Details of the Researcher

PHOTO

Hidenori Watanabe
Section
Graduate School of Life Sciences
Job title
Specially Appointed Senior Assistant Professor(Research)
e-Rad No.
00407686

Research History 9

  • 2024/10 - Present
    Tohoku University　Graduate School of Life Sciences　Project lecturer

  • 2024/04 - Present
    Tohoku University　Tohoku University School of Medicine, Department of Physiology　Part-time lecturer

  • 2015/04 - 2024/03
    Tohoku University　Graduate School of Medicine, Department of Physiology　Assistant Professor

  • 2019/03 - 2020/12
    The University of Chicago　Organismal Biology and Anatomy　Visiting Scholar

  • 2008/07 - 2015/03
    National Institute for Physiological Sciences　Department of Developmental Physiology　Postdoctoral Research Associate

  • 2007/04 - 2008/06
    Tamagawa University　Brain Science Institute　Research Fellow

  • 2005/04 - 2007/03
    Tamagawa University　Research Institute　Research Associate

  • 2003/04 - 2005/03
    Japan Society for the Promotion of Science　Research Fellowship for Young Scientists

  • 2002/04 - 2003/03
    Tamagawa University　Research Institute　Research Fellow

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Education 1

  • The University of Tokyo　School of Engineering　Department of Quantum Engineering and Systems Science

    1997/04 - 2002/03

Committee Memberships 7

  • 日本生理学会　第99回日本生理学会大会・組織委員会

    2021/04 - 2022/03

  • The 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society　セッション座長

    2014/08 - 2014/08

  • 計測自動制御学会システム・情報部門　自律分散システム部会 運営委員

    2013/04 - 2014/03

  • NIPS Mini-Workshop: Neural Decoding and Brain-Computer Interfaces　運営委員

    2013/07 - 2013/07

  • 生理研研究会: 生体-機械協調システム研究の進展　運営委員

    2013/06 - 2013/06

  • 第66回情報処理学会全国大会　セッション座長

    2004/03 - 2004/03

  • 電子情報通信学会ニューロコンピューティング研究会　セッション座長

    2004/03 - 2004/03

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Professional Memberships 3

  • IEEE

  • 北米神経科学会

  • 日本神経科学会

Research Interests 30

  • Machine Learning

  • Affect

  • Transformer

  • Chronic multichannel neural recordings

  • 筋電図

  • 包括脳ネットワーク

  • 脳プロ

  • パッチクランプ

  • BMI

  • 多次元生体情報記録

  • モーションキャプチャ

  • ECoG

  • マルチユニット記録

  • オプトジェネティックス

  • 位相同期

  • 脳波

  • ニューラルネットワーク

  • シナプス可塑性

  • 記憶

  • 随意運動

  • 高次脳機能

  • 樹状突起

  • 体性感覚野

  • 海馬

  • 運動野

  • 大脳皮質

  • ラット

  • 霊長類

  • 情報工学

  • 神経科学

Research Areas 2

  • Life sciences / Basic brain sciences /

  • Life sciences / Neuroscience - general /

Awards 1

  1. ビクトリノックス脳科学賞

    2015/11　リバネス　手指随意運動中における大脳皮質運動野浅層-深層の神経活動，並びに筋電位と動作の関係解明

Papers 26

  1. Machine learning-based decoding of emotional valence from electrophysiological signals in the monkey brain

    Shinya Nakamura, Tuo Xiaoying, Hidenori Watanabe, Takuya Sasaki, Kenichiro Tsutsui

    2026/05/18

    DOI： 10.64898/2026.05.13.724152 　

  2. Delta gamma oscillatory interactions support visuomotor processing in the lateral frontal cortex of macaque monkeys Peer-reviewed

    Sosuke Harigae, Hidenori Watanabe, Masashi Aoki, Hajime Mushiake

    Scientific Reports　2026/01/21

    DOI： 10.1038/s41598-026-36628-6 　

    ISSN： 2045-2322

  3. Theta Dynamics Contribute to Retrieving Motor Plans after Interruptions in the Primate Premotor Area Peer-reviewed

    Ryosuke Hosaka, Hidenori Watanabe, Toshi Nakajima, Hajime Mushiake

    Cerebral Cortex Communications　2　(4)　2021/10/01

    Publisher: Oxford University Press (OUP)

