Details of the Researcher

PHOTO

Naru Shiraishi
Section
Tohoku University Hospital
Job title
Senior Assistant Professor
Degree
  • 博士(歯学)(東北大学)

e-Rad No.
60585355

Research Areas 2

  • Life sciences / Oral medicine /

  • Life sciences / Prosthodontics /

Papers 47

  1. 筋萎縮性側索硬化症患者に対する舌接触補助床の効果の検討

    互野 亮, 白石 成, 江草 宏, 小山 重人

    Japanese Journal of Maxillo Facial Implants 23 (3) 223-223 2024/11

    Publisher: (公社)日本顎顔面インプラント学会

    ISSN: 1347-894X

    eISSN: 2433-5509

  2. 上顎骨切除後に皮弁再建と広範囲顎骨支持型装置・補綴で対応した1症例

    佐藤 奈央子, 互野 亮, 森島 浩允, 畠山 高徳, 小坂 萌, 白石 成, 山内 健介, 依田 信裕, 小山 重人

    Japanese Journal of Maxillo Facial Implants 23 (3) 229-229 2024/11

    Publisher: (公社)日本顎顔面インプラント学会

    ISSN: 1347-894X

    eISSN: 2433-5509

  3. Activities of the dorsolateral and medial prefrontal cortices during oral function training with cognitive training elements: a NIRS study

    Masumi Abe, Rui Nouchi, Toru Ogawa, Naru Shiraishi, Hiroki Hihara, Keiichi Sasaki, Nobuhiro Yoda

    BMC Oral Health 24 (1) 2024/10/19

    Publisher: Springer Science and Business Media LLC

    DOI: 10.1186/s12903-024-05044-5  

    eISSN: 1472-6831

  4. 口腔機能低下症患者に対する新規パルス磁気刺激装置の舌骨挙上への影響に関する研究

    砂田 慶一, 白石 成, 畠山 高徳, 日原 大貴, 小川 徹, 佐々木 啓一, 依田 信裕

    日本補綴歯科学会誌 16 (東北・北海道支部学術大会特別号) 36-36 2024/10

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  5. 東北大学病院嚥下治療センター・歯科における筋萎縮性側索硬化症患者に対する介入の実態 舌接触補助床の適用について

    互野 亮, 白石 成, 千葉 智弘, 砂田 慶一, 小川 徹, 江草 宏, 小山 重人

    顎顔面補綴 47 (1) 14-20 2024/06

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  6. 東北大学病院嚥下治療センター・歯科における筋萎縮性側索硬化症患者に対する介入の実態 舌接触補助床の適用について

    互野 亮, 白石 成, 千葉 智弘, 砂田 慶一, 小川 徹, 江草 宏, 小山 重人

    顎顔面補綴 47 (1) 14-20 2024/06

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  7. 認知機能と口腔機能の相関に関する医師・歯科医師の意識調査 医科歯科連携ECCOプロジェクト

    笛木 賢治, 眞鍋 雄太, 佐々木 啓一, 橋本 衛, 木本 克彦, 石川 智久, 上田 貴之, 内海 久美子, 釘宮 嘉浩, 白石 成, 安部 友佳, 稲用 友佳, 馬場 一美, 窪木 拓男, 池田 学

    老年精神医学雑誌 35 (3) 283-290 2024/03

    Publisher: (株)ワールドプランニング

    ISSN: 0915-6305

  8. 下顎骨エナメル上皮腫に対する反復処置法に顎補綴で対応した1症例

    畠山 高徳, 佐藤 奈央子, 互野 亮, 泉田 一賢, 小坂 萌, 白石 成, 山内 健介, 小山 重人

    顎顔面補綴 46 (2) 53-53 2023/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  9. 東北大学病院嚥下治療センター・歯科における筋萎縮性側索硬化症(ALS)患者に対する介入の実態 ALSの重症度と口腔機能の関連

    互野 亮, 白石 成, 千葉 智弘, 砂田 慶一, 小川 徹, 小山 重人

    顎顔面補綴 46 (2) 59-59 2023/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  10. 下顎歯肉癌の口腔顎顔面再建に顎補綴で対応した1症例

