Details of the Researcher

PHOTO

Kosuke Kuwabara
Section
Graduate School of Agricultural Science
Job title
Specially Appointed Assistant Professor(Research)

Research History 4

  • 2024/04 - Present
    東北大学大学院農学研究科

  • 2021/04 - 2024/03
    Japan Society for the Promotion of Science

  • 2021/04 - 2024/03
    筑波大学大学院 理工情報生命学術院　博士後期課程

  • 2019/04 - 2021/03
    筑波大学大学院 生命環境科学研究科　博士前期課程

Education 4

  • University of Tsukuba

    2021/04 - 2024/03

  • University of Tsukuba　Graduate School of Life and Environmental Sciences

    2019/04 - 2021/03

  • University of Tsukuba　School of Life and Environmental Sciences, College of Biological Sciences

    2017/04 - 2019/03

  • National Institute of Technology, Numazu College　Chemistry and Biochemistry

    2012/04 - 2017/03

Professional Memberships 3

  • Japanese Society of Breeding

    2021 - Present

  • 日本植物生理学会

    2022/04 -

  • 日本植物バイオテクノロジー学会

    2022/04 -

Research Interests 8

  • こめ油

  • Fertility restoration

  • Rice

  • genome editing

  • pollen

  • mitochondria

  • cytoplasmic male sterility

  • tomato

Research Areas 3

  • Environmental science/Agricultural science / Plant genetics and breeding / pollen

  • Environmental science/Agricultural science / Plant genetics and breeding / mitochondria

  • Environmental science/Agricultural science / Plant genetics and breeding / cytoplasmic male sterility

Awards 8

  1. 第148回講演会 日本育種学会 優秀発表賞

    2025/09　日本育種学会　効率的なトマトF1種子生産を目指した稔性回復系統の開発と稔性回復機構の解明

  2. 優秀ポスター賞

    2024/11　第19回東北育種研究集会　組織別トランスクリプトーム解析による、イネのぬか特異的な遺伝子発現を誘導するcis-elementの探索

  3. The JSPB Student Award

    2024/08　Japanese Society for Plant Biotechnology　Studies on cytoplasmic male sterility and fertility restoration in tomato

  4. Best Posters Presentations

    2022/11　The XVII International Conference on the Plant Family of Solanaceae (SOL2022)　Transcriptome analysis in cytoplasmic male sterile tomato to elucidate male sterile mechanism

  5. 優秀発表賞

    2022/10　第5回 植物インフォマティクス研究会・年会（2022年）　ミトコンドリアゲノム解析およびゲノム編集によるトマト細胞質雄性不稔遺伝子の同定

  6. Chairperson of Department commendation

    2021/03　Elucidation of molecular mechanism of male sterility in cytoplasmic male sterile tomato

  7. Excellent presentation award

    2021/03　Japanese Society of Breeding　Cytoplasmic male sterile tomato show morphological abnormality specifically during pollen germination

  8. 先導的研究者体験プログラム研究発表会 優秀賞

    2018/01　筑波大学　単為結果性を誘導した高品質トマトの開発

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Papers 9

  1. Relationship Between Open Reading Frame 320, a Gene Causing Male Sterility in Tomatoes, and Cytoplasmic Male Sterility in Potatoes Peer-reviewed

    Rika Nakajima, Rena Sanetomo, Kenta Shirasawa, Tohru Ariizumi, Kosuke Kuwabara

    Plant and Cell Physiology　2025/11/25

    Publisher: Oxford University Press (OUP)

