Details of the Researcher

PHOTO

Ma Aobo
Section
Graduate School of Dentistry
Job title
Assistant Professor
Degree

  • PhD (Dental Science) (Tohoku University)

e-Rad No.
81019355

Research History 2

  • 2026/01 - Present
    アイルランガ大学　歯学研究科・歯科補綴学　非常勤教授

  • 2025/04 - Present
    東北大学大学院歯学研究科・歯学部　国際連携イノベイティブ歯学分野　助教

Education 3

  • Tohoku University　Graduate School of Dentistry　Department of Dentistry

    2020/10 - 2025/03

  • Tianjin Medical University　Graduate School of Dentistry

    2017/09 - 2020/06

  • Hebei Medical University　School of Dentistry

    2012/09 - 2017/06

Professional Memberships 3

  • 日本歯科理工学会

    2026/06 - Present

  • 日本補綴歯科学会

    2026/06 - Present

  • International Association for Dental Research (IADR)

    2025 - Present

Research Interests 3

  • 骨生物学

  • biomaterial

  • Dental implant

Research Areas 1

  • Life sciences / Regenerative dentistry and dental engineering /

Awards 4

  1. 優秀学位研究賞

    2025/03　東北大学歯学研究科

  2. 東北大学高等大学院博士学生フェローシップ

    2022/04　東北大学

  3. 東北大学藤野先生記念奨励賞

    2021/09　東北大学

  4. 東北大学外国人留学生総長特別奨学生

    2021/04　東北大学

Papers 14

  1. Diagnostic accuracy and feasibility of artificial intelligence-driven smartphone imaging for dental caries detection: A systematic review Peer-reviewed

    Joseph Macadaeg Acosta, Alexander Patera Nugraha, Kunhua Yang, Juan Ramón Vanegas Sáenz, Aobo Ma, Pagaporn Pantuwadee Pisarnturakit, Guang Hong

    Japanese Dental Science Review　62　14-25　2026/12

    Publisher: Elsevier BV

    DOI： 10.1016/j.jdsr.2025.11.001 　

    ISSN： 1882-7616

  2. Oral Health-related Quality of Life Among 2SLGBTQIAPN+: A Systematic Review Peer-reviewed

    Win Myat Phyo, Aobo Ma, Palinee Detsomboonrat, Juan Ramón Vanegas Sáenz, Duangporn Duangthip, Guang Hong

    International Dental Journal　76　(4)　109624-109624　2026/08

    Publisher: Elsevier BV

    DOI： 10.1016/j.identj.2026.109624 　

    ISSN： 0020-6539

  3. Mechanical and biological properties of cellulose nanofibers as a dental biomaterial Peer-reviewed

    Junduo Chen, Aobo Ma, Yiding Zhang, Lu Sun, Kunhua Yang, Juan Ramón Vanegas Sáenz, Guang Hong

    Journal of Dental Sciences　2025

    DOI： 10.1016/j.jds.2025.02.006 　

    ISSN： 1991-7902

    eISSN： 2213-8862

  4. Differential expression of osteoblast-like cells on self-organized titanium dioxide nanotubes Peer-reviewed

    Aobo Ma, Yiding Zhang, Junduo Chen, Lu Sun, Guang Hong

    JOURNAL OF DENTAL SCIENCES　19　S26-S37　2024/12

    DOI： 10.1016/j.jds.2024.09.001 　

    ISSN： 1991-7902

    eISSN： 2213-8862

  5. Nanoclay-Modified Hyaluronic Acid Microspheres for Bone Induction by Sustained rhBMP-2 Delivery. International-journal

    Yi-Ding Zhang, Ao-Bo Ma, Lu Sun, Jun-Duo Chen, Guang Hong, Hong-Kun Wu

    Macromolecular bioscience　24　(2)　e2300245　2024/02

    DOI： 10.1002/mabi.202300245 　

    More details Close

    Microspheres (MSs) are ideal candidates as biological scaffolds loading with growth factors or cells for bone tissue engineering to repair irregular alveolar bone defects by minimally invasive injection. However, the high initial burst release of growth factor and low cell attachment limit the application of microspheres. The modification of microspheres often needs expensive experiments facility or complex chemical reactions, which is difficult to achieve and may bring other problems. In this study, a sol-grade nanoclay, laponite XLS is used to modify the surface of MSs to enhance its affinity to either positively or negatively charged proteins and cells without changing the interior structure of the MSs. Recombinant human bone morphogenetic protein-2 (rhBMP-2) is used as a representation of growth factor to check the osteoinduction ability of laponite XLS-modified MSs. By modification, the protein sustained release, cell loading, and osteoinduction ability of MSs are improved. Modified by 1% laponite XLS, the MSs can not only promote osteogenic differentiation of MC3T3-E1 cells by themselves, but also enhance the effect of the rhBMP-2 below the effective dose. Collectively, the study provides an easy and viable method to modify the biological behavior of microspheres for bone tissue regeneration.