    佐藤 奈央子, 互野 亮, 森島 浩允, 畠山 高徳, 小坂 萌, 白石 成, 泉田 一賢, 山内 健介, 小山 重人

    顎顔面補綴 46 (2) 61-61 2023/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  11. Difference in the Electromyographic Behavior of the Masticatory and Swallowing Muscles During Cued Versus Spontaneous Swallowing

    Naoya Saito, Toru Ogawa, Naru Shiraishi, Rie Koide, Hideya Komine, Masayoshi Yokoyama, Soshi Hanawa, Keiichi Sasaki

    Dysphagia 39 (3) 398-406 2023/09/26

    Publisher: Springer Science and Business Media LLC

    DOI: 10.1007/s00455-023-10621-x  

    ISSN: 0179-051X

    eISSN: 1432-0460

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    Abstract The risk of dysphagia and/or aspiration is determined using screening tests, such as the repeated saliva swallowing test and modified water swallowing test, which evaluate cued swallowing. However, humans masticate and swallow foods with various consistencies, forms, and amounts, without conscious awareness. Therefore, this study aimed to examine the difference in the behavior of masticatory and swallowing muscles during spontaneous versus cued swallowing through a series of mastication and swallowing processes by evaluating surface electromyogram (sEMG) signals. The effect of the consistency and amount of food on the behavior of these muscles was also investigated. The sEMG recordings of the masseter muscles and anterior belly of the digastric muscle for 12 subjects, and genioglossus muscle for 5 subjects were obtained. The genioglossus activity was recorded using custom-made ball electrodes. The test foods were cookies and tofu, in amounts of 2 g and 4 g. The normalized muscle activity (integrated EMG), duration of the muscle activity, initial activation timepoint of each muscle, and total duration of swallowing were compared among four conditions. The activity of each muscle was significantly higher during the swallowing of cookies than tofu, for 4 g vs 2 g, and for cued versus spontaneous swallowing. The duration of each muscle activity, initial activation timepoint, and total duration of swallowing were significantly longer for cookies versus tofu, for 4 g vs 2 g, and for spontaneous versus cued swallowing. These results suggest that the behavior of the masticatory and swallowing muscles is affected by cued swallowing and by the consistency and amount of food.

  12. 東北大学病院嚥下治療センターにおける嚥下障害と口腔機能低下の関連性の検討

    白石 成, 互野 亮, 小宮山 貴将, 泉田 一賢, 西條 佳奈, 小川 徹, 小山 重人, 佐々木 啓一

    日本補綴歯科学会誌 15 (特別号) 292-292 2023/05

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  13. Introduction of integrated dental training jaw models and rubric criteria

    Taichi Tenkumo, Takeshi Fuji, Motohide Ikawa, Shigeru Shoji, Hiromi Sasazaki, Yoko Iwamatsu-Kobayashi, Yayoi Okuyama, Hiroyuki Matsui, Naru Shiraishi, Toshi Furuuchi, Keisuke Higuchi, Wataru Hashimoto, Yasuhisa Takeuchi, Hidetoshi Simauchi, Keiichi Sasaki

    European Journal of Dental Education 23 (1) e17-e31 2023/03

    DOI: 10.1111/eje.12395  

    ISSN: 1396-5883

    eISSN: 1600-0579

  14. Sensory neuromuscular electrical stimulation for dysphagia rehabilitation: A literature review Peer-reviewed

    Itt Assoratgoon, Naru Shiraishi, Ryo Tagaino, Toru Ogawa, Keiichi Sasaki

    Journal of Oral Rehabilitation 2023/02

    Publisher: Wiley

    DOI: 10.1111/joor.13391  

    ISSN: 0305-182X 1365-2842

    eISSN: 1365-2842

  15. Medical-Dental collaboration: Exploratory research project on the Correlation between Cognitive and Oral function (ECCO): background and research activity Peer-reviewed

    Kenji Fueki, Keiichi Sasaki, Yuta Manabe, Katsuhiko Kimoto, Takuo Kuboki, Takayuki Ueda, Yuka Abe, Yuka Inamochi, Yoshihiro Kugimiya, Naru Shiraishi, Takashi Saito, Takuya Kobayashi, Mamoru Hashimoto, Tomohisa Ishikawa, Kumiko Utsumi, Manabu Ikeda, Kazuyoshi Baba