    DOI： 10.1093/pcp/pcaf157 　

    ISSN： 0032-0781

    eISSN： 1471-9053

    More details Close

    Abstract Cytoplasmic male sterility (CMS) is a trait wherein plants cannot develop normal male organs because of mitochondrial genes. In potatoes (Solanum tuberosum), reports on the relevant mitochondrial genes remain scarce. Many potato cultivars express pollen sterility caused by mitochondria, thereby limiting their use as male parents in breeding. Therefore, identifying the causal genes is crucial for potato breeding. In this study, we focused on the T/β cytoplasm type, the most prevalent cytoplasm of potato worldwide, to explore mitochondrial genes involved in CMS in potatoes. We identified a novel gene, open reading frame 320 (orf320) from potato with T/β type cytoplasm by comparing the mitochondrial genomes. The accumulation level of orf320 transcripts was drastically reduced in the anthers of a fertile potato cultivar compared with those of a sterile cultivar. Functional analysis of tomatoes showed that overexpression of orf320 with a mitochondrial transit peptide induced male sterility phenotype accompanying abnormal anther development and pollen abortion. Furthermore, an investigation of orf320 in 124 potato cultivars revealed that this gene is tightly associated with the T/β type cytoplasm and is absent from cultivars with other cytoplasm types. These findings provide evidence that orf320 is a candidate CMS-causing gene in male sterility of T/β type cytoplasm, offering valuable insights for future potato breeding.

  2. Artificial Mutations in the Nuclear Gene Encoding Mitochondrial RNA Polymerase Restore Pollen Fertility in Cytoplasmic Male Sterile Tomato Peer-reviewed

    Kosuke Kuwabara, Rika Nakajima, Van Bosstraeten Alexis Gaetan, Kentaro Ezura, Kinya Toriyama, Tohru Ariizumi, Kenta Shirasawa

    Plant Biotechnology Journal　2025/10/23

    Publisher: Wiley

    DOI： 10.1111/pbi.70417 　

    ISSN： 1467-7644

    eISSN： 1467-7652

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    ABSTRACT Cytoplasmic male sterility (CMS) and restorer of fertility ( Rf ) are important traits in F 1 hybrid breeding. However, the CMS/ Rf system has not been used in tomatoes because of the limited resources of Rf lines. In this study, we performed mutagenesis in tomato CMS seeds and successfully obtained 13 suppressor mutants with pollen fertility. Using bulked segregant analysis and whole‐genome sequencing for each suppressor mutant, we detected mutations associated with fertility restoration in the nuclear‐encoded gene for the mitochondrial RNA polymerase termed SlRPOTm in four independent mutants created through mutagenesis. Furthermore, we found that the loss of function of SlRPOTm was associated with fertility restoration in the tomato CMS line. Expression analysis of orf137 , a tomato CMS‐causing gene, revealed that reduced expression of orf137 was associated with fertility restoration in tomato CMS. In addition, F 1 plants carrying mutations in SlRPOTm were generated, and tomato fruit formation was comparable to that of normal F 1 plants. This study demonstrates for the first time that the loss of function of mitochondrial RNA polymerase contributes to fertility restoration in CMS lines. Furthermore, it is possible to replace various tomato varieties with Rf lines using genome editing technology, which will promote tomato F 1 breeding in the future.

  3. Fertility restoration in cytoplasmic male sterile tomato via knockout of organelle DNA replication genes DNA polymerase I or Topoisomerase I

    Kosuke Kuwabara, Van Bosstraeten Alexis Gaetan, Rika Nakajima, Kentaro Ezura, Kinya Toriyama, Kenta Shirasawa, Tohru Ariizumi

    SSRN　2025/10/19

    Publisher: Elsevier BV

    DOI： 10.2139/ssrn.5625869 　

  4. Characterization and Transcriptome Analysis Reveal Abnormal Pollen Germination in Cytoplasmic Male Sterile Tomato Peer-reviewed

