Details of the Researcher

PHOTO

Takashi Kamei
Section
Tohoku University Hospital
Job title
Professor
Degree

Education 2

  • Tohoku University　Graduate School, Division of Medical Sciences

    - 1999/03

  • Tohoku University　Faculty of Medicine

    - 1991/03/31

Committee Memberships 2

  • 日本食道学会　評議員

    2003/04 - Present

  • 日本食道学会　評議員

    2003/04 - Present

Professional Memberships 12

  • 宮城周術期管理研究会(2010/04- 世話人)

  • 食道内視鏡外科研究会(2010/07- 世話人)

  • 日本臨床外科学会(2010/12-)

  • International Society of Disease of the Esophagus(2008/03-)

  • 日本静脈経腸栄養学会(2007/12-)

  • 日本癌治療学会(2004/11-)

  • 日本腹部救急医学会(2000/10-)

  • 日本胸部外科学会(2007/10-)

  • 日本内視鏡外科学会(2001/04-)

  • 日本消化器外科学会(1991/10-)

  • 日本外科学会(1991/10-)

  • 日本食道学会(2003/04- 評議員)

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Research Areas 1

  • Life sciences / Digestive surgery / 食道・胃外科

Papers 36

  1. Combination of longitudinal pancreaticojejunostomy with coring-out of the pancreatic head (Frey procedure) and distal pancreatectomy for chronic pancreatitis. Peer-reviewed

    Hideaki Sato, Masaharu Ishida, Fuyuhiko Motoi, Naoaki Sakata, Takeshi Aoki, Hideyuki Suzuki, Akihiro Yamamura, Hideaki Karasawa, Tatsuo Hata, Hideo Ohtsuka, Masamichi Mizuma, Takanori Morikawa, Hiroki Hayashi, Kei Nakagawa, Takashi Kamei, Takeshi Naitoh, Shinichi Egawa, Michiaki Unno

    Surgery today　49　(2)　137-142　2019/02

    DOI： 10.1007/s00595-018-1720-1 　

    ISSN： 0941-1291

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    PURPOSE: The Frey procedure is an effective surgery for chronic pancreatitis (CP) patients who have pancreatic head lesions with dilation of the main pancreatic duct. However, pancreatic tail lesions can cause relapsing pancreatitis after the procedure. Therefore, additional distal pancreatectomy (DP) might complement the therapeutic effect of the Frey procedure in controlling inflammation of the pancreatic tail. The Frey procedure with DP (Frey + DP) is indicated for inflammatory lesions in the pancreatic head and tail. In this study, we assessed the usefulness of Frey + DP using the retrospective clinical data of our cases. METHODS: The clinical outcomes were compared between CP patients who underwent the Frey procedure (N = 44) and Frey + DP (N = 13) from January 2005 to April 2016. RESULTS: Frey + DP showed similarly good therapeutic effects to the Frey procedure with regard to the postoperative stay, morbidity, mortality, pain relief and nutrition, although the Frey + DP had a longer operative time, more bleeding and higher incidence of diabetes mellitus than the Frey procedure because of the additional DP. One patient in the Frey group received additional DP because of recurrent pain due to the tail lesion. CONCLUSION: Frey + DP can be a promising treatment for CP patients with pancreatic head and tail lesions.

  2. Lymph nodes around the posterior gastric artery: their existence, frequency, and clinical implications. Peer-reviewed

    Kentaro Ishii, Masaharu Ishida, Norihiko Sugisawa, Megumi Murakami, Tomoyuki Ono, Tomoyoshi Tachibana, Hirofumi Imoto, Takeshi Aoki, Katsuyoshi Kudoh, Shinobu Ohnuma, Naoaki Sakata, Hiroaki Musha, Takanori Morikawa, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno

    Surgery today　48　(10)　916-920　2018/10

    DOI： 10.1007/s00595-018-1677-0 　

    ISSN： 0941-1291

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    PURPOSE: The lymphatic flow along the posterior gastric artery (PGA) is considered of possible clinical importance in terms of lymphatic metastasis; however, little is known about the lymph nodes (LNs) around this artery. The purpose of this study was to establish if LNs exist around the PGA and to evaluate their clinical implications. METHODS: We examined the tissues surrounding the PGA from 21 cadavers to search for LNs. We also investigated the patterns of lymphatic metastases in patients who underwent surgery for gastric neoplasms at our institute to detect their presence along the PGA. RESULTS: The PGA was identified in 11 cadavers, and LNs around the PGA were detected microscopically in 2 of these. Lymphatic metastasis directly to the LNs at the splenic artery without any metastases was regarded as skip metastasis along the PGA. Skip metastasis was found in two of ten patients who underwent surgery for remnant gastric cancer. CONCLUSIONS: The existence of LNs around the PGA was confirmed, and based on our findings, lymphatic metastasis through the PGA is possible in patients with remnant gastric cancer.

  3. Myosin 5a regulates tumor migration and epithelial-mesenchymal transition in esophageal squamous cell carcinoma: utility as a prognostic factor. International-journal Peer-reviewed

    Naomi Sato, Fumiyoshi Fujishima, Yasuhiro Nakamura, Yayoi Aoyama, Yoshiaki Onodera, Yohei Ozawa, Ken Ito, Hirotaka Ishida, Takashi Kamei, Mika Watanabe, Hironobu Sasano

    Human pathology　80　113-122　2018/10

    DOI： 10.1016/j.humpath.2018.06.002 　

    ISSN： 0046-8177

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    Esophageal squamous cell carcinoma (ESCC) is highly malignant. Recently, the expression of myosin 5a, a member of the myosin superfamily, was reported to be associated with increased invasiveness and metastasis in many tumor types. Moreover, myosin 5a is upregulated by Snail and activated by Akt2, both of which are epithelial-mesenchymal transition (EMT) markers. In this study, we confirmed the expression of myosin 5a in ESCC surgical specimens and cell lines, revealing its correlation with tumor invasion, migration, patient prognosis, and expression of EMT-related proteins. The expression of myosin 5a, vimentin, and E-cadherin was immunohistochemically evaluated in 118 patients with ESCC who underwent esophagectomy without chemotherapy or irradiation therapy prior to surgery. We also investigated ESCC cell migration under myosin 5a silencing by siRNA induction. The high expression of myosin 5a was correlated with tumor depth, lymph node metastasis, pathological stage, high vimentin expression, and low E-cadherin expression. Patients with high expression of myosin 5a, including those with pT1 cancer, exhibited significantly worse survival. Moreover, the expression level of vimentin mRNA and the number of migrated ESCC cells decreased significantly following myosin 5a silencing. Our findings demonstrate that high expression of myosin 5a may be an independent prognostic factor in patients with ESCC, even in early invasive carcinoma, and indicate myosin 5a has a role in both cell migration and EMT.

