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博士(工学)(慶應義塾大学)
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修士(工学)(慶應義塾大学)
Details of the Researcher
Research History 7
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2025/04 - PresentKeio University Graduate School of Science and Technology
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2025/04 - PresentTohoku University Graduate School of Biomedical Engineering Assistant Professor
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2024/07 - Present慶應義塾湘南藤沢中高等部 臨時職員
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2022/04 - 2025/03Keio University Graduate School of Science and Technology
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2022/04 - 2025/03Japan Society for the Promotion of Science Research Fellowship for Young Scientists PD
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2020/04 - 2022/03Japan Society for the Promotion of Science Research Fellowship for Young Scientists DC2
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2019/04 - 2020/03Keio University Graduate School of Science and Technology Assistant Professor (Defined term, Research Encouraged)
Education 3
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Keio University Graduate School of Science and Technology School of Integrated Design Engineering
2019/04 - 2022/03
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Keio University Graduate School of Science and Technology School of Integrated Design Engineering
2017/04 - 2019/03
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Keio University Faculty of Science and Technology Department of Mechanical Engineering
2013/04 - 2017/03
Committee Memberships 3
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日本生体医工学会 若手WG幹事
2024/05 - Present
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日本生体医工学会 理事会幹事
2023/09 - Present
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Japanese Society for Medical and Biological Engineering Working group of young researcheres
2022/06 - Present
Professional Memberships 4
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Japanese Society for Medical and Biological Engineering
2021/05 - Present
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The Japanese Society for Regenerative Medicine
2020/02 - Present
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化学とマイクロ・ナノシステム学会
2018/08 - Present
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The Japan Society of Mechanical Engineers
2017/05 - Present
Research Interests 5
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機械学習
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血流解析
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Tissue Engineered Blood Vessel
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Biomedical Engineering
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Tissue Engineering
Research Areas 3
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Nanotechnology/Materials / Material fabrication and microstructure control /
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Life sciences / Biomedical engineering /
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Manufacturing technology (mechanical, electrical/electronic, chemical engineering) / Machine materials and mechanics /
Awards 11
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Inoue Research Award for Young Scientists
2025/02 Inoue Foundation for Science
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優秀研究賞
2024/11 化学とマイクロ・ナノシステム学会 螺旋状の高密度平滑筋層を含有し生理的収縮弛緩機能を実現したiPS由来人工血管による老化病態再現
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Catalyst Award
2024/09 U.S. National Academy of Medicine Aiming for Vascular Regeneration and Rejuvenation Using iPSC-3D Vasculature
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CBMS Student/Young Researcher Travel Grant
2024/09 Chemical and Biological Microsystems Society AN iPSC-BLOOD VESSEL WITH SPIRALLY ORIENTED SMOOTH MUSCLE MIMIC AGING PHENOTYPES IN PHYSIOLOGICAL FUNCTION AND METABOLITES
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ベストポスターアワード