    Annals of Japan Prosthodontic Society 15 (1) 72-78 2023/01

    Publisher: Japan Prosthodontic Society

    DOI: 10.2186/ajps.15.72  

    ISSN: 1883-4426

    eISSN: 1883-6860

  16. 舌がん患者の外科的治療術前・後における舌圧と口腔機能との関連

    互野 亮, 小山 重人, 白石 成, 泉田 一賢, 小宮山 貴将, 佐藤 奈央子, 小川 徹, 佐々木 啓一

    日本補綴歯科学会誌 14 (特別号) 284-284 2022/07

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  17. Changes in tongue pressure and dysphagia at oral cancer patients by palatal augmentation prosthesis International-journal Peer-reviewed

    Izumita Kuniyuki, Takuma Hisaoka, Ryoukichi Ikeda, Jun Suzuki, Naoko Sato, Ryo Tagaino, Tomonori Kambayashi, Ai Hirano‐Kawamoto, Jun Ohta, Akira Ohkoshi, Ryo Ishii, Naru Shitraishi, Kengo Kato, Shigeto Koyama, Keiichi Sasaki, Yukio Katori

    Cancer Reports 5 (7) e1516 2022/07

    Publisher: Wiley

    DOI: 10.1002/cnr2.1516  

    ISSN: 2573-8348

    eISSN: 2573-8348

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    BACKGROUND: The palatal augmentation prosthesis (PAP) is an intraoral prosthesis used in the treatment of dysphagia. AIM: The objective of the study is to examine the effect of PAP using tongue pressure and the Videofluoroscopic Dysphagia Scale (VDS) to understand the precise mechanism for improvement in swallowing function with PAP for oral cancer at retrospective survey. METHODS AND RESULTS: Fifteen patients were provided PAPs. Tongue pressure and VDS were evaluated with and without PAP. After intervention with PAP, tongue pressure significantly increased as compared to when without PAP (p < .05). The total mean VDS score with PAP was found to have significantly improved (p < .05). The mean VDS score of the oral phase also significantly improved with the PAP compared to without the PAP group (p < .05). Significant differences (p < .01) were found in each category, such as tongue to palate contact and pyriform sinus residue. CONCLUSION: PAP can improve tongue pressure, tongue to palate contact, and pyriform sinus residue.

  18. Medical-Dental Collaboration and Interprofessional Training for Maxillofacial Diseases at Tohoku University Hospital.

    Shigeto Koyama, Kuniyuki Izumita, Naoko Sato, Ryo Tagaino, Takanori Hatakeyama, Naru Shiraishi, Nobuhiro Yoda, Kaoru Igarashi, Tetsu Takahashi, Keiichi Sasaki

    The Tohoku journal of experimental medicine 256 (3) 225-234 2022/03

    DOI: 10.1620/tjem.256.225  

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    The Tohoku University Hospital has been a clinical and research facility for all the related departments of Tohoku University. Medical-dental and interprofessional collaboration has resulted in special treatment teams, made up of members of departments such as the center for head and neck cancer, the center for dysphagia, and the cleft lip and palate center. Those treatment teams held conferences, case study meetings, reading sessions, and in-hospital seminars. The purpose of this study was to evaluate the outcomes of various medical-dental and the interprofessional collaboration at Tohoku University Hospital and training program to equip hospital dentists in higher medical institutions. The attainment targets are the acquisition of basic medical skills and knowledge under the guidance of supervising doctors. As a result, the hospital dentists could acquire their own specialized knowledge and skills certificated by each academic society. The smooth team treatment has been achieved, and the number of cases discussed by cancer boards and center for dysphagia has increased year by year due to the efficiency of their clinical pathways. On the dental care side as well, the wearing rates of maxillofacial prosthetic devices such as maxillofacial prostheses and palatal augmentation prostheses (PAP) have improved, which have contributed to improving patient's stomatognathic function. Tohoku University Hospital has been practicing collaboration between medical and dental professionals and it has produced mutual benefits. Our interprofessional training system based on the medical-dental collaboration could develop professionals who have acquired cross-disciplinary knowledge and skills from experienced doctors.

