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博士(理学)(東京工業大学)
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修士(化学)(工学院大学)
Details of the Researcher
Research Interests 2
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natural product synthesis
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organic synthesis
Research Areas 1
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Nanotechnology/Materials / Synthetic organic chemistry /
Awards 4
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第一三共 研究企画賞
2020/12 公益社団法人 有機合成化学協会 福山カップリングの新展開:ワンポット連続カップリングによる1, 3-ジケトン合成法の開発と複雑天然物の全合成
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第62回天然有機化合物討論会奨励賞
2020/10
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日本薬学会東北支部奨励賞
2020/10
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ISAT-Special ポスター賞
2012/10 Synthetic study on naphthospironone A
Papers 19
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Synthesis of 2-Phosphorus-Substituted Indoles via Ring Expansion of Benzocyclobutenone Oxime Sulfonates
Yusuke Kanno, Yumi Yamashita, Akira Sugiyama, Tatsuhiko Kodama, Juri Sakata, Hidetoshi Tokuyama
Organic Letters 2025/05/29
Publisher: American Chemical Society (ACS)DOI: 10.1021/acs.orglett.5c01778
ISSN: 1523-7060
eISSN: 1523-7052
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ジテルペンアルカロイド Acochlearineの合成研究
河野 駿, 宮本 尚也, 藤岡 孝佑, 坂田 樹理, 徳山 英利
第63回天然有機化合物討論会講演要旨集 2024/10
DOI: 10.24496/tennenyuki.63.0_13-17
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Semisynthetic Studies Establish a Role for Conjugate Halide Exchange in the Formation of Chlorinated Pyrroloiminoquinones and Related Alkaloids
Samuele Sala, Masashi Shimomura, Louisa Tham, Juri Sakata, Alexandre N. Sobolev, Stephen A. Moggach, Jane Fromont, Oliver Gomez, Matthew J. Piggott, Hidetoshi Tokuyama, Scott G. Stewart, Gavin R. Flematti
Journal of Natural Products 2024/09/30
Publisher: American Chemical Society (ACS)DOI: 10.1021/acs.jnatprod.4c00549
ISSN: 0163-3864
eISSN: 1520-6025
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オキシムスルホナートの環拡大反応を利用したインドール合成法を基盤とする(+)-CC-1065、isobatzelline A/B、batzelline Aの全合成
第62回天然有機化合物討論会講演要旨集 2023/10
DOI: 10.24496/tennenyuki.62.0_163-168
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Antibody-mimetic drug conjugate with efficient internalization activity using anti-HER2 VHH and duocarmycin
Juri Sakata, Toshifumi Tatsumi, Akira Sugiyama, Akihiro Shimizu, Yuya Inagaki, Hiroto Katoh, Takefumi Yamashita, Kazuki Takahashi, Sho Aki, Yudai Kaneko, Takeshi Kawamura, Mai Miura, Masazumi Ishii, Tsuyoshi Osawa, Toshiya Tanaka, Shumpei Ishikawa, Masanobu Tsukagoshi, Michael Chansler, Tatsuhiko Kodama, Motomu Kanai, Hidetoshi Tokuyama, Kenzo Yamatsugu
Protein Expression and Purification 106375-106375 2023/10
Publisher: Elsevier BVDOI: 10.1016/j.pep.2023.106375
ISSN: 1046-5928
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Unified Divergent Total Synthesis of Discorhabdin B, H, K, and Aleutianamine via the Late-Stage Oxidative N,S-Acetal Formation Peer-reviewed
Masashi Shimomura, Kohta Ide, Juri Sakata, Hidetoshi Tokuyama
Journal of the American Chemical Society 145 (33) 18233-18239 2023/08/09
DOI: 10.1021/jacs.3c06578
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Construction of Tetrahydroquinolines with Spirocyclic Structures at the 4-Position Peer-reviewed