  4. Definitive chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-R) for advanced cervical esophageal cancer. Peer-reviewed

    Okamoto H, Taniyama Y, Sakurai T, Heishi T, Teshima J, Sato C, Maruyama S, Ito K, Onodera Y, Konno-Kumagai T, Ishida H, Kamei T

    Esophagus : official journal of the Japan Esophageal Society　15　(4)　281-285　2018/10

    DOI： 10.1007/s10388-018-0627-7 　

    ISSN： 1612-9059

  5. Surgical strategy for an adult patient with a catecholamine-producing ganglioneuroblastoma and a cerebral aneurysm: a case report. International-journal Peer-reviewed

    Kumata H, Nishimura R, Nakanishi C, Inoue C, Tezuka Y, Endo H, Miyagi S, Tominaga T, Unno M, Kamei T

    Surgical case reports　4　(1)　119-119　2018/09

    DOI： 10.1186/s40792-018-0529-x 　

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    BACKGROUND: Ganglioneuroblastomas, particularly those that produce catecholamine, are extremely rare in adults. Here, we report an interesting surgical case of an adult patient with a catecholamine-producing ganglioneuroblastomas in her adrenal gland, suspected to be a pheochromocytoma, and with a cerebral aneurysm. CASE PRESENTATION: The patient was a 73-year-old woman under treatment for hypertension. During a health check-up, a cystic retroperitoneal tumor was incidentally found in the superior pole of her right kidney. Her blood adrenaline level was slightly elevated, and her urinary adrenaline, noradrenaline, and dopamine levels were above the upper reference limits. In addition, 24-h urinary excretion of metanephrine, normetanephrine, and vanillylmandelic acid were all increased. 123I-Meta-iodobenzylguanidine scintigraphy showed an abnormal accumulation of the marker in the cyst wall. She was, therefore, diagnosed with a pheochromocytoma and scheduled for tumor resection. However, preoperatively, 8-mm-diameter cerebral aneurysm was incidentally found in her basilar artery. This required careful preoperative discussion. The aneurysm was difficult to approach and treat, and based on its position, shape, and size, the risk of rupture was low. Because hypertension is a major risk factor for aneurysmal rupture, we decided to proceed with the tumor resection. A lumbar catheter was placed to monitor the cerebral aneurysm for intraoperative rupture, and her transcranial motor-evoked potential and somatosensory-evoked potentials were monitored to track her intraoperative neurological function. During surgery, we carefully monitored fluctuations in blood pressure and resected the tumor with minimal mobilization. Postoperatively, head computed tomography confirmed that there was no sign of rupture. Histopathologically, the tumor was diagnosed as a catecholamine-producing ganglioneuroblastoma. The postoperative course was good, and the patient's blood pressure improved. CONCLUSIONS: Careful perioperative management is needed for a patient with both a catecholamine-producing tumor and cerebral aneurysm.

  6. Hiatal hernia involving prolapse of the entire stomach into the mediastinum after distal gastrectomy: a case report. International-journal Peer-reviewed

    Konno-Kumagai T, Takeyama D, Nakano T, Sakurai T, Taniyama Y, Heishi T, Sato C, Kamei T

    Surgical case reports　4　(1)　93-93　2018/08

    DOI： 10.1186/s40792-018-0503-7 　

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    BACKGROUND: Prolapse of a small part of the proximal stomach through the hiatus into the mediastinum is relatively common. Hiatal hernia involving the postoperative stomach has been reported previously, but the degree of hernia was not so severe, and hiatal hernia involving the prolapse of the entire stomach following gastrectomy into the mediastinum has never been reported. We describe a very rare case of large hiatal hernia involving the entire postoperative stomach. CASE PRESENTATION: A 79-year-old man with a history of distal gastrectomy for submucosal benign tumor 40 years ago was referred to our hospital because of dysphagia and weight loss. Computed tomography revealed prolapse of the entire postoperative stomach into the mediastinum, and a radical operation was performed. There was a strong adhesion in the hernial sac of the mediastinum, but only little adhesion due to a previous open surgery in the abdominal cavity was present. After the stomach was pulled into the abdominal cavity, suture cruroplasty and Toupet fundoplication without dissection of the short gastric artery were performed. The patient experienced postoperative paralytic ileus, but the rest of the postoperative course was uneventful and the symptom of dysphagia improved. CONCLUSIONS: We presented a very rare large hiatal hernia involving the entire postoperative stomach. Toupet fundoplication preserving the short gastric artery could be one of the optimal surgeries to prevent postoperative regurgitation of the remnant stomach.

  7. Classical Hodgkin lymphoma-type and monomorphic-type post-transplant lymphoproliferative disorder following liver transplantation: a case report. International-journal Peer-reviewed

    Kumata H, Nakanishi C, Murakami K, Miyagi S, Fukuhara N, Carreras J, Nakamura N, Ichinohasama R, Unno M, Kamei T, Sasano H

    Surgical case reports　4　(1)　72-72　2018/07

    DOI： 10.1186/s40792-018-0480-x 　

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    BACKGROUND: Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication that can be difficult to treat; moreover, determination of the pathophysiological type is difficult. We report a rare case of a patient who developed two types of Epstein-Barr virus (EBV)-negative PTLD following living donor liver transplantation (LDLT). CASE PRESENTATION: A 64-year-old man underwent LDLT for acute fulminant hepatitis B. Sixty-five months later, he developed EBV-negative monomorphic B cell PTLD. Reduction of immunosuppressive therapy and chemotherapy with rituximab resulted in a partial response. He received radioimmunotherapy with yttrium-90-ibritumomab tiuxetan, which was effective for all lesions, except for the splenic hilar lesion, which enlarged and seemed to penetrate the stomach. Therefore, he underwent resection of the pancreatic tail with splenectomy and partial gastrectomy. The pathological diagnosis was EBV-negative classical Hodgkin lymphoma (cHL)-type PTLD. CONCLUSIONS: This patient showed an unexpected course of PTLD, from both a clinical and pathological perspective. There are no prior reports of an adult case of EBV-negative cHL-type PTLD coexisting with EBV-negative monomorphic B cell PTLD. When a strange and refractory lesion persists despite effective therapy for PTLD, we must consider the possibility of another type of PTLD within the residual lesion.

  8. Steroidogenesis in ovarian-like mesenchymal stroma of hepatic and pancreatic mucinous cystic neoplasms. International-journal Peer-reviewed

    Kumata H, Murakami K, Ishida K, Miyagi S, Arakawa A, Inayama Y, Kinowaki K, Ochiai A, Kojima M, Higashi M, Moritani S, Kuwahara K, Nakatani Y, Kajiura D, Tamura G, Kijima H, Yamakawa M, Shiraishi T, Inadome Y, Murakami K, Suzuki H, Sawai T, Unno M, Kamei T, Sasano H

    Hepatology research : the official journal of the Japan Society of Hepatology　48　(12)　989-999　2018/06

    DOI： 10.1111/hepr.13201 　

    ISSN： 1386-6346

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    STEROIDOGENESIS IN HEPATIC MUCINOUS CYSTIC NEOPLASM: Aim Mucinous cystic neoplasms (MCNs) occur in the ovary, pancreas, and retroperitoneum but very rarely in the liver. Mucinous cystic neoplasms are known to harbor ovarian-like mesenchymal stroma (OLS) expressing progesterone and estrogen receptors. In this study we evaluated steroidogenesis in OLS of 25 hepatic MCNs and 24 pancreatic MCNs. Methods Both steroid receptors and steroidogenic factors were immunohistochemically evaluated using H-scores and results were compared with those in 15 ovarian MCNs and 10 normal ovaries. Results Androgen receptor (AR) H-scores in OLS were significantly higher in hepatic, pancreatic, and ovarian MCN than those in normal ovaries. H-scores of cytochrome P450 17α-hydroxylase/c17-20 lyase (P450c17) and 5α-reductase-1 (5αRED-1) in the stroma were significantly higher in OLS of hepatic and pancreatic MCN than in the stroma of ovarian MCN and normal ovary. In tumor epithelium, AR H-scores were significantly higher in hepatic and pancreatic MCN than in ovarian MCN. In both hepatic and pancreatic MCN, a significant positive correlation was detected between AR H-score in the epithelium and P450c17 H-score in OLS (hepatic MCN: Pearson's r = 0.446, P = 0.025; pancreatic MCN: r = 0.432, P = 0.035). In pancreatic MCN, a significantly positive correlation was detected between AR H-score in the tumor epithelium and 5αRED-1 H-score in OLS (Pearson's r = 0.458, P = 0.024). Conclusions These results indicated that locally produced androgens in OLS could be pivotal for tumorigenesis of both hepatic and pancreatic MCN and influence epithelial cells, possibly in a paracrine fashion, which could represent biological significance of OLS in these neoplasms.

