東北大学研究者紹介

経歴 6

2025年4月～継続中

東北大学　変動海洋エコシステム高等研究所　特任研究員
2024年7月～ 2025年4月

東北大学　大学院生命科学研究科　助教
2024年4月～ 2024年6月

東京大学　新領域創成科学研究科先端生命科学専攻　特任研究員
2022年4月～ 2024年4月

独立行政法人日本学術振興会, 特別研究員 DC2
2020年10月～ 2021年3月

東京大学新領域創成科学研究科, 研究生
2019年10月～ 2020年8月

東北師範大学中国赴日本国留学生予備学校

︎全件表示 ︎最初の5件までを表示

学歴 3

東京大学　大学院新領域創成科学研究科

2021年4月～ 2024年3月
中国科学院大学

2015年9月～ 2018年6月
集美大学

2011年9月～ 2015年6月

所属学協会 2

日本地球惑星科学連合

2026年4月～継続中
環境DNA学会

2022年9月～継続中

研究分野 4

自然科学一般 / 大気水圏科学 / 気候変動；温暖化
ライフサイエンス / 分子生物学 / CRISPR-Cas検出
ライフサイエンス / 水圏生命科学 / メタゲノム
環境・農学 / 生物資源保全学 / 環境DNA; 環境RNA

受賞 5

最優秀学生ポスター賞

2023年5月　環境DNA学会　Environmental mRNA-seq of Xenopus laevis and Gasterosteus aculeatus
Travel Grant (AUD 750)

2023年2月　1st Australian & New Zealand Environmental DNA Conference, Hobart, Australia, 2023
文部科学省国費留学生

2019年10月
Liu Ruiyu Marine Science Scholarship

2018年8月　University of Chinese Academy of Sciences
Travel Grant (600 USD)

2017年10月　22nd Biennial Conference on the Biology of Marine Mammals, Halifax, Canada, 2017

論文 8

The Grand Challenges of WPI-AIMEC: Executive Summary

Toshio Suga, Fumio Inagaki, Kentaro Ando, Michio Kondoh, S. Smith, Keith Rodgers, Toyonobu Fujii, Michio Kawamiya, Hanani Adiwira, Maki Aita, Vani Alviani, Cheryl Ames, Kamrum Azad, Ettore Barbieri, Batdulam Battulga, Jonathan Derot, Diego Deville, Tetsuichi Fujiki, Jimena García-Rodríguez, Tomoko Hamabata, Masumi Hasegawa-Takano, Andrew Hirzel, Tatsuhiko Hoshino, Benjamin Horton, Shigeki Hosoda, Minoru Ikeda, Yasufumi Iryu, Yoichi Ishikawa, Kota Ishikawa, Sabine Kasten, Jamie Kass, Satoshi Katayama, Shinya Kouketsu, Gaku Kumano, Zhen Lin, Jutarak Luang‑on, Hiroshi Murakami, Yuriko Nagano, Takashi Nakagawara, Tomoe Nasuno, Goh Nishitani, Riko Oki, Takeshi Obayashi, Yuichi Okayama, Yusaku Ohta, Shuhei Ono, Yutaka Osada, Bo Qiu, Namal Rathnayake, Kelvin Richards, Niklas Schneider, Takashi Sakamaki, Yusuke Sasaki, Kanako Sato, Masahito Shigemitsu, Eko Siswanto, Kugako Sugimoto, Shusaku Sugimoto, Yoshihisa Suyama, Kaoru Tachiiri, Hiromi Takahata, Hideko Takayanagi, Akifumi Tanabe, Hiroaki Tatebe, Fumiaki Tomita, Tsunaki Iida, Gerlien Verhaegen, Clara Vives, Lael Wakamatsu, Shingo Watanabe, Shuya Wang, Angelicque White, Nadine Wood, Baolan Wu, Shang-Ping Xie, Sayaka Yasunaka, Jiwei Yang, Akinori Yabuki, Yosuke Yamada, Alan Yee, Taichi Yokokawa, Nan Yuan, William McDonough, Kimio Hanawa

