Details of the Researcher

PHOTO

Takeaki Imamura
Section
Graduate School of Medicine
Job title
Assistant Professor
Degree

  • 博士（医学）（東京大学）

Research Interests 2

  • COVID-19

  • SARS-CoV-2

Papers 40

  1. Molecular analysis of influenza A(H3N2) in a remote tropical island during 2014-2019 to identify the frequency of introduction and local circulation Peer-reviewed

    Sikandar Azam, Takeaki Imamura, Michiko Okamoto, Yusuke Sayama, Mayuko Saito, Mariko Saito-Obata, Clyde Dapat, Raita Tamaki, Christina Dahlia Joboco, Joanna Ina Manalo, Samantha Louise Bado, Joanne De Jesus Cornejo, Socorro Lupisan, Marianette Inobaya, Veronica Tallo, Beatriz P Quiambao, Hitoshi Oshitani

    International Journal of Infectious Diseases　2025/05

    DOI： 10.1016/j.ijid.2025.107864 　

  2. Norovirus-associated diarrhea and asymptomatic infection in children aged under 4 years: a community-cohort study in the Philippines Peer-reviewed

    Chuyao Yu, Maria Carmen A. Corpuz, Joseph M. Bonifacio, Makiko Kishi, Takeaki Imamura, Yusuke Sayama, Mariko Saito-Obata, Clyde Dapat, Michiko Okamoto, Hitoshi Oshitani, Mayuko Saito

    IJID Regions　2025/03

    DOI： 10.1016/j.ijregi.2024.100549 　

  3. Characterization of human respiratory syncytial virus in children with severe acute respiratory infection before and during the COVID-19 pandemic Peer-reviewed

    Paul Simusika, Michiko Okamoto, Clyde Dapat, Walter Muleya, Moffat Malisheni, Sikandar Azam, Takeaki Imamura, Mayuko Saito, Innocent Mwape, Evans Mpabalwani, Mwaka Monze, Hitoshi Oshitani

    IJID Regions　2024/06

    DOI： 10.1016/j.ijregi.2024.03.009 　

  4. Time-varying overdispersion of SARS-CoV-2 transmission during the periods when different variants of concern were circulating in Japan. International-journal Peer-reviewed

    Yura K Ko, Yuki Furuse, Kanako Otani, Masato Yamauchi, Kota Ninomiya, Mayuko Saito, Takeaki Imamura, Alex R Cook, Tadayuki Ahiko, Shunji Fujii, Yoshiharu Mori, Emiko Suzuki, Keiko Yamada, Yoshikazu Ashino, Hidetoshi Yamashita, Yuichi Kato, Katsumi Mizuta, Motoi Suzuki, Hitoshi Oshitani

    Scientific reports　13　(1)　13230-13230　2023/08/14

    DOI： 10.1038/s41598-023-38007-x 　

    More details Close

    Japan has implemented a cluster-based approach for coronavirus disease 2019 (COVID-19) from the pandemic's beginning based on the transmission heterogeneity (overdispersion) of severe acute respiratory coronavirus 2 (SARS-CoV-2). However, studies analyzing overdispersion of transmission among new variants of concerns (VOCs), especially for Omicron, were limited. Thus, we aimed to clarify how the transmission heterogeneity has changed with the emergence of VOCs (Alpha, Delta, and Omicron) using detailed contact tracing data in Yamagata Prefecture, Japan. We estimated the time-varying dispersion parameter ([Formula: see text]) by fitting a negative binomial distribution for each transmission generation. Our results showed that even after the emergence of VOCs, there was transmission heterogeneity of SARS-CoV-2, with changes in [Formula: see text] during each wave. Continuous monitoring of transmission dynamics is vital for implementing appropriate measures. However, a feasible and sustainable epidemiological analysis system should be established to make this possible.

  5. オルソミクソウイルス科 人獣共通感染症としてのインフルエンザと新たなパンデミックの可能性

    今村剛朗, 押谷仁

    臨床と微生物　50　(4)　2023/07/25

  6. Transmission of COVID-19 in Nightlife, Household, and Health Care Settings in Tokyo, Japan, in 2020 Peer-reviewed

    Takeaki Imamura, Aika Watanabe, Yusuke Serizawa, Manami Nakashita, Mayuko Saito, Mayu Okada, Asamoe Ogawa, Yukiko Tabei, Yoshiko Soumura, Yoko Nadaoka, Naoki Nakatsubo, Takashi Chiba, Kenji Sadamasu, Kazuhisa Yoshimura, Yoshihiro Noda, Yuko Iwashita, Yuji Ishimaru, Naomi Seki, Kanako Otani, Tadatsugu Imamura, Matthew Myers Griffith, Kelly DeToy, Motoi Suzuki, Michihiko Yoshida, Atsuko Tanaka, Mariko Yauchi, Tomoe Shimada, Hitoshi Oshitani

    JAMA Network Open　6　(2)　e230589-e230589　2023/02/24

    Publisher: American Medical Association (AMA)