  9. Association of post-transplant donor-specific HLA antibody with liver graft fibrosis during long-term follow-up after pediatric liver transplantation Peer-reviewed

    Kazuaki Tokodai, Shigehito Miyagi, Chikashi Nakanishi, Yasuyuki Hara, Wataru Nakanishi, Koji Miyazawa, Kenji Shimizu, Keigo Murakami, Hironobu Sasano, Masafumi Goto, Michiaki Unno, Takashi Kamei

    Pediatric Transplantation　22　(3)　e13169　2018/05/01

    Publisher: Blackwell Publishing Inc.

    DOI： 10.1111/petr.13169 　

    ISSN： 1399-3046 1397-3142

  10. The effects of short-term subnormothermic perfusion after cold preservation on liver grafts from donors after circulatory death: An ex vivo rat model Peer-reviewed

    Yuta Kakizaki, Shigehito Miyagi, Kenji Shimizu, Koji Miyazawa, Wataru Nakanishi, Kazuaki Tokodai, Yasuyuki Hara, Chikashi Nakanishi, Michiaki Unno, Takashi Kamei, Masafumi Goto, Susumu Satomi

    Transplantation　102　(4)　e147-e154　2018/04/01

    Publisher: Lippincott Williams and Wilkins

    DOI： 10.1097/TP.0000000000002080 　

    ISSN： 0041-1337

  11. Treatment of spontaneous esophageal rupture (Boerhaave syndrome) using thoracoscopic surgery and sivelestat sodium hydrate Peer-reviewed

    Hiroshi Okamoto, Ko Onodera, Rikiya Kamba, Yusuke Taniyama, Tadashi Sakurai, Takahiro Heishi, Jin Teshima, Makoto Hikage, Chiaki Sato, Shota Maruyama, Yu Onodera, Hirotaka Ishida, Takashi Kamei

    Journal of Thoracic Disease　10　(4)　2206-2212　2018/04/01

    Publisher: AME Publishing Company

    DOI： 10.21037/jtd.2018.03.136 　

    ISSN： 2077-6624 2072-1439

  12. [Endoscopy-Assisted Partial Duodenal Resection for Duodenal Adenoma in a Patient with Familial Adenomatous Polyposis]. Peer-reviewed

    Tomoaki Hirashima, Shinobu Ohnuma, Hideaki Karasawa, Kazuhiro Watanabe, Hirofumi Imoto, Takeshi Aoki, Katsuyoshi Kudoh, Naoki Tanaka, Munenori Nagao, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno

    Gan to kagaku ryoho. Cancer & chemotherapy　45　(3)　518-520　2018/03

    ISSN： 0385-0684

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    We here report a case of endoscopy-assisted partial duodenal resection for duodenal adenoma in a patient with familial adenomatous polyposis(FAP). A male underwent total proctocolectomy with ileal pouch anal anastomosis in 1997. Since 2004, duodenal adenomas occurred and the atypical grade of adenoma was gradually aggravated. Therefore, he underwent endoscopy-assisted partial duodenal resection in 2013. The pathological finding of the specimen showed well-differentiated tubular adenocarcinoma(pM, ly0, v0). No recurrence has been observed at 4 years after the operation. Endoscopy-assisted partial duodenal resection was minimum invasive surgery and considered to be useful for the patients with duodenal adenoma.

  13. Different strategy of salvage esophagectomy between residual and recurrent esophageal cancer after definitive chemoradiotherapy Peer-reviewed

    Yusuke Taniyama, Tadashi Sakurai, Takahiro Heishi, Hiroshi Okamoto, Chiaki Sato, Shota Maruyama, Yu Onodera, Hirotaka Ishida, Michiaki Unno, Takashi Kamei

    Journal of Thoracic Disease　10　(3)　1554-1562　2018/03/01

    Publisher: AME Publishing Company

    DOI： 10.21037/jtd.2018.03.04 　

    ISSN： 2077-6624 2072-1439

  14. Thoracoscopic primary repair with mediastinal drainage is a viable option for patients with Boerhaave's syndrome Peer-reviewed

    Toru Nakano, Ko Onodera, Hirofumi Ichikawa, Takashi Kamei, Yusuke Taniyama, Tadashi Sakurai, Go Miyata

    Journal of Thoracic Disease　10　(2)　784-789　2018/02/01

    Publisher: AME Publishing Company

    DOI： 10.21037/jtd.2018.01.50 　

    ISSN： 2077-6624 2072-1439

  15. Curative resection of advanced esophageal cancer with metachronous stage IV breast cancer: A case report Peer-reviewed

    Yusuke Gokon, Tadashi Sakurai, Fumiyoshi Fujishima, Yusuke Taniyama, Takahiro Heishi, Hiroshi Okamoto, Shota Maruyama, Hirotaka Ishida, Yu Onodera, Hironobu Sasano, Takashi Kamei

    International Journal of Surgery Case Reports　45　133-137　2018/01/01

    Publisher: Elsevier Ltd

    DOI： 10.1016/j.ijscr.2018.03.022 　

    ISSN： 2210-2612

  16. A long-term survival case treated with conversion surgery following chemotherapy after diagnostic metastasectomy for pancreatic cancer with synchronous liver metastasis. International-journal Peer-reviewed

    Mitsuhiro Shimura, Masamichi Mizuma, Hiroki Hayashi, Akiko Mori, Tomoyoshi Tachibana, Tatsuo Hata, Masahiro Iseki, Tatsuyuki Takadate, Kyohei Ariake, Shimpei Maeda, Hideo Ohtsuka, Naoaki Sakata, Takanori Morikawa, Kei Nakagawa, Takeshi Naitoh, Takashi Kamei, Fuyuhiko Motoi, Michiaki Unno

    Surgical case reports　3　(1)　132-132　2017/12/29

    DOI： 10.1186/s40792-017-0409-9 　

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    BACKGROUND: Pancreatic cancer with distant metastases is classified as "unresectable," for which the standard treatment is systemic chemotherapy. The effectiveness of radical resection for pancreatic cancer with distant metastases is unknown. Here, we report a case of long term survival treated with conversion surgery following chemotherapy after diagnostic metastasectomy for pancreatic cancer with synchronous liver metastasis. CASE PRESENTATION: A 73-year-old man was referred to our hospital to examine and treat for cancer of the pancreatic body. Computed tomography (CT) scan revealed a 26-mm hypovascular tumor in contact with the common hepatic artery (CHA) (> 180°), the celiac artery (< 180°), and portal vein at the pancreatic body. Resectability was determined as "borderline resectable." Two courses of gemcitabine plus S-1 combination therapy (GS) were administered as neoadjuvant chemotherapy (NAC). CT scan showed tumor shrinkage (21 mm), determined as stable disease (SD) according to Response Evaluation Criteria in Solid Tumors (RECIST). Although the abdomen was opened for radical resection, a small nodule on the liver was detected and removed. Since the nodule was diagnosed as adenocarcinoma by intraoperative frozen section, resection of the primary tumor was not performed. After three subsequent courses of GS therapy, no distant metastases were detected under radiological findings. Distal pancreatectomy with celiac artery resection (DP-CAR) was performed as radical surgery 6 months after the initial diagnosis. Histological diagnosis was well-differentiated tubular adenocarcinoma, showing ypT1 ypN1 M1 stage IV, negative surgical margin (R0), and grade III in the Evans classification. S-1 was administered every other day from 6 months after resection up to the present. The patient has been alive with no recurrence for 5 years after the initial diagnosis and 4.5 years after the resection. CONCLUSION: There is a case that received survival benefits from conversion surgery following chemotherapy after diagnostic metastasectomy in pancreatic cancer with synchronous liver metastasis.

