI：
10.1021/ja000817s
ISSN：
0002-7863
-
Enantioselective synthesis of (+)-decarestrictine L from (2E,5E)-dibenzyloxy-2,5-heptadien-4-ol
T Esumi, R Kimura, M Mori, Y Iwabuchi, H Irie, S Hatakeyama
HETEROCYCLES 52 (2) 525-528 2000/02
ISSN：
0385-5414
-
Chiral amine-catalyzed asymmetric Baylis-Hillman reaction: A reliable route to highly enantiomerically enriched (alpha-methylene-beta-hydroxy)esters
Peer-reviewed
Y Iwabuchi, M Nakatani, N Yokoyama, S Hatakeyama
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 121 (43) 10219-10220 1999/11
DOI：
10.1021/ja992655+
ISSN：
0002-7863
-
Efficient route to functionalized eight-membered lactones based on intramolecular silicon-directed acylative ring-opening reactions of 3-(tetrahydro-2-furyl)propanoic acid derivatives
H Ohi, S Inoue, Y Iwabuchi, H Irie, S Hatakeyama
SYNLETT (11) 1757-1759 1999/11
ISSN：
0936-5214
-
A modified bait and switch strategy for the generation of esterolytic abzymes using concerted catalytic mechanisms
Y Iwabuchi, S Kurihara, M Oda, Fujii, I
TETRAHEDRON LETTERS 40 (29) 5341-5344 1999/07
DOI：
10.1016/S0040-4039(99)00972-7
ISSN：
0040-4039
-
Buta-2,3-dienylstannanes, effective reagents for regioselective buta-1,3-dienylation of aldehydes and acetals
MM Luo, Y Iwabuchi, S Hatakeyama
CHEMICAL COMMUNICATIONS (3) 267-268 1999/02
DOI：
10.1039/a809081e
ISSN：
1359-7345
-
Regioselective buta-1,3-dienylation of aldehydes via transmetallation of 2-tributylstannylbuta-1,3-diene
Meiming Luo, Yoshiharu Iwabuchi, Susumi Hatakeyama
Synlett (7) 1109-1111 1999
Publisher:
Georg Thieme Verlag
DOI：
10.1055/s-1999-2787
ISSN：
0936-5214
-
New metabolic pathway of (24R)-24,25-dihydroxyvitamin D3: Epimerization of the 3-hydroxy group
Tatsuya Higashi, Ryuta Kikuchi, Kanako Miura, Kazutake Shimada, Hiroko Hiyamizu, Hidenori Ooi, Yoshiharu Iwabuchi, Susumi Hatakeyama, Noboru Kubodera
Biological and Pharmaceutical Bulletin 22 (7) 767-769 1999
Publisher:
Pharmaceutical Society of Japan
DOI：
10.1248/bpb.22.767
ISSN：
0918-6158
-
118(P58) Synthetic Study of (-)-Dysiherbaine, a New Marine Neurotoxic Amino Acid
Maeyama Junji, Kamada Kazuko, Iwabuchi Yoshiharu, Hatakeyama Susumi
Symposium on the Chemistry of Natural Products, symposium papers (40) 697-702 1998/08/31
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.40.0_697
-
Concise enantioselective synthesis of (+)-aspicilin based on a ruthenium catalyzed olefin metathesis reaction
T Nishioka, Y Iwabuchi, H Irie, S Hatakeyama
TETRAHEDRON LETTERS 39 (31) 5597-5600 1998/07
DOI：
10.1016/S0040-4039(98)01130-7
ISSN：
0040-4039
-
Evolving catalytic antibodies in a phage-displayed combinatorial library
Fujii, I, S Fukuyama, Y Iwabuchi, R Tanimura
NATURE BIOTECHNOLOGY 16 (5) 463-467 1998/05
DOI：
10.1038/nbt0598-463
ISSN：
1087-0156
-
Synthesis of viridiofungin A trimethyl ester and determination of the absolute structure of viridiofungin A
T Esumi, Y Iwabuchi, H Irie, S Hatakeyama
TETRAHEDRON LETTERS 39 (8) 877-880 1998/02
DOI：
10.1016/S0040-4039(97)10754-7
ISSN：
0040-4039
-
Preparation of 2-iodo-1,3-butadienes from 1-trimethylsilyl-2,3-butadienes and their functionalizations
T Nishiyama, T Esumi, Y Iwabuchi, H Irie, S Hatakeyama
TETRAHEDRON LETTERS 39 (1-2) 43-46 1998/01
DOI：
10.1016/S0040-4039(97)10413-0
ISSN：
0040-4039
-
A new stereoselective route to (-)-octalactin A based on intramolecular SmI2 promoted Reformatsky reaction
Susumu Inoue, Yoshiharu Iwabuchi, Hiroshi Irie, Susumi Hatakeyama
Synlett (7) 735-736 1998
Publisher:
Georg Thieme Verlag
DOI：
10.1055/s-1998-1778
ISSN：
0936-5214
-