    DOI： 10.1093/texcom/tgab059 　

    ISSN： 2632-7376

    eISSN： 2632-7376

    More details Close

    Abstract To achieve a behavioral goal, we often need to maintain an internal action plan against external interruption and thereafter retrieve the action plan. We recently found that the maintenance and updating of motor plans are reflected by reciprocal changes in the beta and gamma power of the local field potential (LFP) of the primate medial motor areas. In particular, the maintenance of the immediate motor plan is supported by enhanced beta oscillations. However, it is unclear how the brain manages to maintain and retrieve the internal action plan against interruptions. Here, we show that dynamic theta changes contribute to the maintenance of the action plan. Specifically, the power of the theta frequency band (4–10 Hz) of LFPs increased before and during the interruption in the dorsal premotor areas in two monkeys. Without theta enhancement before the interruption, retrieval of the internal action plan was impaired. Theta and beta oscillations showed distinct changes depending on the behavioral context. Our results demonstrate that immediate and suspended motor plans are supported by the beta and theta oscillatory components of LFPs. Motor cortical theta oscillations may contribute to bridging motor plans across behavioral interruptions in a prospective manner.

  4. Forelimb movements evoked by optogenetic stimulation of the macaque motor cortex Peer-reviewed

    Hidenori Watanabe, Hiromi Sano, Satomi Chiken, Kenta Kobayashi, Yuko Fukata, Masaki Fukata, Hajime Mushiake, Atsushi Nambu

    Nature Communications　11　(1)　2020/12

    Publisher: Springer Science and Business Media LLC

    DOI： 10.1038/s41467-020-16883-5 　

    eISSN： 2041-1723

  5. Engineering approach for functional recovery based on body image adjustment by using biofeedback of electrical stimulation Peer-reviewed

    Hiroshi Yokoi, Yuki Sato, Minako Suzuki, Yoshiko Yabuki, Tatsuhiro Nakamura, Takashi Mori, Soichiro Morishita, Ryu Kato, Osamu Yamamura, Masafumi Kubota, Tomoko Kamisawa, Chiaki Igarashi, Tadashi Isa, Tatsuya Umeda, Hidenori Watanabe, Yukio Nishimura, Katsunori Ikoma, Tamaki Miyamoto

    Clinical Systems Neuroscience　203-247　2015/01/01

    Publisher: Springer Japan

    DOI： 10.1007/978-4-431-55037-2_12 　

  6. Phase locking of beta oscillation in electrocorticography (ECoG) in the monkey motor cortex at the onset of EMGs and 3D reaching movements Peer-reviewed

    Hidenori Watanabe, Kazutaka Takahashi, Tadashi Isa

    2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)　2015　55-58　2015

    DOI： 10.1109/EMBC.2015.7318299 　

    ISSN： 1557-170X

  7. Brain-machine interface to control a prosthetic arm with monkey ECoGs during periodic movements Peer-reviewed

    Soichiro Morishita, Keita Sato, Hidenori Watanabe, Yukio Nishimura, Tadashi Isa, Ryu Kato, Tatsuhiro Nakamura, Hiroshi Yokoi

    FRONTIERS IN NEUROSCIENCE　8　(417)　1-9　2014/12

    DOI： 10.3389/fnins.2014.00417 　

    ISSN： 1662-453X

  8. FREQUENCY-DEPENDENT SIGNAL PROCESSING IN APICAL DENDRITES OF HIPPOCAMPAL CA1 PYRAMIDAL CELLS Peer-reviewed

    H. Watanabe, H. Tsubokawa, M. Tsukada, T. Aihara

    NEUROSCIENCE　278　194-210　2014/10

    DOI： 10.1016/j.neuroscience.2014.07.069 　

    ISSN： 0306-4522

    eISSN： 1873-7544

  9. Reconstruction of intracortical whisker-evoked local field potential from electrocorticogram using a model trained for spontaneous activity in the rat barrel cortex Peer-reviewed

    Hidenori Watanabe, Tomoya Sakatani, Takafumi Suzuki, Masa-aki Sato, Yukio Nishimura, Atsushi Nambu, Mitsuo Kawato, Tadashi Isa

    NEUROSCIENCE RESEARCH　87　40-48　2014/10

    DOI： 10.1016/j.neures.2014.06.010 　

    ISSN： 0168-0102

    eISSN： 1872-8111

  10. Decoding grasp force profile from electrocorticography signals in non-human primate sensorimotor cortex Peer-reviewed

