Details of the Researcher
Research History 4
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2020/04 - 2023/03Nagoya University Institute for Advanced Research Specially Appointed Assistant Professor
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2024/04 - PresentTohoku University Frontier Research Institute for Interdisciplinary Sciences Creative Interdisciplinary Research Division Assistant Professor
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2018/04 - 2020/03Monterey Bay Aquarium Research Institute Research and Development Postdoctoral fellow
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2017/09 - 2018/03Chubu University College of Bioscience and Biotechnology researcher
Education 1
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Nagoya University Graduate School of Bioagricultural Sciences
2014/04 - 2017/03
Committee Memberships 3
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日本進化学会 男女共同参画担当
2024/08 - Present
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日本動物学会 第96回 名古屋大会 2025 実行委員会
2025/01 - 2025/09
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The Rising Generation of Evo-Devo Biologists Organizing committee member of
2014 - 2017
Research Interests 7
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Luciferin
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Ctenophora
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Octocorallia
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kleptoprotein
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Parapriacanthus ransonneti
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Bioluminescence
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Evolution
Research Areas 1
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Life sciences / Evolutionary biology / Bioluminescence
Awards 3
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Research Encouragement Award
2023/07 Society of Evolutionary Studies, Japan
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日本進化学会第24回大会口頭発表優秀賞
2022/08 日本進化学会 ナマコ類における生物発光の分布と進化
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学術 ・みらい助成
2020/12 公益財団法人中部科学技術センター 盗タンパク質の取込み機構の解明:発光魚:キンメモドキが発光酵素を取込む分子機構の解明
Papers 19
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Evidence for de novo Biosynthesis of the Luminous Substrate Coelenterazine in Ctenophores International-journal International-coauthorship Peer-reviewed
Manabu Bessho-Uehara, Wentao Huang, Wyatt L. Patry, William E. Browne, Jing-Ke Weng, Steven H.D. Haddock
iScience 23 (12) 101859-101859 2020/12
Publisher: Elsevier BVDOI: 10.1016/j.isci.2020.101859
ISSN: 2589-0042
eISSN: 2589-0042
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Biochemical characterization of diverse deep-sea anthozoan bioluminescence systems International-journal International-coauthorship Peer-reviewed
Manabu Bessho-Uehara, Warren R. Francis, Steven H. D. Haddock
Marine Biology 167 (8) 2020/08
Publisher: Springer Science and Business Media LLCDOI: 10.1007/s00227-020-03706-w
ISSN: 0025-3162
eISSN: 1432-1793
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Kleptoprotein bioluminescence: Parapriacanthus fish obtain luciferase from ostracod prey Peer-reviewed
Manabu Bessho-Uehara, Naoyuki Yamamoto, Shuji Shigenobu, Hitoshi Mori, Keiko Kuwata, Yuichi Oba
Science Advances 6 (2) eaax4942-eaax4942 2020/01
ISSN: 2375-2548
eISSN: 2375-2548
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Firefly genomes illuminate parallel origins of bioluminescence in beetles International-journal International-coauthorship Peer-reviewed
Timothy R. Fallon, Sarah E. Lower, Ching-Ho Chang, Manabu Bessho-Uehara, Gavin J. Martin, Adam J. Bewick, Megan Behringer, Humberto J. Debat, Isaac Wong, John C. Day, Anton Suvorov, Christian J. Silva, Kathrin F. Stanger-Hall, David W. Hall, Robert J. Schmitz, David R. Nelson, Sara M. Lewis, Shuji Shigenobu, Seth M. Bybee, Amanda M. Larracuente, Yuichi Oba, Jing-Ke Weng
ELIFE 7 2018/10
DOI: 10.7554/elife.36495
ISSN: 2050-084X
eISSN: 2050-084X