  6. β-Tricalcium Phosphate as Alveolar Bone Grafting in Cleft Lip/Palate: A Systematic Review

    Alexander Patera Nugraha, Hui Yang, Junduo Chen, Kunhua Yang, Ploypim Kraisintu, Kyaw Zaww, Aobo Ma, Ruixian Wang, Nada Emad Alshafei Mohamed Alhadi, Juan Ramon Vanegas Saenz, Guang Hong

    DENTISTRY JOURNAL　11　(10)　2023/10

    DOI： 10.3390/dj11100234 　

    eISSN： 2304-6767

  7. Icariin/Aspirin Composite Coating on TiO2 Nanotubes Surface Induce Immunomodulatory Effect of Macrophage and Improve Osteoblast Activity

    Aobo Ma, Yapeng You, Bo Chen, Wanmeng Wang, Jialin Liu, Hui Qi, Yunkai Liang, Ying Li, Changyi Li

    COATINGS　10　(4)　2020/04

    DOI： 10.3390/coatings10040427 　

    eISSN： 2079-6412

  8. Zn-Incorporated TiO2 Nanotube Surface Improves Osteogenesis Ability Through Influencing Immunomodulatory Function of Macrophages

    Bo Chen, Yapeng You, Aobo Ma, Yunjia Song, Jian Jiao, Liting Song, Enyu Shi, Xue Zhong, Ying Li, Changyi Li

    INTERNATIONAL JOURNAL OF NANOMEDICINE　15　2095-2118　2020

    DOI： 10.2147/IJN.S244349 　

    ISSN： 1178-2013

  9. Icariin-Functionalized Coating on TiO2 Nanotubes Surface to Improve Osteoblast Activity In Vitro and Osteogenesis Ability In Vivo

    Aobo Ma, Haiyan Shang, Yunjia Song, Bo Chen, Yapeng You, Wen Han, Xu Zhang, Wenyi Zhang, Ying Li, Changyi Li

    COATINGS　9　(5)　2019/05

    DOI： 10.3390/coatings9050327 　

    ISSN： 2079-6412

  10. Improved osteoblast adhesion and osseointegration on TiO2 nanotubes surface with hydroxyapatite coating

    Ying Li, Baoe Li, Yunjia Song, Aobo Ma, Changyi Li, Xu Zhang, Hongjie Li, Qian Zhang, Kai Zhang

    DENTAL MATERIALS JOURNAL　38　(2)　278-286　2019/04

    DOI： 10.4012/dmj.2018-118 　

    ISSN： 0287-4547

  11. Type i collagen combined titanium dioxide nanotube composite coating modified titanium surface improves osteoblast adhesion and osseointegration

    Ying Li, Yapeng You, Baoe Li, Yunjia Song, Aobo Ma, Bo Chen, Wen Han, Changyi Li

    Chinese Journal of Tissue Engineering Research　23　(14)　2169-2176　2019

    DOI： 10.3969/j.issn.2095-4344.1669 　

    ISSN： 2095-4344

  12. Improved Cell Adhesion and Osseointegration on Anodic Oxidation Modified Titanium Implant Surface

    Ying Li, Yapeng You, Baoe Li, Yunjia Song, Aobo Ma, Bo Chen, Wen Han, Changyi Li

    JOURNAL OF HARD TISSUE BIOLOGY　28　(1)　13-20　2019/01

    DOI： 10.2485/jhtb.28.13 　

    ISSN： 1341-7649

  13. Surface Immobilization of TiO2 Nanotubes with Bone Morphogenetic Protein-2 Synergistically Enhances Initial Preosteoblast Adhesion and Osseointegration

    Ying Li, Yunjia Song, Aobo Ma, Changyi Li

    BIOMED RESEARCH INTERNATIONAL　2019　2019

    DOI： 10.1155/2019/5697250 　

    ISSN： 2314-6133

    eISSN： 2314-6141

  14. Loading icariin on titanium surfaces by phase-transited lysozyme priming and layer-by-layer self-assembly of hyaluronic acid/chitosan to improve surface osteogenesis ability

    Yunjia Song, Aobo Ma, Jia Ning, Xue Zhong, Qian Zhang, Xu Zhang, Guang Hong, Ying Li, Keiichi Sasaki, Changyi Li

    INTERNATIONAL JOURNAL OF NANOMEDICINE　13　6751-6767　2018

    DOI： 10.2147/IJN.S174953 　

    ISSN： 1178-2013

Show all ︎Show first 5

Presentations 2

  1. Nanotube Mediates Human Osteoblast-like Cell Proliferation and Differentiation

    MA AB, CHEN JD, HONG G.

    2023/11/25

  2. Icariin/Aspirin Composite Coating on TiO2 Nanotubes Surface Induce Immunomodulatory Effect of Macrophage and Improve Osteoblast Activity.

    MA AB, HONG G.

    TU-HKU-FJMU International Symposium on Oral Health Sciences 2022　2022/11/17

Research Projects 3

  1. TiO2ナノチューブを用いた生物模倣歯周膜の構築

    MA AOBO

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究

    Institution: 東北大学

    2026/04 - 2029/03

  2. Development of a Titanium Dioxide Nanotube-Based Model for Personalized Bone Regeneration Implants

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Research Activity Start-up

    Institution: Tohoku University

    2025/07/31 - 2027/03/31

  3. Study of exosomes’ secretion and function influenced by nanotube topography

    Offer Organization: 科学技術振興機構 (JST)

    System: JST次世代研究者挑戦的研究プログラム

    2022/04 - 2025/03