    Kosuke Kuwabara, Tohru Ariizumi

    International Journal of Molecular Sciences　26　(17)　8337-8337　2025/08/28

    Publisher: MDPI AG

    DOI： 10.3390/ijms26178337 　

    eISSN： 1422-0067

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    Cytoplasmic male sterility (CMS) is a plant trait wherein plants cannot develop normal male organs because of the mitochondrial genes. Although the mitochondrial gene orf137 has been identified as the CMS-causing gene in tomatoes, its function remains unclear. In this study, we characterized the sterile male phenotypes and analyzed the CMS pollen transcriptome. Microscopic and calcium imaging analyses revealed that CMS pollen exhibited abnormal germination from multiple apertures, accompanied by elevated calcium concentrations and vesicle accumulation, which are typically observed in pollen tube tips. RNA-Seq analysis revealed 440 differentially expressed genes, including four pectin methylesterase inhibitor (PMEI) genes that were highly expressed in the pollen. PME activity was significantly reduced in CMS pollen, suggesting its association with abnormal pollen germination. ATP and reactive oxygen species (ROS) levels, which are key mediators of mitochondrial retrograde signaling (MRS), remained unchanged in CMS pollen, and the expression of the mitochondrial stress marker AOX1a was not elevated. These findings suggest that orf137 triggers an alternative MRS pathway independent of ATP or ROS, potentially leading to PMEI upregulation and abnormal pollen germination. Our results reveal a previously unrecognized mechanism of CMS-induced male sterility in tomatoes involving nuclear gene regulation through unconventional mitochondrial signaling.

  5. Multiple fertility restorer loci for cytoplasmic male sterility caused by orf137 in tomato Peer-reviewed

    Yurie Iki, Issei Harada, Kentaro Ezura, Seira Mashita, Kosuke Kuwabara, Hitomi Takei, Atsushi Toyoda, Kenta Shirasawa, Tohru Ariizumi

    Journal of Experimental Botany　2025/07/08

    Publisher: Oxford University Press (OUP)

    DOI： 10.1093/jxb/eraf309 　

    ISSN： 0022-0957

    eISSN： 1460-2431

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    Abstract Cytoplasmic male sterility (CMS) in plants is caused by incompatibility between nuclear and cytoplasmic genetic information. Fertility can be restored through the action of fertility restoration (RF) genes, which are usually present in the nucleus. CMS lines of tomato (Solanum lycopersicum) have been developed from asymmetric cell fusions, in these lines, cultivated tomato served as a nuclear donor and its wild relative, S. acaule, as a cytoplasm donor. Although RF genes are present in wild relatives of tomato, no genetic or genomic information on the RF genes is yet available. This study reports an RF genetic locus, RF1, on chromosome 1 of S. pimpinellifolium LA1670 and S. lycopersicum var. cerasiforme LA1673 that was revealed by bulked segregant analysis and sequencing. An additional RF locus, RF2, was identified on chromosome 2 of LA1670. The genomic sequence of S. cheesmaniae LA0166 was assembled using high-fidelity, long-read sequencing technology. Sequence comparisons identified further candidate RF genes on chromosome 1 of S. cheesmaniae LA0166. These results suggested that multiple gene loci control the fertility restoration trait in wild relatives of tomato.

  6. Prospects for organelle genome breeding

    Kosuke Kuwabara, Mai Tsujimura, Issei Nakazato, Nobuhiro Tsutsumi, Mizuki Takenaka, Tomohiko Kazama

    Breeding Research　2024/04

    Publisher: Japanese Society of Breeding

    DOI： 10.1270/jsbbr.26.w02 　

    ISSN： 1344-7629

    eISSN： 1348-1290

  7. orf137 triggers cytoplasmic male sterility in tomato International-journal Peer-reviewed

    Kosuke Kuwabara, Shin-ichi Arimura, Kenta Shirasawa, Tohru Ariizumi

    Plant Physiology　189　(2)　465-468　2022/02/25

    Publisher: Oxford University Press (OUP)

    DOI： 10.1093/plphys/kiac082 　

    eISSN： 1532-2548

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    mitoTALEN, a mitochondrial genome editing technology, demonstrated that the mitochondrial gene orf137 is responsible for inducing cytoplasmic male sterility in tomato.

  8. Organelle genome assembly uncovers the dynamic genome reorganization and cytoplasmic male sterility associated genes in tomato International-journal Peer-reviewed

    Kosuke Kuwabara, Issei Harada, Yuma Matsuzawa, Tohru Ariizumi, Kenta Shirasawa

    Horticulture Research　8　(1)　250-250　2021/12

    Publisher: Oxford University Press (OUP)

