Details of the Researcher

PHOTO

Yuri Takeda
Section
Graduate School of Dentistry
Job title
Assistant Professor
Degree

  • 博士（医学）（東北大学）

Papers 24

  1. Relationship of preoperative serum data with MRONJ patient postoperative course – Retrospective study

    Yuri Takeda, Yushi Ezoe, Yuka Iwamae, Tai Kimura, Kenya Tomitsuka, Shinki Koyama, Kazuhiro Imoto, Hiromitsu Morishima, Shinnosuke Nogami, Kensuke Yamauchi

    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology　2025/09

    DOI： 10.1016/j.ajoms.2025.02.006 　

  2. Application of navigation system during surgery for medication-related osteonecrosis of the jaw

    Yuri Takeda, Yuka Iwamae, Shizu Saito, Yushi Ezoe, Shinnosuke Nogami, Kensuke Yamauchi

    Journal of the Korean Association of Oral and Maxillofacial Surgeons　2025/06/30

    DOI： 10.5125/jkaoms.2025.51.3.174 　

  3. Clinical course of masticatory function recovery following endoscopic-assisted open reduction and internal fixation in patients with unilateral mandibular condyle fracture. International-journal

    Shinnosuke Nogami, Yushi Ezoe, Yuri Takeda, Yoshio Otake, Hiromitsu Morishima, Kensuke Yamauchi

    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery　53　(3)　245-249　2025/03

    DOI： 10.1016/j.jcms.2024.12.005 　

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    The purpose of this study was to investigate the clinical course of masticatory function recovery following an endoscopic-assisted open reduction and internal fixation (EAORIF) procedure. Patients with a unilateral mandibular condylar fracture who underwent EAORIF for therapeutic purposes were evaluated, with comparisons made between those who underwent the procedure for base or neck fractures. At each time point analyzed after treatment, the occlusal contact area and maximum bite force in patients with a base fracture were greater, although the differences between the groups were not significant. Moreover, at 12 months following EAORIF for a base fracture, occlusal contact area and maximum bite force on the fractured and non-fractured sides were nearly equal, whereas these were significantly reduced in the fractured as compared with the non-fractured side in patients who underwent that treatment for a neck fracture. Additionally, after 12 months in the neck fracture cases, both occlusal contact area and maximum bite force on the fractured side were lower as compared with those on the non-fractured side. These findings indicate that EAORIF is an optimal method for base fracture treatment with regard to masticatory function.

  4. Novel electromagnetic-navigated maxillary repositioning system for Le Fort I osteotomy: preclinical evaluation

    Shizu Saito, Kyosuke Okuyama, Yuri Takeda, Shinnosuke Nogami, Nobuhiro Yoda, Masanori Hariyama, Kensuke Yamauchi

    British Journal of Oral and Maxillofacial Surgery　2024/10

    DOI： 10.1016/j.bjoms.2024.10.231 　

  5. 口内法より筋突起切除を行ったJacob's diseaseの1例

    安田 寛, 武田 裕利, 大竹 義雄, 黒田 佳奈子, 野上 晋之介, 熊本 裕行, 山内 健介

    日本口腔科学会雑誌　73　(3)　264-264　2024/09

    Publisher: (NPO)日本口腔科学会

    ISSN： 0029-0297

    eISSN： 2185-0461

  6. Surgery-early approach combined with condylectomy for correction of severe facial asymmetry with mandibular condylar hyperplasia: a case report

    Hikari Suzuki, Shinnosuke Nogami, Yoshio Otake, Yuri Takeda, Junji Sugawara, Tetsu Takahashi, Kensuke Yamauchi

    Journal of the Korean Association of Oral and Maxillofacial Surgeons　2024/08/31

    DOI： 10.5125/jkaoms.2024.50.4.227 　

  7. Survey on the usefulness and satisfaction of telemedicine for maxillofacial and oral surgery Peer-reviewed

    Yuri Takeda, Norihisa Satomi, Yushi Ezoe, Hiromitsu Morishima, Hitoshi Miyashita, Atsumu Kouketsu, Shinnosuke Nogami, Tsuyoshi Sugiura, Kensuke Yamauchi