2025年8月16日
出版者・発行元： California Digital Library (CDL)
DOI： 10.31223/x55r0j 　

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The ocean has a heat capacity 1,000 times greater than that of the atmosphere and stores 50 times more carbon comparatively, thus, constituting a major sink of anthropogenically released greenhouse gases. Warming effects of human activities on the climate system are now undeniably shown to impact marine life and ecosystems, both directly via warming of the ocean and/or indirectly altering ocean circulation across spatiotemporal scales. Beyond the effect of warming on individual organisms, a changing climate signal has been argued from modeling studies to cause a ripple effect known as trophic level amplification, resulting in changes in the balance of biomass in different size classes. Larger fractional changes in biomass are expected of predator organisms at higher trophic levels, such as fish, due to shifts in the representative phytoplankton at the base of the food web. With a shift towards smaller phytoplankton, trophic amplification scenarios are expected to disrupt fisheries and carbon storage algorithms and negatively affect ecosystem services necessary for a sustainable society. Despite continued advances in monitoring and modeling of ecosystems projecting changes related to trophic coupling, suitable habitat and biogeochemical element cycling remains difficult due to inadequate information on marine ecosystems across spatiotemporal scales. WPI-Advanced Institute for Marine Ecosystem Change (WPI-AIMEC) operates based on five institutional Grand Challenges (GCs). These GCs aim to promote fusion science by integrating observational, analytical, and modeling tools to complement theoretical approaches and advance our understanding of the processes driving marine ecosystem change. By combining the research skills and knowledge of the host institutes Tohoku University and Japan Agency for Marine-Earth Science and Technology (JAMSTEC) in partnership with University ofHawai'i, we seek transformative solutions to the grandest challenges of addressing marine ecosystem change through diverse perspectives encompassing marine physics, biology, ecology, biogeochemistry, and data science. Overall, the AIMEC Grand Challenges offer unprecedented opportunities for crossdisciplinary fusion science and scientific breakthroughs with the attainable goal of "Planetary Stewardship”—the responsible management and care of the natural systems to ensure a sustainable and healthy planet for future generations.
Rapid, easy, sensitive, low‐cost and on‐site detection of environmental DNA and RNA using CRISPR‐Cas13

Jiwei Yang, Shoma Matsushita, Fei Xia, Susumu Yoshizawa, Wataru Iwasaki

Methods in Ecology and Evolution　2024年7月9日
出版者・発行元： Wiley
DOI： 10.1111/2041-210x.14369 　

ISSN：2041-210X

eISSN：2041-210X

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Abstract Environmental DNA (eDNA) monitoring of species distribution has become a critical tool in ecology, conservation biology and fisheries for identifying the presence and distribution of diverse organisms, including important, threatened and invasive species. However, eDNA detection still has room for improvement in sensitivity, requiring time‐consuming real‐time polymerase chain reaction (qPCR) steps and costly machines. In this study, we report a CRISPR‐Cas13‐based method for rapid, easy, sensitive, low‐cost and on‐site detection of eDNA. The assay for the detection of common carp (Cyprinus carpio) and medaka (Oryzias latipes) nucleic acid employs a two‐step process, starting with recombinase polymerase amplification (RPA) and followed by cleavage using Cas13 nuclease, to effectively identify mitochondrial DNA or RNA. Our results showed that the Cas13‐based method has a higher sensitivity than the qPCR‐based method in detecting tiny amounts of eDNA. When combined with reverse transcription of environmental RNA (eRNA), our method increased detection sensitivity by approximately one order of magnitude. Cas13‐based detection could achieve on‐site detection of eDNA using a quick nucleic acid extraction solution and lateral flow strips. Cas13‐based detection of eDNA and eRNA requires minimal training efforts and can be performed in 1 h, without the need for centrifugation and qPCR machines. The portability of the Cas13‐based method, along with its accuracy and relative ease in designing primers and CRISPR RNA (crRNA), underscores its potential to broaden the application of eDNA and eRNA in various fields, including biodiversity conservation.
Cover Image

Jiwei Yang, Kang Wang, Zhigang Mei, Jun Xu, Jinsong Zheng, Xiaoling Wan, Yujiang Hao, Kexiong Wang, Ding Wang

Freshwater Biology　2021年5月

DOI： 10.1111/fwb.13546 　
Temporal variation in the diet of Yangtze finless porpoise calls for conservation of semi‐migratory fish

Jiwei Yang, Kang Wang, Zhigang Mei, Jun Xu, Jinsong Zheng, Xiaoling Wan, Yujiang Hao, Kexiong Wang, Ding Wang

Freshwater Biology　2021年5月

DOI： 10.1111/fwb.13692 　
A preliminary study on diet of the Yangtze finless porpoise using next‐generation sequencing techniques

Jiwei Yang, Xiaoling Wan, Xianyuan Zeng, Jinsong Zheng, Yi Han, Fei Fan, Yujiang Hao, Kexiong Wang, Zhigang Mei, Ding Wang

Marine Mammal Science　2019年10月

DOI： 10.1111/mms.12585 　
Hormonal Regulation of Testicular Development in the Finless Porpoise Neophocaena asiaeorientalis sunameri: Preliminary Evidence from Testicular Histology and Immunohistochemistry

Yang Xiao, Ghulam Nabi, Jiwei Yang, Yujiang Hao, and Ding Wang

Zoological Studies　2018年9月
Characterization of milk protein composition of the Yangtze finless porpoise

