研究者詳細

顔写真

ヨシダ　シンイチロウ
吉田　新一郎
Shinichirou Yoshida
所属
病院　外科　整形外科
職名
助教
学位

  • 医学博士 （東北大学）

研究分野 1

  • ライフサイエンス / 整形外科学 /

受賞 1

  1. 優秀演題賞

    2012年1月　第23回東北脊椎外科研究会　最近10年の当科におけるLiqueSSI法の経験

論文 68

  1. Case Report: Xanthogranulomatous Osteomyelitis of the Femur: A Rare Mimic of Malignant Bone Tumors. 国際誌

    Hiroshi Hatakeyama, Yu Mori, Shinichirou Yoshida, Jun Iwatsu, Hirotaka Kurata, Shin Hitachi, Mika Watanabe, Toshimi Aizawa

    International journal of rheumatic diseases　28　(6)　e70313　2025年6月

    DOI： 10.1111/1756-185X.70313 　

  2. Trigger Finger Caused by a Solitary Osteochondroma of the Proximal Phalanx in an Adolescent: A Case Report. 国際誌

    Hirotaka Kurata, Michiyuki Hakozaki, Shinichirou Yoshida, Jun Iwatsu, Toshitake Aizawa

    Cureus　17　(2)　e79691　2025年2月

    DOI： 10.7759/cureus.79691 　

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    Trigger finger is a common disease, and stenosing tenosynovitis is the most frequent cause of this condition in middle-aged women. We report a case of surgical excision in a 16-year-old adolescent male with trigger finger symptoms caused by a solitary osteochondroma at the proximal end of the proximal phalanx. Although tumorous lesions are a rare cause of trigger finger, a differential diagnosis is necessary because the treatment strategy and surgical technique employed to treat this condition differ from those employed for common causes, such as stenosing tenosynovitis and pediatric trigger thumb.

  3. Association Between Sleep Disturbance and Low Back Pain: A 3-year Longitudinal Study After the Great East Japan Earthquake. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Ichiro Tsuji

    Spine　2024年10月8日

    DOI： 10.1097/BRS.0000000000005176 　

  4. Assessment of clinical and radiological characteristics of Japanese patients with SAPHO syndrome

    Yu Mori, Takuya Izumiyama, Hiroshi Okuno, Munenori Watanuki, Ryuichi Kanabuchi, Shinichiro Yoshida, Jun Iwatsu, Naoko Mori, Toshimi Aizawa

    Modern Rheumatology　2023年8月24日

    出版者・発行元： Oxford University Press (OUP)

    DOI： 10.1093/mr/road086 　

    ISSN：1439-7595

    eISSN：1439-7609

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    Abstract Objective This study aimed to analyse the radiological characteristics and clinical diversity of Japanese patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a heterogeneous disorder. Methods Radiographs and clinical information from 115 Japanese patients (female/male: 81/34, mean age at onset: 48.7 years) diagnosed with SAPHO syndrome between January 2007 and December 2020 were retrospectively reviewed. Additionally, the treatment for SAPHO syndrome was explored. Results Among the 115 patients, 70 patients had complications, including palmoplantar pustulosis, acne, or psoriasis. Imaging studies included bone scintigraphy, magnetic resonance imaging, computed tomography, and positron emission tomography in 71, 58, 70, and 23 patients, respectively. The most frequent lesions were arthritis and hyperostosis of the sternoclavicular joints in 96 patients; spinal lesions, including sacroiliac arthritis were observed in 85 patients. Peripheral aseptic osteitis was observed in 22 patients, and the tibia was involved in 12. The treatments consisted of analgesics, bisphosphonates, conventional synthetic disease-modifying anti-rheumatic drugs, and biologics (tumour necrosis factor inhibitors and interleukin-23p19 inhibitors) in 85, 15, 23, and 10 patients (8 and 2 patients), respectively. Conclusion Sternoclavicular hyperostosis and pustulosis are frequently observed in patients with SAPHO syndrome. Biological agents were more frequently used in patients with peripheral osteitis and arthritis.

  5. 凍結肩の関節包におけるインフラマソーム活性化の関与

    高橋 正樹, 萩原 嘉廣, 矢部 裕, 関口 拓矢, 吉田 新一郎, 相澤 俊峰

    日本整形外科学会雑誌　97　(8)　S1918-S1918　2023年8月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

    eISSN：2758-7479

  6. 関節鏡視下に切除を行った上腕骨頭発生類骨骨腫の一例

    有野 敦司, 吉田 新一郎, 岩津 潤, 綿貫 宗則, 山本 宣幸, 相澤 俊峰, 常陸 真, 渡邉 みか

    東北整形災害外科学会雑誌　66　(1)　166-167　2023年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN：1348-8694

  7. SAPHO症候群の放射線学的特徴と臨床的多様性の検討

    森 優, 泉山 拓也, 綿貫 宗則, 吉田 新一郎, 森 菜緒子, 相澤 俊峰

    日本整形外科学会雑誌　97　(3)　S888-S888　2023年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

  8. SAPHO症候群の放射線学的特徴と臨床的多様性の検討

    森 優, 泉山 拓也, 綿貫 宗則, 吉田 新一郎, 森 菜緒子, 相澤 俊峰

    日本整形外科学会雑誌　97　(3)　S888-S888　2023年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

  9. Knee pain in young sports players aged 6-15 years: a cross-sectional study in Japan. 国際誌

    Jun Iwatsu, Yutaka Yabe, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Shinichirou Yoshida, Yasuhito Sogi, Ryoichi Nagatomi, Yoshihiro Hagiwara

    BMC sports science, medicine & rehabilitation　15　(1)　16-16　2023年2月7日

    DOI： 10.1186/s13102-022-00606-y 　

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    BACKGROUND: Knee is the most commonly injured part of the body in young athletes. Knee pain in several studies have been seen to be more prevalent in active adolescents compared to inactive, although common in both groups. Nevertheless, few studies with large sample size have been published reporting the difference of the prevalence of knee pain for each sport among young sports players. This study investigated the point prevalence of knee pain among young sports players aged 6-15 years old according to age, sex, and sports discipline. Furthermore, this study investigated the association between knee pain and sports discipline among young sports players. METHODS: A cross-sectional study was conducted using a self-reported questionnaire on young sports players aged 6-15 years from the Miyagi Amateur Sports Association. Multivariable logistic regression models were used to examine the association between knee pain and sports discipline and were adjusted for age, sex, body mass index (BMI), training days per week, and training hours per weekday and weekend. RESULTS: A total of 7234 young sports players were included. The point prevalence of knee pain was 10.9%. Females (13.3%) had more knee pain than males (9.8%). Young, 13-year-old sports players had the highest prevalence of knee pain (19.1%). The multivariable analysis showed that the highest odds ratio [95% confidence interval] was observed for handball players (2.42 [1.01-5.81]). In addition, hand ball, mini-basketball (odds ratio 1.85; 95% CI 1.38-2.47), and basketball (odds ratio 1.66; 95% CI 1.23-2.26) were significantly associated with knee pain, compared with football. The lowest odds ratio was observed for swimming (0.34 [0.05-2.54]), followed by karate (odds ratio 0.38; 95% CI 0.16-0.89) and baseball (odds ratio 0.47; 95% CI 0.35-0.64). CONCLUSION: The prevalence of knee pain among young athletes differed according to age, sex, and sports discipline. Their parents and clinicians should recognize this information to manage knee pain among young sports players.

  10. Comparative proteome analysis of the ligamentum flavum of patients with lumbar spinal canal stenosis. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Masahiro Tsuchiya, Takashi Minowa, Taro Takemura, Shinya Hattori, Shinichirou Yoshida, Takahiro Onoki, Keisuke Ishikawa

    JOR spine　5　(4)　e1210　2022年12月

    DOI： 10.1002/jsp2.1210 　

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    BACKGROUND: Thickening of the ligamentum flavum is considered to be the main factor for lumbar spinal canal stenosis (LSCS). Although some mechanisms have been speculated in the thickening of the ligamentum flavum, there are only a few comprehensive approaches to investigate its pathology. The objective of this study was to investigate the pathology of thickened ligamentum flavum in patients with LSCS based on protein expression levels using shotgun proteome analysis. METHODS: Ligamentum flavum samples were collected from four patients with LSCS (LSCS group) and four patients with lumbar disc herniation (LDH) as controls (LDH group). Protein mixtures were digested and analyzed by liquid chromatography/mass spectrometry analysis. To compare protein expression levels between the LSCS and LDH groups, the mean Mascot score was compared. Biological processes were assessed using Gene Ontology analysis. RESULTS: A total of 1151 proteins were identified in some samples of ligamentum flavum. Among these, 145 proteins were detected only in the LSCS group, 315 in the LDH group, and 691 in both groups. The demonstrated biological processes occurring in the LSCS group included: extracellular matrix organization, regulation of peptidase activity, extracellular matrix disassembly, and negative regulation of cell growth. Proteins related to fibrosis, chondrometaplasia, and amyloid deposition were found highly expressed in the LSCS group compared with those in the LDH group. CONCLUSIONS: Tissue repair via fibrosis, chondrometaplasia, and amyloid deposits may be important pathologies that occur in the thickened ligamentum flavum of patients with LSCS.

  11. Sleep disturbance is associated with neck pain: a 3-year longitudinal study after the Great East Japan Earthquake. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Ichiro Tsuji

    BMC musculoskeletal disorders　23　(1)　459-459　2022年5月16日

    DOI： 10.1186/s12891-022-05410-w 　

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    BACKGROUND: Neck pain is a common health problem in the general population as well as in people after natural disasters. Sleep disturbances are gaining attention as risk factors for musculoskeletal pain; however, the association between sleep disturbance and neck pain has not been clarified. The present study aimed to clarify the association between sleep disturbance and neck pain, especially focusing on the effect of the duration of sleep disturbance, after the Great East Japan Earthquake. METHODS: This study used 3-year longitudinal data obtained from individuals (n = 2,059) living in disaster-affected areas after the Great East Japan Earthquake. Sleep disturbance and neck pain were investigated at 4, 5, 6, and 7 years after the disaster. Multivariate logistic regression analyses were used for the assessment. RESULTS: Sleep disturbance was significantly associated with neck pain, and the association was stronger as the duration of sleep disturbance increased (adjusted odds ratios [95% confidence intervals]: 1.84 [1.23-2.75] for " < 1 year"; 2.41 [1.53-3.81] for " ≥ 1 year and < 2 years"; 2.80 [2.09-3.76] for " ≥ 2 years"). Furthermore, preceding sleep disturbance was significantly associated with the onset of neck pain, and the association was stronger as the duration of sleep disturbance increased (adjusted odds ratios [95% confidence intervals]: 1.86 [1.08-3.20] for " < 1 year"; 2.39 [1.22-4.70] for " ≥ 1 year and < 2 years"; 3.00 [1.94-4.65] for " ≥ 2 years"). CONCLUSIONS: Sleep disturbance is associated with neck pain, and long-lasting sleep disturbance strengthens the association. Clinicians should consider this association to effectively treat patients with neck pain, especially those affected by natural disasters.

  12. Clinical outcome of porous hydroxyapatite/collagen graft on bone defects following curettage of bone tumors. 国際誌

    Jun Iwatsu, Munenori Watanuki, Shinichirou Yoshida, Shin Hitachi, Mika Watanabe, Toshimi Aizawa

    Journal of biomedical materials research. Part B, Applied biomaterials　110　(10)　2211-2216　2022年4月19日

    DOI： 10.1002/jbm.b.35070 　

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    Hydroxyapatite/collagen (HAp/col) has been reported to be a highly useful bone-like nanocomposite. This study included 33 human patients to investigate the details of the clinical outcomes, which are (1) onset of timing of bone regeneration, (2) replacement by regenerated bone of HAp/col and (3) complications, in human cases grafting HAp/col in large bone defects, following curettage of bone tumors. Porous HAp/col initiated bone regeneration approximately 59 days following the surgery. In 15 cases (45%), complete replacement by newly formed bone was observed 12 months after surgery. On the other hand, incomplete replacement of HAp/col at the final follow-up was observed in 13 cases (39%). In these cases, HAp/col could not be detected in the transparent area of postoperative plain radiographs owing to quick absorption; moreover, it was difficult to distinguish whether the transparent area in plain radiographs was remaining HAp/col, recurrence, or remaining tumor. In addition, larger HAp/col implantation volume (≧15 cm3 ) was associated with poorer result of complete replacement (log-rank, p = .005). Further studies are warranted for the construction of a new artificial bone graft substitute that is more quickly and surely regenerated by newly formed bone in large bone defects.