    DOI： 10.1038/s41438-021-00676-y 　

    ISSN： 2662-6810

    eISSN： 2052-7276

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    Abstract To identify cytoplasmic male sterility (CMS)-associated genes in tomato, we determined the genome sequences of mitochondria and chloroplasts in three CMS tomato lines derived from independent asymmetric cell fusions, their nuclear and cytoplasmic donors, and male fertile weedy cultivated tomato and wild relatives. The structures of the CMS mitochondrial genomes were highly divergent from those of the nuclear and cytoplasmic donors, and genes of the donors were mixed up in these genomes. On the other hand, the structures of CMS chloroplast genomes were moderately conserved across the donors, but CMS chloroplast genes were unexpectedly likely derived from the nuclear donors. Comparative analysis of the structures and contents of organelle genes and transcriptome analysis identified three genes that were uniquely present in the CMS lines, but not in the donor or fertile lines. RNA-sequencing analysis indicated that these three genes transcriptionally expressed in anther, and identified different RNA editing levels in one gene, orf265, that was partially similar to ATP synthase subunit 8, between fertile and sterile lines. The orf265 was a highly potential candidate for CMS-associated gene. This study suggests that organelle reorganization mechanisms after cell fusion events differ between mitochondria and chloroplasts, and provides insight into the development of new F1 hybrid breeding programs employing the CMS system in tomato.

  9. De novo genome assembly of two tomato ancestors, Solanum pimpinellifolium and Solanum   lycopersicum var. cerasiforme, by long-read sequencing Peer-reviewed

    Hitomi Takei, Kenta Shirasawa, Kosuke Kuwabara, Atsushi Toyoda, Yuma Matsuzawa, Shinji Iioka, Tohru Ariizumi

    DNA Research　28　(1)　2021/01/19

    Publisher: Oxford University Press ({OUP})

    DOI： 10.1093/dnares/dsaa029 　

    ISSN： 1756-1663

    eISSN： 1756-1663

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    Abstract The ancestral tomato species are known to possess genes that are valuable for improving traits in breeding. Here, we aimed to construct high-quality de novo genome assemblies of Solanum pimpinellifolium ‘LA1670’ and S. lycopersicum var. cerasiforme ‘LA1673’, originating from Peru. The Pacific Biosciences (PacBio) long-read sequences with 110× and 104× coverages were assembled and polished to generate 244 and 202 contigs spanning 808.8 Mbp for ‘LA1670’ and 804.5 Mbp for ‘LA1673’, respectively. After chromosome-level scaffolding with reference guiding, 14 scaffold sequences corresponding to 12 tomato chromosomes and 2 unassigned sequences were constructed. High-quality genome assemblies were confirmed using the Benchmarking Universal Single-Copy Orthologs and long terminal repeat assembly index. The protein-coding sequences were then predicted, and their transcriptomes were confirmed. The de novo assembled genomes of S. pimpinellifolium and S. lycopersicum var. cerasiforme were predicted to have 71,945 and 75,230 protein-coding genes, including 29,629 and 29,185 non-redundant genes, respectively, as supported by the transcriptome analysis results. The chromosome-level genome assemblies coupled with transcriptome data sets of the two accessions would be valuable for gaining insights into tomato domestication and understanding genome-scale breeding.

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Misc. 8

  1. Overexpression of orf320 causes male sterility in tomato

    中嶋梨花, 桑原康介, 白澤健太, 有泉亨

    日本植物生理学会年会(Web)　65th　2024

  2. Engineering tomato fertility restoration lines by mutagenesis and identification of fertility restoration genes

    桑原康介, 中嶋梨花, VAN BOSSTRAETEN A., 江面健太郎, 江面健太郎, 鳥山欽哉, 有泉亨, 白澤健太

    育種学研究　26　2024

    ISSN： 1344-7629

  3. Research to restore fertility in CMS potato varieties

    中嶋梨花, 桑原康介, 有泉亨, 有村慎一, 白澤健太

    育種学研究　25　2023

    ISSN： 1344-7629

  4. Histological evaluation of fertility restoration lines against cytoplasmic male sterile tomato

    眞下星来, 白澤健太, 武井瞳, 原田壱成, 壹岐友里恵, 桑原康介, 鈴木秀之, 飯岡真司, 有泉亨

    育種学研究　25　2023

    ISSN： 1344-7629

  5. Search for CMS-causing genes in tomato and potato

    桑原康介, 中嶋梨花, 小達夏輝, 有村慎一, 白澤健太, 有泉亨

    育種学研究　25　2023

    ISSN： 1344-7629

  6. Genome assemblies of two wild tomatoes

    武井瞳, 白澤健太, 桑原康介, 豊田敦, 松澤佑馬, 飯岡真司, 有泉亨

    育種学研究　23　2021

    ISSN： 1344-7629

  7. Comparative analysis of organella genome structures in interspecific hybrid tomato lines generated by asymmetric cell fusion