    Tohoku Univ. Dent. J.　42　75-86　2024/08

  8. 上顎に生じた巨大な歯牙腫の1例

    深瀬 了嗣, 大竹 義雄, 権 寧洸, 武田 裕利, 野上 晋之介, 纐纈 衆, 宮下 仁, 熊本 裕行, 杉浦 剛, 山内 健介

    日本口腔科学会雑誌　73　(1)　32-32　2024/03

    Publisher: (NPO)日本口腔科学会

    ISSN： 0029-0297

    eISSN： 2185-0461

  9. 下顎智歯抜歯後に下顎骨骨折を認めた2例

    齊藤 志都, 梶田 倫功, 鈴木 飛佳理, 大竹 義雄, 森島 浩允, 武田 裕利, 野上 晋之介, 山内 健介

    口腔顎顔面外傷　22　(2)　128-128　2023/12

    Publisher: 日本口腔顎顔面外傷学会

    ISSN： 1347-9903

  10. 歯科口腔外科外来で全身管理を要した重度化学物質過敏症患者の2症例

    下田 元, 佐藤 実, 宮下 仁, 岩間 亮介, 北村 淳, 大竹 義雄, 黒羽根 壮, 黒田 佳奈子, 高山 慎騎, 奥山 喬介, 阿部 陽子, 森島 浩允, 武田 裕利, 野上 晋之介, 佐藤 秀樹, 高橋 哲, 山内 健介

    東北大学歯学雑誌　42　(2)　97-107　2023/12

    Publisher: 東北大学歯学会

    ISSN： 0287-3915

  11. 植込み型補助人工心臓装着患者の口腔外科外来周術期管理に関する臨床的評価

    下田 元, 奥山 喬介, 佐藤 実, 宮下 仁, 岩間 亮介, 北村 淳, 大竹 義雄, 黒羽根 壮, 高山 慎騎, 森島 浩允, 武田 裕利, 野上 晋之介, 高橋 哲, 山内 健介

    東北大学歯学雑誌　42　(2)　121-121　2023/12

    Publisher: 東北大学歯学会

    ISSN： 0287-3915

  12. パノラマX線画像から中頭蓋窩左側部の病変を指摘できた線維性異形成症の1例

    横山 由加, 渡辺 尚子, 小嶋 郁穂, 嶋田 雄介, 菅井 優生, 武田 裕利, 千葉 雅俊, 高橋 哲, 飯久保 正弘

    歯科放射線　62　(2)　99-103　2023/03

    Publisher: (NPO)日本歯科放射線学会

    ISSN： 0389-9705

    eISSN： 2185-6311

  13. 上顎智歯抜歯時に生じた上顎骨骨折を契機に扁桃周囲膿瘍をきたした1例

    奥山 喬介, 野上 晋之介, 武田 裕利, 黒羽根 壮, 鈴木 飛佳理, 山内 健介, 高橋 哲

    口腔顎顔面外傷　21　(2)　27-32　2022/10

    Publisher: 日本口腔顎顔面外傷学会

    ISSN： 1347-9903

  14. Clinical course of masticatory function recovery following arthrocentesis in patients with unilateral mandibular condyle head fracture. International-journal

    Shinnosuke Nogami, Kensuke Yamauchi, Kuniyuki Izumita, Jun Kitamura, Yuri Takeda, Yoshio Otake, Shinki Koyama, Kyosuke Okuyama, Keiichi Sasaki, Tetsu Takahashi

    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery　50　(3)　225-229　2022/03

    DOI： 10.1016/j.jcms.2021.12.005 　

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    The aim of this study was to investigate the clinical course of masticatory function recovery following arthrocentesis. Patients with a unilateral condylar head fracture who underwent arthrocentesis for therapeutic reasons were evaluated and compared with patients with a unilateral condylar head fracture who did not undergo arthrocentesis. At 3 months after treatment, the occlusal contact area and maximum bite force in patients with a fracture treated with arthrocentesis were greater than in those who did not receive arthrocentesis at the same time points, although the differences were not significant. Moreover, at 1 and 3 months following arthrocentesis, mean (±SD) occlusal contact area (1 month: 1.99 ± 0.55 mm2, p = 0.01; 3 months: 2.90 ± 1.36 mm2, p = 0.03) and maximum bite force (1 month: 82.45 ± 15.04 N, p = 0.01; 3 months: 101.11 ± 14.53 N, p = 0.01) on the fractured side in patients who underwent that treatment were significantly reduced when compared with those on the non-fractured side. The authors conclude that if the priority is to avoid open reduction and internal fixation, then the arthrocentesis approach might be a less invasive alternative, albeit with the price of a prolonged healing interval.

