Details of the Researcher

PHOTO

Yuriko Goto
Section
Tohoku University Hospital
Job title
Assistant Professor
Degree

  • Doctor of dental medicine (Iwate Medical University)

e-Rad No.
60908672

Research History 2

  • 2026/04 - Present
    東北大学病院　病院（歯科診療部門）周術期口腔健康管理部　診療助教

  • 2021/04 - 2026/03
    Tohoku University Hospital　Dental Hospital

Education 1

  • Iwate Medical University　Graduate School of Dental Science　Oral Pathology

    2016/04 - 2020/03

Professional Memberships 4

  • 口腔内科学会

    2025/04 - Present

  • 日本口腔外科学会

  • 歯科基礎医学会

  • 日本病理学会

Research Interests 3

  • エナメル上皮腫

  • 唾液腺腫瘍

  • 腫瘍組織発生

Research Areas 1

  • Life sciences / Oral medicine / Oral pathology

Awards 1

  1. ベストペーパー賞

    2021/10　一般社団法人 歯科基礎医学会

Papers 3

  1. Immunohistochemical assessment of LGR5 and LGR6 in solid and unicystic ameloblastomas

    Yuriko Goto, Pawat Sripodok, Akihito Kumei, Takashi Nishioka, Masahiro Iikubo, Yuji Hatakeyama, Hiroyuki Kumamoto

    Journal of Oral and Maxillofacial Surgery, Medicine and Pathology　2026/04

  2. 全顎的な歯髄腔の狭窄がみられたステロイド長期使用患者のエックス線画像 Peer-reviewed

    渡辺尚子, 横山由加, 小嶋郁穂, 嶋田雄介, 後藤弓里子, 泉田一賢, 熊坂晃, 飯久保正弘

    歯科放射線　62　(1)　39-42　2022/01

    Publisher: (NPO)日本歯科放射線学会

    ISSN： 0389-9705

    eISSN： 2185-6311

  3. PLAG1 enhances the stemness profiles of acinar cells in normal human salivary glands in a cell type-specific manner. International-journal Peer-reviewed

    Yuriko Goto, Miho Ibi, Hirotaka Sato, Junichi Tanaka, Rika Yasuhara, Keiko Aota, Masayuki Azuma, Toshiyuki Fukada, Kenji Mishima, Tarou Irié

    Journal of oral biosciences　62　(1)　99-106　2020/03

    DOI： 10.1016/j.job.2020.01.002 　

    More details Close

    OBJECTIVES: Details of the histogenesis of salivary gland tumors are largely unknown. The oncogenic role of PLAG1 in the salivary gland has been demonstrated in vivo. Herein, we demonstrate PLAG1 roles in the acinar and ductal cells of normal human salivary glands to clarify the early events that occur during the histogenesis of salivary gland tumors. METHODS: Normal salivary gland cells with acinar and ductal phenotypes were transfected with PLAG1 plasmid DNA. Subsequently, PLAG1 overexpressed and mock cells were examined by cell proliferation, transwell migration, and salisphere formation assays. Differentiation and salivary and pluripotent stem cell marker expression levels were evaluated by quantitative reverse transcription-polymerase chain reaction and immunofluorescence. Alterations in transcriptional expressions were investigated via cap analysis of gene expression with gene-enrichment and functional annotation analysis. RESULTS: PLAG1 promoted cell proliferation and transwell migration in the acinar and ductal cells, and markedly enhanced the stemness profiles and luminal cell-like profiles in acinar cells; the stemness profiles were partially increased in the ductal cells. CONCLUSION: PLAG1 enhanced the stemness profiles in the acinar cells of normal human salivary glands in a cell type-specific manner. Thus, it may be involved in salivary gland tumorigenesis by increasing the stemness character of the normal salivary gland cells.

Misc. 2

  1. A case of sialadenitis after administration of pembrolizumab

    Yuriko Goto, Akihito Kumei, Eri Hataoka, Yumiko Sugawarara, Masahiro Iikubo, Hiroyuki Kumamoto

    Proceedings of the Japanese Society of Pathology　第114　(1)　390-390　2025/04

  2. 唾液腺腫瘍組織発生機構の解明

    森 弓里子, 衣斐 美歩, 佐藤 泰生, 入江 太朗

    岩手医科大学歯学雑誌　44　(1)　26-26　2019/06

Presentations 8

  1. 心臓移植後のエベロリムス投与中に発症した口内炎の１例

    新垣理宣, 宝金由訓, 後藤弓里子, 丹田奈緒子

    第４１回日本栄養治療学会学術集会　2026/02/13

  2. 長期に血中IgG４が高値を示したシェーグレン症候群の１症例

    畑岡英里, 菅原由美子, 小嶋郁穂, 嶋田雄介, 後藤弓里子, 熊本裕行, 飯久保正弘

    第37回NPO法人日本口腔科学会近畿地方部会　2025/12/06

  3. A case of irAE with severe xerostomia that required differentiation from Sjogren's syndrome

    Yuriko Goto, Yumiko Sugawara, Akihito Kumei, Eri Hataoka, Ikuho Kojima, Hiroyuki Kumamoto, Masahiro Iikubo

    2025/09/07

  4. A case of sialadenitis as an irAE of pembrolizumab therapy

    Yuriko Goto, Akihito Kumei, Eri Hataoka, Yumiko Sugawarara, Masahiro Iikubo, Hiroyuki Kumamoto

    The 114th Annual Meeting of the Japanese Society of Pathology　2025/04/18

  5. LGR5 and 6 Expression in Ameloblastoma

    Yuriko Goto, Pawat Sripodok, Masahiro Iikubo, Hiroyuki Kumamoto

    The 113th Annual Meeting of the Japanese Society of Pathology　2024/03

  6. 新型コロナウィルス感染拡大に伴う周術期口腔管理患者の動向

    熊坂 晃, 後藤弓里子, 泉田一賢, 飯久保正弘

    第４回国際歯科医療安全機構総会・学術大会　2021/11/23

  7. 顎顔面補綴治療における嚥下透視検査の有用性

    泉田一賢, 熊坂 晃, 後藤弓里子, 小山重人, 佐々木啓一, 飯久保正弘

    日本歯科放射線学会 第232回関東地方会・第40回北日本地方会・第28回合同地方会　2021/08/21

  8. PLAG1 enhances the stemness profiles of acinar cells in normal human salivary glands in a cell-type specific manner

    Yuriko Goto, Miho Ibi, Hirotaka Sato, Junichi Tanaka, Rika Yasuhara, Keiko Aota, Masayuki Azuma, Toshiyuki Fukada, Kenji Mishima, Tarou Irie

    2020/07

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Research Projects 1

  1. エナメル上皮腫における幹細胞的性格が腫瘍の発症・再発に及ぼす影響

    後藤 弓里子

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究

    Institution: 東北大学

    2024/04/01 - 2027/03/31