  13. Tissue accumulation of neutrophil extracellular traps mediates muscle hyperalgesia in a mouse model. 国際誌

    Kazuaki Suzuki, Masahiro Tsuchiya, Shinichirou Yoshida, Kazumi Ogawa, Weijian Chen, Makoto Kanzaki, Tadahisa Takahashi, Ryo Fujita, Yuqing Li, Yutaka Yabe, Toshimi Aizawa, Yoshihiro Hagiwara

    Scientific reports　12　(1)　4136-4136　2022年3月9日

    DOI： 10.1038/s41598-022-07916-8 　

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    Accumulation of uric acid (UA) during muscular trauma is a factor involved in the development of muscle hyperalgesia. Neutrophil extracellular traps (NETs), DNA-based reticular structures to capture UA, play a central role in the pain onset of gout attacks; however, the involvement of NETs via the elevation of local UA level in muscle hyperalgesia due to injuries from muscle overuse remains unknown. The triceps surae muscles (TSMs) in the unilateral hindlimb of mice were electrically stimulated to induce excessive muscle contraction. Mechanical withdrawal thresholds, tissue UA levels, neutrophil recruitment, and protein amount of citrullinated histone 3 (citH3), a major marker of NETs, were investigated. Furthermore, whether neutrophil depletion, extracellular DNA cleavage, and administration of the urate-lowering agent febuxostat improved muscle hyperalgesia caused by NET formation was examined. CitH3 expression upon neutrophil recruitment was significantly increased in the stimulated TSMs with increased tissue UA levels, whereas febuxostat administration improved muscle hyperalgesia with decreased citH3 and tissue UA levels, as observed in neutrophil depletion and extracellular DNA digestion. The underlying mechanism of muscle hyperalgesia associated with locally recruited neutrophils forming NETs due to increased tissue UA levels potentially plays a significant role in creating a vicious circle of muscle pain.

  14. Factors Associated with Thickening of the Ligamentum Flavum on Magnetic Resonance Imaging in Patients with Lumbar Spinal Canal Stenosis. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Masahiro Tsuchiya, Yoshito Onoda, Shinichirou Yoshida, Takahiro Onoki, Keisuke Ishikawa, Daisuke Kurosawa, Eiichi Murakami

    Spine　47　(14)　1036-1041　2022年2月4日

    DOI： 10.1097/BRS.0000000000004341 　

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    STUDY DESIGN: Experimental study of LF thickness among patients with LSCS. OBJECTIVES: To elucidate the factors associated with thickening of the LF on magnetic resonance imaging (MRI). SUMMARY OF BACKGROUND DATA: Thickening of the LF is a major contributor to LSCS. This thickening is attributed to tissue hypertrophy or buckling of the ligament, and there may be several associated factors on MRI; however, these factors remain unclear. METHODS: We studied the LF in 56 patients (a total of 106 ligaments) with LSCS, who underwent decompressive surgery; among them, 23 were receiving haemodialysis. The Pearson correlation coefficient was used to assess relationships between the thickness of the LF on MRI and the thickness of the LF tissue, age, disc height, disc degeneration, and disc level. Patients were also categorised into 2 groups based on whether they were undergoing haemodialysis, and the relationships were assessed similarly. RESULTS: Among patients with LSCS, the thickness of the LF on MRI showed a significant positive linear relationship with the thickness of the LF tissue, and no association with disc height. Except for in those receiving haemodialysis, the thickness of the LF on MRI showed a significant positive relationship with age, disc degeneration, and disc level among patients with LSCS. CONCLUSION: In patients with LSCS, thickening of the LF on MRI appears to represent tissue hypertrophy. The association between the thickness of the LF on MRI and age, disc degeneration, and disc level may indicate simultaneous alterations of spine components along with aging that was cancelled by the effects of haemodialysis.

  15. Association Between Sleep Disturbance and Low Back Pain: A 3-Year Longitudinal Study After the Great East Japan Earthquake. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Ichiro Tsuji

    Spine　47　(4)　361-368　2021年9月28日

    DOI： 10.1097/BRS.0000000000004234 　

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    STUDY DESIGN: A longitudinal study. OBJECTIVE: The aim of this study was to clarify the association between sleep disturbance and low back pain (LBP) using 3-year longitudinal data after the Great East Japan Earthquake, with a focus on the duration or frequency of sleep disturbance and the effect of sleep disturbance on LBP. SUMMARY OF BACKGROUND DATA: Sleep disturbance and LBP are common health problems in the general population and natural disaster survivors. However, a longitudinal study in this field is rare, and the association between sleep disturbance and LBP has not been clarified. METHODS: A 3-year longitudinal study was conducted among people living in disaster-stricken areas after the Great East Japan Earthquake (n = 2059). Sleep disturbance and LBP were assessed at 4, 5, 6, and 7 years after the disaster. Multiple logistic regression analysis was performed to assess the association between the duration or frequency of sleep disturbance and LBP, and the effect of preceding sleep disturbance on the onset of LBP. The χ2 test and crude and multiple logistic regression models were used in data analysis. RESULTS: The duration and frequency of sleep disturbance were significantly associated with LBP, and the effect was stronger with longer duration and increased frequency of sleep disturbance. Furthermore, the duration and frequency of preceding sleep disturbance were significantly associated with the onset of LBP, and the effect was stronger with an increase in the duration and frequency of sleep disturbance. CONCLUSIONS: Sleep disturbance is associated with LBP in a dose-dependent manner. Attention should be paid to sleep disturbance for the treatment and prevention of LBP, especially with regard to the duration and frequency of sleep disturbance.Level of Evidence: 3.

  16. Low Back Pain in Young Sports Players: A Cross-sectional Study in Japan. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Shinichirou Yoshida, Yasuhito Sogi, Takahiro Onoki, Kazuaki Suzuki, Tadahisa Takahashi, Eiji Itoi, Ryoichi Nagatomi

    Spine　46　(17)　1154-1159　2021年9月1日

    DOI： 10.1097/BRS.0000000000003978 　

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    STUDY DESIGN: A cross-sectional study. OBJECTIVE: The purpose of this large cohort study was to assess the prevalence of low back pain (LBP) among young players participating in several types of sports. SUMMARY OF BACKGROUND DATA: LBP is a significant problem among young sports players. Sport discipline among young players is thought to be associated with LBP. However, similar previous studies did not specifically analyze LBP by age and sex. METHODS: A cross-sectional study was conducted with young sports players (ages 6-15 years, n = 7277) using a self-reported questionnaire. The prevalence of LBP was assessed using the variables of age, sex, and sport discipline. RESULTS: The point prevalence of LBP among young sports players was 5.0%. The participants between 6 and 8 years' old had the lowest prevalence of LBP (0.4%-1.3%), which increased with aging and reached the highest proportion of 13.5% to 14.8% at 13 to 14 years. Furthermore, female players had significantly higher proportions of LBP than male players (8.1% vs. 3.7%). Regarding sport discipline, the prevalence of LBP was higher in basketball, handball, and volleyball. CONCLUSION: The prevalence of LBP among young sports players was different for age, sex, and sport discipline. Further studies are needed to clarify the association of sport-specific movements to LBP in each sport discipline. This may assist in developing programs or strategies for preventing LBP among young sports players.Level of Evidence: 3.

  17. 筋・筋膜痛における好中球細胞外トラップの関与

    鈴木 一瑛, 土谷 昌広, 神崎 展, 吉田 新一郎, 綿貫 宗則, 矢部 裕, 藤田 涼, 高橋 忠久, 萩原 嘉廣, 井樋 栄二, 相澤 俊峰

    日本整形外科学会雑誌　95　(8)　S1778-S1778　2021年8月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

  18. Contracted joint capsule affects labral and chondral lesions in patients with frozen shoulder. 国際誌

    Yoshihiro Hagiwara, Kenji Kanazawa, Akira Ando, Takuya Sekiguchi, Yutaka Yabe, Masaki Takahashi, Masashi Koide, Shinichirou Yoshida

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA　29　(8)　2640-2647　2021年8月

    DOI： 10.1007/s00167-021-06600-0 　

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    PURPOSE: Intra-articular pathologies, such as labral and chondral lesions, are common in patients with frozen shoulder. This study evaluated the correlations between the range of motion and labral and chondral lesions in patients with frozen shoulder and investigated their pathophysiologies. METHODS: In total, 125 individuals (53 men and 72 women) who underwent arthroscopic pan-capsular release between 2014 and 2020 were included in the study. The range of motion was measured using scapular fixation and true glenohumeral motion under general anaesthesia. The American Shoulder and Elbow Surgeons Shoulder score and the Shoulder Rating Scale score of the University of California, Los Angeles were used to compare intra-articular pathologies. RESULTS: More than 80% of patients with frozen shoulder had labral pathologies, and nearly half of them had chondral pathologies. Labral lesions extending to the anterior rim of the glenoid had a greater range of motion and the greatest total American Shoulder and Elbow Surgeons Shoulder score. More severe chondral lesions had a lesser range of motion, but presented the greatest function scores and the lowest strength scores according to the Shoulder Rating Scale of the University of California, Los Angeles. The pain scores of the American Shoulder and Elbow Surgeons Shoulder score and the Shoulder Rating Scale of the University of California, Los Angeles were not correlated with the degree of these pathologies. The traction force affected the labrum during true range of motion, and the compression force occurred on the articular cartilage during internal rotation at 90° of forward flexion during diagnostic arthroscopy. CONCLUSION: Labral and chondral lesions are common in patients with frozen shoulder. Adherence to the capsulolabral complex induced a limited range of motion and labral and chondral pathologies. Diagnostic arthroscopy with motion is an important method of reproducing the pathogenesis of intra-articular structures for patients with frozen shoulder. LEVEL OF EVIDENCE: Level III.

  19. The 5-year course of neck pain among natural disaster survivors: The association of prior neck pain with new episodes of neck pain. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Takahiro Onoki, Tadahisa Takahashi, Jun Iwatsu, Ichiro Tsuji

    Pain medicine (Malden, Mass.)　23　(4)　635-641　2021年7月27日

    DOI： 10.1093/pm/pnab233 　

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    OBJECTIVE: Neck pain is a common health problem among both the general population and natural disaster survivors. However, the long-term course of neck pain has rarely been reported. The aim of this study was to elucidate the 5-year course of neck pain among survivors of the Great East Japan Earthquake (GEJE) by assessing the association of neck pain 2 and 4 years after the disaster with that at 7 years. STUDY DESIGN: Longitudinal study. METHODS: A panel study was conducted on GEJE survivors (n = 1,821) using a self-reported questionnaire at 2 (first time point), 4 (second time point), and 7 years (third time point) after the disaster. Multivariate logistic regression analyses were performed to assess the association between prior neck pain and subsequent neck pain. RESULTS: The rates of neck pain at the first, second, and third time points were 20.7%, 21.1%, and 20.1%, respectively. Neck pain at the first time point was significantly associated with neck pain at the third time point (adjusted odds ratio [95% confidence interval]: 5.96 [4.53-7.83]). Furthermore, neck pain at the first and second time points was significantly associated with neck pain at the third time point (adjusted odds ratio [95% confidence interval]: 5.71 [4.19-7.78] for neck pain at either time point; 15.94 [10.99-23.12] for neck pain at both time points; p for trend < 0.001). CONCLUSIONS: Prior neck pain was significantly associated with neck pain 5 years later, and the effect was stronger with increase of prior neck pain episodes. Clinicians should base their selection of treatment method on an individual's history of neck pain.

  20. Delay in diagnosis of primary osteosarcoma of bone in children: Have we improved in the last 15 years and what is the impact of delay on diagnosis?

    Shinichirou Yoshida, James Celaire, Chloe Pace, Charles Taylor, Yoichi Kaneuchi, Scott Evans, Adesegun Abudu

    Journal of Bone Oncology　28　2021年6月1日

    出版者・発行元： Elsevier GmbH

    DOI： 10.1016/j.jbo.2021.100359 　

    ISSN：2212-1374

  21. スポーツ少年団における暴言・体罰を許容する保護者の特徴

    矢部 裕, 萩原 嘉廣, 関口 拓矢, 吉田 新一郎, 井樋 栄二

    日本整形外科学会雑誌　95　(3)　S853-S853　2021年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

  22. Characteristics of Parents Who Feel a Lack of Communication with Coaches of Youth Sports.

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Shinichirou Yoshida, Eiji Itoi, Ryoichi Nagatomi

    The Tohoku journal of experimental medicine　253　(3)　191-198　2021年3月

    DOI： 10.1620/tjem.253.191 　

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    Communication between parents and their children's coaches is important for children's sports activities, but the relationship between parents and coaches is not well understood. It is possible that parents feel a lack of communication with coaches, which could be due to parents' experience with sports activities or the social environment of the team. This study aimed to elucidate the characteristics of parents who feel a lack of communication with their children's coaches of youth sports. A cross-sectional study was conducted on parents of young athletes (n = 6,641) and multivariate logistic regression analyses were performed to assess factors related to parents' feeling of a lack of communication with their children's coaches. Among the respondents, 29.4% of parents felt a lack of communication with their children's coaches. The factors related to the parents' feeling were a shorter duration of their children playing the present sport, an absence of experience playing the same sport as their children or playing in a team with high competition level, dissatisfaction with their children's attitude towards sports activities, and an awareness of verbal and/or physical abuse by the coaches and bullying by the teammates in their children's team. Parents' previous sports experience and awareness of interpersonal violence in their children's team were associated with their feeling of a lack of communication with coaches. Educating parents on the sport and their roles in youth sport is necessary to make appropriate mutual communication between parents and coaches, which could lead to better circumstances for young athletes.