Yuko Wakahara, Takahiro Noro, Juri Sakata, Hirofumi Ueda, Hidetoshi Tokuyama
Heterocycles 2022/03
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Synthetic Studies on Complex Natural Products Based on Development of a Novel Synthetic Method for Heteroaromatic Skeleton
Juri Sakata
YAKUGAKU ZASSHI 142 (2) 91-100 2022/02/01
Publisher: Pharmaceutical Society of JapanISSN: 0031-6903
eISSN: 1347-5231
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Synthetic studies on discorhabdin V: Construction of the A–F hexacyclic framework
Takahiro Noro, Juri Sakata, Hidetoshi Tokuyama
Tetrahedron Letters 81 153333-153333 2021/09
Publisher: Elsevier BVDOI: 10.1016/j.tetlet.2021.153333
ISSN: 0040-4039
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Cyclic Sulfamidite as Simultaneous Protecting Group for Amino Alcohols: Development of a Mild Deprotection Protocol Using Thiophenol Peer-reviewed
Juri Sakata, Kazunari Akita, Manabu Sato, Masashi Shimomura, Hidetoshi Tokuyama
Chemical and Pharmaceutical Bulletin 68 (10) 996-1000 2020/10/01
Publisher: Pharmaceutical Society of JapanISSN: 0009-2363
eISSN: 1347-5223
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Total syntheses of (–)-emestrin H and (–)-asteroxepin Peer-reviewed
Kanato Umeki, Yusuke Ueda, Juri Sakata, Hidetoshi Tokuyama
Tetrahedron 131630-131630 2020/10
Publisher: Elsevier BVDOI: 10.1016/j.tet.2020.131630
ISSN: 0040-4020
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Divergent Total Syntheses of Isobatzellines A/B and Batzelline A Peer-reviewed
Yumi Yamashita, Louna Poignant, Juri Sakata, Hidetoshi Tokuyama
Organic Letters 2020/07/05
Publisher: American Chemical Society (ACS)DOI: 10.1021/acs.orglett.0c01894
ISSN: 1523-7060
eISSN: 1523-7052
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Total Synthesis of (–)-Lepadiformine A via Radical Translocation–Cyclization Reaction Peer-reviewed
M. Shimomura, M. Sato, H. Azuma, J. Sakata, H. Tokuyama
Organic Letters 2020
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Fluorescent Labeling Method Re-Evaluates the Intriguing Thermoresponsive Behavior of Poly(acrylamide-co-acrylonitrile)s with Upper Critical Solution Temperatures Peer-reviewed
Otsuka Chie, Wakahara Yuko, Okabe Kohki, Sakata Juri, Okuyama Masaki, Hayashi Akinobu, Tokuyama Hidetoshi, Uchiyama Seiichi
MACROMOLECULES 52 (20) 7646-7660 2019/10/22
DOI: 10.1021/acs.macromol.9b00880
ISSN: 0024-9297
eISSN: 1520-5835
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Total Synthesis of (+)-CC-1065 Utilizing Ring Expansion Reaction of Benzocyclobutenone Oxime Sulfonate Peer-reviewed
Taku Imaizumi, Yumi Yamashita, Yuki Nakazawa, Kentaro Okano, Juri Sakata, Hidetoshi Tokuyama
Organic Letters 21 (16) 6185-6189 2019/08/16
DOI: 10.1021/acs.orglett.9b01690
ISSN: 1523-7060
eISSN: 1523-7052
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Synthetic Studies on Plakinidines Peer-reviewed
T. Satoh , T. Adachi , K. Okano , J. Sakata , H. Tokuyama
Heterocycles 99 310-323 2019
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One-Pot Reductive Allylation of Amides by Using a Combination of Titanium Hydride and an Allylzinc Reagent: Application to a Total Synthesis of (-)-Castoramine Peer-reviewed
Itabashi Suguru, Shimomura Masashi, Sato Manabu, Azuma Hiroki, Okano Kentaro, Sakata Juri, Tokuyama Hidetoshi
SYNLETT 29 (13) 1786-1790 2018/08