    Chao Chen, Duk Shin, Hidenori Watanabe, Yasuhiko Nakanishi, Hiroyuki Kambara, Natsue Yoshimura, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    NEUROSCIENCE RESEARCH　83　1-7　2014/06

    DOI： 10.1016/j.neures.2014.03.010 　

    ISSN： 0168-0102

    eISSN： 1872-8111

  11. Decoding of the spike timing of primary afferents during voluntary arm movements in monkeys Peer-reviewed

    Tatsuya Umeda, Hidenori Watanabe, Masa-aki Sato, Mitsuo Kawato, Tadashi Isa, Yukio Nishimura

    FRONTIERS IN NEUROSCIENCE　8　2014/05

    DOI： 10.3389/fnins.2014.00097 　

    ISSN： 1662-453X

  12. Decoding of the spike timing of primary afferents during voluntary arm movements in monkeys Peer-reviewed

    Tatsuya Umeda, Hidenori Watanabe, Masa-Aki Sato, Mitsuo Kawato, Tadashi Isa, Yukio Nishimura

    Frontiers in Neuroscience　8　(8)　97　2014

    DOI： 10.3389/fnins.2014.00097 　

    ISSN： 1662-453X 1662-4548

  13. Brain-machine interface to control a prosthetic arm with monkey ECoGs during periodic movements Peer-reviewed

    Soichiro Morishita, Keita Sato, Hidenori Watanabe, Yukio Nishimura, Tadashi Isa, Ryu Kato, Tatsuhiro Nakamura, Hiroshi Yokoi

    Frontiers in Neuroscience　8　417　2014

    DOI： 10.3389/fnins.2014.00417 　

    ISSN： 1662-453X 1662-4548

  14. Phase and magnitude spatiotemporal dynamics of beta oscillation in electrocorticography (ECoG) in the monkey motor cortex at the onset of 3D reaching movements Peer-reviewed

    Hidenori Watanabe, Kazutaka Takahashi, Yukio Nishimura, Tadashi Isa

    2014 36TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)　2014　5196-5199　2014

    DOI： 10.1109/EMBC.2014.6944796 　

    ISSN： 1557-170X

  15. Prediction of Hand Trajectory from Electrocorticography Signals in Primary Motor Cortex Peer-reviewed

    Chao Chen, Duk Shin, Hidenori Watanabe, Yasuhiko Nakanishi, Hiroyuki Kambara, Natsue Yoshimura, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    PLOS ONE　8　(12)　e83534　2013/12

    DOI： 10.1371/journal.pone.0083534 　

    ISSN： 1932-6203

  16. Discrimination Analysis and Movement Decision of the Prosthetic Arm by Using Monkey ECoGs Data Associated with Self-feeding Motions Peer-reviewed

    SATO Keita, MORISHITA Soichiro, WATANABE Hidenori, NISHIMURA Yukio, KATO Ryu, ISA Tadashi, YOKOI Hiroshi

    31　(1)　51-59　2013

    ISSN： 0289-1824

  17. Prediction of Muscle Activities from Electrocorticograms in Primary Motor Cortex of Primates Peer-reviewed

    Duk Shin, Hidenori Watanabe, Hiroyuki Kambara, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    PLOS ONE　7　(10)　e47992　2012/10

    DOI： 10.1371/journal.pone.0047992 　

    ISSN： 1932-6203

  18. Discrimination Analysis and Movement Decision of the prosthesis of the Monkey ECoGs Data Associated with Self-feeding Motions Peer-reviewed

    Keita Sato, Soichiro Morishita, Yukio Nishimura, Hidenori Watanabe, Ryu Kato, Atsushi Nambu, Tadashi Isa, Hiroshi Yokoi

    Triangle Symposium on Advanced ICT 2012 (TriSAI 2012)　SJ19　2012/09

  19. Reconstruction of movement-related intracortical activity from micro-electrocorticogram array signals in monkey primary motor cortex Peer-reviewed

    Hidenori Watanabe, Masa-aki Sato, Takafumi Suzuki, Atsushi Nambu, Yukio Nishimura, Mitsuo Kawato, Tadashi Isa

    JOURNAL OF NEURAL ENGINEERING　9　(3)　036006　2012/06

    DOI： 10.1088/1741-2560/9/3/036006 　

    ISSN： 1741-2560

  20. fMRI analysis of prosthetic hand rehabilitation using a brain-machine interface