  23. Association of musculoskeletal pain in other body parts with new-onset shoulder pain: a longitudinal study among survivors of the Great East Japan Earthquake. 国際誌

    Yoshihiro Hagiwara, Yutaka Yabe, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Takahiro Onoki, Tadahisa Takahashi, Jun Iwatsu, Ichiro Tsuji, Eiji Itoi

    BMJ open　11　(2)　e041804　2021年2月15日

    DOI： 10.1136/bmjopen-2020-041804 　

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    OBJECTIVE: Shoulder pain is a common health problem coexisting with other musculoskeletal pain. However, the effects of pre-existing musculoskeletal pain on the development of shoulder pain are not clear. The present study aimed to elucidate the association between coexisting musculoskeletal pain at other body sites and new-onset shoulder pain among survivors of the Great East Japan Earthquake (GEJE). DESIGN: This is a longitudinal study. SETTING: The study was conducted at the severely damaged coastal areas in Ishinomaki and Sendai cities. PARTICIPANTS: The survivors who did not have shoulder pain at 3 years after the GEJE were followed up 1 year later (n=2131). INTERVENTIONS: Musculoskeletal pain (low back, hand and/or foot, knee, shoulder and neck pain) was assessed using self-reported questionnaires. MAIN OUTCOME MEASURES: The outcome of interest was new-onset shoulder pain, which was defined as shoulder pain absent at 3 years but present at 4 years after the disaster. The main predictive factor for new-onset shoulder pain was musculoskeletal pain in other body parts at 3 years after the GEJE; this was categorised according to the number of pain sites (0, 1, ≥2). Multiple regression analyses were conducted to calculate the odds ratio (OR) and 95% confidence interval (CI) for new-onset shoulder pain due to musculoskeletal pain in other body parts. RESULTS: The incidence of new-onset shoulder pain was 6.7% (143/2131). Musculoskeletal pain in other body parts was significantly associated with new-onset shoulder pain. Using the survivors without other musculoskeletal pain as reference, the adjusted OR and 95% CI for new-onset shoulder pain were 1.86 (1.18 to 2.94) for those with one body part and 3.22 (2.08 to 4.98) for those with ≥2 body parts presenting with musculoskeletal pain (p<0.001). CONCLUSIONS: Pre-existing musculoskeletal pain in other body parts was significantly associated with new-onset shoulder pain among survivors; this provides useful information for clinical and public health policies.

  24. A 5-year Longitudinal Study of Low Back Pain in Survivors of the Great East Japan Earthquake. 国際誌

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Yasuhito Sogi, Takahiro Onoki, Kazuaki Suzuki, Tadahisa Takahashi, Jun Iwatsu, Ichiro Tsuji, Eiji Itoi

    Spine　46　(10)　695-701　2020年12月8日

    DOI： 10.1097/BRS.0000000000003860 　

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    STUDY DESIGN: A longitudinal panel study. OBJECTIVE: The aim of this study was to examine the occurrence of low back pain (LBP), especially the association of previous LBP with further episodes of LBP, in survivors of the Great East Japan Earthquake (GEJE) during the course of 5 years. SUMMARY OF BACKGROUND DATA: LBP is common among survivors of natural disasters, but its long-term course is not clear. METHODS: A 5-year longitudinal study was conducted among survivors of the GEJE (n = 1821). The presence of LBP was assessed using a self-reported questionnaire at 2, 4, and 7 years after the disaster (termed the first, second, and third time points, respectively). Multiple logistic regression analysis was performed to assess a potential association between LBP at the first and second time points with LBP at the third time point, and the odds ratios (ORs) and 95% confidence intervals (CI) were calculated. RESULTS: The prevalence of LBP was 25.3%, 27.3%, and 27.2% at the first, second, and third time points, respectively. The occurrence of LBP at the first time point was significantly associated with LBP at the third time point, and the adjusted odds ratio (OR) (95% confidence interval [CI]) was 5.47 (4.28-6.98). Furthermore, LBP at the first and second time points was significantly associated with LBP at the third time point. Compared to no LBP at the first and second time points, the adjusted OR (95% CIs) for LBP at the third time point was 4.12 (3.14-5.41) in the case of LBP at either of the first or second time points and 10.73 (7.80-14.76) for LBP at both time points (P for trend < 0.001). CONCLUSION: Previous LBP was associated with LBP 5 years later among survivors of the GEJE. Furthermore, the effect on subsequent LBP was stronger with a higher frequency of previous LBP episodes. LEVEL OF EVIDENCE: 3.

  25. Joint hemorrhage accelerates cartilage degeneration in a rat immobilized knee model. 国際誌

    Yasuhito Sogi, Yutaka Yabe, Yoshihiro Hagiwara, Masahiro Tsuchiya, Yoshito Onoda, Takuya Sekiguchi, Nobuyuki Itaya, Shinichiro Yoshida, Toshihisa Yano, Kazuaki Suzuki, Takahiro Onoki, Eiji Itoi

    BMC musculoskeletal disorders　21　(1)　761-761　2020年11月19日

    DOI： 10.1186/s12891-020-03795-0 　

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    BACKGROUND: Joint hemorrhage is caused by trauma, ligament reconstruction surgery, and bleeding disorders such as hemophilia. Recurrence of hemorrhage in the joint space induces hemosiderotic synovitis and oxidative stress, resulting in both articular cartilage degeneration and arthropathy. Joint immobilization is a common treatment option for articular fractures accompanied by joint hemorrhage. Although joint hemorrhage has negative effects on the articular cartilage, there is no consensus on whether a reduction in joint hemorrhage would effectively prevent articular cartilage degeneration. The purpose of this study was to investigate the effect of joint hemorrhage combined with joint immobilization on articular cartilage degeneration in a rat immobilized knee model. METHODS: The knee joints of adult male rats were immobilized at the flexion using an internal fixator from 3 days to 8 weeks. The rats were randomly divided into the following groups: immobilized blood injection (Im-B) and immobilized-normal saline injection (Im-NS) groups. The cartilage was evaluated in two areas (contact and non-contact areas). The cartilage was used to assess chondrocyte count, Modified Mankin score, and cartilage thickness. The total RNA was extracted from the cartilage in both areas, and the expression of metalloproteinase (MMP)-8, MMP-13, interleukin (IL)-1β, and tumor necrosis factor (TNF)-α was measured by quantitative real-time polymerase chain reaction. RESULTS: The number of chondrocytes in the Im-B group significantly decreased in both areas, compared with that in the Im-NS group. Modified Mankin score from 4 to 8 weeks of the Im-B group was significantly higher than that of the Im-NS group only in the contact area. The expression of MMP-8 and MMP-13 from 2 to 4 weeks and TNF-α from 2 to 8 weeks significantly increased in the Im-B group compared with those in the Im-NS group, but there was no significant difference in IL-1β expression. CONCLUSIONS: The results showed that joint hemorrhage exacerbated immobilization-induced articular cartilage degeneration. Drainage of a joint hemorrhage or avoidance of loading may help prevent cartilage degeneration during joint immobilization with a hemorrhage.

  26. Low Back Pain in School-Aged Martial Arts Athletes in Japan: A Comparison among Judo, Kendo, and Karate. 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Eiji Itoi, Ryoichi Nagatomi

    The Tohoku journal of experimental medicine　251　(4)　295-301　2020年8月

    DOI： 10.1620/tjem.251.295 　

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    Martial arts, such as judo, kendo, and karate, are popular worldwide, not only among adults but also among children and adolescents. Although low back pain (LBP) is considered to be a common problem in these sports, it has been scarcely studied, especially in young athletes. The purpose of this study was to elucidate the point prevalence of and factors related to LBP among school-aged athletes in judo, kendo, and karate. A cross-sectional study was conducted in school-aged athletes (age, 6-15 years; n = 896) using a self-reported questionnaire. Multiple logistic regression models were used to assess the factors related to LBP along with the odds ratio (OR) and 95% confidence interval (95% CI). Variables included in the analysis were sex, age, body mass index, team level, number of days and hours of training, frequency of participation in games, practice intensity, and lower extremity pain. The prevalence of LBP was 6.9% in judo, 4.7% in kendo, and 2.9% in karate. Older age was significantly associated with LBP in judo (adjusted OR, 2.12 [95% CI, 1.24-3.61]), kendo (1.77 [1.27-2.47]), and karate (2.22 [1.14-4.33]). Lower extremity pain was significantly associated with LBP in judo (6.56 [1.57-27.34]) and kendo (21.66 [6.96-67.41]). Coaches should understand the characteristics of LBP in each martial art to develop strategies to prevent LBP among school-aged martial arts athletes.

  27. 軟部肉腫に対する術前放射線治療の効果と予後への影響

    吉田 新一郎, Adesegun Abudu, 金内 洋一, 綿貫 宗則, 保坂 正美, 井樋 栄二

    日本整形外科学会雑誌　94　(6)　S1446-S1446　2020年7月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

    eISSN：2758-7479

  28. 小児骨肉腫における診断遅延の影響

    吉田 新一郎, Adesegun Abudu, 金内 洋一, 綿貫 宗則, 保坂 正美, 井樋 栄二

    日本整形外科学会雑誌　94　(6)　S1452-S1452　2020年7月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

    eISSN：2758-7479

  29. Preceding Poor Physical Function Is Associated with New-Onset Musculoskeletal Pain among Older Natural Disaster Survivors: A Longitudinal Study after the Great East Japan Earthquake. 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Tadahisa Takahashi, Jun Iwatsu, Ichiro Tsuji, Eiji Itoi

    The Tohoku journal of experimental medicine　251　(1)　19-26　2020年5月

    DOI： 10.1620/tjem.251.19 　

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    Musculoskeletal pain is a major problem among survivors of natural disasters. Functional disabilities in older adults increase after disasters and can lead to musculoskeletal pain. However, the effects of poor physical function on musculoskeletal pain after natural disasters remain unclear. This study aimed to elucidate the association of poor physical function with new-onset musculoskeletal pain among older survivors after the Great East Japan Earthquake (GEJE). Survivors aged ≥ 65 years, 3 years after the GEJE, were assessed longitudinally for 1 year (n = 646). Musculoskeletal pain was assessed using a self-reported questionnaire, and new-onset musculoskeletal pain was defined as absence and presence of pain at 3 years and 4 years, respectively, after the disaster. Physical function at 3 years after the disaster was assessed using the Kihon Checklist physical function score, which consists of 5 yes/no questions, and poor physical function was defined as a score of ≥ 3/5. Multivariate logistic regression analyses were used to assess the association of poor physical function with new-onset musculoskeletal pain. The incidence of new-onset musculoskeletal pain was 22.4%. Participants with poor physical function had a significantly higher rate of new-onset musculoskeletal pain. Compared with high physical function, the adjusted odds ratio (95% confidence interval) for new-onset musculoskeletal pain was 2.25 (1.37-3.69) in poor physical function (P = 0.001). Preceding poor physical function was associated with new-onset musculoskeletal pain among older survivors after the GEJE. There is need to focus on the maintenance of physical function to prevent musculoskeletal pain after natural disasters.

  30. Association between lower back pain and lower extremity pain among young volleyball players: A cross-sectional study. 国際誌 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Eiji Itoi, Ryoichi Nagatomi

    Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine　43　65-69　2020年5月

    DOI： 10.1016/j.ptsp.2020.02.005 　

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    BACKGROUND: Lower back pain (LBP), as well as lower extremity injuries, are major problems among young volleyball players. Nevertheless, only few studies have focused on the relationship between lower extremity injuries and LBP. OBJECTIVE: This study investigated the association between LBP and lower extremity pain, including knee and ankle pain, among young volleyball players. DESIGN: Cross-sectional study. SETTING: Amateur sports association. PARTICIPANTS: Elementary and middle school-aged athletes (6-15 years of age). MAIN OUTCOME MEASURES: LBP and lower extremity pain. RESULTS: A total of 566 young volleyball players participated in this study. The point prevalence of LBP among young volleyball players was 9.5%. Using absence of lower extremity pain as a reference, the adjusted odds ratio (95% confidence interval) for LBP was 11.07 (5.64-21.71) in the presence of lower extremity pain. CONCLUSIONS: LBP is associated with Lower extremity pain among young volleyball players. Careful attention should be paid to lower extremity complaints to prevent and treat LBP among young volleyball players.

  31. Musculoskeletal pain in other body sites is associated with new-onset low back pain: a longitudinal study among survivors of the great East Japan earthquake. 国際誌 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Tadahisa Takahashi, Jun Iwatsu, Ichiro Tsuji, Eiji Itoi

    BMC musculoskeletal disorders　21　(1)　227-227　2020年4月13日

    DOI： 10.1186/s12891-020-03234-0 　

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    BACKGROUND: Low back pain (LBP) is a common health problem experienced after natural disasters. LBP is often concurrent with other musculoskeletal pain; however, the effects of preexisting musculoskeletal pain on the development of LBP are not clear. The purpose of this study was to elucidate the association of musculoskeletal pain in other body sites with new-onset LBP among survivors of the Great East Japan Earthquake (GEJE). METHODS: A longitudinal study was conducted with survivors of the GEJE. The survivors who did not have LBP at the 3 year time period after the GEJE were followed up 1 year later (n = 1782). Musculoskeletal pain, such as low back, hand and/or foot, knee, shoulder, and neck pain, were assessed with self-reported questionnaires. The outcome of interest was new-onset LBP, which was defined as LBP absent at 3 years but present at 4 years after the disaster. The main predictor was musculoskeletal pain in other body sites 3 years after the GEJE, which was categorized according to the number of pain sites (0, 1, ≥ 2). Multiple regression analyses were performed to calculate the odds ratio (OR) and 95% confidence interval (CI) for new-onset LBP due to musculoskeletal pain in other body sites. RESULTS: The incidence of new-onset LBP was 14.1% (251/1782). Musculoskeletal pain in other body sites was significantly associated with new-onset LBP. Including people without other musculoskeletal pain as a reference, the adjusted OR and 95% CI for new-onset LBP were 1.73 (1.16-2.57) for people with one musculoskeletal pain site and 3.20 (2.01-5.09) for people with ≥ 2 sites (p <  0.001). CONCLUSIONS: Preexisting musculoskeletal pain in other body sites was associated with new-onset LBP among survivors in the recovery period after the GEJE.