  15. Low level gap arthroplasty using ultrasonic bone-cutting device for recurrent temporomandibular joint ankylosis – Case report

    Yoshio Otake, Shinnosuke Nogami, Masatoshi Chiba, Kenji Odashima, Yuri Takeda, Hitoshi Miyashita, Hirokazu Nagai, Kensuke Yamauchi, Tetsu Takahashi

    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology　2022

    DOI： 10.1016/j.ajoms.2022.04.002 　

    ISSN： 2212-5558

  16. 上顎智歯抜歯時に生じたと考えられた上顎骨骨折後の顎下部蜂巣炎の一例

    奥山 喬介, 野上 晋之介, 大竹 義雄, 森島 浩允, 武田 裕利, 黒羽根 壮, 鈴木 飛佳理, 山内 健介, 高橋 哲

    口腔顎顔面外傷　20　(2)　49-49　2021/10

    Publisher: 日本口腔顎顔面外傷学会

    ISSN： 1347-9903

  17. A case report: Spindle cell lipoma in the floor of mouth

    Yuri Takeda, Shinnosuke Nogami, Ryosuke Iwama, Hiromitsu Morishima, Kyosuke Okuyama, Shinki Koyama, Hitoshi Miyashita, Kensuke Yamauchi, Hiroyuki Kumamoto, Tetsu Takahashi

    Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology　32　(4)　323-329　2020/07

    DOI： 10.1016/j.ajoms.2020.03.006 　

    ISSN： 2212-5558

  18. 唾石を契機に発見された顎下部脂肪腫の一例

    森島 浩允, 武田 裕利, 野上 晋之介, 片岡 良浩, 宮下 仁, 山内 健介, 永井 宏和, 熊本 裕行, 高橋 哲

    東北大学歯学雑誌　37/38/39　(2/1-2/1)　33-39　2020/06

    Publisher: 東北大学歯学会

    ISSN： 0287-3915

  19. Relationship between arthroscopic findings of synovitis and levels of tumour necrosis factor-alpha and matrix metalloproteinases in synovial lavage fluid from patients with unilateral high mandibular condyle fractures

    S. Nogami, T. Takahashi, K. Yamauchi, Y. Takeda, K. Ito, M. Chiba, A. Gaggl

    Journal of Oral Rehabilitation　45　(6)　452-458　2018/06

    DOI： 10.1111/joor.12632 　

    ISSN： 0305-182X

    eISSN： 1365-2842

  20. Clinical evaluations of complete autologous fibrin glue, produced by the CryoSeal® FS system, and polyglycolic acid sheets as wound coverings after oral surgery. International-journal

    Atsumu Kouketsu, Shinnosuke Nogami, Minami Yamada-Fujiwara, Hirokazu Nagai, Kensuke Yamauchi, Shiro Mori, Hitoshi Miyashita, Tadashi Kawai, Aritsune Matsui, Yoshihiro Kataoka, Norihisa Satomi, Yushi Ezoe, Satoko Abe, Yuri Takeda, Takeshi Tone, Bunnichi Hirayama, Tsuyoshi Kurobane, Kazuki Tashiro, Yuta Yanagisawa, Tetsu Takahashi

    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery　45　(9)　1458-1463　2017/09