    Hiroshi Yokoi, Keita Sato, Souichiro Morishita, Tatuhiro Nakamura, Ryu Kato, Tatsuya Umeda, Hidenori Watanabe, Yukio Nishimura, Tadashi Isa, Katsunori Ikoma, Tamaki Miyamoto, Osamu Yamamura

    Advances in Therapeutic Engineering　219-250　2012/01/01

    Publisher: CRC Press

    DOI： 10.1201/b13729 　

  21. サル一次運動野における皮質内局所電位とECoG信号による前腕到達把持運動軌道の推定(Regression of forearm reach and grasp movement trajectories using intracortical local field potentials and electrocorticogram signals in monkey primary motor cortex)

    渡辺 秀典, 山下 宙人, 澤畑 博人, 坂谷 智也, 戸川 森雄, 吉田 正俊, 戸田 春男, 佐藤 雅昭, 長谷川 功, 鈴木 隆文, 川人 光男, 伊佐 正

    神経化学　49　(2-3)　497-497　2010/08

    Publisher: 日本神経化学会

    ISSN： 0037-3796

  22. Classification analysis of Monkey ECoG data for reaching motion

    Keita Sato, Tatsuhiro Nakamura, Soichiro Morishita, Tatsuya Umeda, Hidenori Watanabe, Ryu Kato, Tadashi Isa, Hiroshi Yokoi

    UEC & SJTU Proceedings of 3rd International Symposium on Robot and Artificial Intelligence　確認中　2010/06

  23. The relation between spike-timing dependent plasticity and Ca2+ dynamics in the hippocampal CA1 network Peer-reviewed

    T. Aihara, Y. Abiru, Y. Yamazaki, H. Watanabe, Y. Fukushima, M. Tsukada

    Neuroscience　145　(1)　80-87　2007/03/02

    DOI： 10.1016/j.neuroscience.2006.11.025 　

    ISSN： 0306-4522

  24. Phase shift of subthreshold theta oscillation in hippocampal CA1 pyramidal cell membrane by excitatory synaptic inputs. Peer-reviewed

    Watanabe H, Aihara T, Tsukada M

    Neuroscience　140　(4)　1189-1199　2006/07

    DOI： 10.1016/j.neuroscience.2006.02.085 　

    ISSN： 0306-4522

  25. Change of memory formation according to STDP in a continuous-time neural network model Peer-reviewed

    Hidenori Watanabe, Masataka Watanabe, Kazuyuki Aihara, Shunsuke Kondo

    Systems and Computers in Japan　35　(12)　57-66　2004/11/15

    DOI： 10.1002/scj.10324 　

    ISSN： 0882-1666

  26. 連続時間型連想記憶モデルにおけるSTDPによる記憶の貯蓄構造変化 Peer-reviewed

    渡辺秀典, 渡辺正峰, 合原一幸, 近藤駿介

    電子情報通信学会論文誌　85-DII　(3)　504-513　2002

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Misc. 22

  1. Prediction of Muscle Activities from Electrocorticograms in Primary Motor Cortex of Primates (vol 7, e47992, 2012)

    D. Shin, H. Watanabe, H. Kambara, A. Nambu, T. Isa

    PLOS ONE　9　(3)　2014/03

    DOI： 10.1371/journal.pone.0092653 　

    ISSN： 1932-6203

  2. サル硬膜下電位からのリーチングタスクの状態判別率向上を目指した次元圧縮法

    坂井郁也, 森下壮一郎, 西村幸男, 渡辺秀典, 加藤龍, 梅田達也, 伊佐正, 横井浩史

    自律分散システム・シンポジウム(CD-ROM)　26th　2014

  3. 上腕電動義手のブレイン-マシン・インタフェース制御のための周期的運動中のサル硬膜下電位からの筋電位推定

    森下壮一郎, 佐藤圭太, 渡辺秀典, 西村幸男, 加藤龍, 中村達弘, 伊佐正, 横井浩史, 横井浩史

    計測自動制御学会システム・情報部門学術講演会講演論文集(CD-ROM)　2014　2014

  4. Control of an arm robot using decoded muscle activities from electrocorticograms

    Duk shin, Hidenori Watanabe, Yasuhiko Nakanishi, Hiroyuki Kambara, Atsushi Nambu, Yukio Nishimura, Yasuharu Koike

    ISEK2014　2014

  5. Phase and magnitude spatiotemporal dynamics of beta oscillation in electrocorticography (ECoG) in the monkey motor cortex at the onset of 3D reaching movements Peer-reviewed