    DOI： 10.1001/jamanetworkopen.2023.0589 　

    eISSN： 2574-3805

    More details Close

    Importance There have been few studies on the heterogeneous interconnection of COVID-19 outbreaks occurring in different social settings using robust, surveillance epidemiological data. Objectives To describe the characteristics of COVID-19 transmission within different social settings and to evaluate settings associated with onward transmission to other settings. Design, Setting, and Participants This is a case series study of laboratory-confirmed COVID-19 cases in Tokyo between January 23 and December 5, 2020, when vaccination was not yet implemented. Using epidemiological investigation data collected by public health centers, epidemiological links were identified and classified into 7 transmission settings: imported, nightlife, dining, workplace, household, health care, and other. Main Outcomes and Measures The number of cases per setting and the likelihood of generating onward transmissions were compared between different transmission settings. Results Of the 44 054 confirmed COVID-19 cases in this study, 25 241 (57.3%) were among male patients, and the median (IQR) age of patients was 36 (26-52) years. Transmission settings were identified in 13 122 cases, including 6768 household, 2733 health care, and 1174 nightlife cases. More than 6600 transmission settings were detected, and nightlife (72 of 380 [18.9%]; P < .001) and health care (119 [36.2%]; P < .001) settings were more likely to involve 5 or more cases than dining, workplace, household, and other settings. Nightlife cases appeared in the earlier phase of the epidemic, while household and health care cases appeared later. After adjustment for transmission setting, sex, age group, presence of symptoms, and wave, household and health care cases were less likely to generate onward transmission compared with nightlife cases (household: adjusted odds ratio, 0.03; 95% CI, 0.02-0.05; health care: adjusted odds ratio, 0.57; 95% CI, 0.41-0.79). Household settings were associated with intergenerational transmission, while nonhousehold settings mainly comprised transmission between the same age group. Among 30 932 cases without identified transmission settings, cases with a history of visiting nightlife establishments were more likely to generate onward transmission to nonhousehold settings (adjusted odds ratio, 5.30 [95% CI, 4.64-6.05]; P < .001) than those without such history. Conclusions and Relevance In this case series study, COVID-19 cases identified in nightlife settings were associated with a higher likelihood of spreading COVID-19 than household and health care cases. Surveillance and interventions targeting nightlife settings should be prioritized to disrupt COVID-19 transmission, especially in the early stage of an epidemic.

  7. 【新型コロナウイルスと闘う最前線】COVID-19の疫学的特徴と自治体公開情報を用いた解析

    今村 剛朗, 仁宮 洸太, 押谷 仁

    BIO Clinica　37　(13)　1168-1172　2022/12

    Publisher: (株)北隆館

    ISSN： 0919-8237

  8. Case Report: Spontaneous Postpartum Quadruple Cervicocephalic Arterial Dissection With a Heterozygous COL5A1 Variant of Unknown Significance Peer-reviewed

    Takeaki Imamura, Takaki Omura, Nobuo Sasaki, Satoshi Arino, Haruna Nohara, Akira Saito, Maki Ichinose, Kazumasa Yamaguchi, Naoki Kojima, Hiroshi Inagawa, Katsutoshi Takahashi, Toshiyuki Unno, Hiroko Morisaki, Osamu Ishikawa, Gakushi Yoshikawa, Yasusei Okada

    Frontiers in Neurology　13　2022/07/12

    Publisher: Frontiers Media {SA}

    DOI： 10.3389/fneur.2022.928803 　

    ISSN： 1664-2295

    More details Close

    <jats:p>Pregnancy-associated cervicocephalic arterial dissection is rare, and its pathophysiology remains poorly understood. Despite the hypothesized contribution to pathogenesis, connective tissue diseases and genetic factors are rarely identified in clinical cases. We describe a case of postpartum arterial dissection involving all four cervicocephalic arteries resulting in acute cerebral infarction. The patient underwent successful endovascular thrombectomy and angioplasty and recovered fully without sequelae. Genetic screening for connective tissue diseases identified a heterozygous missense <jats:italic>COL5A1</jats:italic> variant with unknown clinical significance. Two genetically related family members later developed arterial abnormalities, and one of them tested positive for the same <jats:italic>COL5A1</jats:italic> gene variant as our patient, while the other was scheduled for genetic testing. The extensive clinical presentation of our patient and the prevalence of arterial abnormalities in her family warrant further assessment of the association between the identified <jats:italic>COL5A1</jats:italic> gene variant and the pathogenesis of arterial dissections.</jats:p>

  9. Epidemiological Factors Associated with COVID-19 Clusters in Medical and Social Welfare Facilities. Peer-reviewed

    Tadatsugu Imamura, Yura K Ko, Yuki Furuse, Takeaki Imamura, Kazuaki Jindai, Reiko Miyahara, Eiichiro Sando, Ikkoh Yasuda, Naho Tsuchiya, Mayuko Saito, Motoi Suzuki, Hitoshi Oshitani