2024/09 日本生体医工学会 螺旋状に配向した高密度平滑筋層を持つiPS由来人工血管を用いた血管収縮・弛緩機能における病態再現
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Fujiwara Award
2022/03 Keio University
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Grand Prize of Young Investigator’s Award
2021/06 Japanese Society for Medical and Biological Engineering
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Outstanding Presentation Award
2018/11 Society for Chemistry and Micro-Nano Systems
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Outstanding Presentation Award of Young Fellow
2018/06 The Japan Society of Mechanical Engineers
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Outstanding poster award
2017/11 The Institute of Electrical Engineers of Japan
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Kito Award
2017/03 Keio University
Papers 17
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Maturation of Human iPSC‐Derived Cardiac Microfiber with Electrical Stimulation Device Peer-reviewed
Akari Masuda, Yuta Kurashina, Hidenori Tani, Yusuke Soma, Jumpei Muramatsu, Shun Itai, Shugo Tohyama, Hiroaki Onoe
Advanced Healthcare Materials 2024/05/29
Publisher: WileyISSN: 2192-2640
eISSN: 2192-2659
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Hydrogel‐Sheathed hiPSC‐Derived Heart Microtissue Enables Anchor‐Free Contractile Force Measurement Peer-reviewed
Yuta Kurashina, Keisuke Fukada, Shun Itai, Shuichi Akizuki, Ryo Sato, Akari Masuda, Hidenori Tani, Jun Fujita, Keiichi Fukuda, Shugo Tohyama, Hiroaki Onoe
Advanced Science 10 (35) 2023/10/17
Publisher: WileyISSN: 2198-3844
eISSN: 2198-3844
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Schwann cell-encapsulated chitosan-collagen hydrogel nerve conduit promotes peripheral nerve regeneration in rodent sciatic nerve defect models Peer-reviewed
Hiroaki Takeya, Shun Itai, Hiroo Kimura, Yuta Kurashina, Tsuyoshi Amemiya, Narihito Nagoshi, Takuji Iwamoto, Kazuki Sato, Shinsuke Shibata, Morio Matsumoto, Hiroaki Onoe, Masaya Nakamura
Scientific Reports 13 (1) 2023/07/24
Publisher: Springer Science and Business Media LLCDOI: 10.1038/s41598-023-39141-2
eISSN: 2045-2322
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Unusual Selective Monitoring of N,N-Dimethylformamide in a Two-Dimensional Material Field-Effect Transistor Peer-reviewed
Akito Fukui, Keigo Matsuyama, Hiroaki Onoe, Shun Itai, Hidekazu Ikeno, Shunsuke Hiraoka, Kousei Hiura, Yuh Hijikata, Jenny Pirillo, Takahiro Nagata, Kuniharu Takei, Takeshi Yoshimura, Norifumi Fujimura, Daisuke Kiriya
ACS Nano 2023/07/17
Publisher: American Chemical Society (ACS)ISSN: 1936-0851
eISSN: 1936-086X
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Flexibly Deformable Collagen Hydrogel Tube Reproducing Immunological Tissue Deformation of Blood Vessels as a Pharmacokinetic Testing Model Peer-reviewed
Shun Itai, Hiroaki Onoe
Advanced Healthcare Materials 11 (1) 2101509-2101509 2022/10/25
Publisher: WileyISSN: 2192-2640
eISSN: 2192-2659
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Janus Hydrogel Microbeads for Glucose Sensing with pH Calibration Peer-reviewed
Maru Ando, Mio Tsuchiya, Shun Itai, Tomomi Murayama, Yuta Kurashina, Yun Jung Heo, Hiroaki Onoe
Sensors 21 (14) 4829-4829 2021/07/15
Publisher: MDPI AGDOI: 10.3390/s21144829
eISSN: 1424-8220
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Endothelial Chemical Reaction and Drug Test Reproduced on Molded Flexible Collagen Hydrogel Tube
Shun Itai, Hiroaki Onoe
21st International Conference on Solid-State Sensors, Actuators and Microsystems, TRANSDUCERS 2021 283-286 2021/06/20
Publisher: Institute of Electrical and Electronics Engineers Inc.DOI: 10.1109/Transducers50396.2021.9495658
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Travelling ultrasound promotes vasculogenesis of three‐dimensional‐monocultured human umbilical vein endothelial cells Peer-reviewed
Chikahiro Imashiro, Tetsuya Azuma, Shun Itai, Taiki Kuribara, Kiichiro Totani, Hiroaki Onoe, Kenjiro Takemura
Biotechnology and Bioengineering 118 (10) 3760-3769 2021/06/10
Publisher: WileyDOI: 10.1002/bit.27852
ISSN: 0006-3592