    DOI： 10.1016/j.jcms.2017.06.004 　

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    The CryoSeal® FS System has been recently introduced as an automated device for the production of complete fibrin glue from autologous plasma, rather than from pool allogenic or cattle blood, to prevent viral infection and allergic reaction. We evaluated the effectiveness of complete autologous fibrin glue and polyglycolic acid (PGA) sheet wound coverings in mucosa defect oral surgery. Postoperative pain, scar contracture, ingestion, tongue dyskinesia, and postoperative bleeding were evaluated in 12 patients who underwent oral (including the tongue) mucosa excision, and received a PGA sheet and an autologous fibrin glue covering. They were compared with 12 patients who received a PGA sheet and commercial allogenic fibrin glue. All cases in the complete autologous fibrin glue group demonstrated good wound healing without complications such as local infection or incomplete cure. All evaluated clinical measures in this group were similar or superior to the commercial allogenic fibrin glue group. Coagulation and adhesion quality achieved with this method was comparable to that with a PGA sheet and commercial fibrin glue. Covering oral surgery wounds with complete autologous fibrin glue produced by an automated device was convenient, safe, and reduced the risk of viral infection and allergic reaction associated with conventional techniques.

  21. TRAV7-2*02 Expressing CD8⁺ T Cells Are Responsible for Palladium Allergy. International-journal

    Yuri Takeda, Yoshiko Suto, Koyu Ito, Wataru Hashimoto, Tadashi Nishiya, Kyosuke Ueda, Takayuki Narushima, Tetsu Takahashi, Kouetsu Ogasawara

    International journal of molecular sciences　18　(6)　2017/05/31

    DOI： 10.3390/ijms18061162 　

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    While metallic biomaterials have led to an improvement in the quality of life, metal allergies, especially to palladium (Pd), has caused a recent increase in allergic patients. Metal allergy is known to be a T cell-mediated delayed-type hypersensitivity (DTH); however, the pathogenic T cell subsets and the specific T cell receptor (TCR) have not been identified. Therefore, we attempted to identify the pathogenic T cells responsible for Pd allergy. We found that activating CD8⁺ T cells significantly increased and that the TRAV (TCRα variable) 7-2*02 chain skewed in Pd allergic mice. Furthermore, adoptive transfer experiments revealed that in vitro-cultured Pd-stimulated antigen presenting cells (APCs) function as memory APCs with recipient mice developing Pd allergy and that the frequency of TRAV7-2*02 increases the same as conventional Pd allergic mice. In contrast, neither proliferation of CD8⁺ T cells nor increasing of TRAV7-2*02 was observed in major histocompatibility complex I (MHC I)-deficient Pd-APCs transferred to mice. Taken together, we revealed that TRAV7-2*02-expressing CD8⁺ T cells are the pathogenic T cells for the development of Pd allergy. We also identified the CDR3 consensus motif of pathogenic TCRs as CAAXSGSWQLIF in TRAV7-2*02/TRAJ (TCRα junction)22*01 positive cells. These results suggest that the specific TCRs represent novel targets for the development of diagnostics and treatments for metal allergy.

  22. The antihistamine olopatadine regulates T cell activation in palladium allergy. International-journal

    Naohiko Iguchi, Yuri Takeda, Naoki Sato, Kenichirou Ukichi, Akira Katakura, Kyosuke Ueda, Takayuki Narushima, Shigehito Higuchi, Kouetsu Ogasawara

    International immunopharmacology　35　70-76　2016/06

    DOI： 10.1016/j.intimp.2016.03.021 　

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    Because of its corrosion resistance palladium (Pd) has been widely used in many consumer products ranging from fashion accessories to dental materials. Recently, however, an increase in Pd allergy cases has been reported. Metal allergy is categorized as a Type IV allergy, which is characterized as a delayed-type hypersensitivity reaction in which T cells are known to play an important role; however, the precise mechanism of their action remains unclear. Here we defined the relationship between histamine and the Pd allergic reaction specifically with respect to T cell responses. To verify the effects of histamine on T cells, we examined whether there is a change in IFN-γ production following stimulation of histamine or the antihistamine, olopatadine hydrochloride (OLP), in vitro. In addition, we assessed whether OLP administration affected the degree of footpad swelling or IFN-γ production during the Pd allergy response in mice. We found that histamine stimulation increased IFN-γ production in T cells, specifically enhancing IFN-γ production in CD8(+) T cells compared with CD4(+) T cells. Interestingly, OLP suppressed the production of IFN-γ in CD8(+) T cells, and this compound inhibited footpad swelling and IFN-γ production in mice with Pd allergy. These results suggest that histamine promotes the Type IV allergic reaction and thus, the histamine 1 receptor (H1R) might be useful therapeutic target for treatment of metal allergy.