    Hidenori Watanabe, Kazutaka Takahashi, Yukio Nishimura, Tadashi Isa

    2014 36TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)　5196-5199　2014

    ISSN： 1557-170X

  6. Prediction of joint angle from muscle activities decoded from electrocorticograms

    Duk Shin, Chao Chen, Yasuhiko Nakanishi, Hiroyuki Kambara, Natsue Yoshimura, Hidenori Watanabe, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    ISHF2013　2013

  7. Decoding of arm movement from electrocorticogram in primary motor cortex

    Chao Chen, Duk Shin, Yasuhiko Nakanishi, Hiroyuki Kambara, Natsue Yoshimura, Hidenori Watanabe, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    Neuro 2013　2013

  8. Decoding Muscle Activities from Electrocorticogram in Primary Motor Cortex

    Duk Shin, Hidenori Watanabe, Hiroyuki Kambara, Natsue Yoshimura, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    SNR 2013　2013

  9. Prediction of Hand Trajectory from?Electrocorticogram in Primates

    Chao Chen, Duk Shin, Yasuhiko Nakanishi, Hidenori Watanabe, Hiroyuki Kambara, Natsue Yoshimura, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    SNR 2013　2013

  10. 一次運動野の皮質脳波を用いた腕軌道のデコーディング

    陳超、 辛徳, 中西康彦, 神原裕行, 吉村奈津江, 渡辺秀典, 南部篤, 伊佐正, 西村幸男, 小池康晴

    第36回日本神経科学大会　2013

  11. サルの皮質脳波から推定した筋電信号を用いた腕の角度の推定

    辛徳, 中西康彦, 陳超, 神原裕行, 吉村奈津江, 渡辺秀典, 南部篤, 伊佐正, 西村幸男, 小池康晴

    第36回日本神経科学大会　2013

  12. Prediction of Joint angle from Muscle Activities decoded from Electrocorticograms in Primary Motor Cortex

    SHIN Duk, NAKANISHI Yasuhiko, KAMBARA Hiroyuki, YOSHIMURA Natsue, WATANABE Hidenori, NAMBU Atsushi, ISA Tadashi, NISHIMURA Yukio, KOIKE Yasuharu

    IEICE technical report. Neurocomputing　112　(298)　5-8　2012/11/09

    Publisher: The Institute of Electronics, Information and Communication Engineers

    ISSN： 0913-5685

    More details Close

    Electrocorticography (ECoG) has drawn attention as an effective recording approach for less invasive brain-machine interfaces (BMI). Previous studies succeeded in classifying the movement direction and predicting hand trajectories from ECoGs. Despite such successful studies, there still remain considerable works for the purpose of realizing an ECoG-based BMI robot. We developed a method to predict multiple muscle activities from ECoG measurements. We also verified that ECoG signals could be effective for predicting muscle activities in time varying series for preforming sequential movements. Each ECoG signal was filtered by different bandpass filters for sensorimotor rhythms, normalized by the standard z-score, and smoothed by a Gaussian filter. We used sparse linear regression to find the best fit between frequency bands of ECoG and electromyogram (EMG). We also predicted angle of 4 DOF robot arm from the decoded EMG using 3-layer neural network. Consequently, this study shows that it could derive online prediction of angle of robot arm from ECoG signals.

  13. Prediction of Joint angle from Muscle Activities decoded from Electrocorticograms in Primary Motor Cortex

    SHIN Duk, NAKANISHI Yasuhiko, KAMBARA Hiroyuki, YOSHIMURA Natsue, WATANABE Hidenori, NAMBU Atsushi, ISA Tadashi, NISHIMURA Yukio, KOIKE Yasuharu

    IEICE technical report. ME and bio cybernetics　112　(297)　61-64　2012/11/09

    Publisher: 一般社団法人電子情報通信学会

    ISSN： 0913-5685

    More details Close

    Electrocorticography (ECoG) has drawn attention as an effective recording approach for less invasive brain-machine interfaces (BMI). Previous studies succeeded in classifying the movement direction and predicting hand trajectories from ECoGs. Despite such successful studies, there still remain considerable works for the purpose of realizing an ECoG-based BMI robot. We developed a method to predict multiple muscle activities from ECoG measurements. We also verified that ECoG signals could be effective for predicting muscle activities in time varying series for preforming sequential movements. Each ECoG signal was filtered by different bandpass filters for sensorimotor rhythms, normalized by the standard z-score, and smoothed by a Gaussian filter. We used sparse linear regression to find the best fit between frequency bands of ECoG and electromyogram (EMG). We also predicted angle of 4 DOF robot arm from the decoded EMG using 3-layer neural network. Consequently, this study shows that it could derive online prediction of angle of robot arm from ECoG signals.