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Development of venus-fused Cypridina luciferase (VCL) and specific nanobody-tethering assay to model kleptoprotein uptake
Risa Aoki, Akiko Nakanishi, Hotaka Atarashi, Kanchi Nanjo, Masahiko Hibi, Manabu Bessho-Uehara
Photochemical & Photobiological Sciences 2026/07
DOI: 10.1007/s43630-026-00922-z
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Absence of the luciferase gene in the genome of the kleptoprotein bioluminescent fish Parapriacanthus ransonneti Peer-reviewed
Manabu Bessho-Uehara, Katsushi Yamaguchi, Keita Koeda, Shohei Matsuzaki, Taro Maeda, Shuji Shigenobu
Scientific Reports 2026/04/01
DOI: 10.1038/s41598-026-43942-6
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Glow in the D-ARK: a new bioluminescent species of Corallizoanthus (Anthozoa: Zoantharia: Parazoanthidae) from southern Japan Peer-reviewed
Hiroki Kise, Manabu Bessho-Uehara, Kenta C. F. Kondo, Kiko Shimoji, Shohei Ito, Shinji Tsuchida, Yoshihiro Fujiwara, James D. Reimer
Royal Society Open Science 2025/11
DOI: 10.1098/rsos.250890
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A bioluminescent deep-sea polychaete within the genus Aricidea (Paraonidae) from Minamidaito Island, Japan Peer-reviewed
Manabu Bessho-Uehara, Naoto Jimi, Yoshihiro Fujiwara
Scientific Reports 2025/10/21
DOI: 10.1038/s41598-025-20544-2
ISSN: 2045-2322
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Biochemical basis of endogenous bioluminescent springtail Lobella sauteri (Collembola) Peer-reviewed
Manabu Bessho-Uehara, Takumi Kato, Atsuko Ohira, Taizo Nakamori, Yuichi Oba
Biology Open 2025/05/15
DOI: 10.1242/bio.061829
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A review of the genus Pempheris (Teleostei, Pempheridae) found in Japan and Taiwan Peer-reviewed
Keita Koeda, Manabu Bessho-Uehara
ZooKeys 2024/12/09
DOI: 10.3897/zookeys.1220.126762
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Evolution of bioluminescence in Anthozoa with emphasis on Octocorallia Peer-reviewed
Danielle M. DeLeo, Manabu Bessho-Uehara, Steven H.D. Haddock, Catherine S. McFadden, Andrea M. Quattrini
Proceedings of the Royal Society B: Biological Sciences 291 (2021) 2024/04/24
ISSN: 0962-8452
eISSN: 1471-2954
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Contribution to the taxonomy of Lobellini (Collembola: Neanurinae) and investigations on luminous Collembola from Japan Peer-reviewed
ATSUKO OHIRA, TAIZO NAKAMORI, SACHI MATSUMOTO, MANABU BESSHO-UEHARA, TAKUMI KATO, YUICHI OBA
Zootaxa 5325 (1) 63-89 2023/08/07
Publisher: Magnolia PressDOI: 10.11646/zootaxa.5325.1.4
ISSN: 1175-5326
eISSN: 1175-5334
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Investigating the diversity of bioluminescent marine worm Polycirrus (Annelida), with description of three new species from the Western Pacific Peer-reviewed
Naoto Jimi, Manabu Bessho-Uehara, Koji Nakamura, Masahiko Sakata, Taro Hayashi, Shusei Kanie, Yasuo Mitani, Yoshihiro Ohmiya, Aoi Tsuyuki, Yuzo Ota, Sau Pinn Woo, Katsunori Ogoh
Royal Society Open Science 10 (3) 2023/03
DOI: 10.1098/rsos.230039
eISSN: 2054-5703
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Glowing sea cucumbers: Bioluminescence in the Holothuroidea Invited Peer-reviewed
Manabu Bessho-Uehara, Jérôme Mallefet, Steven H.D. Haddock
The World of Sea Cucumbers: Challenges, Advances, and Innovations 361-375 2023/01/01
DOI: 10.1016/B978-0-323-95377-1.00003-5
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14-3-3 proteins are luciferases candidate proteins from lanternfish Diaphus watasei. International-journal Peer-reviewed
Daichi Yano, Manabu Bessho-Uehara, José Paitio, Masakazu Iwasaka, Yuichi Oba
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 22 (2) 263-277 2022/10/05
DOI: 10.1007/s43630-022-00311-2
ISSN: 1474-905X
eISSN: 1474-9092
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Acquisition of bioluminescent trait by non-luminous organisms from luminous organisms through various origins Peer-reviewed
Chatragadda Ramesh, Manabu Bessho-Uehara