  23. Pathological analysis of metal allergy to metallic materials Peer-reviewed

    Mitsuko Kawano, Yuri Takeda, Kouetsu Ogasawara

    Springer Series in Biomaterials Science and Engineering　3　305-321　2015

    Publisher: Springer New York LLC

    DOI： 10.1007/978-3-662-46836-4_13 　

    ISSN： 2195-0652 2195-0644

  24. NKG2D⁺ IFN-γ⁺ CD8⁺ T cells are responsible for palladium allergy. International-journal

    Mitsuko Kawano, Masafumi Nakayama, Yusuke Aoshima, Kyohei Nakamura, Mizuho Ono, Tadashi Nishiya, Syou Nakamura, Yuri Takeda, Akira Dobashi, Akiko Takahashi, Misato Endo, Akiyo Ito, Kyosuke Ueda, Naoki Sato, Shigehito Higuchi, Takeru Kondo, Suguru Hashimoto, Masamichi Watanabe, Makoto Watanabe, Tetsu Takahashi, Keiichi Sasaki, Masanori Nakamura, Takehiko Sasazuki, Takayuki Narushima, Ryuji Suzuki, Kouetsu Ogasawara

    PloS one　9　(2)　e86810　2014

    DOI： 10.1371/journal.pone.0086810 　

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    Nickel, cobalt, and chromium are well known to be causal agents of allergic contact dermatitis. Palladium (Pd) can also cause allergic disease and exposure results from wide use of this metal in dental restorations and jewelry. Metal allergy is categorized as a delayed-type hypersensitivity, and metal-responsive T cell clones have been isolated from allergic patients. However, compared to nickel, little is known about the pathology of allergic disease mediated by Pd, and pathogenic T cells are poorly understood. To identify the pathogenic T cells that are responsible for onset of Pd allergy, we enriched metal-responsive lymphocytes by sequential adoptive transfer of involved lymph node cells. Here we show that sequential adoptive transfer gradually increased the incidence and the intensity of Pd allergy, and CD8⁺ T cells are responsible for the disease as CD8⁺ T cell-depleted mice and β2-microglobulin-deficient mice did not develop Pd allergy. In addition, we found that draining lymph node cells skewed toward CD8⁺ T cells in response to Pd challenge in 8th adoptive transferred recipient mice. The CD8⁺ T cells expressed NKG2D, a costimulatory molecule involved in the production of IFN-γ. NKG2D ligand was also induced in Pd-injected tissues. Furthermore, both NKG2D ligand-transgenic mice, where NKG2D is downmodulated, and IFN-γ-deficient mice showed impaired Pd allergy. Taken together, these results indicate that IFN-γ-producing NKG2D⁺ CD8⁺ T cells are responsible for Pd allergy and suggest that NKG2D is a potential therapeutic target for treatment of metal allergy.

