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Doctor of Philosophy (The University of Tokyo)
Details of the Researcher
Research Interests 9
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Techonology Governance
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Strong Autonomy
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Agentic AI
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Autonomous Artificial Intteligence
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Ethics
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Reinforcement Learning
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Artificial intelligence
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Machine learning
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Sequence analysis
Research Areas 2
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Informatics / Intelligent informatics /
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Informatics / Biological, health, and medical informatics /
Papers 49
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Transforming Social Meanings of Rice Produced in Miyagi Prefecture after the Great East Japan Earthquake: An 11-Year Twitter Analysis of Reputational Damage, Reconstruction Support, and Regional Branding International-journal Peer-reviewed
Okano Y, Yamada KD
Asia-Pacific Journal: Japan Focus 2026
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ConWorldGAN: Generation of Complex Semantic Structures in 3D Voxel Worlds from a Single Example International-journal Peer-reviewed
Zaiyr S, Yamada KD, Zielewski MR
Artificial Intelligence and Interactive Digital Entertainment 2026
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TimePre: Bridging Accuracy, Efficiency, and Stability in Probabilistic Time-Series Forecasting International-journal International-coauthorship Peer-reviewed
Jiang L, Xu L, Li P, Hou D, Ge Q, Zhuang D, Xing S, Chen W, Gao X, Chen T, Zhan X, Zhang X, Zhang Z, Tu Z, Zielewski MR, Yamada KD, Lin F
Transactions on Machine Learning Research 2026
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A Compact Kolmogorov-Arnold Network Mixer for Long-term Time Series Forecasting International-journal International-coauthorship Peer-reviewed
Jiang L., Hou D., Wang Y., Su Y., Xing S., Chen W., Zhang X., Tu Z., Zhang Z., Lin F., Zielewski MR, Yamada KD
Scientific Reports 2026
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The Emergence of Concept Cafe Culture in Japan: An Ontology-inspired Analysis based on Original Concept Cafe Data and Anime Role Images International-journal Peer-reviewed
Okano Y, Yamada KD
East Asian Journal of Popular Culture 2026
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Text-Guided Object Removal for Drone-Based 3D Reconstruction with Gaussian Splatting International-journal Peer-reviewed
Kikuchi Y, Yamada KD, Koike A
IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops 2026
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NexusFlow: Unifying Disparate Tasks under Partial Supervision via Invertible Flow Networks International-journal International-coauthorship Peer-reviewed
Lin F, Wang Y, Guo Y, Huang Z, Huang X, Zhang H, Yamada KD, Tu Z, Ren L, Zhang Z
IEEE/CVF Conference on Computer Vision and Pattern Recognition 2026
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Physics-Aware Video Instance Removal Benchmark International-journal International-coauthorship Peer-reviewed
Li Z, Chen X, Jiang L, Hou D, Yamada KD, Lin F, Gao X, Tu Z
IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops 2026
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Procedural Content Generation via Generative Artificial Intelligence International-journal International-coauthorship Peer-reviewed
Mao X., Yu W., Okawara Y., Zhan X., Yamada KD, Zielewski MR
Interdisciplinary Information Sciences 2026
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Simulating Metabolic Pathways to Enhance Interpretations of Metabolome Genome-wide Association Studies International-journal Peer-reviewed
Kodate S, Sato M, Hishinuma E, Kojima K, Motoike IN, ToMMo Study Group, Koshiba S, Yamamoto M, Yamada KD, Kinoshita K
Scientific Reports 2025
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Effect of Cumulative Exposure on the Efficacy of Paroxetine: a Population Pharmacokinetic-pharmacodynamic and Machine Learning Analyses International-journal Peer-reviewed
Shigetome K, Egarashi T, Tomita T, Higa N, Iwashita K, Morita K, Nishimura M, Kankeko T, Maeda H, Yamada KD, Kajiwara-Morita A, Oniki K, Yasui-Furukori N, Saruwatari J
Pharmacometrics and Systems Pharmacology 2025
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GPS: A Probabilistic Distributional Similarity with Gumbel Priors for Set-to-Set Matching International-journal International-coauthorship Peer-reviewed