    Japanese journal of infectious diseases　75　(3)　281-287　2022/05/24

    DOI： 10.7883/yoken.JJID.2021.288 　

    More details Close

    The characteristics of coronavirus disease 2019 (COVID-19) clusters in medical and social welfare facilities and the factors associated with cluster size are still not yet fully understood. We reviewed COVID-19 cases in Japan identified from January 15 to April 30, 2020 and analyzed the factors associated with cluster size in medical and social welfare facilities. In this study, COVID-19 clusters were identified in 56 medical and 34 social welfare facilities. The number of cases in those facilities peaked after the peak of the general population. The duration of occurrence of new cases in clusters was positively correlated with the number of cases in both types of facilities (rho = 0.44, P < 0.001; and rho = 0.69, P < 0.001, respectively). However, the number of days between the first case in a prefecture and the onset of clusters was negatively correlated with the number of cases only in clusters in social welfare facilities (rho = - 0.4, P = 0.004). Our results suggest that COVID-19 cases in those facilities were prevalent in the latter phase of the disease's community transmission, although the underlying mechanisms for such a trend could differ between medical and social welfare facilities.

  10. Secondary transmission of SARS-CoV-2 during the first two waves in Japan: Demographic characteristics and overdispersion International-journal Peer-reviewed

    Yura K Ko, Yuki Furuse, Kota Ninomiya, Kanako Otani, Hiroki Akaba, Reiko Miyahara, Tadatsugu Imamura, Takeaki Imamura, Alex R Cook, Mayuko Saito, Motoi Suzuki, Hitoshi Oshitani

    International Journal of Infectious Diseases　116　365-373　2022/01

    Publisher: Elsevier BV

    DOI： 10.1016/j.ijid.2022.01.036 　

    ISSN： 1201-9712

    More details Close

    OBJECTIVES: Super-spreading events caused by overdispersed secondary transmission are crucial in the transmission of COVID-19. However, the exact level of overdispersion, demographics, and other factors associated with secondary transmission remain elusive. In this study, we aimed to elucidate the frequency and patterns of secondary transmission of SARS-CoV-2 in Japan. METHODS: We analyzed 16,471 cases between January 2020 and August 2020. We generated the number of secondary cases distribution and estimated the dispersion parameter (k) by fitting the negative binomial distribution in each phase. The frequencies of the secondary transmission were compared by demographic and clinical characteristics, calculating the odds ratio using logistic regression models. RESULTS: We observed that 76.7% of the primary cases did not generate secondary cases with an estimated dispersion parameter k of 0.23. The demographic patterns of primary-secondary cases differed between phases, with 20-69 years being the predominant age group. There were higher proportions of secondary transmissions among older individuals, symptomatic patients, and patients with 2 days or more between onset and confirmation. CONCLUSIONS: The study showed the estimation of the frequency of secondary transmission of SARS-CoV-2 and the characteristics of people who generated the secondary transmission.

  11. COVID-19 case-clusters and transmission chains in the communities in Japan International-journal Peer-reviewed

    Yuki Furuse, Naho Tsnchiya, Reiko Miyahara, Dckoh Yasuda, Eiichiro Sando, Yura K Ko, Takeaki Imamura, Konosiike Morimoto, Tadatsugu Imamura, Yugo Shobugawa, Shohei Nagata, Atsuna Tokiimoto, Kazuaki Jiiidai, Motoi Suzuki, Hitoshi Oshitani

    Journal of Infection　84　(2)　248-288　2021/08/11

    Publisher: Elsevier BV

    DOI： 10.1016/j.jinf.2021.08.016 　

    ISSN： 0163-4453

  12. Roles of Children and Adolescents in COVID-19 Transmission in the Community: A Retrospective Analysis of Nationwide Data in Japan International-journal Peer-reviewed

    Tadatsugu Imamura, Mayuko Saito, Yura K. Ko, Takeaki Imamura, Kanako Otani, Hiroki Akaba, Kota Ninomiya, Yuki Furuse, Reiko Miyahara, Eiichiro Sando, Ikkoh Yasuda, Naho Tsuchiya, Motoi Suzuki, Hitoshi Oshitani

    Frontiers in Pediatrics　9　705882-705882　2021/08/10

    Publisher: Frontiers Media SA

    DOI： 10.3389/fped.2021.705882 　

    eISSN： 2296-2360

    More details Close

    <bold>Background:</bold> Roles of children and adolescents in spreading coronavirus disease 2019 (COVID-19) in the community is not fully understood. <bold>Methods:</bold> We analyzed the data of 7,758 children and adolescents with COVID-19 and characteristics of secondary transmission generated by these cases using case information published by local governments. Ratio of pediatric and adolescent cases generating secondary transmission was calculated for various social settings. <bold>Results:</bold> The incidence of COVID-19 was 24.8 cases per 105 population aged between 0 and 9 years, and 59.2 among those aged between 10 and 19 years, which was lower than that among individuals of all age groups (79.6 per 105 population) between January 15 and October 31, 2020. The proportion of cases generating secondary cases was 8.3% among infants and young children in nursery schools and kindergartens, 16% among children and adolescents attending primary schools, 34% among those attending junior high schools, 43% among those attending high schools, 31% among those attending professional training colleges, and 24% in those attending universities. Households were the most common setting for secondary transmission. <bold>Conclusion:</bold> The risk of generating secondary cases might be limited among pediatric and adolescent cases with COVID-19, especially in settings outside households. Effectiveness of traditional mitigation measures (e.g., school closures) to suppress COVID-19 transmissions should be carefully evaluated.