  32. Upper Extremity Pain Is Associated with Lower Back Pain among Young Basketball Players: A Cross-Sectional Study. 査読有り

    Yoshihiro Hagiwara, Yutaka Yabe, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Eiji Itoi, Ryoichi Nagatomi

    The Tohoku journal of experimental medicine　250　(2)　79-85　2020年2月

    DOI： 10.1620/tjem.250.79 　

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    Basketball is a major sport worldwide among different age groups that leads to a high frequency of injuries at multiple body sites. Upper and lower extremities and lower back are common pain sites in basketball players; however, there is little information about the relationship between upper or lower extremity pain and lower back pain. This study elucidated the associations between upper extremity (shoulder and elbow) pain and lower back pain (LBP) among young basketball players. We conducted a cross-sectional study using self-reported questionnaires mailed to 25,669 young athletes; the final study population comprised 590 basketball players, and their median age was 13 years (range: 6-15 years). The point prevalence rates of lower back, shoulder, elbow, and upper extremity pain among young basketball players were 12.9% (76/590), 4.6% (27/590), 2.7% (16/590), and 7.1% (42/590), respectively. Multivariate logistic regression analyses revealed that upper extremity pain was significantly associated with LBP (adjusted odds ratio [OR]: 7.86; 95% confidential interval [CI], 3.93-15.72). Shoulder pain was significantly associated with training per week (> 4 days) (adjusted OR: 4.15; 95% CI: 1.29-13.40) and LBP (adjusted OR: 13.77; 95% CI: 5.70-33.24). This study indicates that upper extremity and shoulder pain is associated with LBP among young basketball players. Assessing for lower back pain, as well as elbow and/or shoulder pain, may help prevent severe injuries in young basketball players. In conclusion, parents and coaches should be properly re-educated to help improve lower back, upper extremity, and shoulder pain among young basketball players.

  33. Bladder perforation by orthopedic implants 26 years after limb-sparing surgery for left proximal femoral chondrosarcoma: A case report. 国際誌

    Jun Iwatsu, Munenori Watanuki, Kouu Hayashi, Shinichirou Yoshida, Toshihisa Yano, Masahito Hatori, Masami Hosaka, Yoshihiro Hagiwara, Eiji Itoi

    International journal of surgery case reports　76　441-445　2020年

    DOI： 10.1016/j.ijscr.2020.09.175 　

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    INTRODUCTION: The need for implant use during orthopedic surgeries has been increasing. Accordingly, increased implant failures have been reported. However, bladder perforation remains a rare complication after orthopedic surgery. Although a few reports have described bladder perforation after total hip arthroplasty, no previous studies have reported the migration of staples into the bladder after limb-sparing surgery. PRESENTATION OF CASE: A 65-year-old patient underwent limb-sparing surgery to remove a chondrosarcoma in the left proximal thigh. Twenty-six years after surgery, a staple that had been used to fix artificial ligaments to the pubis migrated to perforate the bladder, resulting in painful urination. The staple was removed, and her symptoms improved. DISCUSSION: In this case, bladder perforation by the staple resulted in painful urination. The bladder perforation was not detected until 26 years after the initial surgery. CONCLUSION: Our observations emphasize that implant complications may occur even after a long postoperative period, and the possibility of delayed bladder perforation from previous pelvic surgeries should be considered in patients presenting with urinary tract symptoms.

  34. High prevalence of low back pain among young basketball players with lower extremity pain: a cross-sectional study. 国際誌 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Eiji Itoi, Ryoichi Nagatomi

    BMC sports science, medicine & rehabilitation　12　40-40　2020年

    DOI： 10.1186/s13102-020-00189-6 　

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    Background: Low back pain (LBP) is a common problem among young basketball players in addition to lower extremity injuries. However, studies that focus on LBP with lower extremity pain are limited. From the perspective of the kinematic chain, disrupted lower extremity function can lead to LBP. The association between these two symptoms in basketball players, however, has not been reported. Therefore, this study aimed to clarify the association between lower extremity pain and LBP among young basketball players. Methods: This cross-sectional study was conducted on school-aged basketball players (n = 592). Information regarding their sporting activities was collected using a self-reported questionnaire. Musculoskeletal pain such as low back, knee, and ankle pain was assessed. The sports players with knee and/or ankle pain were defined as having lower extremity pain. Multivariate logistic regression analysis was used to assess the association between lower extremity pain and LBP. Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated. The associations of knee or ankle pain with LBP were similarly assessed. Results: School-aged basketball players had a point prevalence of 12.8% for LBP. Compared with the players without lower extremity pain, the players with lower extremity pain had higher rates of LBP, with an adjusted OR (95% CI) of 6.21 (3.57-10.80). There was also a significant association of knee and ankle pain with LBP. Compared with the players without knee or ankle pain, the adjusted ORs (95% CI) for LBP were 4.25 (2.55-7.07) in the players with knee pain and 3.79 (2.26-6.36) in the players with ankle pain. Conclusions: Lower extremity pain was associated with LBP among school-aged basketball players. Further research is needed to clarify the mechanism of this association, which will provide useful information for prevention and treatment of LBP among young basketball players.

  35. Restriction in the hip internal rotation of the stride leg is associated with elbow and shoulder pain in elite young baseball players. 国際誌 査読有り

    Takuya Sekiguchi, Yoshihiro Hagiwara, Yutaka Yabe, Masahiro Tsuchiya, Nobuyuki Itaya, Shinichiro Yoshida, Toshihisa Yano, Yasuhito Sogi, Kazuaki Suzuki, Eiji Itoi

    Journal of shoulder and elbow surgery　29　(1)　139-145　2020年1月

    DOI： 10.1016/j.jse.2019.07.004 　

    ISSN：1058-2746

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    BACKGROUND: Evidence is scarce concerning the relationship of physical dysfunction of the trunk and lower extremities with elbow and shoulder pain in young baseball players. This study aimed to examine the association of joint flexibility of the trunk and lower extremities and dynamic postural control with elbow and shoulder pain among elite young baseball players. METHODS: We analyzed baseball players (aged 9-12 years) who participated in the National Junior Sports Clubs Baseball Festival. Range of motion in external rotation and internal rotation (IR) of the hip, as well as the finger-to-floor distance and heel-to-buttock distance, was measured. The straight-leg-raise test was also conducted. Dynamic postural control was evaluated using the Star Excursion Balance Test. Multivariable logistic regression analyses were conducted to examine the association of physical function with the elbow or shoulder pain incidence. RESULTS: Of 210 players surveyed, 177 without elbow or shoulder pain were included in the analysis. Of the participants, 16 (9.0%) reported having elbow or shoulder pain during the tournament. Participants with the incidence of elbow or shoulder pain had a significant restriction in hip IR of the stride leg compared with those without pain (35.8° vs. 43.7°, P = .022). There were no significant associations of other joint flexibilities and the Star Excursion Balance Test with elbow or shoulder pain. CONCLUSION: Decreased hip IR range of motion of the stride leg was significantly associated with the elbow or shoulder pain incidence. Players, coaches, and clinicians should consider the physical function of the trunk and lower extremities for the prevention of elbow and shoulder pain.

  36. Parents' Own Experience of Verbal Abuse Is Associated with their Acceptance of Abuse towards Children from Youth Sports Coaches. 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Masashi Koide, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Eiji Itoi, Ryoichi Nagatomi

    The Tohoku journal of experimental medicine　249　(4)　249-254　2019年12月

    DOI： 10.1620/tjem.249.249 　

    ISSN：0040-8727

    eISSN：1349-3329

  37. Musculoskeletal pain and new-onset poor physical function in elderly survivors of a natural disaster: a longitudinal study after the great East Japan earthquake. 国際誌 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Takahiro Onoki, Ichiro Tsuji, Eiji Itoi

    BMC geriatrics　19　(1)　274-274　2019年10月17日

    DOI： 10.1186/s12877-019-1283-z 　

    eISSN：1471-2318

  38. Association between continued residence in temporary prefabricated housing and musculoskeletal pain in survivors of the Great East Japan Earthquake: a longitudinal study. 国際誌 査読有り

    Yasuhito Sogi, Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Masashi Koide, Nobuyuki Itaya, Shinichirou Yoshida, Toshihisa Yano, Ichiro Tsuji, Eiji Itoi

    BMJ open　9　(10)　e030761　2019年10月3日

    DOI： 10.1136/bmjopen-2019-030761 　

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    OBJECTIVE: Prolonged periods of living in prefabricated houses (PHs) may increase the risk of musculoskeletal (MSK) symptoms; however, the association is not clear. This study aimed to investigate the association between continued residence in PHs and MSK pain in a population affected by a natural disaster, the Great East Japan Earthquake (GEJE) survivors. DESIGN, SETTING AND PARTICIPANTS: A panel study was conducted including 1059 and 792 survivors at 2 and 4 years, respectively, after the GEJE, using a self-reported questionnaire. Those with no response on living status and those who did not live in a PH were excluded. Participants were classified into two groups by living status: continued residence in a PH (lived in a PH during both periods) or moving out of a PH (lived in a PH in the first period and did not live in a PH in the second). PRIMARY OUTCOME MEASURE: MSK pain included lower back, shoulder, knee, hand or foot, and neck pain. Changes in the occurrence of MSK pain during the two periods were assessed and defined as 'new-onset' and 'continuing' MSK pain. Multiple logistic regression analysis was used to examine the influence of continued residence in a PH on new-onset and continuing MSK pain. RESULTS: Continued residence in a PH was significantly associated with new-onset MSK pain, even after adjustment for covariates (adjusted OR 2.18, 95% CI 1.25 to 3.79, p=0.006). Participants who continued living in a PH had higher rates of continuing MSK pain than those who moved out; however, the difference was not significant (adjusted OR 1.69, 95% CI 0.94 to 3.05, p=0.079). CONCLUSION: Continued residence in a PH was associated with new-onset MSK pain among survivors. Public support should be provided to such people to ensure a more comfortable life.

  39. 凍結肩の関節包における、RAGEによるNF-κB反応経路の活性化

    矢野 利尚, 萩原 嘉廣, 矢部 裕, 関口 拓矢, 小出 将志, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 鈴木 一瑛, 井樋 栄二

    日本整形外科学会雑誌　93　(8)　S1763-S1763　2019年9月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

  40. ラット膝関節不動化モデルにおける関節血腫は軟骨変性への影響

    曽木 靖仁, 萩原 嘉廣, 矢部 裕, 小野田 祥人, 関口 拓矢, 板谷 信行, 吉田 新一郎, 矢野 利尚, 鈴木 一瑛, 井樋 栄二

    日本整形外科学会雑誌　93　(8)　S1933-S1933　2019年9月

    出版者・発行元： (公社)日本整形外科学会

    ISSN：0021-5325

  41. Extracellular α-synuclein enters dopaminergic cells by modulating flotillin-1-assisted dopamine transporter endocytosis. 国際誌 査読有り

    Kobayashi J, Hasegawa T, Sugeno N, Yoshida S, Akiyama T, Fujimori K, Hatakeyama H, Miki Y, Tomiyama A, Kawata Y, Fukuda M, Kawahata I, Yamakuni T, Ezura M, Kikuchi A, Baba T, Takeda A, Kanzaki M, Wakabayashi K, Okano H, Aoki M

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology　33　(9)　10240-10256　2019年9月

    DOI： 10.1096/fj.201802051R 　

    ISSN：0892-6638

  42. Involvement of inflammasome activation via elevation of uric acid level in nociception in a mouse model of muscle pain. 査読有り

    Yoshida S, Hagiwara Y, Tsuchiya M, Shinoda M, Koide M, Hatakeyama H, Chaweewannakorn C, Suzuki K, Yano T, Sogi Y, Itaya N, Sekiguchi T, Yabe Y, Sasaki K, Kanzaki M, Itoi E

    Molecular pain　15　1744806919858797　2019年7月

    DOI： 10.1177/1744806919858797 　

    ISSN：1744-8069

    eISSN：1744-8069

  43. Verbal Abuse from Coaches Is Associated with Loss of Motivation for the Present Sport in Young Athletes: A Cross-Sectional Study in Miyagi Prefecture. 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kaoru Kuroki, Kenji Kanazawa, Masashi Koide, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Eiji Itoi, Ryoichi Nagatomi

    The Tohoku journal of experimental medicine　248　(2)　107-113　2019年6月

    DOI： 10.1620/tjem.248.107 　

    ISSN：0040-8727

    eISSN：1349-3329

  44. Musculoskeletal Pain is Associated With New-Onset Psychological Distress in Survivors of the Great East Japan Earthquake. 国際誌 査読有り

    Yabe Y, Hagiwara Y, Sekiguchi T, Sugawara Y, Tsuchiya M, Koide M, Itaya N, Yoshida S, Sogi Y, Yano T, Tsuji I, Itoi E