  17. Combined thoracoscopic and endoscopic surgery for a large esophageal schwannoma Peer-reviewed

    Yu Onodera, Toru Nakano, Daisuke Takeyama, Shota Maruyama, Yusuke Taniyama, Tadashi Sakurai, Takahiro Heishi, Chiaki Sato, Takuro Kumagai, Takashi Kamei

    WORLD JOURNAL OF GASTROENTEROLOGY　23　(46)　8256-8260　2017/12

    DOI： 10.3748/wjg.v23.i46.8256 　

    ISSN： 1007-9327

    eISSN： 2219-2840

  18. Natural History and Chronological Growth Rate of Renal Artery Aneurysms. Peer-reviewed

    Umetsu M, Goto H, Ohara M, Hashimoto M, Shimizu T, Akamatsu D, Tsuchida K, Tajima Y, Suzuki S, Yamamoto K, Miyagi S, Unno M, Kamei T

    Annals of vascular diseases　10　(4)　411-416　2017/12

    DOI： 10.3400/avd.oa.17-00075 　

    ISSN： 1881-641X

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    Objective: Renal artery aneurysm (RAA) is an uncommon disease, the natural course of which is still not well known. The objective of this study is to define factors that affect the growth rate of RAAs. Materials and Methods: We retrospectively reviewed 32 aneurysms in 26 patients at our institute between January 2010 and March 2016. Basal demographics, comorbidities, reason for diagnosis, and details of the aneurysms and interventions were recorded. The chronological changes in the diameter of the RAA using multiplanar reconstructions of computed tomography images were measured and analyzed. Results: The baseline mean diameter was 20.1±8.4 mm (range: 9.9-41). The mean follow-up period was 3.13±2.1 y (range: 0.5-7.1). The median growth rate was 0.35 mm/y (interquartile range: 0.05, 0.62). The growth rate was slower when the initial diameter was <20 mm than when it was >20 mm (p=0.036). Also, whole-completed calcification was a significant factor for slower growth (p=0.016). We performed ex-vivo surgery in two cases and coil packing with stenting in one. No ruptures occurred during the study period. Conclusion: Our results suggest that cases with an RAA diameter <20 mm do not require intervention. The interval period can be longer in whole-completed calcification types.

  19. [A Case of Curatively Resected Ascending Colon Cancer with Ovarian Metastasis and Peritoneal Dissemination after Chemotherapy]. Peer-reviewed

    Yasushi Mochizuki, Hideaki Karasawa, Hideki Shimodaira, Shinobu Ohnuma, Kazuhiro Watanabe, Shimpei Maeda, Munenori Nagao, Takeshi Aoki, Katsuyoshi Kudo, Naoki Tanaka, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno

    Gan to kagaku ryoho. Cancer & chemotherapy　44　(12)　1711-1713　2017/11

    ISSN： 0385-0684

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    A52 -year-old woman was diagnosed with ascending colon cancer with ovarian metastasis and peritoneal dissemination. Since the patient did not have symptoms with intestinal obstruction, mFOLFOX6 plus bevacizumab(Bmab)was performed for 12 cycles. After chemotherapy, the tumors of ascending colon and ovary were significantly shrunken and novel distant metastasis was not observed by CT scans. Therefore, the tumors were considered to be resectable and curative resection was performed. In the surgical findings, the peritoneal disseminations were localized, and right colectomy, bilateral oophorectomy and extirpation of the peritoneal disseminations were performed. R0 resection was pathologically achieved and adjuvant chemotherapy with UFT/UZEL was administrated for 6 months. The patient is alive without recurrence for 1 year. Since right sided colon cancer is less likely to have obstruction, upfront chemotherapy can be a strategy for locally advanced right sided colon cancer with distant metastasis.

  20. [Multidisciplinary Treatment for Squamous Cell Carcinoma of the Anal Canal]. Peer-reviewed

    Hideaki Karasawa, Shinobu Ohnuma, Kazuhiro Watanabe, Takahiro Tsuchiya, Hirofumi Imoto, Takeshi Aoki, Katsuyoshi Kudoh, Naoki Tanaka, Munenori Nagao, Tomoya Abe, Hiroaki Musha, Fuyuhiko Motoi, Takashi Kamei, Takeshi Naitoh, Michiaki Unno

    Gan to kagaku ryoho. Cancer & chemotherapy　44　(12)　2009-2010　2017/11

    ISSN： 0385-0684

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    Chemoradiotherapy(CRT)has been recognized as a standard treatment for locoregional squamous cell carcinoma of the anal canal in Western countries. However, surgery had historically been considered as a standard treatment and there are only a few reports on CRT for anal canal cancer in Japan. In this study, we analyzed medical records of 5 anal canal cancer patients treated with CRT in our hospital between 2005 and 2015. Patients' characteristics were as follows: median age, 70 years (range 42-80 years); male/female, 1/4; and clinical Stage I / III a/ III b, 3/1/1. The regimens of chemotherapy were MMC plus 5-FU in 4 patients and CDDP in 1 patient. The median follow-up period was 30 months(range, 6 to 100 months). After CRT, 4 patients achieved complete response. The other patient with partial response underwent salvage surgery. All patients were alive without recurrence. In conclusion, our retrospective study showed that CRT is considered to be a standard treat- ment for anal canal cancer.

  21. Early-stage primary malignant melanoma of the esophagus detected simultaneously with esophageal squamous cell carcinoma Peer-reviewed

    Makoto Hikage, Takashi Kamei, Fumiyoshi Fujishima, Go Miyata, Ko Onodera, Hirofumi Ichikawa, Toru Hoshida, Hiroshi Kikuchi, Toru Nakano, Jin Teshima, Motoo Fujita, Hironobu Sasano, Susumu Satomi

    ESOPHAGUS　9　(1)　33-38　2012/03

    DOI： 10.1007/s10388-011-0300-x 　

    ISSN： 1612-9059

  22. 切除可能食道癌に対する治療戦略 salvage治療を付加した化学放射線療法と根治手術の成績 Invited Peer-reviewed

    亀井尚, 宮田剛, 小野寺浩, 市川宏文, 菊池寛, 中野徹, 里見進

    臨床消化器内科　26　(10)　1381-1387　2011/08

    Publisher:

    ISSN： 0911-601X

    eISSN： 2433-2488

  23. ナノ粒子を用いた内視鏡手術下蛍光センチネルリンパ生検 Peer-reviewed

    日景允権田幸祐, 武田元博, 亀井尚, 大内憲明

    東北医学雑誌　122　(1)　91-94　2010/06

  24. Nano-imaging of the lymph network structure with quantum dots Peer-reviewed

    Makoto Hikage, Kohsuke Gonda, Motohiro Takeda, Takashi Kamei, Masaki Kobayashi, Masutaka Kumasaka, Mika Watanabe, Susumu Satomi, Noriaki Ohuchi