  19. A case report of improving cosmetics and masticatory function after maxillectomy for gingival carcinoma by maxillary prosthetic treatment Peer-reviewed

    Naru Shiraishi

    Annals of Japan Prosthodontic Society 14 (2) 181-184 2022

    Publisher: Japan Prosthodontic Society

    DOI: 10.2186/ajps.14.181  

    ISSN: 1883-4426

    eISSN: 1883-6860

  20. オクルーザルスプリントの使用により下顎偏位の改善を見た下顎骨片側離断後の再建症例

    互野 亮, 佐藤 奈央子, 泉田 一賢, 畠山 高徳, 白石 成, 小坂 萌, 依田 信裕, 小川 徹, 小山 重人, 佐々木 啓一

    顎顔面補綴 44 (2) 83-83 2021/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  21. A Case Report of Restoring Oral Functions after Segmental Mandibulectomy with Surgical Reconstruction by Prosthodontic Rehabilitaion Peer-reviewed

    Naru Shiraishi

    44 (2) 64-70 2021/12

  22. Relationships Between Survival and Oral Status, Swallowing Function, and Oral Intake Level in Older Patients with Aspiration Pneumonia. International-journal

    Taku Suzuki, Takanori Tsujimura, Jin Magara, Naohito Hao, Naru Shiraishi, Kazuya Maekawa, Kazuo Matsushima, Makoto Inoue

    Dysphagia 37 (3) 558-566 2021/04/30

    DOI: 10.1007/s00455-021-10306-3  

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    The factors affecting the survival of patients with aspiration pneumonia (AP) remain unclear. This study aimed to determine whether factors, including oral status, swallowing function, and oral intake level, were related to survival outcomes in older patients hospitalized for AP. The study enrolled patients with AP who were admitted to our hospital between February 2017 and November 2019. Patients were divided into two groups based on the 90-day mortality after the first swallowing function evaluation: survivors and deceased. The data were compared between the two groups. A total of 29 patients were diagnosed with AP. Of these patients, 13 died within 90 days. The numbers of patients who could not use removable dentures and required sputum suctioning and had cough reflex at rest were significantly higher in the deceased than in the survivors. The salivary pooling and pharyngeal clearance scores evaluated by videoendoscopy, International Dysphagia Diet Standardisation Initiative Functional Diet Scale score determined after swallowing function evaluation, and consciousness level were significantly worse in the deceased than in the survivors. There were significant differences in patients' oral status, swallowing function, oral intake level, and consciousness level between the survivors and deceased.

  23. Sustained laryngeal transient receptor potential vanilloid 1 activation inhibits mechanically-induced swallowing in anesthetized rats. International-journal Peer-reviewed

    Midori Yoshihara, Takanori Tsujimura, Taku Suzuki, Kouta Nagoya, Naru Shiraishi, Jin Magara, Miho Terunuma, Makoto Inoue

    American journal of physiology. Gastrointestinal and liver physiology 319 (3) G412-G419 2020/08/05

    DOI: 10.1152/ajpgi.00082.2020  

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    A major component of gastric acid is hydrochloric acid (HCl), which can activate transient receptor potential vanilloid 1 (TRPV1). In the present study, we investigated how sustained laryngeal TRPV1 activation affects the frequency of the swallowing reflex. Experiments were carried out on 85 male Sprague-Dawley rats. The effects of short and sustained application of chemicals (3 µl of 0.1 N HCl or capsaicin) on the frequency of swallowing and of time-dependent changes in the occurrence of swallowing evoked by supralaryngeal nerve stimulation were determined. To evaluate vascular permeability of the larynx, Evans blue dye was intravenously injected after 5 or 60 min of sustained TRPV1 activation. SB366791 (a TRPV1 inhibitor) and Cap/QX-314 (a TRPV1-expressed neuronal inhibitor) significantly inhibited HCl/capsaicin-induced swallowing, but air flow-induced swallowing was not affected. Although the number of air flow-induced swallows induced by capsaicin stimulation was not affected within 5 min, but significantly reduced by 60-min capsaicin or HCl application. The swallowing threshold associated with supralaryngeal nerve stimulation did not significantly change throughout the recording period. Evans blue dye concentrations in the larynx were significantly higher at 60 min in the 10-5 M capsaicin group than in the other groups. Our results suggest that sustained TPRV1 activation not only desensitizes TRPV1, but also inactivates mechanoreceptors, which may be attributed to increases in vascular permeability and edema, as part of an inflammatory process.

