Details of the Researcher

PHOTO

Keita Abe
Section
Graduate School of Engineering
Job title
Assistant Professor
e-Rad No.
00982860

Research History 3

  • 2024/04 - Present
    Tohoku University Graduate School of Engineering Department of Robotics

  • 2023/04 - 2024/03
    Tohoku University Graduate School of Engineering Department of Robotics

  • 2019/04 - 2022/03
    Japan Society for the Promotion of Science

Education 2

  • Tohoku University Graduate School of Engineering Department of Robotics

    2017/04 - 2023/03

  • Tohoku University Faculty of Engineering Department of Mechanical and Aerospace Engineering

    2013/04 - 2017/03

Research Interests 3

  • パターン形成

  • 反応拡散系

  • DNAナノテクノロジー

Papers 10

  1. Reversible Photocontrol of mRNA Synthesis and Cleavage for mRNA Concentration Switching Inside Artificial Cells

    Daichi Iwata, Keiji Murayama, Ken Komiya, Hideaki T Matsubayashi, Keita Abe, Hiroyuki Asanuma, Satoshi Murata, Shin-Ichiro M Nomura

    2026/03/03

    Publisher: American Chemical Society (ACS)

    DOI: 10.26434/chemrxiv.15000569/v1  

  2. Intra- and Interbead Communications by an Anchored DNA Structure and Cascaded DNA Reactions Peer-reviewed

    Ibuki Kawamata, Satoru Yoshizawa, Keita Abe, Masahiro Takinoue, Shin-Ichiro M. Nomura, Satoshi Murata

    ACS Synthetic Biology 2025/03/14

    Publisher: American Chemical Society (ACS)

    DOI: 10.1021/acssynbio.4c00709  

    ISSN: 2161-5063

    eISSN: 2161-5063

  3. Programming Pattern Formation by DNA Reaction-diffusion System with Designed Base Sequences

    Keita ABE, Satoshi MURATA, Ibuki KAWAMATA

    Seibutsu Butsuri 65 (1) 14-16 2025

    Publisher: Biophysical Society of Japan

    DOI: 10.2142/biophys.65.14  

    ISSN: 0582-4052

    eISSN: 1347-4219

  4. Transmembrane DNA Sequence Signaling via Hybridization

    Kai Yoshida, Keita Abe, Yusuke Sato, Ibuki Kawamata, Richard James Archer, Hideaki T. Matsubayashi, Shogo Hamada, Satoshi Murata, Shin-ichiro Nomura

    2024/07/16

    DOI: 10.26434/chemrxiv-2024-571kp  

  5. Online Biomolecular Design Competition Across University Boundaries Peer-reviewed

    Satoshi MURATA, Akinori KUZUYA, Kei FUJIWARA, Junichi TAIRA, Ibuki KAWAMATA, Yusuke SATO, Masahiro TAKINOUE, Shin-ichiro M. NOMURA, Akira KAKUGO, Yutaka HORI, Keita ABE

    Journal of JSEE 69 (4) 31-39 2021

    Publisher: Japanese Society for Engineering Education

    DOI: 10.4307/jsee.69.4_31  

    ISSN: 1341-2167

    eISSN: 1881-0764

  6. Cascaded pattern formation in hydrogel medium using the polymerisation approach Peer-reviewed

    Keita Abe, Satoshi Murata, Ibuki Kawamata

    Soft Matter 2021

    Publisher: Royal Society of Chemistry ({RSC})

    DOI: 10.1039/D1SM00296A  

  7. Programming Methods for DNA-Based Reaction–Diffusion Systems Peer-reviewed

    Keita Abe, Satoshi Murata

    New Generation Computing 38 (2) 379-393 2020/05

    Publisher: Springer Science and Business Media {LLC}

    DOI: 10.1007/s00354-020-00094-z  

    ISSN: 0288-3635 1882-7055

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    <jats:title>Abstract</jats:title><jats:p>In this tutorial, recent development of pattern generation algorithms based on DNA computing will be overviewed. Natural pattern generation, especially in biological organisms, are often driven by spatio-temporal chemical reactions. Various reaction–diffusion systems have been proposed to generate artificial patterns out of DNA sequences. To program DNA reaction–diffusion systems, in addition to the design of the reaction, diffusion of each DNA species must be considered. This is realized by immobilizing or suppressing diffusion of DNA molecules in the reaction field. Here, several typical methods to build patterns by 1-D or 2-D reaction–diffusion systems are introduced and how to implement the system by DNA molecules is explained. The direction of future research and possible applications of this technology will be also discussed.</jats:p>