    Disaster medicine and public health preparedness　13　(2)　295-300　2019年4月

    DOI： 10.1017/dmp.2018.57 　

    ISSN：1935-7893

  45. The characteristics of coaches that verbally and physically abuse young baseball players using a self-reported questionnaire. 査読有り

    Yoshihiro Hagiwara, Takuya Sekiguchi, Yutaka Yabe, Haruki Momma, Masahiro Tsuchiya, Kenji Kanazawa, Masashi Koide, Nobuyuki Itaya, Shinichiro Yoshida, Yasuhito Sogi, Toshihisa Yano, Eiji Itoi, Ryoichi Nagatomi

    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association　24　(2)　361-367　2019年3月

    DOI： 10.1016/j.jos.2018.06.024 　

    ISSN：0949-2658

    詳細を見る 詳細を閉じる

    BACKGROUND: Because the relationship between coaches and athletes is unequal, verbal and physical abuse remains a common problem among sports coaches. We aimed to elucidate the characteristics of baseball coaches who verbally/physically abuse young baseball players. METHODS: A cross-sectional study was conducted on youth sports team coaches in Miyagi prefecture, Japan (n = 380), using a self-reported questionnaire. Multivariate logistic regression models were used for the analyses, evaluating the following variables: sex, age, educational level, smoking habits, years of coaching, level of baseball-playing experience, personal experience with verbal/physical abuse by former coaches, satisfaction with athletes' attitudes, number of athletes on the team, team competition level, awareness of the recommendations of the Japanese Society of Clinical Sports Medicine, limitations in the total pitch count, difficulty in coaching in other positions, number of games per year, and acceptance of former verbal/physical abuse. RESULTS: The prevalence of verbal/physical abuse toward young athletes was 74.5% (n = 283) and 6.6% (n = 25), respectively. Verbal abuse was significantly associated with personal experience of verbal abuse by former coaches (odds ratio [OR]: 2.00, 95% confidence interval [95% CI]: 1.04-3.85), and acceptance of verbal/physical abuse (OR: 2.61, 95% CI: 1.34-5.10). Physical abuse was significantly associated with greater than 10 years of coaching experience (OR: 7.16, 95% CI: 1.36-37.78), personal experience with physical abuse by former coaches (OR: 4.25, 95% CI: 1.23-14.70), and acceptance of verbal/physical abuse (OR: 3.85, 95% CI: 1.51-9.84). CONCLUSIONS: Coaches' experiences with verbal/physical abuse by former coaches negatively affected young athletes. Breaking this cycle is necessary to keep athletes active and interested in playing baseball. LEVEL OF EVIDENCE: Level III.

  46. Knee pain is associated with lower back pain in young baseball players: a cross-sectional study. 国際誌 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Haruki Momma, Masahiro Tsuchiya, Kaoru Kuroki, Kenji Kanazawa, Masashi Koide, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Eiji Itoi, Ryoichi Nagatomi

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA　27　(3)　985-990　2019年3月

    DOI： 10.1007/s00167-018-5129-6 　

    ISSN：0942-2056

    eISSN：1433-7347

  47. Arthroscopic Excision of Intra-Articular Osteoid Osteoma at the Elbow. 国際誌 査読有り

    Taku Hatta, Masami Hosaka, Munenori Watanuki, Toshihisa Yano, Shinichirou Yoshida, Mika Watanabe, Shin Hitachi, Eiji Itoi

    Case reports in orthopedics　2019　8505382-8505382　2019年

    DOI： 10.1155/2019/8505382 　

    ISSN：2090-6749

    詳細を見る 詳細を閉じる

    Osteoid osteoma (OO) apparent in the intra-articular region of the elbow is very rare. Although computed tomography-guided excision and radiofrequency ablation have been recognized as useful treatment options, arthroscopic excision has recently received focus as an alternative strategy for lesions close to neurovascular structures or intra- and juxta-articular lesions. We herein report a 17-year-old female who underwent arthroscopic treatment for intra-articular OO located at the olecranon/coronoid fossa. Her symptoms included elbow pain that was exacerbated at night and contracture of elbow flexion-extension, and she was diagnosed with intra-articular OO after 12 months of symptomatic history. Arthroscopically, thorough synovectomy for both the anterior and posterior aspects of the joint enabled definition of the tumor margin with hyperemic alteration and excision of the lesion as an en bloc specimen. At the 12-month follow-up, the patient had no recurrence of elbow limitation or pain. This case report describes the advantages of arthroscopic treatment, including a low-invasive approach and easy accessibility to the whole intra-articular space, which can provide clear visualization of the tumorous lesion.

  48. Playing video games for more than 3 hours a day is associated with shoulder and elbow pain in elite young male baseball players. 国際誌 査読有り

    Sekiguchi T, Hagiwara Y, Yabe Y, Tsuchiya M, Itaya N, Yoshida S, Yano T, Sogi Y, Suzuki K, Itoi E

    Journal of shoulder and elbow surgery　27　(9)　1629-1635　2018年9月

    DOI： 10.1016/j.jse.2018.06.005 　

    ISSN：1058-2746

  49. Sleep Disturbance Is Associated with New Onset and Continuation of Lower Back Pain: A Longitudinal Study among Survivors of the Great East Japan Earthquake. 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Masashi Koide, Nobuyuki Itaya, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Ichiro Tsuji, Eiji Itoi

    The Tohoku journal of experimental medicine　246　(1)　9-14　2018年9月

    DOI： 10.1620/tjem.246.9 　

    ISSN：0040-8727

    eISSN：1349-3329

  50. Excessive game playing is associated with musculoskeletal pain among youth athletes: a cross-sectional study in Miyagi prefecture. 国際誌 査読有り

    Sekiguchi T, Hagiwara Y, Momma H, Tsuchiya M, Kuroki K, Kanazawa K, Yabe Y, Yoshida S, Koide M, Itaya N, Itoi E, Nagatomi R

    Journal of sports sciences　36　(16)　1801-1807　2018年8月

    DOI： 10.1080/02640414.2017.1420453 　

    ISSN：0264-0414

  51. Roles of IL-1α/β in regeneration of cardiotoxin-injured muscle and satellite cell function. 国際誌 査読有り

    Chaweewannakorn C, Tsuchiya M, Koide M, Hatakeyama H, Tanaka Y, Yoshida S, Sugawara S, Hagiwara Y, Sasaki K, Kanzaki M

    American journal of physiology. Regulatory, integrative and comparative physiology　315　(1)　R90-R103-R103　2018年7月1日

    DOI： 10.1152/ajpregu.00310.2017 　

    ISSN：0363-6119

    eISSN：1522-1490

  52. Effects of Low-Intensity Pulsed Ultrasound for Preventing Joint Stiffness in Immobilized Knee Model in Rats. 国際誌 査読有り

    Nobuyuki Itaya, Yutake Yabe, Yoshihiro Hagiwara, Kenji Kanazawa, Masashi Koide, Takuya Sekiguchi, Shinichirou Yoshida, Yasuhito Sogi, Toshihisa Yano, Masahiro Tsuchiya, Yoshihumi Saijo, Eiji Itoi

    Ultrasound in medicine & biology　44　(6)　1244-1256　2018年6月

    DOI： 10.1016/j.ultrasmedbio.2018.02.002 　

    ISSN：0301-5629

    eISSN：1879-291X

  53. The Characteristics of Coaches that Verbally or Physically Abuse Young Athletes. 査読有り

    Yabe Y, Hagiwara Y, Sekiguchi T, Momma H, Tsuchiya M, Kuroki K, Kanazawa K, Koide M, Itaya N, Yoshida S, Sogi Y, Yano T, Itoi E, Nagatomi R

    The Tohoku journal of experimental medicine　244　(4)　297-304　2018年4月

    DOI： 10.1620/tjem.244.297 　

    ISSN：0040-8727

  54. Association between sleep disturbance and new-onset subjective knee pain in Great East Japan Earthquake survivors: A prospective cohort study in the Miyagi prefecture 査読有り

    Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Yutaka Yabe, Masashi Koide, Nobuyuki Itaya, Shinichiro Yoshida, Yasuhito Sogi, Masahiro Tsuchiya, Ichiro Tsuji, Eiji Itoi

    Journal of Orthopaedic Science　23　(2)　334-340　2018年3月1日

    DOI： 10.1016/j.jos.2017.10.011 　

    ISSN：1436-2023 0949-2658

  55. Involvement of neutrophils and interleukin-18 in nociception in a mouse model of muscle pain. 査読有り

    Yoshida S, Hagiwara Y, Tsuchiya M, Shinoda M, Koide M, Hatakeyama H, Chaweewannakorn C, Yano T, Sogi Y, Itaya N, Sekiguchi T, Yabe Y, Sasaki K, Kanzaki M, Itoi E

    Molecular pain　14　1744806918757286　2018年2月

    DOI： 10.1177/1744806918757286 　

    ISSN：1744-8069

  56. Higher Incidence of Sleep Disturbance among Survivors with Musculoskeletal Pain after the Great East Japan Earthquake: A Prospective Study. 査読有り

    Yutaka Yabe, Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Masahiro Tsuchiya, Masashi Koide, Nobuyuki Itaya, Shinichiro Yoshida, Yasuhito Sogi, Toshihisa Yano, Ichiro Tsuji, Eiji Itoi

    The Tohoku journal of experimental medicine　244　(1)　25-32　2018年1月

    DOI： 10.1620/tjem.244.25 　

    ISSN：0040-8727

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    Sleep disturbance is a common symptom after natural disasters. Although musculoskeletal pain also increases after natural disasters, its relation to sleep disturbance is not clear. The purpose of this study was to determine the influence of musculoskeletal pain on new-onset sleep disturbance among survivors after the Great East Japan Earthquake (GEJE). A prospective cohort study was conducted with the survivors of the GEJE at two and three years after the earthquake. New-onset sleep disturbance was defined as sleep disturbance absent at two years and present at three years after the earthquake. The sites of musculoskeletal pain included low back, shoulder, knee, and hand or foot. The number of musculoskeletal pain sites at two years after the earthquake was divided into three categories (0, 1, and 2 or more). Univariate and multivariate logistic regression models were used to calculate the odds ratio (OR) and 95% confidence interval (95%CI) for new-onset sleep disturbance according to the number of musculoskeletal pain sites. A total of 1,102 survivors were included in this study and 14.6% of the participants reported new-onset sleep disturbance. Using "0" as a reference, the adjusted ORs (95% CI) for new-onset sleep disturbance were 2.43 (1.55-3.80) in "1" and 2.96 (1.88-4.64) in "2 or more", respectively (P for trends < 0.001). In conclusion, this is the first study showing higher incidence of sleep disturbance among survivors with musculoskeletal pain after the GEJE. Care for musculoskeletal pain is important to prevent sleep disturbance after natural disasters.

  57. Effects of Arthroscopic Coracohumeral Ligament Release on Range of Motion for Patients with Frozen Shoulder. 国際誌 査読有り

    Hagiwara Y, Sekiguchi T, Ando A, Kanazawa K, Koide M, Hamada J, Yabe Y, Yoshida S, Itoi E

    The open orthopaedics journal　12　373-379　2018年

    DOI： 10.2174/1874325001812010373 　

  58. Association between trunk pain and lower extremity pain among youth soccer players: a cross-sectional study. 国際誌 査読有り

    Sogi Y, Hagiwara Y, Yabe Y, Sekiguchi T, Momma H, Tsuchiya M, Kuroki K, Kanazawa K, Koide M, Itaya N, Yoshida S, Yano T, Itoi E, Nagatomi R

    BMC sports science, medicine & rehabilitation　10　13-13　2018年

    DOI： 10.1186/s13102-018-0102-8 　

    ISSN：2052-1847

  59. Osteofibrous dysplasia arising in the humerus: A case report. 国際誌 査読有り

    Shinichirou Yoshida, Munenori Watanuki, Kouu Hayashi, Masami Hosaka, Yoshihiro Hagiwara, Eiji Itoi, Masahito Hatori, Shin Hitachi, Mika Watanabe

    Rare tumors　10　2036361318808852-2036361318808852　2018年

    DOI： 10.1177/2036361318808852 　

    ISSN：2036-3605

    eISSN：2036-3613

  60. Coexistence of Trunk or Lower Extremity Pain with Elbow and/or Shoulder Pain among Young Overhead Athletes: A Cross-Sectional Study. 査読有り

    Takuya Sekiguchi, Yoshihiro Hagiwara, Haruki Momma, Masahiro Tsuchiya, Kaoru Kuroki, Kenji Kanazawa, Yutaka Yabe, Shinichiro Yoshida, Masashi Koide, Nobuyuki Itaya, Eiji Itoi, Ryoichi Nagatomi

    The Tohoku journal of experimental medicine　243　(3)　173-178　2017年11月

    DOI： 10.1620/tjem.243.173 　

    ISSN：0040-8727

  61. Association Between Sleep Disturbance and New-onset Subjective Shoulder Pain in Survivors of the Great East Japan Earthquake: A Prospective Cohort Study in Miyagi Prefecture 査読有り

    Yoshihiro Hagiwara, Takuya Sekiguchi, Yumi Sugawara, Yutaka Yabe, Masashi Koide, Nobuyuki Itaya, Shinichiro Yoshida, Yasuhito Sogi, Masahiro Tsuchiya, Ichiro Tsuji, Eiji Itoi