  13. Familial Clusters of Coronavirus Disease in 10 Prefectures, Japan, February−May 2020 Peer-reviewed

    Reiko Miyahara, Naho Tsuchiya, Ikkoh Yasuda, Yura K. Ko, Yuki Furuse, Eiichiro S, o, Shohei Nagata, Tadatsugu Imamura, Mayuko Saito, Konosuke Morimoto, Takeaki Imamura, Yugo Shobugawa, Hiroshi Nishiura, Motoi Suzuki, Hitoshi Oshitani

    Emerging Infectious Diseases　27　(3)　915-918　2021/03

    Publisher: Centers for Disease Control and Prevention ({CDC})

    DOI： 10.3201/eid2703.203882 　

    ISSN： 1080-6040 1080-6059

  14. Influenza Advances in Diagnosis and Management

    Takeaki Imamura

    2020/11/11

    Publisher: Springer

  15. Clusters of Coronavirus Disease in Communities, Japan, January-April 2020. International-journal Peer-reviewed

    Yuki Furuse, Eiichiro Sando, Naho Tsuchiya, Reiko Miyahara, Ikkoh Yasuda, Yura K Ko, Mayuko Saito, Konosuke Morimoto, Takeaki Imamura, Yugo Shobugawa, Shohei Nagata, Kazuaki Jindai, Tadatsugu Imamura, Tomimasa Sunagawa, Motoi Suzuki, Hiroshi Nishiura, Hitoshi Oshitani

    Emerging infectious diseases　26　(9)　2176-9　2020/09

    DOI： 10.3201/eid2609.202272 　

    More details Close

    We analyzed 3,184 cases of coronavirus disease in Japan and identified 61 case-clusters in healthcare and other care facilities, restaurants and bars, workplaces, and music events. We also identified 22 probable primary case-patients for the clusters; most were 20-39 years of age and presymptomatic or asymptomatic at virus transmission.

  16. Neurogenic pulmonary edema following febrile status epilepticus in a 22-month-old infant with multiple respiratory virus co-detection: a case report. International-journal Peer-reviewed

    Yoshie Takagi, Takeaki Imamura, Shota Endo, Kenta Hayashi, Satoka Akiyama, Yoji Ikuta, Takahiro Kawaguchi, Tomoko Sumita, Tatsuo Katori, Masanori Hashino, Shinji Saito, Takato Odagiri, Kunihiro Oba, Makoto Kuroda, Tsutomu Kageyama

    BMC infectious diseases　20　(1)　388-388　2020/06/01

    Publisher: Springer Science and Business Media LLC

    DOI： 10.1186/s12879-020-05115-2 　

    eISSN： 1471-2334

    More details Close

    BACKGROUND: Neurogenic pulmonary edema is a rare but serious complication of febrile status epilepticus in children. Comprehensive screening for viral pathogens is seldomly performed in the work-up of febrile children. CASE PRESENTATION: A 22-month-old girl presented with her first episode of febrile status epilepticus, after which she developed acute pulmonary edema and respiratory failure. After the termination of seizure activity, the patient was intubated and managed on mechanical ventilation in the emergency room. The resolution of respiratory failure, as well as the neurological recovery, was achieved 9 h after admission, and the patient was discharged 6 days after admission without any complications. Molecular biological diagnostic methods identified the presence of human coronavirus HKU1, influenza C virus, and human parainfluenza virus 2 from the patient's nasopharyngeal specimens. CONCLUSIONS: Neurogenic pulmonary edema following febrile status epilepticus was suspected to be the etiology of our patient's acute pulmonary edema and respiratory failure. Timely seizure termination and rapid airway and respiratory intervention resulted in favorable outcomes of the patient. Molecular biological diagnostic methods identified three respiratory viruses; however, their relevance and association with clinical symptoms remain speculative.