A novel enantioselective synthesis of (+)-myriocin based on the chemistry of 1-trimethylsilylbuta-2,3-dienes
S Hatakeyama, M Yoshida, T Esumi, Y Iwabuchi, H Irie, T Kawamoto, H Yamada, M Nishizawa
TETRAHEDRON LETTERS 38 (45) 7887-7890 1997/11
DOI：
10.1016/S0040-4039(97)10077-6
ISSN：
0040-4039
-
Synthetic studies of vitamin D analogs .24. Convergent synthesis of 1 alpha,25-dihydroxy-2 beta-(3-hydroxypropoxy)vitamin D-3 (ED-71)
S Hatakeyama, T Ikeda, J Maeyama, T Esumi, Y Iwabuchi, H Irie, A Kawase, N Kubodera
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 7 (22) 2871-2874 1997/11
DOI：
10.1016/S0960-894X(97)10095-6
ISSN：
0960-894X
-
Enantioselective preparation of 1-benzyloxy-3-methyl-6-heptene-2,4-diols: Total synthesis of (+)-prelactone C
T Esumi, H Fukuyama, R Oribe, K Kawazoe, Y Iwabuchi, H Irie, S Hatakeyama
TETRAHEDRON LETTERS 38 (27) 4823-4826 1997/07
DOI：
10.1016/S0040-4039(97)01042-3
ISSN：
0040-4039
-
Reaction properties of immobilized catalytic antibodies that deprotect acylated carbohydrates
A Kondo, H Fukuda, Y Iwabuchi, Fujii, I
JOURNAL OF FERMENTATION AND BIOENGINEERING 82 (5) 452-457 1996
DOI：
10.1016/S0922-338X(97)86982-6
ISSN：
0922-338X
-
26 APPLICATION OF CATALYTIC ANTIBODIES FOR FACILE SYNTHESIS OF OLIGOSACCHARIDES
IWABUCHI Yoshiharu, SUGIHARA Yoshiaki, FUKUYAMA Shiro, FUJII Ikuo
Symposium on the Chemistry of Natural Products, symposium papers (37) 150-155 1995/09/01
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.37.0_150
-
Catalytic antibody and its medical applications
I. Fujii, Y. Iwabuchi
Nippon rinsho. Japanese journal of clinical medicine 53 518-527 1995/02/01
ISSN：
0047-1852
-
REGIOSELECTIVE AND STEREOSELECTIVE DEPROTECTION OF ACYLATED CARBOHYDRATES VIA CATALYTIC ANTIBODIES
Y IWABUCHI, H MIYASHITA, R TANIMURA, K KINOSHITA, M KIKUCHI, FUJII, I
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 116 (2) 771-772 1994/01
DOI：
10.1021/ja00081a049
ISSN：
0002-7863
-
26 Regio- and Stereoselective Hydrolysis of Ester Bond on Carbohydrate by Catalytic Antibody
Iwabuchi Y., Karaki Y., Miyashita H., Kinoshita K., Hara T., Tanimura R., Kikuchi M., Fujii I.
Symposium on the Chemistry of Natural Products, symposium papers (35) 194-201 1993/09/10
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.35.0_194
-
TOTAL SYNTHESIS OF CALICHEAMICIN-GAMMA-1(I) .1. SYNTHESIS OF THE OLIGOSACCHARIDE FRAGMENT
RD GRONEBERG, T MIYAZAKI, NA STYLIANIDES, TJ SCHULZE, W STAHL, EP SCHREINER, T SUZUKI, Y IWABUCHI, AL SMITH, KC NICOLAOU
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 115 (17) 7593-7611 1993/08
DOI：
10.1021/ja00070a004
ISSN：
0002-7863
-
X-Neu5Ac: A novel substrate for chromogenic assay of neuraminidase activity in bacterial expression systems
Ikuo Fujii, Yoshiharu Iwabuchi, Tadashi Teshima, Tetsuo Shiba, Masakazu Kikuchi
Bioorganic and Medicinal Chemistry 1 (2) 147-149 1993
DOI：
10.1016/S0968-0896(00)82112-4
ISSN：
0968-0896
-
TOTAL SYNTHESIS OF SIALYL DIMERIC LEX
KC NICOLAOU, CW HUMMEL, Y IWABUCHI
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 114 (8) 3126-3128 1992/04
DOI：
10.1021/ja00034a063
ISSN：
0002-7863
-
Total Synthesis of Calicheamicin–Dynemicin Hybrid Molecules
K. C. Nicolaou, Erwin P. Schreiner, Yoshiharu Iwabuchi, Toshio Suzuki
Angewandte Chemie International Edition in English 31 340-342 1992/01/01
DOI：
10.1002/anie.199203401
ISSN：
0570-0833
-
13 THE KATSUKI-SHARPLESS ASYMMETRIC EPOXIDATION OF ALKENYLETHYLENE GLYCOL AND ITS UTILIZATION FOR THE NATURAL PRODUCT SYNTHESIS
Takano S., Iwabuchi Y., Yoshimitsu T., Ogasawara K.