Lin F, Liu H, Zhang Z, Morales J, Zhang HK, Yamada KD, Kolachalama V, Saligrama V
International Conference on Learning Representations 2025
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Learning Random Numbers to Realize Appendable Memory System for Artificial Intelligence to Acquire New Knowledge after Deployment International-journal International-coauthorship Peer-reviewed
Kubota A, Kodate S, Li Y, Lin F, Fukuda H, Baladram MS, Yamada KD
Interdisciplinary Information Sciences 2025
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Loss Distillation via Gradient Matching for Point Cloud Completion with Weighted Chamfer Distance International-journal International-coauthorship Peer-reviewed
Lin F, Liu H, Zhou H, Hou S, Yamada KD, Fischer GS, Li Y, Zhang H, Zhang Z
IEEE/RSJ International Conference on Intelligent Robots and Systems 2024
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Question generation for English reading comprehension exercises using Transformers International-journal Peer-reviewed
Maas A, Yamada KD, Nagahama T, Kawada T, Horita T
Letters on Informatics and Interdisciplinary Research 2024
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InfoCD: A contrastive chamfer distance loss for point cloud completion International-journal International-coauthorship Peer-reviewed
Lin F, Yue Y, Zhang Z, Hou S, Yamada KD, Kolachalama VB, Saligrama V
Advances in Neural Information Processing Systems 2023
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Hyperbolic chamfer distance for point cloud completion International-journal International-coauthorship Peer-reviewed
Lin F, Yue Y, Hou S, Yu X, Xu Y, Yamada KD, Zhang Z
International Conference on Computer Vision 2023
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Serum fatty acid composition balance by fuzzy c-means method in individuals with or without metabolic dysfunction-associated fatty liver disease International-journal Peer-reviewed
Nagase Y, Satoh T, Shigetome K, Tokumaru N, Matsumoto E, Yamada KD, Imafuku T, Watanabe H, Maruyama T, Ogata Y, Yoshida M, Saruwatari J, Oniki K
Nutrients 15 (4) 809-809 2023
DOI: 10.3390/nu15040809
eISSN: 2072-6643
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Identifying latent traits of questions for controllable machine generation International-journal Peer-reviewed
Maas A, Kawada T, Yamada K, Nagahama T, Horita T
EdMedia + Innovate Learning 2022
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Redox imaging of dextran sodium sulfate-induced colitis mice treated with nitric oxide synthase inhibitors International-journal Peer-reviewed
Yasukawa K, Yamada K, Tokuda H, Koyama S, Utsumi H
Advances in Redox Research 6 100047-100047 2022
DOI: 10.1016/j.arres.2022.100047
ISSN: 2667-1379
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Relation is an option for processing context information International-journal Peer-reviewed
Yamada KD, Baladram MS, Lin F
Frontiers in Artificial Intelligence 5 2022
eISSN: 2624-8212
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Cosmos Propagation Network: Deep learning model for point cloud completion International-journal Peer-reviewed
Lin F, Xu Y, Zhang Z, Gao C, Yamada KD
Neurocomputing 507 221-234 2022
DOI: 10.1016/j.neucom.2022.08.007
ISSN: 0925-2312
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Progress in research on implementing machine consciousness International-journal Peer-reviewed
Yamada KD, Baladram MS, Lin F
Interdisciplinary Information Sciences 28 (1) 95-105 2022
ISSN: 1340-9050
eISSN: 1347-6157
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An effective convolutional neural network for visualized understanding transboundary air pollution based on Himawari-8 satellite images International-journal Peer-reviewed
Lin F, Gao C, Yamada KD
IEEE Geoscience and Remote Sensing Letters 19 1-5 2022
DOI: 10.1109/LGRS.2021.3102939
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Developing a novel recurrent neural network architecture with fewer parameters and good learning performance International-journal Peer-reviewed
Yamada KD, Lin F, Nakamura T
Interdisciplinary Information Sciences 27 (1) 25-40 2021
ISSN: 1340-9050
eISSN: 1347-6157
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Introduction to supervised machine learning for data science International-journal Peer-reviewed
Baladram MS, Koike A, Yamada KD
Interdisciplinary Information Sciences 26 (1) 87-121 2020
ISSN: 1340-9050
eISSN: 1347-6157
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In vivo redox imaging of dextran sodium sulfate-induced colitis in mice using Overhauser-enhanced magnetic resonance imaging International-journal Peer-reviewed
Yasukawa K, Hirago A, Yamada K, Tun X, Ohkuma K, Utsumi H