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Misc. 23

  1. 宮城県内における薬剤関連顎骨壊死患者の治療・マネジメントの実態

    鈴木飛佳理, 武田裕利, 里見徳久, 木村太, 高山慎騎, 大竹義雄, 森島浩允, 野上晋之介, 杉浦剛, 山内健介

    日本口腔科学会学術集会プログラム・抄録集　77th　2023

  2. リンパ球数は薬剤関連顎骨壊死に対する外科的治療の予後予測因子となりうる

    武田 裕利, 永井 宏和, 森島 浩允, 鈴木 飛佳理, 大竹 義雄, 高山 慎騎, 宮下 仁, 山内 健介, 高橋 哲

    日本口腔科学会雑誌　71　(2)　138-138　2022/07

    Publisher: (NPO)日本口腔科学会

    ISSN： 0029-0297

    eISSN： 2185-0461

  3. 当科におけるAYA世代口腔癌患者に関する臨床的検討

    柳沢 佑太, 三浦 桂一郎, 宮下 仁, 纐纈 衆, 梶田 倫功, 武田 裕利, 森 士朗, 野上 晋之介, 山内 健介, 永井 宏和, 熊本 裕行, 高橋 哲

    頭頸部癌　48　(2)　220-220　2022/05

    Publisher: (一社)日本頭頸部癌学会

    ISSN： 1349-5747

    eISSN： 1881-8382

  4. A Case of Peritonsillar Abscess Triggered by a Maxillary Fracture During Extraction of a Maxillary Wisdom Tooth

    奥山喬介, 野上晋之介, 武田裕利, 黒羽根壮, 鈴木飛佳理, 山内健介, 高橋哲

    口腔顎顔面外傷　21　(2)　2022

    ISSN： 1347-9903

  5. 当科で薬剤性顎骨壊死の発症予防のため抜歯施行した患者の臨床的統計

    江副 祐史, 高山 慎騎, 武田 裕利, 山内 健介, 永井 宏和, 高橋 哲

    日本口腔科学会雑誌　69　(2)　75-75　2020/07

    Publisher: (NPO)日本口腔科学会

    ISSN： 0029-0297

  6. 当科における過去5年間の口腔扁平上皮癌NO症例の臨床的検討

    武田裕利, 宮下仁, 北村淳, 齊藤志都, 黒田佳奈子, 森士朗, 山内健介, 永井宏和, 高橋哲

    日本口腔腫瘍学会総会・学術大会プログラム・抄録集　38th　2020

  7. 肩甲骨による下顎再建後にPCBMとTIME法を用いて広範囲顎骨支持型装置を応用した一例

    森島 浩允, 片岡 良浩, 井本 和宏, 武田 裕利, 山内 健介, 高橋 哲

    Japanese Journal of Maxillo Facial Implants　18　(3)　167-167　2019/11

    Publisher: (公社)日本顎顔面インプラント学会

    ISSN： 1347-894X

    eISSN： 2433-5509

  8. 【口腔環境と全身のクロストーク】歯科金属アレルギーの予防・診断・治療に向けた疾患特異的T細胞の同定

    伊藤 甲雄, 武田 裕利, 小笠原 康悦

    炎症と免疫　27　(6)　469-473　2019/10

    Publisher: (株)先端医学社

    ISSN： 0918-8371

  9. 当科における過去5年間の口腔扁平上皮癌N0症例の臨床的検討

    武田裕利, 黒羽根壮, 宮下仁, 纐纈衆, 纐纈衆, 北村淳, 斎藤博紀, 田代和樹, 柳沢佑太, 井本和宏, 黒田佳奈子, 齊藤志都, 森士朗, 永井宏和, 山内健介, 高橋哲

    頭頸部癌　45　(2)　2019

    ISSN： 1349-5747

  10. 後期高齢者口腔癌症例の臨床学的検討

    武田裕利, 宮下仁, 黒羽根壮, 田代和樹, 川井忠, 野上晋之介, 北村淳, 纐纈衆, 齊藤博紀, 齊藤志都, 黒田佳奈子, 小川武則, 大越明, 石田英一, 森士朗, 山内健介, 永井宏和, 高橋哲

    日本口腔腫瘍学会総会・学術大会プログラム・抄録集　37th　2019

  11. A case of temporomandibular ankylosis associated with ankylosing spondylitis treated by arthroplasty

    IWAMA Ryosuke, NOGAMI Shinnosuke, YOKOTA Sou, TAKEDA Yuri, YAMAUCHI Kensuke, TAKAHASHI Tetsu