    NANOTECHNOLOGY　21　(18)　185103　2010/05

    DOI： 10.1088/0957-4484/21/18/185103 　

    ISSN： 0957-4484

  25. 食道癌Salvage Surgeryの適応と合併症対策 Peer-reviewed

    亀井尚, 里見進

    日本気管食道科学会報　61　(2)　99-103　2010/04

    Publisher: The Japan Broncho-esophagological Society

    DOI： 10.2468/jbes.61.99 　

    ISSN： 0029-0645

  26. 食道癌サルベージ手術の評価と今後の展望 Invited

    亀井尚

    外科治療　261-263　2010/03/01

  27. Salvage esophagectomy after failure of definitive chemoradiotherapy for esophageal cancer-Clinical outcomes and Operative indication Invited Peer-reviewed

    Takashi Kamei, S Miyazaki G Miyata, K Onodera, H Ichikawa, T, Hoshida, H Kikuchi, R Kanba, T, Nakano S Satomi

    World Congress of the International Society for diseases of the esophagus　177　2009/10

  28. PROSPECTIVE COMPARISON OF SURGERY ALONE AND CHEMORADIOTHERAPY WITH SELECTIVE SURGERY IN RESECTABLE SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS Peer-reviewed

    Hisanori Ariga, Kenji Nemoto, Shukichi Miyazaki, Takashi Yoshioka, Yohishiro Ogawa, Toru Sakayauchi, Keiichi Jingu, Go Miyata, Ko Onodera, Hirofumi Ichikawa, Takashi Kamei, Shunsuke Kato, Chikashi Ishioka, Susumu Satomi, Shogo Yamada

    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS　75　(2)　348-356　2009/10

    DOI： 10.1016/j.ijrobp.2009.02.086 　

    ISSN： 0360-3016

  29. パルスHo:YAGレーザーを用いた微小ジェットの原理開発と臨床応用 東北大学における医工産学連携の取り組み Peer-reviewed

    中川敦寛, 隈部俊宏, 小川欣一, 平野孝幸, 金森政之, 斎藤竜太, 渡辺みか, 橋本時忠, 中野徹, 亀井尚, 上之原広司, 高山和喜, 冨永悌二

    日本レーザー医学会誌　30　(2)　119-125　2009/07

    Publisher: Japan Society for Laser Surgery and Medicine

    DOI： 10.2530/jslsm.30.119 　

    ISSN： 0288-6200

    More details Close

    Surgical instrument with high tissue selectivity may bring about great improvement in survival and functional outcome by attaining maximal resection and functional preservation of vital structures at the same time. Our research organization consisting of medical, engineering, and company investigators have developed a novel method suitable to generate pulsed micro jet for minimally invasive surgery using holmium: yttrium-aluminum-garnet laser. We have been applying the instrument for various neurosurgical entities and planning to expand its indication to endoscopic surgery. The method not only solved the problems addressed in the continuous pressure-driven waterjet instrument, but also remarkable for using mid-infrared laser as driving force to generate high speed jet.

  30. CRT-saivage治療の成績からみた食道癌初回治療の選択 Invited Peer-reviewed

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    癌の臨床　55　(1)　21-29　2009/01

  31. 食道癌サルベージ手術の周術期管理と合併症予防 Invited Peer-reviewed

    亀井尚, 宮崎修吉

    胸部外科　61　(8)　731-737　2008/07

  32. 食道癌放射線化学療法後のsalvage手術の意義と適応 Invited

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    Jpn J Cancer Clin　53　(10)　647-655　2007/10

  33. Nanosized silver iodide beads as new contrast media for sentinel lymph node navigation surgery. Peer-reviewed

    Sakurai Y, Takeda M, Kawazoe, Y, Kasuya A Kobayashi, Y Kamei T, Nakajima, M, Ohuchi N

    Breast Disease　25　55-56　2006/10

  34. 胸部食道癌の診断と進行度の評価 Invited

    亀井尚, 宮崎修吉, 里見進

    外科治療　95　(3)　229-238　2006/09/01

  35. 新規ナノサイズヨウ化銀ビーズを用いた造影効果とＸ線センチネルリンパ節生検への応用 Peer-reviewed

    桜井遊, 武田元博, 小林芳男, 中島護雄, 亀井尚, 粕谷厚生, 川添良幸, 大内憲明

    乳癌基礎研究　43-47　2006/04

  36. Esophageal gastrointestinal stromal tumors (GISTs): Report of three cases Peer-reviewed

    Takashi Kamei, Shukichi Miyazaki, Go Miyata, Takahiro Mori, Ko Onodera, Hirofumi Ichikawa, Hiroshi Kikuchi, Rikiya Kanba, Susumu Satomi

    Esophagus　2　(4)　209-216　2005/12

    DOI： 10.1007/s10388-005-0057-1 　

    ISSN： 1612-9059 1612-9067

Show all ︎Show first 5

Misc. 5

  1. 経管栄養の考え方と、ナースが押さえておくべき基礎知識 栄養評価 (臨床看護)

    亀井尚, 宮田剛, 里見進

    臨床看護　38　(4)　390-393　2012/03

  2. 【栄養アセスメント 基礎から臨床へ】 生化学検査 脂質 (栄養ー評価と治療)

    亀井尚

    栄養ー評価と治療　28　(2)　140-142　2011/05

  3. 末梢静脈栄養 (日本臨床)

    亀井尚, 里見進

    日本臨床　179-183　2010/03/20

  4. ＣＯＮＵＴとその有用性 (臨床栄養)

    亀井尚, 宮田剛, 小林道生, 鈴木千恵, 阿部裕子, 篠澤洋太郎, 里見進

    臨床栄養　12-16　2009/08/25

  5. salvage esophagectomy after failure of definiyive chemoradioyherapy for esophaeal cancer-clinical outcomes and operative indication (WC of the international society for diseases of the esophagus.)

    Takashi Kamei, S Miyazaki

    WC of the international society for diseases of the esophagus.　177-180　2008/09

Books and Other Publications 1

  1. 消化器外科スタッフマニュアル

    上西紀夫, 平田公一, 里見進, 亀井尚

    中外医学社　2003/10/15

Presentations 106

  1. 胸腔鏡下食道癌手術の手技と成績

    市川宏文, 宮田剛, 小野寺浩, 亀井尚, 菊池寛, 中野徹, 里見進

    第24回日本内視鏡外科学会　2011/12/07

  2. 胸部中部食道に発生した、類基底細胞癌、腺癌、扁平上皮癌成分を併せ持った食道癌の1例

    洞口正志, 先進外科, 藤島史喜, 岡本宏史, 亀井尚, 宮田剛, 里見進

    第73回日本臨床外科学会　2011/11/17

  3. 食道大細胞型内分泌細胞癌の1切除例

    岡本宏史, 移植再建内視鏡外科, 藤島史喜, 宮田剛, 亀井尚, 武山大輔, 洞口正志, 里見進

    第73回日本臨床外科学会　2011/11/17

  4. 消化管内視鏡用パルスジェットメスを用いた安全な食道ESDの開発

    佐藤千晃, 中野徹, 山田誠人, 亀井尚, 宮田剛

    日本レーザー医学会　2011/10/12

  5. サルベージ手術の成績からみた手術適応と合併症の検討

    亀井尚

    第64回日本胸部外科学会　2011/10/09

  6. 動物実験施設を応用した呼吸器外科手術トレーニング

    野田雅史, 市川宏文, 亀井尚, 矢崎伸樹, 近藤丘

    第64回日本胸部外科学会　2011/10/09

  7. Salvage手術の問題点と工夫 食道癌salvage手術の根治性と安全性のバランス

    亀井尚, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 中野徹, 日景允, 武山大輔, 里見進

    第65回日本食道学会　2011/09/26

  8. ステージI食道癌の治療戦略 cStageI食道癌の治療 手術vs根治的化学放射線療法

    亀井尚宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 中野徹, 日景允, 武山大輔, 里見進

    第65回日本食道学会　2011/09/26

  9. 食道癌に対する胸腔鏡下救済手術 手技と成績

    市川宏文, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 中野徹, 里見進

    第65回　2011/09/26

  10. 内視鏡用レーザー誘発パルスウォータージェットメスを用いた安全な食道ESDの開発

    佐藤千晃, 大学院医学研究科外科病態学講座先進外科学, 中野徹, 山田誠人, 中川敦寛, 山本裕朗, 仲井正昭, 亀井尚, 宮田剛, 冨永悌二, 里見進

    第65回日本食道学会　2011/09/26

  11. 根治的CRT後サルベージ手術標本における病理学的因子からみた遺残例・再発例の比較

    岡本宏史, 大学院先進外科, 藤島史喜, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 里見進

    第65回日本食道学会　2011/09/26

  12. AFP産生食道腺癌の3例

    武山大輔, 東北大学病院, 移植再建内視鏡外科, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 藤島史喜, 里見進