ISSN: 0936-5214
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Structural Determination of (-)-SCH 64874 and Hirsutellomycin by Semisynthesis Peer-reviewed
Hidetoshi Tokuyama, Kaori Yamada, Hideto Fujiwara, Juri Sakata, Kentaro Okano, Malipan Sappan, Masahiko Isaka
JOURNAL OF ORGANIC CHEMISTRY 82 (1) 353-371 2017/01
ISSN: 0022-3263
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Synthetic Study on Naphthospironone A: Construction of Benzobicyclo[3.2.1]octene Skeleton with Oxaspirocycle Peer-reviewed
Juri Sakata, Yoshio Ando, Ken Ohmori, Keisuke Suzuki
ORGANIC LETTERS 17 (15) 3746-3749 2015/08
DOI: 10.1021/acs.orglett.5b01732
ISSN: 1523-7060
eISSN: 1523-7052
Misc. 4
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The Asymmetric Total Synthesis of Discorhabdin B, H, K, and Aleutianamine
Juri Sakata, Masashi Shimomura, Hidetoshi Tokuyama
Modern Natural Product Synthesis 103-125 2024/05/28
Publisher: Springer Nature SingaporeDOI: 10.1007/978-981-97-1619-7_5
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Recent Progress on the Total Synthesis of Duocarmycins A and SA, Yatakemycin, and PDE-I and PDE-II
Juri Sakata, Hidetoshi Tokuyama
Cutting-Edge Organic Synthesis and Chemical Biology of Bioactive Molecules 101-124 2019/05/31
Publisher: Springer SingaporeDOI: 10.1007/978-981-13-6244-6_5
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迅速骨格構築と合成終盤のC-H酸化が可能にするアコニチンの短段階全合成—Synthetic studies on aconitine : development of a novel strategies for highly oxiganated polycyclic flamework—平成29年度研究奨励金受領報告 ; 研究奨励金 ; 創薬の基礎となる新しい分子設計・合成化学
坂田 樹理
東京生化学研究会助成研究報告集 33 99-103 2018
Publisher: 東京 : 東京生化学研究会ISSN: 1345-4927
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ひずみエネルギーの解消を駆動力とするアミノ化反応
坂田 樹理
ファルマシア 52 (12) 1154-1154 2016
Publisher: 公益社団法人 日本薬学会DOI: 10.14894/faruawpsj.52.12_1154
ISSN: 0014-8601
eISSN: 2189-7026
Books and Other Publications 1
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Cutting-edge organic synthesis and chemical biology of bioactive molecules : the shape of organic synthesis to come
Kobayashi, Yuichi
Springer 2019
ISBN: 9789811362439
Industrial Property Rights 1
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VHH抗体とストレプトアビジン変異体との融合タンパク質
田中 十志也, 児玉 龍彦, 金井 求, 山次 健三, 巽 俊文, 杉山 暁, 塚越 雅信, 中井 正矩, マイケル・チャンスラー, 徳山 英利, 坂田 樹理
Property Type: Patent
Research Projects 4
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硫黄含有複雑天然物の化学合成に立脚して展開する創薬研究
坂田 樹理
Offer Organization: 日本学術振興会
System: 科学研究費助成事業
Category: 基盤研究(C)
Institution: 東北大学
2024/04 - 2027/03
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革新的インドール合成法の開発、全合成を基盤に展開する多角的な創薬研究
坂田 樹理
Offer Organization: 日本学術振興会
System: 科学研究費助成事業
Category: 若手研究
Institution: 東北大学
2021/04/01 - 2024/03/31
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Creation of Next Generation Antibody Drug Conjugate Therapeutics for Advanced Cancer
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research
Category: Grant-in-Aid for Scientific Research (B)
Institution: The University of Tokyo
2021/04/01 - 2024/03/31
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Synthetic studies on complex natural products based on development of a novel indole synthesis
Sakata Juri
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research
Category: Grant-in-Aid for Early-Career Scientists
Institution: Tohoku University
2018/04/01 - 2021/03/31