    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE　242　(3)　193-201　2017年7月

    DOI： 10.1620/tjem.242.193 　

    ISSN：0040-8727

    eISSN：1349-3329

  62. Adamantinoma Arising in the Distal End of the Fibula. 国際誌 査読有り

    Shinichirou Yoshida, Takashi Murakami, Kentarou Suzuki, Shigemi Itou, Munenori Watanuki, Masami Hosaka, Yoshihiro Hagiwara

    Rare tumors　9　(1)　6823-6823　2017年3月24日

    DOI： 10.4081/rt.2017.6823 　

    ISSN：2036-3605

    eISSN：2036-3613

  63. Evaluating the Biostability of Yellow and Clear Intraocular Lenses with a System Simulating Natural Intraocular Environment. 国際誌 査読有り

    Rijo Hayashi, Shimmin Hayashi, Kiyomi Arai, Shinichirou Yoshida, Makoto Chikuda, Shigeki Machida

    Translational vision science & technology　5　(6)　11-11　2016年12月

    ISSN：2164-2591

    詳細を見る 詳細を閉じる

    PURPOSE: Blue light-filtering intraocular lenses (IOLs) are thought to protect the retina from blue light damage after cataract surgery, and the implantation of yellow-tinted IOLs has been commonly used in cataract surgery. To our knowledge, this is the first investigation measuring the long-term biostability of yellow-tinted IOLs using an in vitro system simulating natural intraocular environment. METHODS: Six hydrophobic acrylic IOLs, three clear IOLs, and three yellow-tinted IOLs were included in the study. Each yellow-tinted IOL was a matching counterpart of a clear IOL, with the only difference being the lens color. The IOLs were kept in conditions replicating the intraocular environment using a perfusion culture system for 7 months. Resolution, light transmittance rate, and the modulation transfer function (MTF) were measured before and after culturing. Surface roughness of the anterior and posterior surfaces was also measured. RESULTS: After culturing for 7 months, there were no changes in the resolution, the light transmittance rate, and MTF. The surface roughness of the anterior and posterior surfaces increased after culturing; however, this increase was clinically insignificant. There were no differences in surface roughness between the clear and yellow-tinted IOLs, either before or after culturing. CONCLUSIONS: A novel in vitro system replicating intraocular environment was used to investigate the biostability of yellow-tinted IOLs. The surface roughness showed no clinically significant increase after culturing for 7 months. TRANSLATIONAL RELEVANCE: This system is useful for evaluating the biostability of IOLs.

  64. Proposed diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, 2015 version. 査読有り

    Yasufumi Masaki, Hiroshi Kawabata, Kazue Takai, Masaru Kojima, Norifumi Tsukamoto, Yasuhito Ishigaki, Nozomu Kurose, Makoto Ide, Jun Murakami, Kenji Nara, Hiroshi Yamamoto, Yoko Ozawa, Hidekazu Takahashi, Katsuhiro Miura, Tsutomu Miyauchi, Shinichirou Yoshida, Akihito Momoi, Nobuyasu Awano, Soichiro Ikushima, Yasunori Ohta, Natsue Furuta, Shino Fujimoto, Haruka Kawanami, Tomoyuki Sakai, Takafumi Kawanami, Yoshimasa Fujita, Toshihiro Fukushima, Shigeo Nakamura, Tomohiro Kinoshita, Sadao Aoki

    International journal of hematology　103　(6)　686-92　2016年6月

    DOI： 10.1007/s12185-016-1979-1 　

    詳細を見る 詳細を閉じる

    TAFRO syndrome is a systemic inflammatory disorder characterized by thrombocytopenia, anasarca including pleural effusion and ascites, fever, renal insufficiency, and organomegaly including hepatosplenomegaly and lymphadenopathy. Its onset may be acute or sub-acute, but its etiology is undetermined. Although several clinical and pathological characteristics of TAFRO syndrome resemble those of multicentric Castleman disease (MCD), other specific features can differentiate between them. Some TAFRO syndrome patients have been successfully treated with glucocorticoids and/or immunosuppressants, including cyclosporin A, tocilizumab and rituximab, whereas others are refractory to treatment, and eventually succumb to the disease. Early and reliable diagnoses and early treatments with appropriate agents are essential to enhancing patient survival. The present article reports the 2015 updated diagnostic criteria, disease severity classification and treatment strategy for TAFRO syndrome, as formulated by Japanese research teams. These criteria and classification have been applied and retrospectively validated on clinicopathologic data of 28 patients with this and similar conditions (e.g. MCD with serositis and thrombocytopenia).

  65. Numerical analysis of acoustic impedance microscope utilizing acoustic lens transducer to examine cultured cells 査読有り

    Agus Indra Gunawan, Naohiro Hozumi, Kenta Takahashi, Sachiko Yoshida, Yoshifumi Saijo, Kazuto Kobayashi, Seiji Yamamoto

    ULTRASONICS　63　102-110　2015年12月

    DOI： 10.1016/j.ultras.2015.06.016 　

    ISSN：0041-624X

    eISSN：1874-9968

  66. Numerical analysis of ultrasound propagation and reflection intensity for biological acoustic impedance microscope 査読有り

    Agus Indra Gunawan, Naohiro Hozumi, Sachiko Yoshida, Yoshifumi Saijo, Kazuto Kobayashi, Seiji Yamamoto

    ULTRASONICS　61　79-87　2015年8月

    DOI： 10.1016/j.ultras.2015.03.010 　

    ISSN：0041-624X

    eISSN：1874-9968

  67. Unstable mechanism of low T/W dynamical instability

    Motoyuki Saijo, Shin'ichirou Yoshida

    Proceedings of the 25th Workshop on General Relativity and Gravitation in Japan, JGRG 2015　3　642-648　2015年

    出版者・発行元： Kyoto University, Yukawa Institute for Theoretical Physics

  68. Acoustic impedance micro-imaging for biological tissue using a focused acoustic pulse with a frequency range up to 100 MHz 査読有り

    N Hozumi, A Kimura, S Terauchi, M Nagao, S Yoshida, K Kobayashi, Y Saijo

    2005 IEEE Ultrasonics Symposium, Vols 1-4　170-173　2005年

    DOI： 10.1109/ULTSYM.2005.1602823 　

    ISSN：1051-0117

︎全件表示 ︎最初の5件までを表示

MISC 74

  1. 当院における骨転移診療ボードの取り組みとその効果

    吉田新一郎, 岩津潤, 大野木孝嘉, 高橋康平, 橋本功, 相澤俊峰, 柳垣聡, 常陸真, 高瀬圭

    日本整形外科学会雑誌　97　(3)　2023年

    ISSN： 0021-5325

  2. 当院における骨転移診療ボードによる臨床面および若手教育面での効果

    吉田新一郎, 岩津潤, 大野木孝嘉, 高橋康平, 橋本功, 相澤俊峰, 柳垣聡, 常陸真, 小黒草太, 高瀬圭

    日本整形外科学会雑誌　97　(6)　2023年

    ISSN： 0021-5325

  3. 大腿骨遠位骨軟骨腫に合併した仮性動脈瘤により坐骨神経麻痺を来した1例

    石川圭佑, 吉田新一郎, 綿貫宗則

    日本整形外科学会雑誌　95　(6)　2021年

    ISSN： 0021-5325

  4. ラット膝関節不動化モデルにおける関節血腫は軟骨変性への影響

    曽木 靖仁, 萩原 嘉廣, 矢部 裕, 小野田 祥人, 関口 拓矢, 板谷 信行, 吉田 新一郎, 矢野 利尚, 鈴木 一瑛, 井樋 栄二

    日本整形外科学会雑誌　93　(8)　S1933-S1933　2019年9月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  5. 凍結肩の関節包における、RAGEによるNF-κB反応経路の活性化

    矢野 利尚, 萩原 嘉廣, 矢部 裕, 関口 拓矢, 小出 将志, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 鈴木 一瑛, 井樋 栄二

    日本整形外科学会雑誌　93　(8)　S1763-S1763　2019年9月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  6. On the central engine of the fastest-declining Type I supernova SN2019bkc

    Shin'ichirou Yoshida

    2019年7月31日

    詳細を見る 詳細を閉じる

    An analytic model is presented for the fastest-declining Type I supernova<br /> SN2019bkc. The model of the central engine consists of the magnetic dipole<br /> radiation from a non-explosive remnant of a double white dwarf merger. We<br /> consider the viscous evolution of the rotating remnant, which may lead to the<br /> diminishing energy supply in an appropriate time scale for the light curve.

  7. 骨巨細胞腫治療におけるdenosumabの意義 当科における骨巨細胞腫治療25年間のあゆみ Denosumabを使って分かったこと

    保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 矢野 利尚, 羽鳥 正仁, 土肥 修, 常陸 真, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1345-S1345　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  8. より安全な切除縁確保をめざして 超音波検査による表在性軟部肉腫反応層の評価

    綿貫 宗則, 保坂 正美, 吉田 新一郎, 矢野 利尚, 常陸 真, 渡辺 みか, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1490-S1490　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  9. 骨化性筋炎におけるzonal phenomenonの発生時期に関する検討

    矢野 利尚, 保坂 正美, 綿貫 宗則, 吉田 新一郎, 井樋 栄二, 林 耕宇, 渡辺 みか, 常陸 真

    東北整形災害外科学会雑誌　62　(1)　181-182　2019年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  10. 経過観察中に自然退縮したdeep juvenile xanthogranulomaの1例

    矢野 利尚, 保坂 正美, 綿貫 宗則, 吉田 新一郎, 渡辺 みか, 常陸 真, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1542-S1542　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  11. より安全な切除縁確保をめざして 超音波検査による表在性軟部肉腫反応層の評価

    綿貫 宗則, 保坂 正美, 吉田 新一郎, 矢野 利尚, 常陸 真, 渡辺 みか, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1490-S1490　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  12. 骨巨細胞腫治療におけるdenosumabの意義 当科における骨巨細胞腫治療25年間のあゆみ Denosumabを使って分かったこと

    保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 矢野 利尚, 羽鳥 正仁, 土肥 修, 常陸 真, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1345-S1345　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  13. 骨巨細胞腫治療におけるdenosumabの意義 当科における骨巨細胞腫治療25年間のあゆみ Denosumabを使って分かったこと

    保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 矢野 利尚, 羽鳥 正仁, 土肥 修, 常陸 真, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1345-S1345　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  14. より安全な切除縁確保をめざして 超音波検査による表在性軟部肉腫反応層の評価

    綿貫 宗則, 保坂 正美, 吉田 新一郎, 矢野 利尚, 常陸 真, 渡辺 みか, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1490-S1490　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  15. 経過観察中に自然退縮したdeep juvenile xanthogranulomaの1例

    矢野 利尚, 保坂 正美, 綿貫 宗則, 吉田 新一郎, 渡辺 みか, 常陸 真, 井樋 栄二

    日本整形外科学会雑誌　93　(6)　S1542-S1542　2019年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  16. 骨化性筋炎におけるzonal phenomenonの発生時期に関する検討

    矢野 利尚, 保坂 正美, 綿貫 宗則, 吉田 新一郎, 井樋 栄二, 林 耕宇, 渡辺 みか, 常陸 真

    東北整形災害外科学会雑誌　62　(1)　181-182　2019年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  17. スポーツ少年団員における睡眠習慣が腰痛に与える影響

    矢部裕, 萩原嘉廣, 吉田新一郎, 曽木靖仁, 矢野利尚, 大野木孝廣, 井樋栄二

    Journal of Spine Research　10　(3)　563-563　2019年3月25日

    出版者・発行元： (一社)日本脊椎脊髄病学会

    ISSN： 1884-7137

  18. 筋骨格系疼痛が新規不眠発生に与える影響―東日本大震災被災者における縦断調査―

    矢部裕, 萩原嘉廣, 関口拓矢, 板谷信行, 吉田新一郎, 曽木靖仁, 矢野利尚, 大野木孝嘉, 井樋栄二

    日本整形外科学会雑誌　93　(3)　S1259-S1259　2019年3月12日

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  19. スポーツ少年団における暴言・体罰を使用する指導者の特徴

    矢部 裕, 萩原 嘉廣, 関口 拓矢, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 矢野 利尚, 大野木 孝嘉, 井樋 栄二

    日本整形外科学会雑誌　93　(3)　S998-S998　2019年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  20. 筋骨格系疼痛が新規不眠発生に与える影響 東日本大震災被災者における縦断調査

    矢部 裕, 萩原 嘉廣, 関口 拓矢, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 矢野 利尚, 大野木 孝嘉, 井樋 栄二

    日本整形外科学会雑誌　93　(3)　S1259-S1259　2019年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  21. スポーツ少年団における暴言・体罰を使用する指導者の特徴

    矢部 裕, 萩原 嘉廣, 関口 拓矢, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 矢野 利尚, 大野木 孝嘉, 井樋 栄二

    日本整形外科学会雑誌　93　(3)　S998-S998　2019年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  22. スポーツ少年団員における睡眠習慣が腰痛に与える影響

    矢部 裕, 萩原 嘉廣, 吉田 新一郎, 曽木 靖仁, 矢野 利尚, 大野木 孝廣, 井樋 栄二

    Journal of Spine Research　10　(3)　563-563　2019年3月

    出版者・発行元： (一社)日本脊椎脊髄病学会

    ISSN： 1884-7137

    eISSN： 2435-1563

  23. 股関節可動域制限を来した外傷後骨化性筋炎に対し外科的切除を行なった1例

    佐藤貴也, 千葉大介, 桑原功行, 馬場一慈, 大泉樹, 保坂正美, 綿貫宗則, 吉田新一郎, 井樋栄二

    日本股関節学会学術集会プログラム・抄録集　46th　670　2019年

  24. Rotating white dwarf models with finite-temperature envelope

    Shin'ichirou Yoshida

    2018年12月28日

    DOI： 10.1093/mnras/stz1030 　

    詳細を見る 詳細を閉じる

    We present new numerical method to compute structures of differentially<br /> rotating white dwarfs with thermal stratification. Our models have cores<br /> composed of ions and completely degenerate electrons and have isentropic<br /> envelopes composed of ions, photons, partially degenerate electrons and<br /> positrons. The models are intended to mimic very early phases of remnants of<br /> white dwarf binary mergers, some of which may lead to type Ia supernovae. The<br /> effect of hot envelope to increase the mass depends on its chemical composition<br /> through the mean molecular weight of the envelope. For uniformly rotating<br /> models, we see only a small increase in mass even in the presence of hot<br /> envelope. Differential rotation changes it drastically and super-Chandrasekhar<br /> mass model whose mass doubles the Chandrasekhar mass of the degenerate star for<br /> some parameter choices. We also compute quasi-equilibrium evolutionary<br /> sequences of remnants by fixing either total angular momentum or entropy in the<br /> envelope. Existence of these sequences depends on various factors such as the<br /> remnant mass, the profile of differential rotation, the entropy and the<br /> chemical composition of the envelope.