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES 20 (11) 1547-1562 2021/10
DOI: 10.1007/s43630-021-00124-9
ISSN: 1474-905X
eISSN: 1474-9092
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Identification and characterization of the Luc2-type luciferase in the Japanese firefly, Luciola parvula, involved in a dim luminescence in immobile stages Peer-reviewed
Manabu Bessho-Uehara, Yuichi Oba
LUMINESCENCE 32 (6) 924-931 2017/09
DOI: 10.1002/bio.3273
ISSN: 1522-7235
eISSN: 1522-7243
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Biochemical characteristics and gene expression profiles of two paralogous luciferases from the Japanese firefly Pyrocoelia atripennis (Coleoptera, Lampyridae, Lampyrinae): insight into the evolution of firefly luciferase genes Peer-reviewed
Manabu Bessho-Uehara, Kaori Konishi, Yuichi Oba
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES 16 (8) 1301-1310 2017/08
DOI: 10.1039/c7pp00110j
ISSN: 1474-905X
eISSN: 1474-9092
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Bioluminescence of a firefly pupa: involvement of a luciferase isotype in the dim glow of pupae and eggs in the Japanese firefly, Luciola lateralis. International-journal Peer-reviewed
Yuichi Oba, Mana Furuhashi, Manabu Bessho, Shingo Sagawa, Haruyoshi Ikeya, Satoshi Inouye
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 12 (5) 854-63 2013/05
DOI: 10.1039/c3pp25363e
ISSN: 1474-905X
eISSN: 1474-9092
Misc. 2
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Luciferase isotype involving in the dim glow of pupae and eggs in the Japanese firefly, Luciola lateralis
Yuichi Oba, Mana Furuhashi, Manabu Bessho, Shingo Sagawa, Haruyoshi Ikeya, Satoshi Inouye
LUMINESCENCE 29 38-38 2014/08
ISSN: 1522-7235
eISSN: 1522-7243
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Purification of a Novel Luciferase from Luminous Fish, Parapriacanthus ransonneti
Manabu Bessho, Yuichi Oba
LUMINESCENCE 29 63-63 2014/08
ISSN: 1522-7235
eISSN: 1522-7243
Books and Other Publications 10
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水の中の小さな美しい生き物たち : 小型ベントス・プランクトン百科 : カラー図解
仲村, 康秀, 山崎, 博史, 多様性生物学, 田中, 隼人, 日本プランクトン学会
朝倉書店 2025/08
ISBN: 9784254171952
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教えて!クラゲのほんと : 世界一のクラゲ水族館が答える100の質問
鶴岡市立加茂水族館
緑書房 2024/11
ISBN: 9784868110088
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研究者、生活を語る──「両立」の舞台裏
岩波書店編集部
岩波書店 2024/10/21
ISBN: 4000616617
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On the Luminous Organisms
2024/09/13
ISBN: 9784254171921
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なぜ海は光る生物で溢れているのか?――食物網によるルシフェリン分配の化学生態と進化
別所上原学
2023/05
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職業冒険者としての研究者
別所上原学
2023/03
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研究者,生活を語る(3)おさるのジョージと黄色い帽子のおじさんのような生活
別所-上原 学
2023/03
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他者のタンパク質を利用する盗タンパク質現象
加藤巧己, 別所-上原 学
2023
DOI: 10.34565/seibutsukogaku.101.4_200
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PlotsOfData - 箱ひげ図やバイオリンプロット, jitterプロットが簡単に描けるウェブツール
別所上原学
2022/10
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研究者の結婚生活: 恋愛はぜんぜん科学的じゃない⁉
高山善光
日本の研究者出版 2020/10
Presentations 38
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太古より受け継がれる深海サンゴの発光 Invited
別所-上原 学
新妻免疫塾 (YouTubeチャンネル) 2020/06/22
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Kleptoprotein Bioluminescence Invited
Manabu Bessho-Uehara
Yosakoi Ecology Seminar 2020/06/16
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Origin of Bioluminescence in the sea Invited
Manabu Bessho-Uehara
2025/10/18
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海洋発光生物の話 International-presentation Invited
別所-上原学
名古屋大学博物館 第 33 回特別展 発光生物 裏庭から深海まで -光を操る生き物たち 講演会 2025/09/20
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Kleptoprotein Bioluminescence: A fish steals the light from its prey International-presentation Invited
Manabu Bessho-Uehara
The 12th Indo-Pacific Fish Conference (IPFC12) 2025/07/15
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ザウテルアカイボトビムシの生物発光機構に関する研究 〜新規の発光メカニズムと脱皮に伴う発光強度の変化について〜