  17. Potential underestimation of influenza virus burden in infants. International-journal Peer-reviewed

    Takeaki Imamura, Mayuko Saito, Hitoshi Oshitani

    The Lancet. Child & adolescent health　3　(11)　751-752　2019/11

    DOI： 10.1016/S2352-4642(19)30278-0 　

    ISSN： 2352-4642

  18. カルシウム拮抗薬の急性薬物中毒に対し塩化カルシウムの投与が奏功した1症例 Peer-reviewed

    野原 春菜, 有野 聡, 今村 剛朗, 松吉 健夫, 佐々木 庸郎, 山口 和将, 一瀬 麻紀, 小島 直樹, 稲川 博司, 岡田 保誠

    日本救急医学会関東地方会雑誌　39　(3)　366-369　2019/01

    Publisher: 日本救急医学会-関東地方会

    ISSN： 0287-301X

  19. 精神科病院を経由して当院救急外来を受診した53例の検討 Peer-reviewed

    岡田 保誠, 稲川 博司, 小島 直樹, 山口 和将, 佐々木 庸郎, 一瀬 麻紀, 有野 聡, 今村 剛朗, 松吉 健夫, 小山 知秀

    日本救急医学会雑誌　29　(10)　500-500　2018/10

    Publisher: (一社)日本救急医学会

    ISSN： 0915-924X

    eISSN： 1883-3772

  20. アンギオテンシンII受容体拮抗薬による血管性浮腫を呈した1例 Peer-reviewed

    渡辺隆明, 岡田保誠, 稲川博司, 小島直樹, 山口和将, 佐々木庸郎, 今村剛朗, 松吉健夫

    日本救急医学会関東地方会雑誌　37　(2)　442‐445　2016/12/25

    ISSN： 0287-301X

  21. pH6.784と著明なアシドーシスで来院したにもかかわらず救命し得た大酒家の1例 Peer-reviewed

    中澤太一, 渡邉隆明, 今村剛朗, 松吉健夫, 佐々木庸郎, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会関東地方会雑誌　37　(2)　511‐515　2016/12/25

    ISSN： 0287-301X

  22. Risk assessment of recent Egyptian H5N1 influenza viruses Peer-reviewed

    A. -S. Arafa, S. Yamada, M. Imai, T. Watanabe, S. Yamayoshi, K. Iwatsuki-Horimoto, M. Kiso, Y. Sakai-Tagawa, M. Ito, T. Imamura, N. Nakajima, K. Takahashi, D. Zhao, K. Oishi, A. Yasuhara, C. A. Macken, G. Zhong, A. P. Hanson, S. Fan, J. Ping, M. Hatta, T. J. S. Lopes, Y. Suzuki, M. El-Husseiny, A. Selim, N. Hagag, M. Soliman, G. Neumann, H. Hasegawa, Y. Kawaoka

    Scientific Reports　6　38388　2016/12

    DOI： 10.1038/srep38388 　

    ISSN： 2045-2322

  23. A case of acute myocardial infarction following intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke Peer-reviewed

    今村剛朗, 佐々木庸郎, 松吉健夫, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会雑誌　27　(1)　28‐34　2016/01/15

    ISSN： 0915-924X

  24. A case of acute myocardial infarction following intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke(急性期脳梗塞に対するrt–PA投与後に急性心筋梗塞を発症した1症例(A case of acute myocardial infarction following intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke

    佐々木 庸郎 (Nobuo Sasaki), 松吉 健夫 (Takeo Matsuyoshi), 山口 和将 (Kazumasa Yamaguchi), 小島 直樹 (Naoki Kojima), 稲川 博司 (Hiroshi Inagawa), 岡田 保誠 (Yasusei Okada)

    Nihon Kyukyu Igakukai Zasshi: Journal of Japanese Association for Acute Medicine　2016/01

    DOI： 10.1002/jja2.12080 　

    ISSN： 1883-3772

    More details Close

    <jats:title>要旨</jats:title><jats:p>急性期脳梗塞に対するアルテプラーゼ（rt–PA）静注療法は，一般的な治療になりつつある。今回我々は，rt–PA静注療法を契機に急性心筋梗塞を発症した症例を経験した。症例は，とくに既往症のない72歳の女性。急性発症の構音障害と左片麻痺を呈して救急搬送され，頭部MRIで右側頭葉内側に急性期脳梗塞を認めた。発症後2時間30分でrt–PA静注療法を施行したところ，投与終了後2時間でうっ血性心不全，低酸素による心原性ショックに陥った。冠動脈造影検査を施行し，左前下行枝（#6）の閉塞を認め，ステントによる経皮的冠動脈形成術を施行した。経過よりrt–PA静注療法を契機に急性心筋梗塞を発症したと考えた。急性期脳梗塞に対するrt–PA静注療法後には，急性心筋梗塞を発症する可能性がある。発症頻度や機序は不明であるが，症例報告が散見され注意を要する病態である。</jats:p>

  25. A case of streptococcal toxic shock-like syndrome presented as primary peritonitis Peer-reviewed

    松吉健夫, 今村剛朗, 佐々木庸郎, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本集中治療医学会雑誌(Web)　23　(1)　61‐62 (J‐STAGE)　2016

    DOI： 10.3918/jsicm.23.61 　

    ISSN： 1882-966X

  26. めまいの診察におけるピットフォール:当院救急外来における639症例の検討を踏まえて Peer-reviewed

    坂上達也, 小島直樹, 渡邉隆明, 澄田奏子, 松吉健夫, 今村剛朗, 佐々木庸郎, 山口和将, 稲川博司, 岡田保誠

    日本救急医学会関東地方会雑誌　36　(2)　206‐207　2015/12/25

    ISSN： 0287-301X

  27. マンパワーが限られた救命救急センターでいかに三次救急の質を担保しつつ二次救急を充実させるか Peer-reviewed

    小島直樹, 岡田保誠, 稲川博司, 山口和将, 佐々木庸郎, 松吉健夫, 今村剛朗, 渡邉隆明, 澄田奏子

    日本救急医学会関東地方会雑誌　36　(2)　232‐233　2015/12/25

    ISSN： 0287-301X

  28. 危険ドラッグ乱用により重度の横紋筋融解症,急性腎傷害を生じた1例 Peer-reviewed

    山口和将, 澄田奏子, 渡邉隆明, 今村剛朗, 松吉健夫, 佐々木庸郎, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会関東地方会雑誌　36　(2)　272‐274　2015/12/25