    第65回日本食道学会　2011/09/26

  13. 切除可能cStage II、III食道癌における術前化学療法(NAC)、手術単独、化学放射線療法(CRT)の比較

    亀井尚, 大学院先進外科学, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 中野徹, 日景允, 武山大輔, 里見進

    第66回日本消化器外科学会　2011/07/13

  14. 食道胃接合部腺癌の占居部位、リンパ節転移、再発形式からのアプローチ法、切除範囲と郭清範囲の検討(

    中野徹, 大学院先進外科学, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 武山大輔, 日景允, 里見進

    第66回　2011/07/13

  15. 食道癌salvage手術における気管血流を考慮したリンパ節郭清

    小野寺浩, 移植, 再建, 内視鏡外科, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第66回日本消化器外科学会　2011/07/13

  16. 術後回復強化策の努力目標となる回復指標の検討

    宮田剛, 加藤貴志, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 殿塚規夫, 加藤拓見, 佐藤成, 里見進

    第４７回日本外科代謝栄養学会　2011/07/08

  17. 食道癌周術期の早期離床リハビリテーションが水分代謝、蛋白代謝に及ぼす影響

    加藤貴志, 武山大輔, 手島仁, 藤田基生, 日景允, 高橋英幸, 瓶子隆弘, 中野徹, 神波力也, 菊池寛, 星田徹, 亀井尚, 市川宏文, 小野寺浩, 宮崎修吉, 宮田剛, 佐藤成, 里見進

    第４６回日本外科代謝栄養学会　2011/07/08

  18. cStage II,III食道癌に対する術前化学療法と手術単独、化学放射線療法の比較

    亀井尚, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 中野徹, 里見進

    第６３回日本胸部外科学会　2010/10/24

  19. 蛍光内視鏡下手術の開発

    亀井尚, 日景允, 武田元博, 中川智彦, 新妻近展, 大内憲明, 里見進

    第２３回日本内視鏡外科学会　2010/10/18

  20. 切除可能食道癌に対する治療戦略ーsalvage治療を付加した化学放射線療法と根治手術の成績

    亀井尚, 宮田剛, 里見進

    ＪＤＤＷ２０１０　2010/10/13

  21. Definitive chemoradiotherapy followed by salvage treatment for clinical stage I squamous cell cancer of the esophagus International-presentation

    Takashi Kamei, G. Miyata, K. Onodera, H.Ichikawa, T.Hoshida, H.Kikuchi, T.Nakano, S.Satomi

    ＩＳＤＥ2010　2010/09/02

  22. 食道温存を目指したcStageI食道癌に対する治療戦略

    亀井尚, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 中野徹, 日景允, 手島仁, 里見進

    第６４回日本食道学会　2010/08/31

  23. 原発巣ＣＲで106recR郭清を行った３例

    小野寺浩, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６４回日本食道学会　2010/08/31

  24. 食道癌に対する胸腔鏡下salvage手術の長期成績

    市川宏文, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 中野徹, 日景允, 手島仁, 里見進

    第６４回日本食道学会　2010/08/31

  25. 当科における食道胃接合部腺癌の手術症例の検討

    中野徹, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 日景允, 手島仁, 里見進

    第６４回日本食道学会　2010/08/31

  26. 胸腔鏡下食道切除を行った巨大食道神経鞘腫の１例

    手島仁, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 日景允, 里見進

    第６４回日本食道学会　2010/08/31

  27. 食道貯留嚢胞の１例

    神波力也, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 里見進

    第６４回日本食道学会　2010/08/31

  28. 食道癌salvage手術の現時点での評価

    亀井尚, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 中野徹, 里見進

    第６５回日本消化器外科学会　2010/07/14

  29. 術前合併症を有する食道癌の治療の検討

    星田徹, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 中野徹, 日景允, 手島仁, 里見進

    第６５回日本消化器外科学会　2010/07/14

  30. 食道穿孔に対する胸腔鏡下手術６例の検討

    市川宏文, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 中野徹, 日景允, 手島仁, 里見進

    第６５回日本消化器外科学会　2010/07/14

  31. 胸部疾患に伴う食道穿孔の７治療例

    中野徹, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 日景允, 手島仁, 里見進

    第６５回日本消化器外科学会　2010/07/14

  32. 当科における腹腔鏡下食道アカラシア手術

    神波力也, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 渋谷俊介, 里見進

    第６５回日本消化器外科学会　2010/07/14

  33. 食道癌salvage手術における気管血流を考慮したリンパ節郭清

    小野寺浩, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 日景允, 手島仁, 里見進

    第６５回日本消化器外科学会　2010/07/14

  34. 胸腔鏡下食道切除術における画像診断技術の応用

    市川宏文, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 瓶子隆弘, 高橋英幸, 加藤拓見, 里見進

    第１１０回日本外科学会　2010/04/08

  35. ナノスケール蛍光粒子を用いた革新的センチネルリンパ節イメージング

    日景允, 武田元博, 亀井尚, 権田幸祐, 小林正樹, 熊坂増高, 渡辺みか, 里見進, 大内憲明

    第１１０回日本外科学会　2010/04/08

  36. 新規蛍光ナノ粒子を用いた蛍光内視鏡下手術の開発と基礎実験

    亀井尚, 日景允, 中野徹, 武田元博, 中川智彦, 大内憲明, 宮田剛, 里見進

    第２２回日本内視鏡外科学会　2009/12/03

  37. 胸腔鏡下食道切除術における画像診断技術の応用

    市川宏文, 加藤拓見, 森田佳明, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第２２回日本内視鏡外科学会　2009/12/03

  38. 食道癌salvage surgeryの適応と合併症対策

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６１回日本気管食道科学会　2009/11/05

  39. 食道癌salvage 手術の適応と合併症対策

    亀井尚, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 宮崎修吉, 里見進

    第６２回日本胸部外科学会　2009/10/11

  40. cStage(T1bN0M0)食道癌に対するＣＲＴ+salvage治療ー食道温存率と成績

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６４回日本消化器外科学会　2009/07/16

  41. 食道癌に対する胸腔鏡下salvage手術

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６４回日本消化器外科学会　2009/07/16

  42. 当科におけるStageII ,III食道癌に対する治療戦略

    小野寺浩, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６４回日本消化器外科学会　2009/07/16