別所-上原, 学, 加藤 巧己, 大平 敦子, 中森 泰三, 大場 裕一
土壌動物学会 2025/06/01
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深海の暗黒に溢れる生物の光ー生態と進化の理解に向けて Invited
別所-上原学
第13回海中海底工学フォーラム・ZERO 2025/04/10
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Kleptoprotein bioluminescence Invited
Manabu BESSHO-Uehara
The 2nd NIBB Workshop on Kleptobiology 2024/09/16
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Kleptoprotein bioluminescence in golden sweeper Parapriacanthus ransonneti Invited
Manabu Bessho-Uehara
2024/09/13
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Kleptoprotein: Leaps in the Evolution Invited
Manabu Bessho-Uehara
2024/07/11
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キンメモドキの盗タンパク質現象とタンパク質取込メカニズム解明に向けて
別所上原学
2023年度日本動物学会中部支部大会 2023/12/01
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オンラインツール PlotsOfData による箱ひげ図の作成 Invited
別所-上原 学
AJACSオンライン18「オンラインで使える統計解析ツールを知って・学んで・使う」 2023/11/16
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ナマコ綱における発光の報告と祖先形質推定
別所-上原 学, Jérôme Mallefe, Steven H.D. Haddock
生物発光化学発光研究会 第38回学術講演会 2023/11/11
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Biochemical characterization of photoproteins in Pelagia.
Manabu Bessho-Uehara
2023/09/18
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Marine invertebrates as a frontier of bioluminescence research Invited
2023/09/08
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Kleptoprotein: sequestering functional protein from prey for bioluminescence. Invited
Manabu Bessho-Uehara
OIST Seminar 2023/09/04
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Seek of a new luminous animal possessing kleptoprotein
2023/09/01
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目がないのに光る生き物たち Invited
別所上原学
名古屋大学協力講座 動物の世界を覗く 2023/08/18
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leptoprotein: sequestering functional protein from prey for bioluminescence. Invited
Manabu Bessho-Uehara
RIKEN BDR Open Seminar 2023/08/09
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ウミホタルから光を盗むキンメモドキ 新しい進化の戦略 ― 盗タンパク質 Invited
別所上原学
葛西臨海水族園 高校生大学生向け講座 海の学び舎2023 2023/07/21
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深海に棲む光る生物のいろいろ Invited
別所上原学
日本動物学会関東支部公開講演会 2023/07/19
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Kleptoprotein ~ Evolution not written in the genome ~ Invited
2023/05/19
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海の光の素の話 Invited
別所上原学
ACT-X「生命と化学」× さきがけ「未来材料」 = 『化学未来生命材料』 2022/12/27
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海洋発光生物の多様性と進化:キンメモドキ、クシクラゲ、サンゴ、ナマコを例に Invited
別所上原学
下田セミナー 2022/12/01
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盗タンパク質による生物発光 Invited
別所上原学
ERATO共生進化機構先端セミナー 2022/10/15
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ナマコ類における生物発光の分類と進化
別所上原学
日本動物学会第93回大会 2022/09/03
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ナマコ類における生物発光の分布と進化
別所上原学
日本進化学会第24回沼津大会 2022/08/04
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ナマコ類における生物発光の多様性 Invited
別所上原学
第67回瀬戸海洋生物学セミナー 2022/07/26
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餌生物の能力をコピー!?キンメモドキの「盗タンパク質」 Invited
別所上原学
静岡ライフサイエンスシンポジウム 2022/03/06
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名古屋大学出前授業2 太古の海の光る森 Invited
別所-上原 学
豊橋市自然史博物館 ワークショップ・講演会・解説会 2021/11/20
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盗タンパク質による生物発光:ウミホタルを食べて光るキンメモドキ Invited
別所上原学
基礎生物学研究所 部門公開セミナー 2021/11/17
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Kleptoprotein Bioluminescence: A fish obtains luciferase from a luminous ostracod prey
Manabu Bessho-Uehara, Naoyuki Yamamoto, Shuji Shigenobu, Keiko Kuwata, Yuichi Oba
Living Light 2021/09/23
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Biochemical characterization of diverse deep‐sea anthozoan bioluminescence systems
Manabu Bessho-Uehara, Warren R. Francis, Steven H.D. Haddock
16th Deep-sea Biology Symposium 2021/09/15
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深海サンゴ(花虫綱)の生物発光メカニズムの比較と進化
別所-上原 学
第23回進化学会 2021/08/19