    ISSN： 0287-301X

  29. 致死的肺血栓塞栓症を来した外来ギプス治療中単独下肢外傷の2症例 Peer-reviewed

    佐々木庸郎, 今村剛朗, 松吉健夫, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会雑誌　26　(2/3)　79‐84　2015/03/15

    ISSN： 0915-924X

  30. 腹部内臓動脈瘤破裂による出血性ショックに対し、IABO挿入下にTAEを施行して救命しえた2例 Peer-reviewed

    人見 秀, 佐々木 庸郎, 渡邉 隆明, 澄田 奏子, 今村 剛朗, 松吉 健夫, 山口 和将, 小島 直樹, 稲川 博司, 岡田 保誠, 川合 豪, 白田 剛, 海野 俊之

    日本救急医学会関東地方会雑誌　36　(1)　137-137　2015/02

    Publisher: 日本救急医学会-関東地方会

    ISSN： 0287-301X

    eISSN： 2434-2580

  31. A case of fulminant amebic colitis associated with chemotherapy Peer-reviewed

    小島直樹, 今村剛朗, 松吉健夫, 佐々木庸郎, 山口和将, 稲川博司, 岡田保誠, 小田智三

    日本集中治療医学会雑誌(Web)　22　(3)　213-214 (J-STAGE)　2015

    DOI： 10.3918/jsicm.22.213 　

    ISSN： 1882-966X

  32. 高カリウム血症と高度な循環不全を呈した劇症1型糖尿病の1症例 Peer-reviewed

    松吉健夫, 渡邉隆明, 澄田奏子, 今村剛朗, 佐々木庸郎, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会関東地方会雑誌　35　(2)　249-252　2014/12/25

    ISSN： 0287-301X

  33. Pheochromocytoma crisis with acute heart failure and multiple organ failure Peer-reviewed

    松吉健夫, 今村剛朗, 佐々木庸郎, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会雑誌　25　(7)　313-318 (J-STAGE)-318　2014

    Publisher: Japanese Association for Acute Medicine

    DOI： 10.3893/jjaam.25.313 　

    ISSN： 0915-924X

    More details Close

    A 34-year-old woman with abdominal pain experienced hypoxemia during clinical examination and was intubated. Abdominal contrast-enhanced computed tomography revealed huge bilateral adrenal tumors, necessitating transfer to our hospital. At admission, she had persistent hypertension and tachycardia. Laboratory data revealed liver and kidney impairment, and marked increase in catecholamine level. She was treated with an alpha-blocker and other antihypertensive drugs. On day 3, pulmonary edema resolved and liver function improved. Kidney impairment worsened, and hemodialysis was required three times until day 9; however, subsequently, kidney function improved. The patient was extubated on day 8, and her condition stabilized after administration of several antihypertensive drugs. Then, she was operated and diagnosed with multiple endocrine neoplasia type 2A. Pheochromocytoma is difficult to diagnose and should be considered during differential diagnosis. In the present case, several antihypertensive drugs were required not only during the acute phase but also after stabilization, indicating that these tumors produce enormous amounts of catecholamine continually. Although the timing of surgery is controversial in a pheochromocytoma crisis, our patient recovered from multiple organ failure by intensive medical care and received definitive therapy during the stabilized period.

  34. 感染症 ペット溺愛者に生じたCapnocytophaga canimorsusによる敗血症性ショックの1症例 Peer-reviewed

    今村剛朗, 松吉健夫, 広瀬由和, 澄田奏子, 渡邊隆明, 山口和将, 小島直樹, 稲川博司, 岡田保誠, 小田智三

    日本救急医学会関東地方会雑誌　34　(2)　239-242　2013/12/25

    ISSN： 0287-301X

  35. 代謝・内分泌他 Systemic Capillary Leak Syndrome様の臨床像を呈し,診断に苦慮したNK/T Cell Lymphomaの1例 Peer-reviewed

    渡辺隆明, 澄田奏子, 今村剛朗, 広瀬由和, 松吉健夫, 小島直樹, 稲川博司, 岡田保誠, 藤田彰, 張京浩, 小山知秀

    日本救急医学会関東地方会雑誌　34　(2)　298-300　2013/12/25

    ISSN： 0287-301X

  36. 塩化第二水銀の大量服用による急性中毒の1症例 Peer-reviewed

    今村剛朗, 松吉健夫, 広瀬由和, 山地晶子, 澄田奏子, 渡邊隆明, 佐々木庸郎, 小山知秀, 山口和将, 小島直樹, 稲川博司, 岡田保誠, 小野真吾, 武田雄一, 野内俊彦

    日本救急医学会関東地方会雑誌　33　168-170　2012/12/25

    ISSN： 0287-301X

  37. ウブレチド内服中の高齢者の呼吸不全の鑑別にはコリン作動性クリーゼを忘れるな Peer-reviewed

    渡辺隆明, 澄田奏子, 今村剛朗, 広瀬由和, 松吉健夫, 山地晶子, 佐々木庸郎, 小山知秀, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会関東地方会雑誌　33　181-182　2012/12/25