  14. Reconstruction of muscle activities from electrocorticograms in primary motor cortex

    Duk Shin, Hidenori Watanabe, Hiroyuki Kambara, Natsue Yoshimura, Atsushi Nambu, Tadashi Isa, Yukio Nishimura, Yasuharu Koike

    Neuro2012　2012

  15. P2-u06 A study of a method for motion determination of electrical upper arm using state discrimination of activity patterns in cranial nerves of a monkey Peer-reviewed

    Soichiro Morishita, Sato Keita, Daijiro Mochizuki, Tatsuhiro Nakamura, Yukio Nishimura, Hidenori Watanabe, Ryu Kato, Tadashi Isa, Hiroshi Yokoi

    NEUROSCIENCE RESEARCH　71　E204-E204　2011

    DOI： 10.1016/j.neures.2011.07.883 　

    ISSN： 0168-0102

  16. Estimation of the intracortical LFPs from microECoGs based on spontaneous neuronal activities Peer-reviewed

    Tomoya Sakatani, Hidenori Watanabe, Yukio Nishimura, Atsushi Nambu, Isao Hasegawa, Takafumi Suzuki, Masa-aki Sato, Mitsuo Kawato, Tadashi Isa

    NEUROSCIENCE RESEARCH　71　E203-E203　2011

    DOI： 10.1016/j.neures.2011.07.877 　

    ISSN： 0168-0102

  17. Reconstruction of movement-related intracortical potentials from micro-electrocorticogram signals in monkey primary motor cortex Peer-reviewed

    Hidenori Watanabe, Masa-aki Sato, Takafumi Suzuki, Mitsuo Kawato, Yukio Nishimura, Atsushi Nambu, Tadashi Isa

    NEUROSCIENCE RESEARCH　71　E201-E201　2011

    DOI： 10.1016/j.neures.2011.07.869 　

    ISSN： 0168-0102

  18. Estimation of the intracortical neuronal dynamics from the multi-channel ECoG signals Peer-reviewed

    Tomoya Sakatani, Hidenori Watanabe, Morio Togawa, Masatoshi Yoshida, Isao Hasegawa, Takafumi Suzuki, Masa-aki Sato, Mitsuo Kawato, Tadashi Isa

    NEUROSCIENCE RESEARCH　68　E326-E326　2010

    DOI： 10.1016/j.neures.2010.07.1446 　

    ISSN： 0168-0102

  19. Regression of forearm reach and grasp movement trajectories using intracortical local field potentials and electrocorticogram signals in monkey primary motor cortex Peer-reviewed

    Hidenori Watanabe, Okito Yamashita, Hirohito Sawahata, Tomoya Sakatani, Morio Togawa, Masatoshi Yashida, Haruo Toda, Masa-aki Sato, Isao Hasegawa, Takafumi Suzuki, Mitsuo Kawato, Tadashi Isa

    NEUROSCIENCE RESEARCH　68　E83-E83　2010

    DOI： 10.1016/j.neures.2010.07.132 　

    ISSN： 0168-0102

  20. Multi-channel recording of the electrocorticogram in anesthetized rats with parylene electrode arrays Peer-reviewed

    Hidenori Watanabe, Tomoya Sakatani, Morio Togawa, Masatoshi Yoshida, Tadashi Isa, Isao Hasegawa, Takafumi Suzuki

    NEUROSCIENCE RESEARCH　65　S181-S181　2009

    DOI： 10.1016/j.neures.2009.09.967 　

    ISSN： 0168-0102

  21. Frequency-dependent response property of the dendrites in the hippocampal CA1 pyramidal cells Peer-reviewed

    Hidenori Watanabe, Hiroshi Tsubokawa, Takeshi Aihara, Minoru Tsukada

    NEUROSCIENCE RESEARCH　58　S186-S186　2007

    DOI： 10.1016/j.neures.2007.06.816 　

    ISSN： 0168-0102

  22. The relation between Ca^<2+> influx and the magnitude of STDP in the hippocampal neural network

    KASHIWAGI Yasutoshi, AVIL Yoichi, WATANABE Hidenori, AIHARA Takeshi, TSUKADA Minoru