  24. Design and Progress of Oral Health Examinations in the Tohoku Medical Megabank Project

    Akito Tsuboi, Hiroyuki Matsui, Naru Shiraishi, Takahisa Murakami, Akihito Otsuki, Junko Kawashima, Tomomi Kiyama, Toru Tamahara, Maki Goto, Shihoko Koyama, Junichi Sugawara, Eiichi N. Kodama, Hirohito Metoki, Atsushi Hozawa, Shinichi Kuriyama, Hiroaki Tomita, Masahiro Kikuya, Naoko Minegishi, Kichiya Suzuki, Seizo Koshiba, Gen Tamiya, Nobuo Fuse, Yuichi Aoki, Takako Takai-Igarashi, Soichi Ogishima, Tomohiro Nakamura, Mika Sakurai-Yageta, Fuji Nagami, Kengo Kinoshita, Shigeo Kure, Ritsuko Shimizu, Keiichi Sasaki, Masayuki Yamamoto

    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE 251 (2) 97-115 2020/06

    DOI: 10.1620/tjem.251.97  

    ISSN: 0040-8727

    eISSN: 1349-3329

  25. Effect of surface modification of Ti-6Al-4V alloy by electron cyclotron resonance plasma oxidation Peer-reviewed

    Mayumi OIKAWA, Hiroshi MASUMOTO, Naru SHIRAISHI, Yusuke ORII, Takahisa ANADA, Osamu SUZUKI, Keiichi SASAKI

    Dent Mater J 2020

    DOI: 10.4012/dmj.2020-051  

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    Ti-6Al-4V alloy is used as biomaterials for dental and orthopedic implants because of their excellent biocompatibilities and mechanical properties. However, it is unclear that electron cyclotron resonance (ECR) plasma oxidation can create the oxide films on Ti-6Al-4V alloy surface, and this technique improves the ability of its osseointegration. The purpose of this study was to investigate the characteristics and calcification ability of the oxide films. X-ray diffraction (XRD) peaks of rutile phase were intensified with increasing the temperature. Scanning electron microscopy (SEM) images showed a crater-like structure, and bonding strengths between the substrate and oxide film reached a maximum at 400°C. Calcium phosphate (CaP) compounds after calcification process were identified as octacalcium phosphate (OCP) and precipitation amount was maximized at 400°C. The results suggested that the altered surface of Ti-6Al-4V alloy by ECR plasma oxidation might have the potential of accelerating the ability of its osseointegration through enhancement of OCP.

  26. Oral health examinations in two large-scale genome cohort studies conducted by the Tohoku Medical Megabank Organization Peer-reviewed

    Akito Tsuboi, Hiroyuki Matsui, Naru Shiraishi, Takahisa Murakami, Akihito Otsuki, Junko Kawashima, Tomomi Kiyama, Toru Tamahara, Maki Goto, Shihoko Koyama, Junichi Sugawara, Eiichi N Kodama, Hirohito Metoki, Atsushi Hozawa, Shinichi Kuriyama, Hiroaki Tomita, Masahiro Kikuya, Naoko Minegishi, Kichiya Suzuki, Seizo Koshiba, Ritsuko Shimizu, Gen Tamiya, Nobuo Fuse, Yuichi Aoki, Takako Takai-Igarashi, Soichi Ogishima, Tomohiro Nakamura, Mika Sakurai, Fuji Nagami, Kengo Kinoshita, Shigeo Kure, Keiichi Sasaki, Masayuki Yamamoto

    Tohoku J Exp Med 2020

  27. Histomorphometric assessments of peri-implant bone around Ti-Nb-Sn alloy implants with low Young’s modulus Peer-reviewed

    Shiraishi N, Masumoto H, Takahashi K, Tenkumo T, Anada T, Suzuki O, Ogawa T, Sasaki K