    ISSN： 0287-301X

  38. ガソリンを飲んだ後化学性肺炎を起こし非侵襲的陽圧換気の導入により改善を認めた1症例 Peer-reviewed

    広瀬由和, 澄田奏子, 渡邊隆明, 今村剛朗, 松吉健夫, 山地晶子, 佐々木庸郎, 小山知秀, 山口和将, 小島直樹, 稲川博司, 岡田保誠, 張京浩

    日本救急医学会関東地方会雑誌　33　173-175　2012/12/25

    ISSN： 0287-301X

  39. ステロイドパルス療法が有効であった重症レジオネラ肺炎の1症例 Peer-reviewed

    松吉健夫, 渡邊隆明, 澄田奏子, 今村剛朗, 広瀬由和, 山地晶子, 佐々木庸郎, 小山知秀, 山口和将, 小島直樹, 稲川博司, 岡田保誠

    日本救急医学会関東地方会雑誌　33　142-143　2012/12/25

    ISSN： 0287-301X

  40. 緊急輪状甲状間膜切開術を要した急性喉頭蓋炎でNegative Pressure Pulmonary Edemaを来たした1症例 Peer-reviewed

    今村剛朗, 小島直樹, 津嘉山博行, 西村祥一, 佐々木庸郎, 山口和将, 古谷良輔, 稲川博司, 岡田保誠, 遠藤麻世, 小泉めぐみ, 北原伸郎

    日本救急医学会関東地方会雑誌　31　92-93　2010/12/25

    ISSN： 0287-301X

Show all ︎Show first 5

Misc. 8

  1. 産褥期にPRES(posteror reeversible encephalopathy syndrome)を呈した4症例

    山口 和将, 澄田 奏子, 渡邉 隆明, 今村 剛朗, 広瀬 由和, 松吉 健夫, 佐々木 庸郎, 小島 直樹, 稲川 博司, 岡田 保誠, 小山 知秀

    日本救急医学会雑誌　24　(8)　653-653　2013/08

    Publisher: (一社)日本救急医学会

    ISSN： 0915-924X

  2. 心肺機能停止蘇生後の治療的低体温療法導入症例における早発性肺炎に関する検討

    山口 和将, 澄田 奏子, 渡辺 隆明, 今村 剛朗, 広瀬 由和, 松吉 健夫, 小島 直樹, 稲川 博司, 岡田 保誠, 張 京浩, 小山 知秀

    日本救急医学会雑誌　23　(10)　695-695　2012/10

    Publisher: (一社)日本救急医学会

    ISSN： 0915-924X

  3. 血管性浮腫が疑診の段階でC1-INH製剤(ベリナートR)は投与するべきか?