  43. 当科における食道癌深達度診断の精度の検討

    星田徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 神波力也, 中野徹, 里見進

    第６４回日本消化器外科学会　2009/07/16

  44. 食道癌salvage手術の適応と周術期管理

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６３回日本食道学会　2009/06/25

  45. 食道癌の標準手術としての胸腔鏡下食道切除術

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第６３回日本食道学会　2009/06/25

  46. 食道癌根治的化学放射線療法後の晩期合併症の検討

    星田徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 神波力也, 中野徹, 里見進

    第６３回日本食道学会　2009/06/25

  47. 下咽頭癌術後の食道癌の治療についての検討

    中野徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進

    第６３回日本食道学会　2009/06/25

  48. ＣＲＴ+salvage治療の成績からみた食道癌初回治療の選択

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第１０お９回日本外科学会　2009/04/02

  49. 食道癌に対する胸腔鏡下食道切除術の手術手技と成績

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第１０９回日本外科学会　2009/04/02

  50. 胸部食道癌手術後に生じた再建胃管癌の治療経験についての検討

    中野徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進

    第１０９回日本外科学会　2009/04/02

  51. ナノ粒子を用いたセンチネルリンパ節生検の基礎的検討

    日景允, 亀井尚, 武田元博, 小林正樹, 中野徹, 櫻井遊, 河合賢朗, 濱中洋平, 熊坂増高, 宮田剛, 宮崎修吉, 里見進, 大内憲明

    第１０９回日本外科学会　2009/04/02

  52. 自律的改善を目的とした東北大学NST戦略マップ

    宮田剛, 菅原恵, 柴田近, 亀井尚, 柴田弘子, 梁川陽子, 布施早季, 神波力也, 久道周彦, 鈴木千恵, 鈴木信一, 白砂たま子, 岡本智子, 佐々木巌, 里見進

    第24回日本静脈経腸栄養学会　2009/01/29

  53. 肥満患者は食道癌手術後の炎症反応が強いか?

    宮田剛, 宮崎修吉, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 阿部薫夫, 萩原資久, 里見進

    第４４回日本外科代謝栄養学会　2008/10/29

  54. salvage esophagectomy after failure of definitive chemoradiotherapy for esophageal cancer International-presentation

    Kamei T, Miyazaki S, Miyata G

    11th World Congress of the International Society for Disease of the Esophagus　2008/09/10

  55. 新規ナノ粒子をトレーサーとした蛍光内視鏡下手術の基礎的検討

    日景允, 亀井尚, 武田元博, 小林正樹, 中野徹, 櫻井遊, 河合賢朗, 叢莉蔓, 宮田剛, 宮崎修吉, 里見進, 大内憲明

    第21回日本内視鏡外科学会　2008/09/02

  56. Basic examination of the fluorescent endoscopic surgery using new nanoparticle tracer International-presentation

    Hikage M, Kamei T, Takede M

    11th World Congress of Endoscopic Surgery　2008/09/02

  57. Stage I食道癌に対する手術とCRTの治療成績の比較

    小野寺浩, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 星田徹, 中野徹, 菊池寛, 神波力也, 里見進

    第63回日本消化器外科学会　2008/07/16

  58. 魚骨により食道穿孔をきたした一例

    中野徹, 宮田剛, 宮崎修吉, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進

    第63回日本消化器外科学会　2008/07/16

  59. 食道癌のサルベージサージャリーの問題 食道癌salvage手術の評価と今後の展望

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第63回日本消化器外科学会　2008/07/16

  60. 食道穿孔に対する胸腔鏡手術5例の検討

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第62回日本食道学会　2008/06/21

  61. 成績、再発形式からみたsalvage手術におけるリンパ節郭清の意義

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第62回日本食道学会　2008/06/21

  62. 当院における食道原発悪性黒色腫の検討

    神波力也, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 中野徹, 里見進

    第62回日本食道学会　2008/06/21

  63. 食道類基底細胞（扁平上皮）癌の14例の検討

    武山大輔, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 藤島史喜, 笹野公伸, 里見進

    第62回日本食道学会　2008/06/21

  64. 当科におけるBarrett食道癌の手術症例の検討

    中野徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進

    第62回日本食道学会　2008/06/21

  65. 食道癌根治術後再発症例の検討

    萩原資久, 上村卓爾, 桂一憲, 桜井直, 中野徹, 神波力也, 菊池寛, 星田徹, 亀井尚, 市川宏文, 小野寺浩, 宮田剛, 宮崎修吉, 里見進

    第62回日本食道学会　2008/06/21

  66. 降下性壊死性縦隔炎6例の検討

    神波力也, 中野徹, 菊池寛, 星田徹, 亀井尚, 市川宏文, 小野寺浩, 宮田剛, 宮崎修吉, 里見進

    第108回日本外科学会　2008/05/15

  67. 胸部食道癌切除術後に生じた再建胃管癌の治療経験についての検討

    中野徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進

    第108回日本外科学会　2008/05/15

  68. ナノ粒子を用いたセンチネルリンパ節生検の基礎的検討

    日景允, 亀井尚, 武田元博, 小林正樹, 中野徹, 櫻井遊, 河合賢朗, 叢莉蔓, 濱中洋平, 熊坂増高, 宮田剛, 宮崎修吉, 里見進, 大内憲明

    第108回日本外科学会　2008/05/15

  69. 食道癌の根治治療 手術療法vs.化学放射線療法 日本におけるエビデンスは? CRT+salvage治療の成績から見た食道癌初回治療の選択 手術単独との比較

    亀井尚, 先進外科, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第108回日本外科学会　2008/05/15

  70. 鏡視下食道癌手術を安全に行うための手技と工夫 食道癌に対する胸腔鏡下食道切除術の手術手技と成績

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 萩原資久, 瓶子隆弘, 高橋一臣, 高橋英幸, 里見進

    第108回日本外科学会　2008/05/15

  71. 当科における腹腔鏡下食道アカラシア手術 X線型による工夫

    神波力也, 渋谷俊介, 中野徹, 菊池寛, 亀井尚, 市川宏文, 小野寺浩, 宮田剛, 宮崎修吉, 里見進

    第108回日本外科学会　2008/05/15

  72. 食道腺癌の切除症例の検討

    中野徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 桂一憲, 櫻井直, 萩原資久, 里見進

    第108回日本外科学会　2008/05/15

  73. 化学放射線治療後の食道扁平上皮癌におけるFDG-PET診断の検討

    菊池寛, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 神波力也, 中野徹, 桂一憲, 櫻井直, 萩原資久, 上村卓嗣, 里見進

    第108回日本外科学会　2008/05/15

  74. 食道癌に対する胸腔鏡下食道切除術の手技と成績

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 里見進

    第108回日本外科学会　2008/05/15

  75. 胸部食道癌に対する放射線化学療法後の再発様式の検討

    小野寺浩, 大内憲明, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 中野徹, 櫻井直, 桂一憲, 萩原資久, 里見進

    第108回日本外科学会　2008/05/15

  76. 栄養評価におけるCONUT値の有用性と位置づけ

    鈴木千恵, 朝倉徹, 阿部裕子, 岡本智子, 日野美代子, 中山眞紀, 稲村なお子, 菅原恵, 高橋美貴子, 武田みゆき, 瀬田拓, 小林道生, 神波力也, 亀井尚, 柴田近, 宮田剛

    日本静脈経腸栄養学会　2008/02/21

  77. ＣＲＰとＡＬＢ，ChEの関連からみた侵襲期タンパク合成優先順位に関する検討

    宮田剛, 宮崎修吉, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 神波力也, 阿部薫夫, 谷山裕亮, 里見進

    第４３回日本外科代謝栄養学会　2007/10/23

  78. 切除可能胸部食道癌に対する根治的化学放射線療法とsalvage手術

    小野寺浩, 大内憲明, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進, 小川芳弘, 山田章吾, 吉岡孝志