  8. Programmable reactions and diffusion using DNA for pattern formation in hydrogel medium Peer-reviewed

    Keita Abe, Ibuki Kawamata, Shin-ichiro M. Nomura, Satoshi Murata

    Molecular Systems Design & Engineering 2019

    Publisher: Royal Society of Chemistry ({RSC})

    DOI: 10.1039/C9ME00004F  

  9. Diffusion modulation of DNA by toehold exchange Peer-reviewed

    Thanapop Rodjanapanyakul, Fumi Takabatake, Keita Abe, Ibuki Kawamata, Shinichiro M. Nomura, Satoshi Murata

    Physical Review E 97 (5) 2018/05/31

    Publisher: American Physical Society ({APS})

    DOI: 10.1103/physreve.97.052617  

    ISSN: 2470-0045 2470-0053

  10. Revolving Vernier Mechanism Controls Size of Linear Homomultimer Peer-reviewed

    Takeo Uchida, Keita Abe, Yuma Endo, Shosei Ichiseki, Satoru Akita, Shiyun Liu, Sho Aradachi, Masataka Saito, Akihiko Fukuchi, Taiyo Kikkawa, Theo Dammaretz, Ibuki Kawamata, Yuki Suzuki, Shin-ichiro M. Nomura, Satoshi Murata

    Small 13 (41) 1702158-1702158 2017/11

    Publisher: Wiley

    DOI: 10.1002/smll.201702158  

    ISSN: 1613-6810

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Research Projects 3

  1. New development of spatio-temporal molecular programming

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (A)

    Institution: Tohoku University

    2020/04/01 - 2025/03/31

  2. DNA反応拡散系を用いた自己区画化システムの構築と機能化

    安部 桂太

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 研究活動スタート支援

    Institution: 東北大学

    2023/08 - 2025/03

  3. DNA反応拡散系による階層的なパターンの形成と制御および形態形成への発展

    安部 桂太

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業 特別研究員奨励費

    Category: 特別研究員奨励費

    Institution: 東北大学

    2019/04 - 2022/03

    More details Close

    本研究はDNAの相互作用により反応拡散系を構築し,階層的なパターン形成を実現させること,そして形成させたDNAの濃度勾配パターンを形態形成に発展させ,パターン形状に応じたハイドロゲルを構築することで自己組織化による人工物の作製方法を確立することを目的としている.申請時の計画では,本年度は2年目までに構築したパターン形成技術を発展させた形態形成技術の開発を予定していた. 本年度は前年度報告時点で確立したパターン形成の手法を用いた実験結果を整理し,さらにシミュレーション結果と比較した.その成果は現在学術論文としてRoyal Society of Chemistryが企画する雑誌Soft Matterへ投稿し,現在オープンアクセス論文として公開されている.また,この成果に関して複数の国際学会で報告し,研究の発展へ向けた情報収集と意見交換を行った. さらに,目標としていた形態形成手法への発展のため実験系,材料,ゲル化や拡散制御の手法等のさらなる検討とシミュレーション・実験を重ねた.結果として,拡散の制御やDNAハイドロゲルといった既存の技術との組み合わせによる発展の可能性を調査するとともに,その実証に必要な新たな検証を可能にする実験系を構築することに成功した. よって本年度は,目標としていた形態形成技術の実現はかなわなかったものの,これまでの実験結果を広く周知して情報交換と新たな手法の検討に尽力し,形態形成技術へと発展させるうえで有用となりうる研究成果が得られた.