Free Radical Biology and Medicine 136 1-11 2019
DOI: 10.1016/j.freeradbiomed.2019.03.025
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MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization International-journal Peer-reviewed
Katoh K, Rozewicki J, Yamada KD
Briefings in Bioinformatics 20 (4) 1160-1166 2019
DOI: 10.1093/bib/bbx108
ISSN: 1467-5463
eISSN: 1477-4054
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De novo profile generation based on sequence context specificity with the long short-term memory network International-journal Peer-reviewed
Yamada KD, Kinoshita K
BMC Bioinformatics 2018
DOI: 10.1186/s12859-018-2284-1
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Parallelization of MAFFT for large-scale multiple sequence alignments International-journal Peer-reviewed
Nakamura T, Yamada KD, Tomii K, Katoh K
Bioinformatics 34 (14) 2490-2492 2018
DOI: 10.1093/bioinformatics/bty121
ISSN: 1367-4803
eISSN: 1460-2059
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Derivative-free neural network for optimizing the scoring functions associated with dynamic programming of pairwise-profile alignment International-journal Peer-reviewed
Yamada KD
Algorithms for molecular biology 2018
DOI: 10.1186/s13015-018-0123-6
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Designing better diffracting crystals of biotin carboxyl carrier protein from Pyrococcus horikoshii by a mutation based on crystal-packing propensity of amino acids International-journal Peer-reviewed
Yamada KD, Kunishima N, Matsuura Y, Nakai K, Naitow H, Fukasawa Y, Tomii K
Acta Crystallographica Section D 73 (Pt 9) 757-766 2017
DOI: 10.1107/S2059798317010932
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Identification of the sequence determinants of protein N-terminal acetylation through a decision tree approach International-journal International-coauthorship Peer-reviewed
Yamada KD, Omori S, Nish H, Miyagi M
BMC Bioinformatics 18 (1) 289-289 2017
DOI: 10.1186/s12859-017-1699-4
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Protein sequence-similarity search acceleration using a heuristic algorithm with a sensitive matrix International-journal Peer-reviewed
Lim K, Yamada KD, Frith MC, Tomii K
Journal of Structural and Functional Genomics 17 (4) 147-154 2016
DOI: 10.1007/s10969-016-9210-4
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Application of the MAFFT sequence alignment program to large data - reexamination of the usefulness of chained guide trees International-journal Peer-reviewed
Yamada KD, Tomii K, Katoh K
Bioinformatics 32 (21) 3246-3251 2016
DOI: 10.1093/bioinformatics/btw412
ISSN: 1367-4803
eISSN: 1460-2059
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Structural characterization of single nucleotide variants at ligand binding sites and enzyme active sites of human proteins International-journal Peer-reviewed
Yamada KD, Nishi H, Nakata J, Kinoshita K
Biophysics and Physicobiology 13 157-163 2016
DOI: 10.2142/biophysico.13.0_157
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Identification of hepta-histidine as a candidate drug for Huntington’s disease by in silico-in vitro-in vivo-integrated screens of chemical libraries International-journal International-coauthorship Peer-reviewed
Imamura T, Fujita K, Tagawa K, Ikura T, Chen X, Homma H, Tamura T, Mao Y, Taniguchi JB, Motoki K, Nakabayashi M, Ito N, Yamada K, Tomii K, Okano H, Kaye J, Finkbeiner S, Okazawa H
Scientific Reports 6 33861-33861 2016
DOI: 10.1038/srep33861
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Intrinsically disordered region of influenza A NP regulates viral genome packaging via interactions with viral RNA and host PI(4,5)P2 International-journal Peer-reviewed
Kakisaka M, Yamada K, Yamaji-Hasegawa A, Kobayashi T, Aida Y
Virology 496 116-126 2016
DOI: 10.1016/j.virol.2016.05.018
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Prediction of homo- and hetero-protein complexes by protein docking and template-based modeling: a CASP-CAPRI experiment International-journal International-coauthorship Peer-reviewed
Lensink MF, Velankar S, Kryshtafovych A, Huang SY, Schneidman-Duhovny D, Sali A, Segura J, Fernandez-Fuentes N, Viswanath S, Elber R, Grudinin S, Popov P, Neveu E, Lee H, Baek M, Park S, Heo L, Rie Lee G, Seok C, Qin S, Zhou HX, Ritchie DW, Maigret B, Devignes MD, Ghoorah A, Torchala M, Chaleil RA, Bates PA, Ben-Zeev E, Eisenstein M, Negi SS, Weng Z, Vreven T, Pierce BG, Borrman TM, Yu J, Ochsenbein F, Guerois R, Vangone A, Rodrigues JP, van Zundert G, Nellen M, Xue L, Karaca E, Melquiond AS, Visscher K, Kastritis PL, Bonvin AM, Xu X, Qiu L, Yan C, Li J, Ma Z, Cheng J, Zou X, Shen Y, Peterson LX, Kim HR, Roy A, Han X, Esquivel-Rodriguez J, Kihara D, Yu X, Bruce NJ, Fuller JC, Wade RC, Anishchenko I, Kundrotas PJ, Vakser IA, Imai K, Yamada K, Oda T, Nakamura T, Tomii K, Pallara C, Romero-Durana M, Jiménez-García B, Moal IH, Férnandez-Recio J, Joung JY, Kim JY, Joo K, Lee J, Kozakov D, Vajda S, Mottarella S, Hall DR, Beglov D, Mamonov A, Xia B, Bohnuud T, Del Carpio CA, Ichiishi E, Marze N, Kuroda D, Roy Burman SS, Gray JJ, Chermak E, Cavallo L, Oliva R, Tovchigrechko A, Wodak SJ