    白澤健太, 桑原康介, 原田壱成, 武井瞳, 壹岐友里恵, VANN Sockmean, 松澤佑馬, 飯岡真司, 有泉亨

    育種学研究　22　2020

    ISSN： 1344-7629

  8. de novo genome assembly of two wild tomatoes

    武井瞳, 白澤健太, 桑原康介, 松澤佑馬, 飯岡真司, 有泉亨

    育種学研究　22　2020

    ISSN： 1344-7629

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Books and Other Publications 1

  1. Breeding by modification of chloroplast and mitochondrial genomes

    Kuwabara Kosuke

    2024/11

Presentations 35

  1. Loss-of-function in mitochondrial RNA polymerase restores pollen fertility in cytoplasmic male sterile tomato

    Kuwabara K., Nakajima R., Van Bosstraeten A., Ezura K., Toriyama K., Ariizumi T., Shirasawa K.

    2025/12/03

  2. こめ油増産に向けたリパーゼ遺伝子のプロモーターおよびコード領域変異株の作出と解析

    桑原康介, 浦川めぐみ, 鳥山欽哉, 伊藤幸博

    日本育種学会第148回講演会　2025/09/11

  3. Development of restorer of fertility lines and elucidation of fertility restoration mechanisms toward efficient F₁ seed production in tomato

    Kosuke Kuwabara, Rika Nakajima, Alexis Van Bosstraeten, Kentaro Ezura, Kinya, Toriyama, Tohru Arizumi, Kenta Shirasawa

    2025/09/11

  4. こめ油増産を目指した米ぬか特異的 cis-element の探索とリパーゼ遺伝子プロモーターのゲノム編集

    桑原康介, 浦川めぐみ, 伊藤幸博, 鳥山欽哉

    イネ遺伝学・分子生物学ワークショップ 2025　2025/07/12

  5. Development of Fertility Restored Tomatoes by Mutagenesis

    Kosuke Kuwabara

    2025/05/13

  6. 未熟種子での一過的発現によるイネリパーゼ遺伝子のぬか層特異的シス配列の探索

    浦川 めぐみ, 桑原 康介, 鳥山 欽哉, 伊藤 幸博

    日本育種学会 第147回講演会　2025/03/21

  7. イネのぬか特異的な遺伝子発現を誘導する cis-element の同定を目指したメタ解析

    桑原 康介, 浦川 めぐみ, 伊藤 幸博, 鳥山 欽哉

    日本育種学会 第147回講演会　2025/03/21

  8. Engineering tomato fertility restoration lines by mutagenesis and identi)cation of fertility restoration genes

    Kosuke Kuwabar, Rika Nakajim, Alexis Van Bosstraete, Kentaro Ezura, Kinya Toriyama, Tohru Arizumi, Kenta Shirasaw

    2024/09/20

  9. Studies on cytoplasmic male sterility and fertility restoration in tomato Invited

    Kosuke Kuwabara

    The 41st Annual Meeting of the Japanese Society for Plant Biotechnology (Sendai)　2024/08/31

  10. トマトの細胞質雄性不稔性原因遺伝子と稔性回復遺伝子の探索

    桑原康介, 中嶋梨花, ヴァンボストラエテンアレクシス, 江面健太, 鳥山欽哉, 有村慎一, 白澤健

    学術変革領域研究(A) 細胞内共生オルガネラのゲノム制御 若手の会　2024/07/22

  11. Overexpression of potato orf320 causes male sterility in tomato

    Rika Nakajima, Kosuke Kuwabara, Kenta Shirasawa, Tohru Ariizumi

    13th International Conference for Plant Mitochondrial Biology (ICPMB 2024)