    IEICE technical report. Neurocomputing　103　(732)　1-4　2004/03/10

    Publisher: The Institute of Electronics, Information and Communication Engineers

    ISSN： 0913-5685

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    In the hippocampal CA1 area, repetitive correlated spiking of pre- and postsynaptic neurons can induce LTP and LTD , depending on the timing of the pre- and postsynaptic excitation(Spike timing Dependent Plasticity). While, it is shown that LTP and LTD are triggered depending on the level of postsynaptic intracellular calcium concentration. In this study , Ca^<2+> influx induced by the protocol of timing between pre- and postsynaptic excitation were spatially investigated by using the calcium imaging method in the hippocampal CA1 area. We analized the dynamics of calcium influx during repetitive stimulus and discussed the relatio between the dynamics and themaghifaile of STDP that the magnitude of LTP and LTD closely related to the velocity of calcium influx during repetitive stimulus.

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Books and Other Publications 1

  1. Advances in Therapeutic Engineering

    Wenwei Yu, Subhagata Chattopadhyay, Teik-Cheng Lim, U. Rajendra Acharya

    CRC Press　2012/12

Presentations 5

  1. Horizontal information flow in the primary motor cortex at the β-frequency ranges in neural responses to visual instruction cue in a visuomotor task

    Hidenori WATANABE, Kazutaka TAKAHASHI, Nicholas G. HATSOPOULOS, Hajime MUSHIAKE

    Society for Neuroscience　2024/10/06

  2. Spatiotemporal dynamics of beta oscillation phase in the monkey motor cortex International-presentation Invited

    Hidenori Watanabe

    Neural Oscillation Conference,Shirankaikan, Kyoto University, Kyoto, Japan.　2019/11/19

  3. 3D recordings using the Matrix Array International-presentation Invited

    Hidenori Watanabe

    Society for Neuroscience Annual Meeting, NeuroNexus booth Hall A, McCormick Place. Chicago, IL, US.　2019/10/20

  4. Phase locking of β oscillation in electrocorticography (ECoG) in the monkey motor cortex at the onset of EMGs and 3D reaching movements.

    Hidenori Watanabe

    The 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society　2015/08/26

  5. Phase and magnitude spatiotemporal dynamics of β oscillation in electrocorticography (ECoG) in the monkey motor cortex at the onset of 3D reaching movements.

    Hidenori Watanabe

    The 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society　2014/08/29

Research Projects 11

  1. 多様なこころを脳と身体性機能に基づいてつなぐ「自在ホンヤク機」の開発

    筒井 健一郎

    Offer Organization: 科学技術振興機構

    System: 戦略的な研究開発の推進 ムーンショット型研究開発事業

    Institution: 東北大学

    2022 - 2026

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    さまざまな場面でコミュニケーションを支援する「自在ホンヤク機」を開発し、多様な人々を包摂する社会をもたらします。神経科学・分子生命科学と、VR/AR・ロボット工学の分野の研究者が協力して、こころの状態を定量化する技術を研究するとともに、知覚・認知や運動機能への介入法を研究します。これらの成果を融合して開発する「自在ホンヤク機」は、個人、個人間、あるいは、数人から数十人程度の小グループを対象としてコミュニケーション支援を行います。

  2. Do the beta oscillations in the cerebral motor cortex represent perceptual information?

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2022/04 - 2025/03

  3. サル覚醒行動下の光刺激による手指運動変化とベータ波位相の関係解明 Competitive

    渡辺秀典

    Offer Organization: 文科省

    System: 国際共同研究加速基金（国際共同研究強化）

    2018/05 - 2022/03

  4. マルチスケール・マルチモーダルマップ法 によるマーモセット脳の構造・機能解析 Competitive

    南部篤, 虫明元

    Offer Organization: 国立研究開発法人日本医療研究開発機構(AMED)

    System: 革新的技術による脳機能ネットワークの全容解明プロジェクト

    2016/04 - 2020/03

  5. C01 計画班「動物モ デルへの双方向性計測操作による発振現象の理解」 Competitive

    虫明元

    Offer Organization: 文科省

    System: 新学術領域研究「非線形発振現象を基盤としたヒューマンネイチャーの理解」

    2015/07 - 2020/03

  6. 大脳皮質運動野におけるベータ脳波の機能的意味を解明する Competitive

    渡辺秀典

    Offer Organization: 文科省

    System: 科学研究費補助金 基盤研究(C)