    Japanese Journal of Oral and Maxillofacial Surgery　64　(10)　582-587　2018

    Publisher: Japanese Society of Oral and Maxillofacial Surgeons

    DOI： 10.5794/jjoms.64.582 　

    ISSN： 0021-5163

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    <p>Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by inflammation and ankylosis of the axial skeleton. Initial symptoms often include lumbosacral pain with limited range of motion. Temporomandibular joint (TMJ) disorders are found in 3.0% to 20.5% of all cases of AS. However, cases of AS associated with TMJ ankylosis are rarely reported.</p><p> This report describes a 66-year-old male patient who was given a diagnosis of AS accompanied by bilateral TMJ ankylosis. The patient had a medical history of AS for approximately 30 years. The patient was referred for examination because he could only open his mouth a maximum of 5 mm. Computed tomographic images showed no TMJ space and revealed a bony mass causing ankylosis of the osseous components of both temporomandibular joints. Magnetic resonance imaging revealed sclerosis of the bone marrow in the condyles, and the articular disk was not visible. Bone scintigraphy revealed involvement of the spine, sacroiliac joints, right knee, bilateral elbows, and both acromioclavicular joints.</p><p> This report describes the clinical treatment and management of TMJ ankylosis in a patient with AS. The postoperative course has been uneventful for 3 years, and the maximum mouth opening has increased to 40 mm without any complications.</p>