  12. Overexpression of orf320 causes male sterility in tomato.

    Nakajima Rika, Kuwabara Kosuke, Shirasawa Kenta, Ariizumi Tohru

    65th Annual Meeting of JSPP (jspp2024)　2024/03/18

  13. Search for genes related to pollen germination by transcriptome analysis in cytoplasmic male sterile tomato

    Kuwabara Kosuke, Ariizumi Tohru

    2024/03/17

  14. トマトとジャガイモにおける細胞質雄性不稔性に関する研究 Invited

    桑原 康介, 中嶋 梨花, 有村 慎一, 白澤 健太, 有泉 亨

    「植物科学の成果を品種改良に活かす」研究集会　2024/02/01

  15. 細胞質雄性不稔性トマトに対する稔性回復系統の組織学的評価

    眞下星来,白澤健太, 武井瞳,原田壱成,壹岐友里恵,桑原康介, 鈴木秀之, 飯岡真司, 有泉亨

    第144回日本育種学会　2023/09/17

  16. 細胞質雄性不稔性ジャガイモ品種の稔性回復に向けた研究

    中嶋梨花, 桑原康介, 有泉亨, 有村慎一, 白澤健太

    第144回日本育種学会　2023/09/17

  17. トマトおよびジャガイモにおけるCMS原因遺伝子の探索 Invited

    桑原康介, 中嶋梨花, 小達夏輝, 有村慎一, 白澤健太, 有泉亨

    第144回日本育種学会　2023/09/16

  18. Pollen from cytoplasmic male sterile tomato show triple-germination

    Kosuke Kuwabara, Tohru Ariizumi

    Plant Biology 2023　2023/08/05

  19. Research to restore fertility in CMS potato varieties

    Nakajima Rika, Kuwabara Kosuke, Ariizumi Thoru

    Plant Biology 2023　2023/08/05

  20. Discovery of Candidate Genes for Potato β-CMS

    Rika Nakajima, Kosuke Kuwabara, Natsuki Odate, Kenta Shirasawa, Tohru Ariizumi

    The 64th Annual Meeting of the Japanese Society of Plant Physiologists　2023/03/15

  21. Investigation of Ca2+ and vesicle localization inside pollen of cytoplasmic male sterile tomato

    Kosuke Kuwabara, Tohru Ariizumi

    The 64th Annual Meeting of the Japanese Society of Plant Physiologists (JSPP2023)　2023/03/15

  22. A novel mitochondrial gene, orf137, triggers cytoplasmic male sterility in tomato

    Kosuke KUWABARA

    14th HOPE MEETING with Nobel Laureates　2023/02/28

  23. Transcriptome analysis in cytoplasmic male sterile tomato to elucidate male sterile mechanism

    Kosuke Kuwabara, Tohru Ariizumi

    The XVII International Conference on the Plant Family of Solanaceae (SOL2022)　2022/11/01

  24. ミトコンドリアゲノム解析およびゲノム編集によるトマト細胞質雄性不稔遺伝子の同定

    桑原康介, 有村慎一, 白澤健太, 有泉亨

    植物インフォマティクス研究会・年会 (第5回)　2022/10/18

  25. Identification of causative gene for cytoplasmic male sterility in tomato Invited

    Kosuke Kuwabara, Shin-ichi Arimura, Kenta Shirasawa, Tohru Ariizumi

    Japan Solanaceae Consortium Symposium (JSOL2022)　2022/10/09

  26. 細胞質雄性不稔性トマトにおける花粉内部 Ca2+イメージング

    桑原康介, 有泉亨

    日本育種学会 (第142回講演会)　2022/09/24

  27. ミトコンドリアゲノム編集によるトマト細胞質雄性不稔性原因遺伝子の同定

    桑原康介, 有村慎一, 白澤健太, 有泉亨

    日本植物バイオテクノロジー学会 (第39回)　2022/09/13

  28. 新規ミトコンドリア遺伝子orf137はトマト細胞質雄性不稔性を引き起こす

    桑原康介, 有村慎一, 白澤健太, 有泉亨

    日本育種学会 (第141回講演会)　2022/03/21

  29. Characterization of cytoplasmic male sterile tomato to elucidate male sterile mechanism

    Kosuke Kuwabara, Issei Harada, Yuma Matsuzawa, Shinji Iioka, Kenta Shirasawa, Tohru Ariizumi