    Dental Materials Journal 39 (1) 148-153 2020/01

    DOI: 10.4012/dmj.2018-376  

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    Many β-Ti alloys have been developed for, and used in, medical devices because of the corrosion resistance, biocompatibility, and exceptionally low Young's modulus. The aim of the present study was to investigate the histomorphometric aspects of peri-implant bone around Ti-Nb-Sn alloy implants and compare them with those in the case of commercially pure Ti (Ti). Fluorescent morphological observations of ST-2 cells on the substrate were performed and bone morphogenesis around implants in rat femur was evaluated. There was no difference between the cell morphology on Ti and those on the Ti-Nb-Sn alloy during observation for 24 h. A comparison of the Ti-Nb-Sn alloy implant and the Ti implant showed no significant differences between the bone-to-implant contact ratios or the bone fractions. These results suggest that the biological adaptations with Ti-Nb-Sn implants during a healing period are similar to those with Ti. Ti-Nb-Sn is therefore suitable for use in dental implants.

  28. 摂食嚥下リハビリテーションを実施したクロウ・深瀬(POEMS)症候群の1例

    羽尾 直仁, 辻村 恭憲, 白石 成, 井上 誠

    新潟歯学会雑誌 49 (1) 19-24 2019/06

    Publisher: 新潟歯学会

    ISSN: 0385-0153

  29. Involvement of the epithelial sodium channel in initiation of mechanically evoked swallows in anaesthetized rats Peer-reviewed

    Takanori Tsujimura, Rumi Ueha, Midori Yoshihara, Eri Takei, Kouta Nagoya, Naru Shiraishi, Jin Magara, Makoto Inoue

    Journal of Physiology 597 (11) 2949-2963 2019/06/01

    DOI: 10.1113/JP277895  

    ISSN: 0022-3751

    eISSN: 1469-7793

  30. Effect of Functionally-Graded Calcium Titanate Film, Prepared by Metal-Organic Chemical Vapor Deposition, on Titanium Implant Peer-reviewed

    Naru Shiraishi, Risa Ishiko-Uzuka, Kenta Takahashi, Toru Ogawa, Takahisa Anada, Osamu Suzuki, Takashi Goto, Keiichi Sasaki

    Applied Sciences 9 (1) 172-182 2019/01

    DOI: 10.3390/app9010172  

    eISSN: 2076-3417

  31. 舌癌術後の摂食嚥下障害に対し間接訓練ならびに直接訓練を実施した1症例

    小貫 和佳奈, 笹 杏奈, 辻 光順, 渡邊 賢礼, 白石 成, 伊藤 加代子, 真柄 仁, 辻村 恭憲, 井上 誠

    新潟歯学会雑誌 48 (1) 43-48 2018/06

    Publisher: 新潟歯学会

    ISSN: 0385-0153

  32. Involvement of hypoglossal and recurrent laryngeal nerves on swallowing pressure Peer-reviewed

    Takanori Tsujimura, Taku Suzuki, Midori Yoshihara, Shogo Sakai, Naomi Koshi, Hirokazu Ashiga, Naru Shiraishi, Kojun Tsuji, Jin Magara, Makoto Inoue