    2015/04 - 2018/03

  7. ブレイン・マシン・インターフェース（ＢＭＩ）の開発 Competitive

    南部篤, 西村幸男

    Offer Organization: 文科省

    System: 脳科学研究戦略推進プログラム

    2008/07 - 2012/03

  8. 単一神経細胞におけるマルチユニット演算素子の検証 Competitive

    渡辺秀典

    Offer Organization: 文科省

    System: 科学研究費補助金 若手研究(B)

    2008/04 - 2009/03

  9. 可塑性神経回路網の情報統合とそのダイナミクス Competitive

    相原威

    Offer Organization: 文科省

    System: 科学研究費補助金 特定領域研究「統合脳」

    2006/04 - 2007/03

  10. 記憶・学習の時空間情報処理とそのダイナミクス Competitive

    相原威

    Offer Organization: 文科省

    System: 科学研究費補助金 特定領域研究「統合脳」

    2005/04 - 2006/03

  11. 海馬における複数シータ活動仮説の提案と生理実験による検証 Competitive

    渡辺秀典

    Offer Organization: 日本学術振興会

    System: 特別研究員

    2003/04 - 2004/03

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Teaching Experience 8

  1. 学位論文審査委員　東北大学医学系研究科

  2. IBRO-APRC Advanced School of Neuroscience in OKAZAKI, JAPAN　生理学研究所

  3. 生理科学実験技術トレーニングコース(認知行動発達研究機構部門: 行動下動物での実験・データ解析の基礎)　生理学研究所

  4. 生理科学実験技術トレーニングコース(認知行動発達研究機構部門: 麻酔動物での電気生理実験)　生理学研究所

  5. 卒業研究　東北大学保健学科検査技術科学専攻

  6. 基礎ゼミ（脳科学）　東北大学全学教育

  7. 基礎医学修練　東北大学医学部

  8. 生体機能学実習脳波筋電　東北大学医学部

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Media Coverage 14

  1. Delta gamma oscillatory interactions support visuomotor processing in the lateral frontal cortex of macaque monkeys

    Clear Sky Science　https://www.clearskyscience.com/en/10.1038/s41598-026-36628-6/

    2026/05/11

    Type: Internet

  2. 脳はどうやって「見てから動く」の？ サルの脳研究から見えてきた、脳内リズムの協力プレー

    東北大学 プレスリリース・研究成果　https://www.tohoku.ac.jp/japanese/2026/02/press20260213-02-brain.html

    2026/02/13

    Type: Other

  3. 脳神経の役割 解明に弾み 狙った細胞だけ操る…光遺伝学 視力回復への応用研究

    読売新聞

    2023/07/09

    Type: Newspaper, magazine

  4. Optogenetic Stimulation Of The Motor Cortex Successfully Induced Arm Movements In Monkeys

    Scienmag

    2020/07/06

    Type: Internet

  5. Researchers use optogenetics to successfully induce arm movements in monkeys

    News-Medical.Net

    2020/07/06

    Type: Internet

  6. Optogenetic Stimulation of the Motor Cortex Successfully Induced Arm Movements in Monkeys

    Neuroscience News

    2020/07/06

    Type: Internet

  7. Optogenetic stimulation of the motor cortex successfully induced arm movements in monkeys

    the American Association for the Advancement of Science (AAAS)　the American Association for the Advancement of Science (AAAS)

    2020/07/03

    Type: Internet

  8. サルの脳に光を当て、手を操作 治療法開発へ期待、生理研

    共同通信　Yahoo!ニュース

    2020/06/26

  9. Forelimb movements evoked by optogenetic stimulation of the macaque motor cortex

    News Break

    2020/06/26

    Type: Internet

  10. サルの脳に光を当て、手を操作 治療法開発へ期待、生理研

    東京新聞　東京新聞

    2020/06/26

  11. 生理学研究所・東北大など、神経細胞を光で操作しサルの手を動かすことに成功

    日本経済新聞　日本経済新聞

    2020/06/26

  12. サルの脳に光を当て、手を操作

    共同通信　共同通信

    2020/06/26

    Type: Newspaper, magazine

  13. 脳内部の神経活動をやさしく正確に推定 脳表面に電極シートを貼るだけ

    科学新聞

    2012/06/08

    Type: Newspaper, magazine

  14. 脳表面の電気記録（ＥＣｏＧ）から脳内部の神経活動の推定に成功

    共同通信社

    2012/05

    Type: Internet

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