eISSN: 1097-0290
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Cell-encapsulated chitosan-collagen hydrogel hybrid nerve guidance conduit for peripheral nerve regeneration Peer-reviewed
Shun Itai, Karin Suzuki, Yuta Kurashina, Hiroo Kimura, Tsuyoshi Amemiya, Kazuki Sato, Masaya Nakamura, Hiroaki Onoe
Biomedical Microdevices 22 (4) 2020/12
Publisher: Springer Science and Business Media LLCDOI: 10.1007/s10544-020-00536-x
ISSN: 1387-2176
eISSN: 1572-8781
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ECM-based microfluidic gradient generator for tunable surface environment by interstitial flow Peer-reviewed
Azusa Shimizu, Wei Huang Goh, Shun Itai, Rahul Karyappa, Michinao Hashimoto, Hiroaki Onoe
Biomicrofluidics 14 (4) 044106-044106 2020/07/16
Publisher: AIP PublishingDOI: 10.1063/5.0010941
eISSN: 1932-1058
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ECM-based microchannel for culturing in vitro vascular tissues with simultaneous perfusion and stretch Peer-reviewed
Azusa Shimizu, Wei Huang Goh, Shun Itai, Michinao Hashimoto, Shigenori Miura, Hiroaki Onoe
Lab on a Chip 20 (11) 1917-1927 2020/04/20
Publisher: Royal Society of Chemistry (RSC)DOI: 10.1039/d0lc00254b
ISSN: 1473-0197
eISSN: 1473-0189
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Wireless and battery-free digestible sensor for intestinal bacteria monitoring
Ayaka Inami, Erika Iyama, Shun Itai, Hiroaki Onoe
MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences 575-576 2020
Publisher: Chemical and Biological Microsystems Society -
Double-layer collagen microtube for perfusable heterogeneous culture
Shun Itai, Hiroaki Onoe
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 1137-1138 2020
Publisher: Chemical and Biological Microsystems Society -
Stretching motion-driven ECM-based pulsatile flow generator for mimicking venous blood flow in vivo
Azusa Shimizu, Wei Huang Goh, Shun Itai, Michinao Hashimoto, Sigenori Miura, Hiroaki Onoe
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 314-315 2019
Publisher: Chemical and Biological Microsystems Society -
Cell-encapsulating chitosan-collagen hybrid hydrogel conduit for peripheral nerve regeneration
Shun Itai, Karin Suzuki, Yuta Kurashina, Hiroo Kimura, Tsuyoshi Amemiya, Kazuki Sato, Masaya Nakamura, Hiroaki Onoe
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 880-881 2019
Publisher: Chemical and Biological Microsystems Society -
Thin Layered Heterogeneous Vascularized 3D Tissue Models Constructed with Separated-Layer Collagen Microtube
Shun Itai, Hiroaki Onoe
Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) 2019- 118-119 2019/01/01
Publisher: Institute of Electrical and Electronics Engineers Inc.DOI: 10.1109/MEMSYS.2019.8870866
ISSN: 1084-6999
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Double-layer perfusable collagen microtube device for heterogeneous cell culture Peer-reviewed
Shun Itai, Hisatsugu Tajima, Hiroaki Onoe
Biofabrication 11 (1) 015010-015010 2018/11/30
Publisher: IOP PublishingeISSN: 1758-5090
Books and Other Publications 1
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ケミカルエンジニアリング バイオテクノロジーが拓く新時代
板井駿, 尾上弘晃
化学工業社 2018/11
Presentations 22
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In vitro Tube-shaped Intestinal Model with a Crypt-like Inner Surface Created by Electrolytic Microbubbles
Shuma Tanaka, Shun Itai, Hiroaki Onoe
The 10th International Conference on BioSensors, BioElectronics, BioMedical Devices, BioMEMS/NEMS & Applications (Bio4Apps 2024)
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An iPSC-blood vessel with spirally oriented smooth muscle mimic aging phenotypes in physiological function and metabolites
S. Itai, T. Toyohara, H. Onoe, T. Abe
The 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2024) 2024/10/15
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3D perfusable in vitro intestinal tube-shaped device with cryptic structure covered by mucin layer for bacterial co-culture
S. Uramoto, S. Tanaka, S. Itai, H. Onoe
The 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2024) 2024/10/15