    Japan Solanaceae Consortium (17th JSOL 2021)　2021/11/26

  30. 細胞質雄性不稔性トマトは花粉発芽時特異的に形態異常を示す

    桑原康介, 原田壱成, 松澤佑馬, 飯岡真司, 白澤健太, 有泉亨

    日本育種学会 (第139回講演会)　2021/03/20

  31. Comparative analysis of organelle genome structures in interspecific hybrid tomato lines generated by asymmetric cell fusion

  32. 野生種トマトS.pimpinellifolium とS.lycopersicum var. cerasiformeのゲノムアセンブリ

    武井瞳, 白澤健太, 桑原康介, 松澤佑馬, 飯岡真司, 有泉亨

    The 16th Japanese Solanaceae Conference (JSOL2019)

  33. Attempt of S. pimpinellifolium reference genome construction by de novo assembly

    Hitomi Takei, Kenta Shirasawa, Kosuke Kuwabara, Yuma Matsuzawa, Shinji Iioka, Tohru Ariizumi

    The XVI Solanaceae Conference (SOL 2019)

  34. 一過的発現によるイネリパーゼ遺伝子のぬか層特異的シス配列の探索―こめ油増産を目指した育種基盤整備―

    浦川めぐみ, 桑原康介, 鳥山欽哉, 伊藤幸博

    第19回東北育種研究集会　2024/11/30

  35. 組織別トランスクリプトーム解析による、イネのぬか特異的な遺伝子発現を誘導するcis-elementの探索

    桑原康介, 浦川めぐみ, 伊藤幸博, 鳥山欽哉

    第19回東北育種研究集会　2024/11/30

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Industrial Property Rights 4

  1. 細胞質雄性不稔性遺伝子、雄性不稔性植物及びその種子

    有泉亨, 桑原康介, 中嶋梨花

    Property Type: Patent

  2. ナス科の雄性稔性回復植物、ナス科植物の雄性稔性回復方法、ナス科の雄性稔性回復植物の製造方法及びナス科植物の雄性稔性回復判別方法

    有泉亨, 桑原康介, 眞下星来, 壹岐友里恵, 武井瞳, 原田壱成, 江面健太郎, 白澤健太

    Property Type: Patent

  3. ナス科の雄性稔性回復植物、ナス科植物の雄性稔性回復方法、ナス科の雄性稔性回復植物の製造方法及びナス科植物の雄性稔性回復判別方法

    有泉亨, 桑原康介, ヴァンボストラエテンアレクシスガエタン, 白澤健太

    Property Type: Patent

  4. 細胞質雄性不稔性遺伝子、雄性不稔回復植物、ナス科植物の細胞質雄性不稔の稔性を回復する方法、雄性不稔回復植物の製造方法、雄性不稔性植物、及び雄性不稔性植物の製造方法

    有泉亨, 桑原康介, 白澤健太, 有村慎一

    特許2023-32890

    Property Type: Patent

Research Projects 3

  1. 葯が欠損する細胞質雄性不稔性トマトの機構解明と実用化に向けた基盤構築

    桑原 康介

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究

    Institution: 東北大学

    2025/04/01 - 2028/03/31

  2. RNAプルダウンアッセイを活用した、育種に重要な稔性回復遺伝子の探索手法の確立と応用

    桑原康介

    Offer Organization: 公益財団法人日本科学協会

    System: 笹川科学研究助成

    2025/04 - 2026/02

  3. Elucidation of the molecular mechanism of male sterile and fertile recovery in cytoplasmic male sterile tomato

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research Grant-in-Aid for JSPS Fellows

    Category: Grant-in-Aid for JSPS Fellows

    Institution: University of Tsukuba

    2021/04 - 2024/03