Xianyuan Zeng, Minmin Chen, Zhigang Liu, Daoping Yu, Shiang‐Lin Huang, Jiwei Yang, Fei Fan, Ding Wang, Yujiang Hao, Ghulam Nabi

Marine Mammal Science　35　(1)　252-260　2018年4月26日
出版者・発行元： Wiley
DOI： 10.1111/mms.12508 　

ISSN：0824-0469

eISSN：1748-7692
Parasitic infections in the East Asian finless porpoise Neophocaena asiaeorientalis sunameri living off the Chinese Yellow/Bohai Sea coast

XL Wan, JS Zheng, WX Li, XY Zeng, JW Yang, YJ Hao, D Wang

Diseases of Aquatic Organisms　125　(1)　63-71　2017年6月19日
出版者・発行元： Inter-Research Science Center
DOI： 10.3354/dao03131 　

ISSN：0177-5103

eISSN：1616-1580

︎全件表示 ︎最初の5件までを表示

講演・口頭発表等 13

ANEMONEから学ぶ大規模eDNA群集解析の基礎と実践

YANG JIWEI

2026年6月8日
Tightly packed isotherms constrain temporal turnover in marine biodiversity 招待有り

Jiwei Yang, Michio Kondoh

2026年5月28日
Asymmetric ocean warming is slowing the temporal turnover of marine biodiversity

JIWEI YANG

第73回日本生態学会大会　2026年3月12日
Thermal traps constrain community reorganization under global warming

JIWEI YANG, Michio Kondoh

第8回環境DNA学会山口大会　2025年12月11日
Thermal traps constrain temporal turnover in biodiversity

YANG JIWEI

OIST x WPI-AIMEC (Tohoku U & JAMSTEC) Joint Workshop　2025年11月20日
Tracking climate impacts on Kuroshio marine fish communities using environmental DNA

Jiwei Yang, Michio Kondoh

Pan-CLIVAR Meeting 2025　2025年9月24日
Tracking climate impacts on Kuroshio marine fish communities using environmental DNA

Jiwei Yang, Michio Kondoh

The 11th EAFES International Congress　2025年7月21日
CRISPR-Cas13による環境DNA検出

楊積偉

The eDNA Society International Meeting 2023　2023年5月18日
Environmental mRNA-seq of Xenopus laevis and Gasterosteus aculeatus

Fei Xia, Jiwei Yang, Yuanyu Wang, Yihan Ma, Susumu Yoshizawa, Asano Ishikawa, Hiroki Kuroda, Wataru Iwasaki

The eDNA Society International Meeting 2023　2023年5月17日
コイ核及びミトコンドリア環境DNA濃度の終日モニタリング

Fei Xia, Jiwei Yang, Hiroki Kuroda, Wataru Iwasaki

あなたが主役のワークショップ　2022年11月19日
Rapid environmental DNA detection by CRISPR-Cas13

楊積偉, 岩崎渉

Tokyo Bioinformatics Meeting　2022年10月15日
CRISPR-Cas13による環境DNA検出

楊積偉, 松下翔真, 夏非, 吉澤晋, 岩崎渉

1st Australian & New Zealand eDNA Conference　2023年2月17日
A preliminary study on diet of the Yangtze finless porpoise using next-generation sequencing techniques

Yang J, Wan X, Zeng X, Zheng J, Mei Z, Wang D

22nd Biennial Conference on the Biology of Marine Mammals　2017年10月24日

︎全件表示 ︎最初の5件までを表示

共同研究・競争的資金等の研究課題 1

環境RNAのオンサイト検出法の開発と内部標準RNAによる絶対定量

YANG Jiwei

提供機関：Japan Society for the Promotion of Science

制度名：Grants-in-Aid for Scientific Research

研究種目：Grant-in-Aid for JSPS Fellows

研究機関：The University of Tokyo

2023年3月8日～ 2024年3月31日

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We have achieved faster and more sensitive detection than real-time PCR (qPCR) using a new CRISPR-based detection technology for the first part of the rapid detection of environmental DNA and RNA. We examined samples of the same environmental DNA using the designed CRISPR and qPCR primers for Cyprinus carpio separately and showed that CRISPR possessed higher sensitivity than the qPCR method. Additionally, by adding reverse transcriptase, we can simultaneously detect environmental DNA and RNA, improving the detection sensitivity by approximately one order of magnitude. Finally, we have achieved a fully field-based, one-hour detection process from filtration to nucleic acid extraction and final readouts, which has been tested for the detection of environmental DNA and environmental RNA from several marine and freshwater fish species. These results have been summarized and submitted for peer-review. We plan to further optimize this method by reducing reaction time, achieving quantitative detection, and simplifying the operation steps to enable non-professionals to use environmental DNA and RNA for species detection.