Symposium on the Chemistry of Natural Products, symposium papers (33) 94-100 1991/09/07
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.33.0_94
-
INVERSION OF DIASTEREOFACIAL AND ENANTIOFACIAL SELECTIVITIES IN THE KATSUKI-SHARPLESS ASYMMETRIC EPOXIDATION OF (E)-ALKENYLETHYLENE GLYCOLS
S TAKANO, Y IWABUCHI, K OGASAWARA
SYNLETT 1991 (8) 548-550 1991/08
DOI：
10.1055/s-1991-20791
ISSN：
0936-5214
-
THE KATSUKI-SHARPLESS ASYMMETRIC EPOXIDATION OF (E)-2,5-DIHYDROXY-2,5-DIMETHYL-3-HEXENE
S TAKANO, Y IWABUCHI, K OGASAWARA
TETRAHEDRON LETTERS 32 (29) 3527-3528 1991/07
DOI：
10.1016/0040-4039(91)80823-O
ISSN：
0040-4039
-
INVERSION OF ENANTIOSELECTIVITY IN THE KINETIC RESOLUTION MODE OF THE KATSUKI-SHARPLESS ASYMMETRIC EPOXIDATION REACTION
Yoshiharu Iwabuchi
Journal of the American Chemical Society 113 2786-2787 1991/01/01
DOI：
10.1021/JA00007A082
ISSN：
0002-7863
-
An enantio- and stereo-controlled synthesis of L-erythro- and D-threo-C18-sphingosines via the anomalous version of the katsuki-sharpless asymmetric epoxidation reaction
Seiichi Takano, Yoshiharu Iwabuchi, Kunio Ogasawara
Journal of the Chemical Society, Chemical Communications (12) 820-821 1991
DOI：
10.1039/C39910000820
ISSN：
0022-4936
-
43 ENANTIOCONTROLLED ROUTE TO SOME ISOPRENOID NATURAL PRODUCTS BY NEW CHIRAL α-ACETYLENE ALCOHOL SYNTHESIS
Takano S., Iwabuchi Y., Sugihara T., Samizu K., Shimazaki Y., Ogasawara K.
Symposium on the Chemistry of Natural Products, symposium papers (32) 320-327 1990/09/25
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.32.0_320
-
PRACTICAL ROUTE TO BOTH (S)-ENANTIOMER AND (R)-ENANTIOMER OF O-(4-METHOXYPHENYL)GLYCIDOL USING (S)-1,2-O-ISOPROPYLIDENEGLYCEROL AS A COMMON PRECURSOR
S TAKANO, M MORIYA, M SUZUKI, Y IWABUCHI, T SUGIHARA, K OGASAWARA
HETEROCYCLES 31 (8) 1555-1563 1990/08
DOI：
10.3987/COM-90-5476
ISSN：
0385-5414
-
A CHIRAL ROUTE TO BOTH ENANTIOMERS OF PHYSOSTIGMINE AND THE 1ST SYNTHESIS OF (-)-NORPHYSOSTIGMINE
Peer-reviewed
S TAKANO, M MORIYA, Y IWABUCHI, K OGASAWARA
CHEMISTRY LETTERS (1) 109-112 1990/01
ISSN：
0366-7022
eISSN：
1348-0715
-
A CONVERGENT ENANTIOCONTROLLED ROUTE TO MEVALONOLACTONE AND VITAMIN-E FROM (S)-O-BENZYLGLYCIDOL
S TAKANO, Y SHIMAZAKI, Y IWABUCHI, K OGASAWARA
TETRAHEDRON LETTERS 31 (25) 3619-3622 1990
DOI：
10.1016/S0040-4039(00)94459-9
ISSN：
0040-4039
-
AN ENANTIOCONVERGENT ROUTE TO (-)-ANISOMYCIN FROM BOTH (S)-ENANTIOMERS AND (R)-ENANTIOMERS OF EPICHLOROHYDRIN
S TAKANO, Y IWABUCHI, K OGASAWARA
HETEROCYCLES 29 (10) 1861-1864 1989/10
DOI：
10.3987/COM-89-5104
ISSN：
0385-5414
-
16 ENANTIOCONTROLLED SYNTHESIS OF NATURAL PRODUCTS UTILIZING BICYCLO[2.2.1]HEPTANE SYNTHONS
Takano S., Inomata K., Sato T., Samizu K., Sugihara T., Iwabuchi Y., Takahashi M., Ogasawara K.