    小島 直樹, 渡辺 隆明, 澄田 奏子, 広瀬 由和, 今村 剛朗, 松吉 健夫, 小山 知秀, 山口 和将, 稲川 博司, 岡田 保誠

    日本臨床救急医学会雑誌　15　(2)　293-293　2012/04

    Publisher: (一社)日本臨床救急医学会

    ISSN： 1345-0581

  4. Distigmine Bromide(ウブレチド)少量の内服でコリン作動性クリーゼに陥った一症例

    山地 晶子, 今村 剛朗, 広瀬 由和, 松吉 健夫, 佐々木 庸郎, 小山 知秀, 山口 和将, 小島 直樹, 稲川 博司, 岡田 保誠

    日本集中治療医学会雑誌　19　(Suppl.)　251-251　2012/01

    Publisher: (一社)日本集中治療医学会

    ISSN： 1340-7988

  5. 意識障害で救急搬送されまれな内分泌疾患であることが判明した2症例

    今村 剛朗, 佐々木 庸郎, 小山 知秀, 山口 和将, 小島 直樹, 稲川 博司, 岡田 保誠, 内潟 雅信, 三谷 康二, 重田 真幸

    日本集中治療医学会雑誌　19　(Suppl.)　278-278　2012/01

    Publisher: (一社)日本集中治療医学会

    ISSN： 1340-7988

  6. くも膜下出血の責任病変部位と神経原性肺水腫の発症頻度の関係

    山口 和将, 岡田 保誠, 渡邉 隆明, 澄田 奏子, 今村 剛朗, 松吉 健夫, 広瀬 由和, 佐々木 庸郎, 小山 知秀, 小島 直樹, 稲川 博司

    日本救急医学会雑誌　22　(8)　528-528　2011/08

    Publisher: (一社)日本救急医学会

    ISSN： 0915-924X

  7. A型インフルエンザウィルス感染による横紋筋融解症によって急性腎傷害を生じた高齢者の1例

    松吉 健夫, 今村 剛朗, 広瀬 由和, 山地 晶子, 佐々木 庸郎, 小山 知秀, 山口 和将, 小島 直樹, 稲川 博司, 岡田 保誠, 津嘉山 博行

    日本救急医学会雑誌　22　(8)　672-672　2011/08

    Publisher: (一社)日本救急医学会

    ISSN： 0915-924X

  8. 肺炎球菌抗原迅速検出キットを用いた髄液中抗原の検出が髄膜炎診断に有用であった1症例

    広瀬 由和, 今村 剛朗, 津嘉山 博行, 佐々木 庸郎, 小山 知秀, 山口 和将, 小島 直樹, 稲川 博司, 岡田 保誠, 松吉 健夫, 佐々木 裕子

    日本臨床救急医学会雑誌　14　(2)　362-362　2011/04

    Publisher: (一社)日本臨床救急医学会

    ISSN： 1345-0581

Show all ︎Show first 5

Books and Other Publications 3

  1. 新型コロナウイルスと闘う最前線

    今村剛朗, 仁宮洸太, 押谷仁

    BIO Clinica　2022/11/10

  2. Influenza Advances in Diagnosis and Management

    Takeaki Imamura, Hitoshi Oshitani

    Springer　2020/11

  3. 分子細胞免疫学

    Abbas, Abul K., Lichtman, Andrew H., 松島, 綱治, 山田, 幸宏

    エルゼビア・ジャパン　2008/07

    ISBN: 9784860348717

Presentations 4

  1. ザンビア共和国のCOVID-19入院症例に施行された酸素療法に関する診療録振返り研究

    今村剛朗, Suilanji Sivile, 今村忠嗣, 佐々木庸郎, 稲葉昌道, Paul Msanzya Zulu, Lloyd Mulenga

    第52回日本集中治療医学会学術集会　2025/03/14

  2. Limited oxygen therapy capacity against COVID-19 and the public health response in Zambia 2021

    Suilanji Sivile, Takeaki Imamura, Tadatsugu Imamura, Paul M. Zulu, Masuzyo Zyambo, Papytcho Ntambwe, Ndaba. Spuka, Julien Chomba, Anita Enane, O-TIPO Sikanga, Alphonsina Hamalala, Hamuganyu Innocen, Christopher Chanda, Loyd, B. Mulenga

    IDWeek2024　2024/10/17

  3. Limited oxygen therapy capacity against COVID-19 and the public health response in Zambia 2021

    Takeaki Imamura, Sivile Suilanji, Tadatsugu Imamura, Zulu Pual, Zyambo Masuzyo, Ntambwe Papytcho, Spuka Ndaba, Chomba Julien, Enane Anita, Sikanga OTIPO, Hamalala Alphonsina, Innocent Hamuganyu, Chanda Christopher, Mulenga Lloyd

    2024/08/03

  4. ヨルダン川西岸地区における現状と国境なき医師団による医療援助活動‒ 救急医の視点から‒

    今村剛朗

    日本外傷学会総会　2024/04/26

Research Projects 4

  1. 疫学・病原体ゲノム・人流データの融合によるCOVID-19感染拡大様式の解明

    今村 剛朗

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 基盤研究(B)

    Institution: 東北大学

    2025/04/01 - 2028/03/31

  2. Comprehensive analysis of causative pathogens among septic patients in Republic of Zambia

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists

    Category: Grant-in-Aid for Early-Career Scientists

    Institution: Tohoku University

    2020/04/01 - 2023/03/31

  3. Immunological impact of factors in breast milk on norovirus infection among infants

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))

    Category: Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))

    Institution: Tohoku University

    2019/10/07 - 2022/03/31

  4. フィリピン小児出生コホートにおける急性呼吸器感染症病原体の経時的かつ網羅的解析

    今村 剛朗

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業 研究活動スタート支援

    Category: 研究活動スタート支援

    Institution: 東北大学

    2019/08/30 - 2022/03/31

    More details Close

    急性呼吸器感染症は小児において重要な疾患であり、発展途上国では小児死亡の主原因でもある。急性呼吸器感染症に関与する病原体の解明は、小児急性呼吸器感染症の診断や治療、予防に重要である。フィリピンの小児出生コホートにおける定期的な呼吸器検体採取と分子生物学的検出手法の併用により、小児急性呼吸器感染症に関与する病原体の経時的かつ網羅的解析を目的として本研究を行うこととした。 <BR> 本研究開始に向けて、フィリピンの熱帯医学研究所を始めとするフィリピン共和国研究協力機関と協議を行ない、フィリピン共和国ビリラン島にある研究協力病院と地域保健施設の現地視察などを行なっていた。しかし、2019年12月に検出された新型コロナウイルス(SARS-CoV-2)によるパンデミックのため、フィリピン共和国は長期間のロックダウンを行なっていて、渡航や新規研究活動の開始は困難であり、研究活動の再開の見込みは立っていない。 <BR> 新規の出生コホート研究開始に代えて、既存検体を用いた小児急性呼吸器感染症に関与する病原体の網羅的解析を進めている。当研究室には、以前にフィリピン共和国で実施した小児急性呼吸器感染症に関する研究で収集した上気道検体が保管されている。それらの検体を用いて、ウイルスと細菌を主たる標的とした小児急性呼吸器感染症に関与する病原体の網羅的解析を行う予定である。現在、解析対象検体の選定を実施中である。