Proteins 84 (S1) 323-348 2016
DOI: 10.1002/prot.25007
ISSN: 0887-3585
eISSN: 1097-0134
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Systematic exploration of an efficient amino acid substitution matrix: MIQS International-journal Peer-reviewed
Tomii K, Yamada K
Methods in Molecular Biology 2016
DOI: 10.1007/978-1-4939-3572-7_11
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A new genotype of bovine leukemia virus in South America identified by NGS-based whole genome sequencing and molecular evolutionary genetic analysis International-journal International-coauthorship Peer-reviewed
Polat M, Takeshima SN, Hosomichi K, Kim J, Miyasaka T, Yamada K, Arainga M, Murakami T, Matsumoto Y, de la Barra Diaz V, Panei CJ, González ET, Kanemaki M, Onuma M, Giovambattista G, Aida Y
Retrovirology 13 2016
DOI: 10.1186/s12977-016-0239-z
eISSN: 1742-4690
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Refinement of Amino Acid Substitution Matrix for Detecting Distant Relationships of Proteins Peer-reviewed
Yamada K, Tomii K
Seibutsu Butsuri 55 (3) 133-136 2015
ISSN: 0582-4052
eISSN: 1347-4219
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A novel antiviral target structure involved in the RNA binding, dimerization, and nuclear export functions of the influenza A virus nucleoprotein International-journal Peer-reviewed
Kakisaka M, Sasaki Y, Yamada K, Kondoh Y, Hikono H, Osada H, Tomii K, Saito T, Aida Y
PLOS Pathogens 11 (7) e1005062 2015
DOI: 10.1371/journal.ppat.1005062
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PoSSuM v.2.0: data update and a new function for investigating ligand analogs and target proteins of small-molecule drugs International-journal Peer-reviewed
Ito JI, Ikeda K, Yamada K, Mizuguchi K, Tomii K
Nucleic Acids Research (NAR) 2015
DOI: 10.1093/nar/gku1144
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Comparative analysis of seven viral nuclear export signals (NESs) reveals the crucial role of nuclear export mediated by the third NES consensus sequence of nucleoprotein (NP) in influenza A virus replication International-journal Peer-reviewed
Chutiwitoonchai N, Kakisaka M, Yamada K, Aida Y
PLOS ONE 9 (8) e105081 2014
DOI: 10.1371/journal.pone.0105081
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Revisiting amino acid substitution matrices for identifying distantly related proteins International-journal Peer-reviewed
Yamada K, Tomii K
Bioinformatics 2014
DOI: 10.1093/bioinformatics/btt694
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Importin α3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport function International-journal Peer-reviewed
Sasaki Y, Hagiwara K, Kakisaka M, Yamada K, Murakami T, Aida Y
PLOS ONE 8 (1) e55765 2013
DOI: 10.1371/journal.pone.0055765
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Identification of a novel compound with antiviral activity against influenza A virus depending on PA subunit of viral RNA polymerase International-journal Peer-reviewed
Yamada K, Koyama H, Hagiwara K, Ueda A, Sasaki Y, Kanesashi SN, Ueno R, Nakamura HK, Kuwata K, Shimizu K, Suzuki M, Aida Y
Microbes and Infection 14 (9) 740-7 2012
DOI: 10.1016/j.micinf.2012.02.012
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Discovery of novel antiviral agents directed against the influenza A virus nucleoprotein using photo-cross-linked chemical arrays International-journal Peer-reviewed
Hagiwara K, Kondoh Y, Ueda A, Yamada K, Goto H, Watanabe T, Nakata T, Osada H, Aida Y
Biochemical and Biophysical Research Communications 394 (3) 721-7 2010
DOI: 10.1016/j.bbrc.2010.03.058
Research Projects 5
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医用システム開発をモデルとする“ニューロ”・ジェンダード・イノベーションの提案
菊池洋平, 佐々木成江, 濱本裕美, 山田和範
System: 科学研究費補助金:挑戦的研究(萌芽)
2026 - 2028
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機械学習を用いた組合せ構造の構成への試み
原田昌晃, 山田和範, 新谷誠
System: 科学研究費補助金:挑戦的研究(萌芽)
2025 - 2027
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効率的な分解誘導薬創成に向けた分子設計AIの基盤開発
富井健太郎, 椿真史, 池田修巳, 山田和範
System: NEDO先導研究プログラム
2023 - 2024
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人工知能で目指すアミノ酸配列類似性検索法の高速化および高感度化研究 Competitive
山田和範
System: 科学研究費補助金:若手研究
2018 - 2020
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MAFFT多重アラインメントプログラムの大量配列データへの対応と機能拡張 Competitive
加藤和貴, 山田和範, 富井健太郎
System: 科学研究費補助金:基盤研究C
2016 - 2020
https://orcid.org/0000-0001-7218-6148