  25. 20年以上長期観察した骨巨細胞腫肺転移の2例

    保坂正美, 綿貫宗則, 林耕宇, 吉田新一郎, 矢野利尚, 羽鳥正仁, 土肥修, 井樋栄二

    日本整形外科学会雑誌　92　(6)　S1587-S1587　2018年6月5日

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  26. 骨腫瘍掻爬術後の骨補填材による骨新生の検討

    吉田新一郎, 綿貫宗則, 矢野利尚, 保坂正美, 井樋栄二, 常陸真, 渡辺みか

    日本整形外科学会雑誌　92　(6)　S1582-S1582　2018年6月5日

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  27. 左下腿軟部腫瘍の1例

    矢野利尚, 保坂正美, 綿貫宗則, 林耕宇, 吉田新一郎, 井樋栄二, 渡辺みか, 常陸真

    日本整形外科学会雑誌　92　(6)　S1372-S1372　2018年6月5日

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  28. 骨化性筋炎におけるzonal phenomenonの発生時期と骨化巣の消退に関する検討

    矢野利尚, 矢野利尚, 保坂正美, 綿貫宗則, 吉田新一郎, 井樋栄二, 林耕宇, 渡辺みか, 常陸真

    日本整形外科学会雑誌　92　(6)　S1467-S1467　2018年6月5日

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  29. 骨・軟部腫瘍領域における悪性リンパ腫の初回病理組織診断

    綿貫宗則, 保坂正美, 吉田新一郎, 矢野利尚, 井樋栄二

    日本整形外科学会雑誌　92　(6)　S1451-S1451　2018年6月5日

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  30. 骨髄鏡を用いた掻爬を行った小児BCG骨髄炎の1例

    阿部 高久, 保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 井樋 栄二, 千本 英一, 笹原 洋二, 今泉 秀樹

    東北整形災害外科学会雑誌　61　(1)　186-187　2018年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  31. マウス筋機械痛覚過敏に対するIL-18の関与

    土谷 昌広, 吉田 新一郎, 萩原 嘉廣, 篠田 雅路, 小出 将志, 畠山 裕康, チャウイワンナコン・チャヤニ, 矢野 利尚, 曽木 靖仁, 板谷 信行, 関口 拓矢, 矢部 裕, 土谷 忍, 佐々木 啓一, 神崎 展, 井樋 栄二

    PAIN RESEARCH　33　(2)　160-160　2018年6月

    出版者・発行元： 日本疼痛学会

    ISSN： 0915-8588

  32. 骨・軟部腫瘍領域における悪性リンパ腫の初回病理組織診断

    綿貫 宗則, 保坂 正美, 吉田 新一郎, 矢野 利尚, 井樋 栄二

    日本整形外科学会雑誌　92　(6)　S1451-S1451　2018年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  33. マウス筋機械痛覚過敏に対するIL-18の関与

    土谷 昌広, 吉田 新一郎, 萩原 嘉廣, 篠田 雅路, 小出 将志, 畠山 裕康, チャウイワンナコン・チャヤニ, 矢野 利尚, 曽木 靖仁, 板谷 信行, 関口 拓矢, 矢部 裕, 土谷 忍, 佐々木 啓一, 神崎 展, 井樋 栄二

    PAIN RESEARCH　33　(2)　160-160　2018年6月

    出版者・発行元： 日本疼痛学会

    ISSN： 0915-8588

  34. マウス筋機械痛覚過敏に対するIL-18の関与

    土谷 昌広, 吉田 新一郎, 萩原 嘉廣, 篠田 雅路, 小出 将志, 畠山 裕康, チャウイワンナコン・チャヤニ, 矢野 利尚, 曽木 靖仁, 板谷 信行, 関口 拓矢, 矢部 裕, 土谷 忍, 佐々木 啓一, 神崎 展, 井樋 栄二

    PAIN RESEARCH　33　(2)　160-160　2018年6月

    出版者・発行元： 日本疼痛学会

    ISSN： 0915-8588

  35. 骨髄鏡を用いた掻爬を行った小児BCG骨髄炎の1例

    阿部 高久, 保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 井樋 栄二, 千本 英一, 笹原 洋二, 今泉 秀樹

    東北整形災害外科学会雑誌　61　(1)　186-187　2018年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  36. 左下腿軟部腫瘍の1例

    矢野 利尚, 保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 井樋 栄二, 渡辺 みか, 常陸 真

    日本整形外科学会雑誌　92　(6)　S1372-S1372　2018年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  37. 骨・軟部腫瘍領域における悪性リンパ腫の初回病理組織診断

    綿貫 宗則, 保坂 正美, 吉田 新一郎, 矢野 利尚, 井樋 栄二

    日本整形外科学会雑誌　92　(6)　S1451-S1451　2018年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  38. 骨化性筋炎におけるzonal phenomenonの発生時期と骨化巣の消退に関する検討

    矢野 利尚, 保坂 正美, 綿貫 宗則, 吉田 新一郎, 井樋 栄二, 林 耕宇, 渡辺 みか, 常陸 真

    日本整形外科学会雑誌　92　(6)　S1467-S1467　2018年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  39. 骨腫瘍掻爬術後の骨補填材による骨新生の検討

    吉田 新一郎, 綿貫 宗則, 矢野 利尚, 保坂 正美, 井樋 栄二, 常陸 真, 渡辺 みか

    日本整形外科学会雑誌　92　(6)　S1582-S1582　2018年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  40. 20年以上長期観察した骨巨細胞腫肺転移の2例

    保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 矢野 利尚, 羽鳥 正仁, 土肥 修, 井樋 栄二

    日本整形外科学会雑誌　92　(6)　S1587-S1587　2018年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  41. スポーツ少年団員における座位活動が腰痛に与える影響

    矢部 裕, 萩原 嘉廣, 関口 拓矢, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 矢野 利尚, 井樋 栄二

    Journal of Spine Research　9　(3)　572-572　2018年3月

    出版者・発行元： (一社)日本脊椎脊髄病学会

    ISSN： 1884-7137

  42. スポーツ少年団員における座位活動が腰痛に与える影響

    矢部 裕, 萩原 嘉廣, 関口 拓矢, 板谷 信行, 吉田 新一郎, 曽木 靖仁, 矢野 利尚, 井樋 栄二

    Journal of Spine Research　9　(3)　572-572　2018年3月

    出版者・発行元： (一社)日本脊椎脊髄病学会

    ISSN： 1884-7137

    eISSN： 2435-1563

  43. 小児動脈瘤様骨嚢腫に対する術中無水エタノール処理の有効性

    吉田 新一郎, 綿貫 宗則, 関口 拓矢, 林 耕宇, 保坂 正美, 井樋 栄二, 常陸 真, 渡辺 みか

    日本整形外科学会雑誌　91　(6)　S1267-S1267　2017年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  44. 初回医療機関受診から腫瘍専門病院受診までに長期間を要した軟部肉腫症例の検討

    綿貫 宗則, 保坂 正美, 林 耕宇, 吉田 新一郎, 井樋 栄二

    日本整形外科学会雑誌　91　(6)　S1294-S1294　2017年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  45. 足底に発生したdendritic fibromyxolipomaの1例

    矢野 利尚, 保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 井樋 栄二, 渡辺 みか, 常陸 真

    日本整形外科学会雑誌　91　(6)　S1417-S1417　2017年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  46. 初診時M1軟部肉腫の治療経験

    保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 井樋 栄二

    日本整形外科学会雑誌　91　(6)　S1435-S1435　2017年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  47. 神経症状を伴う脊椎転移に行った緊急放射線治療の検討

    鈴木 堅太郎, 吉田 新一郎, 村上 享, 藤本 圭佑, 佐藤 友美

    東北整形災害外科学会雑誌　60　(1)　227-227　2017年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  48. 学童期スポーツ選手の抱える膝痛に関連する因子の検討 宮城県スポーツ少年団アンケート調査(横断研究)

    板谷 信行, 萩原 嘉廣, 関口 拓矢, 矢部 裕, 金澤 憲治, 小出 将志, 吉田 新一郎, 矢野 利尚, 曽木 靖仁, 井樋 栄二

    JOSKAS　42　(4)　258-258　2017年5月

    出版者・発行元： (一社)日本関節鏡・膝・スポーツ整形外科学会

    ISSN： 1884-8842

  49. 日常よく見かける骨・軟部腫瘍に対するアプローチ 炎症を伴う腫瘤性疾患へのアプローチ 結節性筋膜炎・骨化性筋炎を中心に

    保坂 正美, 綿貫 宗則, 林 耕宇, 吉田 新一郎, 渡辺 みか, 常陸 真, 羽鳥 正仁, 井樋 栄二

    日本整形外科学会雑誌　91　(2)　S405-S405　2017年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  50. 術後下肢機能障害の克服 軟部肉腫広範切除後の残存四頭筋断面積の経時的変化 多施設共同後ろ向き研究

    綿貫 宗則, 保坂 正美, 吉田 新一郎, 秋山 達, 福島 崇, 岩田 慎太郎, 筑紫 聡, 井樋 栄二

    日本整形外科学会雑誌　91　(2)　S407-S407　2017年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  51. 東日本大震災被災者における主観的経済状況が肩こりに与える影響 前向きコホート研究

    関口 拓矢, 萩原 嘉廣, 矢部 裕, 菅原 由美, 丹治 文也, 遠又 靖丈, 小出 将志, 板谷 信行, 吉田 新一郎, 辻 一郎, 井樋 栄二

    日本整形外科学会雑誌　91　(3)　S810-S810　2017年3月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  52. 骨髄鏡を用いた掻爬を行った小児BCG骨髄炎の一例

    阿部高久, 阿部高久, 保坂正美, 綿貫宗則, 林耕宇, 吉田新一郎, 千本英一, 笹原洋二, 今泉秀樹, 井樋栄二

    東北整形災害外科学会プログラム・抄録集　114th　101　2017年

  53. On a role of corotation radius in the low $T/W$ dynamical instability of differentially rotating stars

    Shin'ichirou Yoshida, Motoyuki Saijo

    2016年11月30日

    DOI： 10.1093/mnras/stw3064 　

    詳細を見る 詳細を閉じる

    We investigate the nature of so-called low $T/W$ dynamical instability in a<br /> differentially rotating star by focusing on the role played by the corotation<br /> radius of the unstable oscillation modes. An one dimensional model of linear<br /> perturbation, which neglects dependence of variables on the coordinate along<br /> the rotational axis of the star, is solved to obtain stable and unstable<br /> eigenmodes. A linear eigenmode having a corotation radius, at which azimuthal<br /> pattern speed of the mode coincides with the stellar angular velocity, is<br /> categorized to either a complex (growing or damping) mode or a purely real mode<br /> belonging to a continuous spectrum of frequency. We compute canonical angular<br /> momentum and its flux to study eigenmodes with corotation radius. In a<br /> dynamically unstable mode, sound wave transports its angular momentum in such a<br /> way that the absolute value of the angular momentum is increased on both sides<br /> of the corotation radius. We further evaluate growth of amplitude of reflected<br /> sound wave incident to a corotation point and find that the over-reflection of<br /> the wave and the trapping of it between the corotation radius and the surface<br /> of the star may qualitatively explain dependences of eigenfrequencies on the<br /> stellar differential rotation. The results suggest that the low $T/W$<br /> instability may be caused by over-reflection of sound waves trapped mainly<br /> between the surface of the star and a corotation radius.