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Kleptoprotein Bioluminescence: Protein uptake in a fish from luminous crustacean
Manabu Bessho-Uehara, Shuji Shigenobu, Keiko Kuwata, Naoyuki Yamamoto, Yuichi Oba
2nd AsiaEvo Conference 2021/08/17
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ウミホタルを食べて光る魚 〜盗タンパク質による生物発光〜 Invited
別所-上原 学
ScienceOme 2021/08/04
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生物発光の収斂進化 Invited
別所-上原 学
永井研公開セミナー 2020/06/21
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Evolution of bioluminescence in the sea Invited
Manabu Bessho-Uehra
Moss Landing Marine Laboratories Seminar 2020/02/20
Research Projects 7
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Discovery of Bioluminescent organisms with Kleptoprotein
2022 - 2028
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発光基質セレンテラジンの生合成酵素の解明
大場 裕一, 小沼 健, 加藤 太一郎, 別所 学
Offer Organization: 日本学術振興会
System: 科学研究費助成事業
Category: 基盤研究(C)
Institution: 中部大学
2024/04/01 - 2027/03/31
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Taxonomical review of Pempheridae and the origin and evolution of bioluminescence
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Category: Grant-in-Aid for Scientific Research (C)
Institution: Kuroshio Biological Research Foundation
2021/04/01 - 2025/03/31
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Kleptoprotein bioluminescence in fish: Molecular mechanism of protein uptake and its evolutionary origin
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists
Category: Grant-in-Aid for Early-Career Scientists
Institution: Nagoya University
2021/04 - 2025/03
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Discovery of the second kleptoprotein
Offer Organization: Japan Science and Technology Agency
2021/10 - 2024/03
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Molecular mechanism involved in the uptake of ostracod luciferase into luminous fish Parapriacanthus
Bessho-Uehara Manabu
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up
Category: Grant-in-Aid for Research Activity Start-up
Institution: Nagoya University
2020/09 - 2022/03
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ウミホタルを食べて光る魚-キンメモドキの発光メカニズムの解明-
別所 学
Offer Organization: 日本学術振興会
System: 科学研究費助成事業 特別研究員奨励費
Category: 特別研究員奨励費
Institution: 名古屋大学
2015/04/24 - 2017/03/31
Media Coverage 10
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How a fish steals its ability to glow
The New York Times
2020/01/09
Type: Internet
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From glowing corals to vomiting shrimp, animals have used bioluminescence to communicate for millions of years – here’s what scientists still don’t know about it
the Conversation the Conversation
2024/06/14
Type: Internet
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光るサンゴ 起源は5億4千万年前 最古の発光生物に
朝日新聞 朝日新聞 朝19
2024/05/03
Type: Newspaper, magazine
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最古の光る生物は5億4000万年前の深海サンゴ、約2億年記録更新
ナショナル ジオグラフィック ナショナル ジオグラフィック
2024/05/02
Type: Newspaper, magazine
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In Coral Fossils, Searching for the First Glow of Bioluminescence
The New York Times The New York Times https://www.nytimes.com/2024/04/23/science/bioluminescence-evolution-sea-creatures.html
2024/05
Type: Internet
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跳躍的進化のカギ!?生物の“盗み”戦略
NHK サイエンスZERO
2023/07
Type: TV or radio program
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【くもM LAB】発光生物に恋してる!?生き物の光に魅了された研究者(名古屋大学高等研究院特任助教 別所上原学先生 インタビュー
SienceTalks 【くもM LAB】
2021/09
Type: Internet
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海の光るいのち、進化をひも解く/別所-上原学特任助教
名古屋大学産学官連隊推進本部 「名大研究フロントライン」
2021/07
Type: Internet
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深海発光サンゴ 新たに4種
中日新聞社 中日新聞
2020/10/22
Type: Newspaper, magazine
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Fish Steals Bioluminescence from Prey
The Scientist
2020/01/09
Type: Internet
Other 1
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Glow-in-the-dark corals light up the deep sea
https://orcid.org/0000-0002-7388-464X