Symposium on the Chemistry of Natural Products, symposium papers (31) 112-119 1989/09/17
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.31.0_112
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A CONCISE ENANTIOSELECTIVE SYNTHESIS OF ACROMELIC ACID-B FROM (S)-O-BENZYLGLYCIDOL
S TAKANO, S TOMITA, Y IWABUCHI, K OGASAWARA
HETEROCYCLES 29 (8) 1473-1476 1989/08
DOI：
10.3987/COM-89-5064
ISSN：
0385-5414
-
A CONVENIENT ONE-FLASK SYNTHESIS OF ALPHA-METHYLENEALDEHYDES FROM PRIMARY ALCOHOLS
Peer-reviewed
S TAKANO, K INOMATA, K SAMIZU, S TOMITA, M YANASE, M SUZUKI, Y IWABUCHI, T SUGIHARA, K OGASAWARA
CHEMISTRY LETTERS (7) 1283-1284 1989/07
ISSN：
0366-7022
eISSN：
1348-0715
-
A concise enantioselective synthesis of (+)-muscarine from (R)-O-benzylglycidol [(R)-benzyloxymethyloxirane]
Seiichi Takano, Yoshiharu Iwabuchi, Kunio Ogasawara
Journal of the Chemical Society, Chemical Communications (18) 1371-1372 1989
DOI：
10.1039/C39890001371
ISSN：
0022-4936
-
CONCISE SYNTHESIS OF C-2-SYMMETRIC TRANS-2,5-DIOXYMETHYLPYRROLIDINE DERIVATIVES BY NOVEL CYCLIZATION
S TAKANO, M MORIYA, Y IWABUCHI, K OGASAWARA
TETRAHEDRON LETTERS 30 (29) 3805-3806 1989
DOI：
10.1016/S0040-4039(01)80661-4
ISSN：
0040-4039
-
CONCISE STEREOSELECTIVE SYNTHESIS OF (2S,4R)-4-HYDROXYPROLINE FROM (S)-O-BENZYLGLYCIDOL BY A NOVEL CYCLIZATION
S TAKANO, Y IWABUCHI, K OGASAWARA
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS (23) 1527-1528 1988/12
DOI：
10.1039/C39880001527
ISSN：
0022-4936
-
CONFIGURATIONAL CORRELATIONS OF SOME SECONDARY ALCOHOLS BY H-1-NMR SPECTROSCOPY
Yoshiharu Iwabuchi
Chemistry Letters 1988
DOI：
10.1246/CL.1988.1827
-
A concise enantioselective route to (-)-kainic acid from (S)-2-(benzyloxymethyl)oxirane
Seiichi Takano, Yoshiharu Iwabuchi, Kunio Ogasawara
Journal of the Chemical Society, Chemical Communications (17) 1204-1206 1988
DOI：
10.1039/C39880001204
ISSN：
0022-4936
-
A CONCISE ENANTIOSELECTIVE SYNTHESIS OF ACROMELIC ACID-A
S TAKANO, Y IWABUCHI, K OGASAWARA
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 109 (18) 5523-5524 1987/09
DOI：
10.1021/ja00252a037
ISSN：
0002-7863
-
11 CHIRAL ROUTES TO THE KAINOID AMINO ACIDS
Takano Seiichi, Sugihara Takumichi, Iwabuchi Yoshiharu, Satoh Shigeki, Ogasawara Kunio
Symposium on the Chemistry of Natural Products, symposium papers (29) 79-86 1987/07/25
Publisher:
Symposium on the chemistry of natural products
DOI：
10.24496/tennenyuki.29.0_79
-
A Convenient Synthesis of 2-Cyclopentenone
Seiichi Takano, Yoshiharu Iwabuchi, Michiyasu Takahashi, Kunio Ogasawara
Chemical and Pharmaceutical Bulletin 34 (8) 3445-3446 1986
DOI：
10.1248/cpb.34.3445
ISSN：
1347-5223 0009-2363