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Mucin-layer-secreting in vitro intestinal tube-shaped device with crypt structure for bacterial co-culture
Shota Uramoto, Shuma Tanaka, Shun Itai, Hiroaki Onoe
The 37th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2024)
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Real-Time Assessment of Maturity by Microfiber Shaped Ipscs-Derived Cardiac Tissue
Akari Masuda, Shun Itai, Yuta Kurashina, Shugo Tohyama, Hiroaki Onoe
The 22nd International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2023)
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An engineered human iPSC-blood vessel with organized spiral oriented smooth muscle layers as a new functional model for cardiovascular diseases
Shun Itai, Mayuko Korekata, Takafumi Toyohara, Hiroaki Onoe, Takaaki Abe
International society for stem cell research (ISSCR) annual meeting 2023
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Oil-Sealed Rgd-Modified Hydrogel Microwell Array with Size-Selective Permeation for Analysis on Exosomes from Single Cells
Chisaki Yamagata, Shun Itai, Yuta Kurashina, Makoto Asai, Ayuko Hoshino, Hiroaki Onoe
The 36th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2023)
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Controlling Firing Point of Microfiber-Shaped Hipsc-Derived Cardiac Tissue with Localized Electrical Stimulation Device
Akari Masuda, Shun Itai, Yuta Kurashina, Shugo Tohyama, Hiroaki Onoe
The 36th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2023)
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A THREE-DIMENSIONAL ARTIFICIAL INTESTINAL TUBE WITH A CRYPT-LIKE INNER SURFACE
Shuma Tanaka, Shun Itai, Hiroaki Onoe
The 36th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2023)
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UNIDIRECTIONAL ANALYSIS OF CARDIAC PROPAGATION VELOCITY BY HUMAN IPSC-DERIVED CARDIAC CORE-SHELL MICROFIBER
Akari Masuda, Shun Itai, Yuta Kurashina, Shugo Tohyama, Hiroaki Onoe
The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2022)
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OIL-SEALED HYDROGEL MICROWELL ARRAY FOR ANALYSIS ON SECRETORY COMPONENTS FROM CONFINED SINGLE CELLS
Chisaki Yamagata, Shun Itai, Yuta Kurashina, Makoto Asai, Ayuko Hoshino, Hiroaki Onoe
The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2022)
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A THREE-DIMENSIONAL ARTIFICIAL INTESTINAL TUBE WITH A CRYPT-LIKE INNER SURFACE FORMED BY ELECTROLYTIC MICROBUBBLES
Shuma Tanaka, Shun Itai, Hiroaki Onoe
The 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2022) 2022/10/25
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Fixation-free evaluation of cardiac contractile force by human iPSC-derived cardiac core-shell microfiber
Akari Masuda, Keisuke Fukada, Shun Itai, Yuta Kurashina, Shuichi Akizuki, Shugo Tohyama, Jun Fujita, Hiroaki Onoe
The 35th International Conference on Micro Electro Mechanical Systems (MEMS 2022) 2022/01/12
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Tube-shaped in-vitro intestinal gut model with 3D isotropic medium supply for bacterial symbiosis
Mitsuki Kawahara, Shun Itai, Hiroaki Onoe
The 35th International Conference on Micro Electro Mechanical Systems (MEMS 2022) 2022/01/12
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In vitro artery model with circumferentially aligned & contractible smooth muscle by unfixed molding & screwing fabrication
Shun Itai, Hiroaki Onoe
The 35th International Conference on Micro Electro Mechanical Systems (MEMS 2022) 2022/01/12
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GLUCOSE-MONITORING JANUS HYDROGEL MICROBEADS WITH COMPENSATION FUNCIONS FOR SURROUNDING PH ENVIRONMENT
Maru Ando, Mio Tsuchiya, Shun Itai, Yun Jung Heo, Hiroaki Onoe
The 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (microTAS 2021)
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Endothelial chemical reaction and drug test reproduced on molded flexible collagen hydrogel tube
Shun Itai, Hiroaki Onoe
The 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2021) 2021/06/23