  12. 片側性習慣性顎関節脱臼に対して超音波切削器具を用いた関節結節削除術の治療経験

    野上 晋之介, 山内 健介, 樋口 景介, 阿部 陽子, 武田 裕利, 蔡 優広, 山口 佳宏, 千葉 雅俊, 高橋 哲

    東北大学歯学雑誌　35/36　(2/1)　86-90　2017/06

    Publisher: 東北大学歯学会

    ISSN： 0287-3915

  13. 金属記憶抗原提示細胞の同定

    武田 裕利, 小笠原 康悦, 井口 直彦, 高橋 哲

    日本口腔科学会雑誌　65　(2)　175-175　2016/07

    Publisher: (NPO)日本口腔科学会

    ISSN： 0029-0297

  14. 東北大学病院歯科顎口腔外科における顎関節・咀嚼筋の疾患患者(骨折を除く)に関する後ろ向き調査 外科的療法を施行した患者動向について

    野上 晋之介, 樋口 景介, 山内 健介, 阿部 陽子, 山口 佳宏, 武田 裕利, 蔡 優広, 千葉 雅俊, 高橋 哲

    日本顎関節学会雑誌　28　(Suppl.)　121-121　2016/07

    Publisher: (一社)日本顎関節学会

    ISSN： 0915-3004

    eISSN： 1884-4308

  15. Identification of the pathogenic T cell in metal allergy

    64　(3)　270-274　2015/09

    Publisher: (有)科学評論社

    ISSN： 1881-1930

  16. パラジウムアレルギーにかかわるIFN-γ産生CD8+T細胞

    武田 裕利, 小笠原 康悦, 井口 直彦, 山口 佳宏, 高橋 哲

    日本口腔科学会雑誌　64　(2)　164-164　2015/07

    Publisher: (NPO)日本口腔科学会

    ISSN： 0029-0297

  17. Identification of the Pathogenic T Cells that Induce Metal Allergy

    33　(2)　140-143　2015/04

    Publisher: 日本バイオマテリアル学会 ; 2002-

    ISSN： 1347-7080

  18. A case report of tracheostomy following phlegmon by peri-implantitis

    68　(2)　23-28　2014/04

    Publisher: 九州歯科学会

    ISSN： 0368-6833

    eISSN： 1880-8719

  19. Approach for Development of Novel Biomaterials Based on Immunological Analysis

    Kawano Mitsuko, Takeda Yuri, Nakamura Sho, Ogasawara Kouetsu

    Materia Japan　53　(4)　153-156　2014

    Publisher: The Japan Institute of Metals and Materials

    DOI： 10.2320/materia.53.153 　

    ISSN： 1340-2625

  20. 共振周波数解析装置によるインプラント埋入時における安定性評価の検討

    田中 謙光, 横田 聡, 武田 裕利, 依田 信裕, 野上 晋之介, 高橋 哲

    Japanese Journal of Maxillo Facial Implants　12　(3)　181-181　2013/11

    Publisher: (公社)日本顎顔面インプラント学会

    ISSN： 1347-894X

  21. グロー放電処理と紫外線照射処理とチタン表面への初期細胞接着への影響の比較

    平山 聞一, 後藤 哲哉, 武田 裕利, 田中 謙光, 宮本 郁也, 小林 繁, 高橋 哲

    九州歯科学会雑誌　66　(5)　167-168　2012/10

    Publisher: 九州歯科学会

    ISSN： 0368-6833

    eISSN： 1880-8719

  22. 生体活性型アパタイトコートヒアルロン酸による骨誘導能をもつ注入型骨補填材料の開発

    高橋 哲, 武田 裕利, 平山 聞一, 田中 謙光, 後藤 哲哉, 小林 繁, 西原 達次

    九州歯科学会雑誌　66　(5)　178-179　2012/10

    Publisher: 九州歯科学会

    ISSN： 0368-6833

    eISSN： 1880-8719

  23. 生体活性型ヒアルロン酸-アパタイトハイブリッドによる骨誘導能をもつ注入型骨補填材料の開発

    高橋 哲, 武田 裕利, 平山 聞一, 田中 謙光, 後藤 哲哉, 小林 繁, 西原 達次

    九州歯科学会雑誌　66　(補冊)　43-43　2012/04

    Publisher: 九州歯科学会

    ISSN： 0368-6833

    eISSN： 1880-8719

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Presentations 6

  1. 上顎智歯抜歯時に生じたと考えられた上顎骨骨折後の顎下部蜂巣炎の一例

    奥山 喬介, 野上 晋之介, 大竹 義雄, 森島 浩允, 武田 裕利, 黒羽根 壮, 鈴木 飛佳理, 山内 健介, 高橋 哲

    口腔顎顔面外傷　2021/10

  2. 当科における骨代謝調節薬投与患者に対する外科処置の臨床的検討

    高山 慎騎, 永井 宏和, 佐藤 舜, 井本 和宏, 森島 浩允, 武田 裕利, 江副 祐史, 高橋 哲

    日本口腔科学会雑誌　2021/07

  3. 口蓋粘膜の腫脹を契機に発見された急性前骨髄性白血病の1例

    梶田 倫功, 宮下 仁, 纐纈 衆, 武田 裕利, 三浦 桂一郎, 野上 晋之介, 山内 健介, 永井 宏和, 高橋 哲

    頭頸部癌　2021/05

  4. 舌扁平上皮癌における頸部リンパ節転移に関する臨床統計学的検討

    三浦 桂一郎, 宮下 仁, 黒田 佳奈子, 佐藤 舜, 梶田 倫功, 纐纈 衆, 武田 裕利, 森 士朗, 野上 晋之介, 山内 健介, 永井 宏和, 高橋 哲

    頭頸部癌　2021/05

  5. 腓骨再建後のインプラント治療において歯槽骨造成用チタンメッシュとテンティングスクリューを併用した骨造成法の臨床的検討

    井本 和宏, 山内 健介, 森島 浩允, 武田 裕利, 片岡 良浩, 高橋 哲

    Japanese Journal of Maxillo Facial Implants　2020/11

  6. 当科で薬剤性顎骨壊死の発症予防のため抜歯施行した患者の臨床的統計

    江副 祐史, 高山 慎騎, 武田 裕利, 山内 健介, 永井 宏和, 高橋 哲

    日本口腔科学会雑誌　2020/07

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Research Projects 2

  1. 薬剤関連顎骨壊死におけるリンパ球系細胞の免疫応答の解明

    武田 裕利

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究

    Institution: 東北大学

    2022/04/01 - 2026/03/31

  2. Production of the transgenic cell lines and the transgenic mice with the T cell receptor specific for palladium allergy

    Takeda Yuri

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Early-Career Scientists

    Institution: Tohoku University

    2018/04/01 - 2022/03/31

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    Metals are used as medical biomaterials, but the number of patients with palladium (Pd) metal allergies has been increasing recently. However, the mechanism of onset of metal allergy is still unknown, and no fundamental treatment method has been established. Therefore, I focused on pathogenic T cells that react with metals, and aimed to clarify the molecular mechanism of antigen presentation in metal allergies. Specifically, I decided to product transgenic cell lines and transgenic mice using Pd allergy-specific T cell receptor (TCR) α chains. I believe that these can be used to help establish metal material safety tests and to elucidate the mechanism of the onset of metal allergies in vivo.