  54. Unstable normal modes of low T/W dynamical instabilities in differentially rotating stars

    Motoyuki Saijo, Shin'ichirou Yoshida

    PHYSICAL REVIEW D　94　(8)　2016年10月

    DOI： 10.1103/PhysRevD.94.084032 　

    ISSN： 2470-0010

    eISSN： 2470-0029

  55. 廃用萎縮・脂肪変性した筋組織中の筋・脂肪前駆細胞の分化能の評価

    小出 将志, 萩原 嘉廣, 矢部 裕, 安藤 晃, 金澤 憲治, 関口 拓矢, 板谷 信行, 吉田 新一郎, 神崎 展, 畠山 裕康, 土谷 昌広, 井樋 栄二

    日本整形外科学会雑誌　90　(8)　S1543-S1543　2016年8月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  56. 骨肉腫と血管肉腫の重複がんの一例

    鈴木 堅太郎, 高橋 徳明, 吉田 新一郎, 村上 享

    東北整形災害外科学会雑誌　59　(1)　220-221　2016年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  57. 骨梗塞に続発したsecondary undifferentiated pleomorphic sarcomaの1例

    吉田 新一郎, 村上 享, 鈴木 堅太郎, 伊藤 しげみ

    日本整形外科学会雑誌　90　(6)　S1271-S1271　2016年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  58. 距骨骨腫瘍の1例

    吉田 新一郎, 村上 享, 鈴木 堅太郎, 伊藤 しげみ

    日本整形外科学会雑誌　90　(6)　S1394-S1394　2016年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  59. 肩峰骨折に対し、踵骨用ロッキングプレートを用いた内固定を行った一例

    吉田 新一郎, 八田 卓久, 藤城 裕一, 佐藤 研, 矢部 裕, 中島 聡一, 本田 雅人

    東北整形災害外科学会雑誌　58　(1)　169-169　2015年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  60. 腰部脊柱管狭窄症に対するX-STOPの治療成績

    佐藤 研, 本田 雅人, 中島 聡一, 藤城 裕一, 吉田 新一郎, 矢部 裕

    東北整形災害外科学会雑誌　58　(1)　39-44　2015年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

    詳細を見る 詳細を閉じる

    腰部脊柱管狭窄症に対してeXtension STOP(X-STOP)による手術を行った5例6椎間の治療成績を検討した。対象は男4例・女1例、平均年齢69歳で、経過観察期間は術後6ヵ月間であった。手術高位は1椎間挿入はL2/3が1例、L3/4が1例、L4/5が2例、2椎間挿入はL3/4、L4/5が各1例であった。JOAスコアは術後全例改善し、改善率は術後1ヵ月で平均42%、術後6ヵ月で平均67%であった。補正椎間板高については、術後平均20%が術当日は平均27%と開大したが、術後1ヵ月には平均25%、術後6ヵ月には平均24%まで減少した。術後合併症は2例で認め、いずれも挿入椎間高位の棘突起骨折で術後1ヵ月後に診断された。2例とも他症例に比べ術後補正椎間板高が大きかった。

  61. 小児の脛骨近位に発生した間葉性軟骨肉腫の一例

    吉田 新一郎, 保坂 正美, 綿貫 宗則, 岸本 光司, 鈴木 堅太郎, 井樋 栄二, 服部 弘之, 高橋 徳明, 村上 享

    東北整形災害外科学会雑誌　57　(1)　153-153　2014年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

  62. 最近10年間の当科におけるLuque SSI法の経験

    吉田 新一郎, 小澤 浩司, 相澤 俊峰, 中村 豪, 菅野 晴夫, 小圷 知明, 井樋 栄二

    東北整形災害外科学会雑誌　57　(1)　15-19　2014年6月

    出版者・発行元： 東北整形災害外科学会

    ISSN： 1348-8694

    詳細を見る 詳細を閉じる

    最近10年間に当科でLuque SSI法を行った12例について検討した。疾患の内訳は、転移性脊椎腫瘍が5例、頸胸椎脱臼骨折が3例、原発性脊椎腫瘍が2例、破裂骨折後の遅発性麻痺が2例であった。Luque SSI法を用いた理由は、椎弓根が細いためが5例、転移性脊椎腫瘍のためが4例、頸椎のためが3例であった。固定範囲はSegmental sublaminar wiringを頭尾側各3に椎弓を行った例が9例、頸椎で各2に椎弓を行った例が3例であった。11例で最終経過観察時まで良好な固定が維持された。術後合併症は、1例で術後一時的に麻痺の増悪を認めたが、術後1ヵ月以内に改善した。また、1例でワイヤーの折損による後彎変形を認め、再手術を要した。

  63. HEY1-NCOA2 fusion geneの検出が診断に有用だった小児間葉性軟骨肉腫の1例

    吉田 新一郎, 保坂 正美, 綿貫 宗則, 岸本 光司, 鈴木 堅太郎, 井樋 栄二, 服部 弘之, 高橋 徳明, 村上 享, 渡辺 みか, 長谷川 匡, 常陸 真

    日本整形外科学会雑誌　88　(6)　S1247-S1247　2014年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  64. 上腕骨に発生したosteofibrous dysplasiaの1例

    吉田 新一郎, 保坂 正美, 綿貫 宗則, 林 耕宇, 鈴木 堅太郎, 岸本 光司, 井樋 栄二, 羽鳥 正仁, 渡辺 みか, 常陸 真

    日本整形外科学会雑誌　88　(6)　S1267-S1267　2014年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  65. Three-pin modified 'Harrington' procedureによる臼蓋再建を行った肝細胞癌転移の1例

    矢野 利尚, 保坂 正美, 山田 則一, 岸本 光司, 山本 宣幸, 綿貫 宗則, 千葉 大介, 永元 英明, 塩田 有規, 吉田 新一郎, 井樋 栄二, 中村 聡, 佐野 徳久

    日本整形外科学会雑誌　88　(6)　S1295-S1295　2014年6月

    出版者・発行元： (公社)日本整形外科学会

    ISSN： 0021-5325

  66. Assessment of Cowling approximation in computing ellipticity of a magnetized non-barotropic star

    Shin'ichirou Yoshida

    MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY　435　(1)　893-896　2013年10月

    DOI： 10.1093/mnras/stt1362 　

    ISSN： 0035-8711

    eISSN： 1365-2966

  67. 脛骨に発生した間葉性軟骨肉腫の1例

    吉田 新一郎, 保坂 正美, 綿貫 宗則, 岸本 光司, 鈴木 堅太郎, 井樋 栄二, 小沼 正栄, 笹原 洋二, 服部 弘之, 高橋 徳明, 村上 享, 渡辺 みか, 常陸 真

    日本小児血液・がん学会雑誌　50　(2)　280-281　2013年7月

    出版者・発行元： (一社)日本小児血液・がん学会

    ISSN： 2187-011X

  68. 脊椎術後感染に対するVAC(Vaccum-assisted wound closure)療法の使用経験

    吉田 新一郎, 黒澤 大輔, 村上 栄一, 小澤 浩司

    Journal of Spine Research　4　(3)　756-756　2013年3月

    出版者・発行元： (一社)日本脊椎脊髄病学会

    ISSN： 1884-7137

  69. Nonaxisymmetric oscillations of rapidly rotating relativistic stars by conformal flatness approximation

    Shin'ichirou Yoshida

    PHYSICAL REVIEW D　86　(10)　2012年11月

    DOI： 10.1103/PhysRevD.86.104055 　

    ISSN： 2470-0010

    eISSN： 2470-0029

  70. Clinico Pathological Conference 胃癌化学療法中に呼吸状態増悪し、死に至った1例

    吉田 新一郎, 黒木 実智雄, 松田 幹夫

    山形市立病院済生館医学雑誌　36　(1)　72-73　2011年8月

    出版者・発行元： 山形市立病院済生館医学雑誌編集委員会

    ISSN： 0385-1184

  71. Low T/|W| dynamical instability in differentially rotating stars: diagnosis with canonical angular momentum

    M Saijo, S Yoshida

    MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY　368　(3)　1429-1442　2006年5月

    DOI： 10.1111/j.1365-2966.2006.10229.x 　

    ISSN： 0035-8711

  72. Low T/|W| dynamical instabilities in differentially rotating stars: Diagnosis with canonical angular momentum

    Motoyuki Saijo, Shin'ichirou Yoshida

    2006年4月7日

    DOI： 10.1063/1.2399650 　

    詳細を見る 詳細を閉じる

    We study the nature of non-axisymmetric dynamical instabilities in<br /> differentially rotating stars with both linear eigenmode analysis and<br /> hydrodynamic simulations in Newtonian gravity. We especially investigate the<br /> following three types of instability; the one-armed spiral instability, the low<br /> T/|W| bar instability, and the high T/|W| bar instability, where T is the<br /> rotational kinetic energy and W is the gravitational potential energy. The<br /> nature of the dynamical instabilities is clarified by using a canonical angular<br /> momentum as a diagnostic. We find that the one-armed spiral and the low T/|W|<br /> bar instabilities occur around the corotation radius, and they grow through the<br /> inflow of canonical angular momentum around the corotation radius. The result<br /> is a clear contrast to that of a classical dynamical bar instability in high<br /> T/|W|. We also discuss the feature of gravitational waves generated from these<br /> three types of instability.

  73. Dynamical One-Armed Spiral Instability in Differentially Rotating Stars

    Motoyuki Saijo, Shin'ichirou Yoshida

    eConf C041213:1419,2005　2005年4月1日

    詳細を見る 詳細を閉じる

    We investigate the dynamical one-armed spiral instability in differentially<br /> rotating stars with both eigenmode analysis and hydrodynamic simulations in<br /> Newtonian gravity. We find that the one-armed spiral mode is generated around<br /> the corotation radius of the star, and the distribution of angular momentum<br /> shifts inwards the corotation radius during the growth of one-armed spiral<br /> mode. We also find by investigating the distribution of the canonical angular<br /> momentum density that the low T/|W| dynamical instability for both m=1 and m=2<br /> mode, where T is the rotational kinetic energy and W is the gravitational<br /> potential energy, is generated around the corotation point. Finally, we discuss<br /> the feature of gravitational waves generated from these modes.

  74. Rossby-Haurwitz waves of a slowly and differentially rotating fluid shell

    Luciano Rezzolla, Shin'ichirou Yoshida

    Class.Quant.Grav.18:L87,2001　2001年7月9日

    DOI： 10.1088/0264-9381/18/15/101 　

    詳細を見る 詳細を閉じる

    Recent studies have raised doubts about the occurrence of r modes in<br /> Newtonian stars with a large degree of differential rotation. To assess the<br /> validity of this conjecture we have solved the eigenvalue problem for<br /> Rossby-Haurwitz waves (the analogues of r waves on a thin-shell) in the<br /> presence of differential rotation. The results obtained indicate that the<br /> eigenvalue problem is never singular and that, at least for the case of a<br /> thin-shell, the analogues of r modes can be found for arbitrarily large degrees<br /> of differential rotation. This work clarifies the puzzling results obtained in<br /> calculations of differentially rotating axi-symmetric Newtonian stars.

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共同研究・競争的資金等の研究課題 3

  1. 次世代放射光を用いた下肢閉塞性動脈疾患における組織障害機序の解明

    鈴木 峻也, 梅津 道久, 赤松 大二朗, 芹澤 玄, 吉田 新一郎, 権田 幸祐

    提供機関：Japan Society for the Promotion of Science

    制度名：Grants-in-Aid for Scientific Research

    研究種目：Grant-in-Aid for Scientific Research (C)

    研究機関：Tohoku University

    2025年4月1日 ～ 2028年3月31日

  2. 好中球細胞外トラップの評価による骨軟部肉腫のバイオマーカーと新規治療開発

    吉田 新一郎

    2024年4月1日 ～ 2027年3月31日

  3. メタボローム解析による骨軟部肉腫のバイオマーカー探索

    吉田 新一郎

    2020年4月1日 ～ 2023年3月31日

    詳細を見る 詳細を閉じる

    骨軟部肉腫は骨や軟部組織に発生する非上皮性悪性腫瘍で、多くの組織型が存在する。同一の組織型でも病勢や予後が異なることがあるため、病勢把握や予後予測に有効なバイオマーカーの確立が急務である。代謝産物はセントラルドグマの下流にあるため上流の遺伝子やタ ンパクよりも表現型に近く、バイオマーカーとして有用とされている。そのため、代謝経路・代謝産物を網羅的に解析するメタボロームを用いたバイオマーカー探索が有用である。 しかしながら骨軟部肉腫については、実際の患者サンプルでのメタボローム解析の報告はない。本研究の目的は、メタボローム解析を用いて骨軟部肉腫のバイオマーカーの探索を行うことである。手術で摘出した骨軟部肉腫のサンプルをメタボローム解析することでその代謝経路の変化や増加・減少する代謝産物を確認し、さらに患者情報や術後経過との関連を評価することで、予後予測の指標となるバイオマーカーを明らかにする。 骨軟部肉腫の手術は月に2-4件のペースで継続的に行っており、現在は患者情報や患者サンプルの採取・症例の集積を行っている。具多的には対象症例の臨床情報をデータベース化し、登録している。また対象症例の標本を集積し、保管している。しかしながら、骨軟部肉腫は稀少疾患のため、同一の組織型のサンプルが複数集まるのには時間を要する。今後も一定以上のペースで症例の集積は期待できるため、同一組織型を複数（統計解析可能な症例数）を集積すべく集積を続けている。