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Wireless and battery-free digestible sensor for intestinal bacteria monitoring
Ayaka Inami, Erika Iyama, Shun Itai, Hiroaki Onoe
The 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicorTAS 2020) 2020/10/05
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Stretching motion-driven ECM-based pulsatile flow generator for mimicking venous blood flow in vivo
Azusa Shimizu, Wei Huang Goh, Shun Itai, Michinao Hashimoto, Shigenori Miura, Hiroaki Onoe
The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicorTAS 2019) 2019/10/29
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Cell-encapsulating chitosan-collagen hybrid hydrogel conduit for peripheral nerve regeneration
Shun Itai, Karin Suzuki, Yuta Kurashina, Hiroo Kimura, Tsuyoshi Amemiya, Kazuki Sato, Masaya Nakamura, Hiroaki Onoe
The 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicorTAS 2019) 2019/10/29
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Thin layered heterogeneous vascularized 3D tissue models constructed with separated-layer collagen microtube
Shun Itai, Hiroaki Onoe
The 32nd International Conference on Micro Electro Mechanical Systems (MEMS 2019) 2019/01/29
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Double-layer collagen microtube for perfusable heterogeneous culture
Shun Itai, Hiroaki Onoe
The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicorTAS 2017) 2017/10/23
Industrial Property Rights 7
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多層構造体とその製造方法及び利用方法
板井駿, 尾上弘晃
特許7165330
Property Type: Patent
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管腔構造体,及び管腔構造体の製造方法
尾上弘晃, 田中秀磨, 板井駿, 豊原敬文
Property Type: Patent
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神経再生を促進するための管状構造体
尾上弘晃, 鈴木果林, 板井駿, 倉科佑太, 木村洋朗, 雨宮剛, 佐藤和毅, 中村雅也
Property Type: Patent
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分岐人工血管モデルの製造方法
板井駿, 是方真悠子, 豊原敬文, 尾上弘晃
Property Type: Patent
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幹細胞を用いた人工組織チューブ及びその製造方法
板井駿, 豊原敬文
Property Type: Patent
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人工組織チューブ及びその製造方法
尾上弘晃, 板井駿
Property Type: Patent
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マイクロウェルアレイ,その製造方法,及び単一細胞由来エクソソームの解析方法
尾上弘晃, 山形智咲, 板井駿, 倉科佑太, 星野歩子
Property Type: Patent
Research Projects 9
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動脈硬化性腎動脈狭窄患者CT画像を基にした生理的に収縮・弛緩可能なiPS由来人工分枝血管の開発による動脈硬化再現と病態解明
板井駿
Offer Organization: 武田科学振興財団
System: 医学系研究助成(基礎)
2025/07 - 2030/03
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「生きた」人工血管の社会実装
豊原敬文, 板井駿
Offer Organization: みちのくアカデミア発スタートアップ共創プラットフォーム(MASP)
System: みちのくGAPファンド(スタートアップ・エコシステム共創プログラム)
2025/04 - 2028/03
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自在に収縮・弛緩可能なiPSC人工老化血管モデルの構築による老化治療法研究
板井 駿
Offer Organization: 日本学術振興会
System: 科学研究費助成事業
Category: 若手研究
Institution: 東北大学
2023/04 - 2026/03
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iPS 細胞由来 3D 血管を用いた血管再生治療の開発と社会実装
豊原敬文, 板井駿
Offer Organization: 東北大学
System: ビジネス・インキュベ-ション・プログラム(BIP)
2024/04 - 2025/03
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細胞加工ゲルチューブを用いた腸・血管・リンパ共培養による腸内細菌共生人工腸の構築
板井 駿
Offer Organization: 日本学術振興会
System: 科学研究費助成事業 特別研究員奨励費
Category: 特別研究員奨励費
Institution: 東北大学
2022/04 - 2025/03
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血管老化治療法開発に向けた自在変形人工血管モデルの開発
板井駿
Offer Organization: 公益財団法人 テルモ生命科学振興財団
System: 研究開発助成金
Category: ⑤予防医療研究
Institution: 東北大学
2023/01 - 2024/03
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多段階ゲル型内組織成熟モールディング法(GG-3M 法)による大血管組織モデル構築
板井駿
Offer Organization: 慶應義塾大学
System: 潮田記念基金による慶應義塾博士課程学生研究支援プログラム
Institution: 慶應義塾大学
2021/04 - 2022/03
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アトピー性皮膚炎の炎症再現が可能なin vitro皮膚組織モデルの構築
板井 駿
Offer Organization: 日本学術振興会
System: 科学研究費助成事業 特別研究員奨励費
Category: 特別研究員奨励費
Institution: 慶應義塾大学
2020/04 - 2022/03
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灌流共培養可能なコラーゲンチューブを用いたin vitro 皮膚炎組織モデル構築
板井駿
Offer Organization: 慶應義塾大学
System: 潮田記念基金による慶應義塾博士課程学生研究支援プログラム
Institution: 慶應義塾大学
2019/04 - 2020/03