    第６０回日本胸部外科学会　2007/10/17

  79. 降下性壊死性縦隔炎の５例の検討

    上村卓嗣, 宮田剛, 小野寺浩, 市川宏文, 星田徹, 亀井尚, 菊池寛, 神波力也, 中野徹, 桜井直, 宮崎修吉, 里見進

    第６０回日本胸部外科学会　2007/10/17

  80. 食道癌salvage手術の適応と問題点

    亀井尚, 宮崎修吉

    第６２回日本消化器外科学会　2007/07/18

  81. 頸部食道癌に対する化学放射線療法 手術との治療成績の比較

    小野寺浩, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 阿部薫夫, 里見進

    第６２回日本消化器外科学会　2007/07/18

  82. 当科における腹腔鏡下食道アカラシア手術30例の検討

    神波力也, 渋谷俊介, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 里見進

    第６２回日本消化器外科学会　2007/07/18

  83. 消化器外科手術における画像診断の新展開 胸腔鏡下食道切除術の術前3D-CTシミュレーション

    市川宏文, 宮崎修吉, 宮田剛, 小野寺浩, 亀井尚, 星田徹, 菊池寛, 神波力也, 里見進

    第６２回日本消化器外科学会　2007/07/18

  84. Ｔ１ｂ食道癌の治療戦略

    亀井尚, 宮崎修吉

    第６１回日本食道学会　2007/06/21

  85. 切除可能stageII,III胸部食道癌に対するＣＲＴ

    小野寺浩, 大内憲明, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 阿部薫夫, 里見進, 小川芳弘, 山田章吾, 吉岡孝志

    第６１回日本食道学会　2007/06/21

  86. 悪性黒色腫4例の検討

    神波力也, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 阿部薫夫, 渋谷俊介, 矢島美穂子, 里見進

    第６１回日本食道学会　2007/06/21

  87. FDG-PETによる食道扁平上皮癌術前診断の検討

    菊池寛, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 神波力也, 阿部薫夫, 里見進

    第６１回日本食道学会　2007/06/21

  88. ESDにて診断しえた食道癌放射線化学療法後局所再発の1例

    星田徹, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 神波力也, 阿部薫夫, 里見進

    第６１回日本食道学会　2007/06/21

  89. 食道癌salvage手術後に気管壊死を来たした３症例の検討

    阿部薫夫, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 亀井尚, 星田徹, 菊池寛, 神波力也, 桜井直, 上村卓嗣, 里見進

    第６１回日本食道学会　2007/06/21

  90. 食道癌根治的放射線化学療法後のsalvage手術の意義と適応

    亀井尚, 宮崎修吉

    第１０７回日本外科学会　2007/04/11

  91. 切除可能食道癌に対する根治低的化学放射線療法とsalvage手術

    小野寺浩, 宮崎修吉, 宮田剛, 市川宏文, 亀井尚, 菊池寛, 神波力也, 阿部薫夫, 大内憲明, 里見進, 小川芳弘, 山田章吾, 吉岡孝志

    第107回日本外科学会　2007/04/11

  92. 食道癌手術における腹腔鏡補助下およびＨＡＬＳ胃管作成術

    亀井尚, 宮崎修吉, 宮田剛, 小野寺浩, 市川宏文, 菊池寛, 神波力也, 阿部薫夫, 里見進

    第１９回日本内視鏡外科学会　2006/12/05

  93. 食道癌に対する根治的放射線化学療法後のsalvage手術

    亀井尚

    東北消化器周術期研究会　2006/11/17

  94. 癌領域における分子イメージングの現状と今後の展望

    武田元博, 中島護雄, 小林芳男, 小林正樹, 桜井遊, 亀井尚, 叢莉蔓, 甘利正和, 粕谷厚生, 石田孝宣, 鈴木昭彦, 大内憲明

    第６５回日本癌学会　2006/09/28

  95. 食道癌に対する根治的放射線化学療法後、非奏功例へのsalvage手術

    亀井尚, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 市川宏文, 菊池寛, 神波力也, 阿部薫夫, 里見進

    第６１回日本消化器外科学会　2006/07/13

  96. 肝におけるタンパク合成優先順位の観点からみた術後栄養指標の検討

    宮田剛, 森隆弘, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 神波力也, 村上和重, 宮崎修吉, 里見進

    第６１回日本消化器外科学会　2006/07/13

  97. 当科における食道胃接合部癌の外科治療成績の検討

    菊池寛, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 市川宏文, 亀井尚, 神波力也, 阿部薫夫, 里見進

    第６１回日本消化器外科学会　2006/07/13

  98. 胸腔鏡下食道切除術における術前３Ｄ？ＣＴの有用性〜気管血流に配慮した手術

    市川宏文, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 亀井尚, 菊池寛, 神波力也, 森田佳明, 里見進

    第６１回日本消化器外科学会　2006/07/13

  99. 新規ナノサイズヨウ化銀ビーズを用いたＸ線センチネルリンパ節の造影効果と体内動態の検討

    桜井遊, 小林芳男, 亀井尚, 中島護雄, 川添良幸, 粕谷厚生, 甘利正和, 鈴木昭彦, 石田孝宣, 大内憲明

    第１４回日本乳癌学会　2006/07/07

  100. CRPとALB,ChEの関連から見た侵襲期蛋白合成優先順位に関する検討

    宮田剛, 宮崎修吉, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 神波力也, 阿部薫夫, 谷山裕亮, 里見進

    第４３回日本外科代謝栄養学会　2006/07/05

  101. 根治的放射線化学療法非奏功例に対する食道癌salvage手術の検討

    亀井尚, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 市川宏文, 菊池寛, 神波力也, 阿部薫夫, 里見進

    第６０回日本食道学会　2006/06/30

  102. 当科における食道アカラシア手術２８例の検討

    神波力也, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 市川宏文, 亀井尚, 菊池寛, 阿部薫夫, 里見進

    第６０回日本食道学会　2006/06/30

  103. NPC/Nの低い経腸栄養剤投与によると思われる高ＢＵＮ血症の２例

    宮田剛, 森隆弘, 市川宏文, 小野寺浩, 亀井尚, 神波力也, 菊池寛, 村上和重, 阿部薫夫, 谷山裕亮, 宮崎修吉, 里見進

    第６０回日本食道学会　2006/06/30

  104. 食道穿孔に対する胸腔鏡手術の有用性

    市川宏文, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 亀井尚, 菊池寛, 神波力也, 阿部薫夫, 里見進

    第６０回日本食道学会　2006/06/29

  105. 食道癌手術におけるHALS胃管作成術

    亀井尚, 宮崎修吉, 宮田剛, 森隆弘, 小野寺浩, 市川宏文, 菊池寛, 神波力也, 里見進

    第４回ミニラパ研究会　2006/05/27

  106. ガドリニウムナノ粒子を用いた新規ＭＲＩ造影剤の基礎的検討

    武田元博, 小林芳男, 桜井遊, 中島護雄, 叢莉蔓, 菅原旭浩, 亀井尚, 甘利正和, 粕谷厚生, 大内憲明

    第１０６回日本外科学会　2006/03/29

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  1. 炎症関連因子遺伝子多型と各種固形癌の進展度・予後に関する研究

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    食道癌患者のCRP遺伝子のSNPsを調べ、リンパ節転移予測を行うもの

  2. 蛍光ナノ粒子を用いた蛍光ナビゲーション内視鏡下手術システムの検討

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    蛍光内視鏡手術システムの開発