    Journal of Applied Physiology 124 (5) 1148-1154 2018/05/01

    Publisher: American Physiological Society

    DOI: 10.1152/japplphysiol.00944.2017  

    ISSN: 8750-7587 1522-1601

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    <jats:p> Swallowing pressure generation is important to ensure safe transport of an ingested bolus without aspiration or leaving residue in the pharynx. To clarify the mechanism, we measured swallowing pressure at the oropharynx (OP), upper esophageal sphincter (UES), and cervical esophagus (CE) using a specially designed manometric catheter in anesthetized rats. A swallow, evoked by punctate mechanical stimulation to the larynx, was identified by recording activation of the suprahyoid and thyrohyoid muscles using electromyography (EMG). Areas under the curve of the swallowing pressure at the OP, UES, and CE from two trials indicated high intrasubject reproducibility. Effects of transecting the hypoglossal nerve (12N) and recurrent laryngeal nerve (RLN) on swallowing were investigated. Following bilateral hypoglossal nerve transection (Bi-12Nx), OP pressure was significantly decreased, and time intervals between peaks of thyrohyoid EMG bursts and OP pressure were significantly shorter. Decreased OP pressure and shortened times between peaks of thyrohyoid EMG bursts and OP pressure following Bi-12Nx were significantly increased and longer, respectively, after covering the hard and soft palates with acrylic material. UES pressure was significantly decreased after bilateral RLN transection compared with that before transection. These results suggest that the 12N and RLN play crucial roles in OP and UES pressure during swallowing, respectively. We speculate that covering the palates with a palatal augmentation prosthesis may reverse the reduced swallowing pressure in patients with 12N or tongue damage by the changes of the sensory information and of the contact between the tongue and a palates. </jats:p><jats:p> NEW &amp; NOTEWORTHY Hypoglossal nerve transection reduced swallowing pressure at the oropharynx. Covering the hard and soft palates with acrylic material may reverse the reduced swallowing function caused by hypoglossal nerve damage. Recurrent laryngeal nerve transection reduced upper esophageal sphincter negative pressure during swallowing. </jats:p>

  33. Introduction of Integrated Dental Training Jaw Models and Rubric Criteria Peer-reviewed

    Taichi Tenkumo, Takeshi Fuji, Motohide Ikawa, Shigeru Shoji, Hiromi Sasazaki, Yoko Iwamatsu-Kobayashi, Yayoi Okuyama, Hiroyuki Matsui, Naru Shiraishi, Toshi Furuuchi, Keisuke Higuchi, Wataru Hashimoto, Yasuhisa Takeuchi, Hidetoshi Simauchi, Keiichi Sasaki

    European Journal of Dental Education 2018

  34. Development of semi-automatic procedure for detection and tracking of fiducial markers for orofacial kinematics during natural feeding

    Filiz Bunyak, Naru Shiraishi, Kannappan Palaniappan, Teresa E. Lever, Limor Avivi-Arber, Kazutaka Takahashi

    2017/07

    Publisher: 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

    DOI: 10.1109/embc.2017.8036891  

  35. Case report of dysphagia following hypoxic ischemic encephalopathy Peer-reviewed

    Midori Yoshihara, Yukiko Uemura, Mayumi Ohkuchi, Yukako Sunada, Chikako Takeuchi, Naru Shiraishi, Takanori Tsujimura, Makoto Inoue

    47 (1) 33-37 2017

  36. 東北大学病院における頭頸部腫瘍リハビリテーション期患者への歯科衛生士による専門的口腔ケアの実態調査

    宍戸 敦子, 佐藤 奈央子, 小山 重人, 白石 成, 塙 総司, 佐々木 啓一

    顎顔面補綴 38 (2) 43-46 2015/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

  37. Biomechanical Evaluation of Ti-Nb-Sn Alloy Implants with a Low Young's Modulus Peer-reviewed

    Kenta Takahashi, Naru Shiraishi, Risa Ishiko-Uzuka, Takahisa Anada, Osamu Suzuki, Hiroshi Masumoto, Keiichi Sasaki

    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 16 (3) 5779-5788 2015/03

    DOI: 10.3390/ijms16035779  

    ISSN: 1422-0067

  38. 東北大学病院顎口腔再建治療部で対応した頭頚部領域腫瘍、先天性疾患、ならびに外傷を有する患者の実態調査 Peer-reviewed

    佐藤奈央子, 白石成, 小山重人, 石河理紗, 神藤佑亮, 竹内裕尚, 冨士岳士, 塙総司, 佐々木啓一

    顎顔面補綴 37 (2) 60-63 2014

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  39. 宮城県立精神医療センター入院患者における歯科保健指導方法の確立に向けた基礎調査 Peer-reviewed

    小山重人, 白石 成, 塙 総司, 細川亮一, 小関健由, 伊藤恵美, 石河理紗, 松井裕之, 水戸武彦, 貴田岡亜希, 佐々木啓一, 相田 潤, 小坂 健, 及川祐司, 小髙 晃

    みちのく歯学会雑誌 45 (1-2) 53-55 2014

    Publisher: 東北地区歯科医学会

    ISSN: 0385-0099

  40. Biomechanical Evaluation of Amorphous Calcium Phosphate Coated TNTZ Implants Prepared Using a Radiofrequency Magnetron Sputtering System Peer-reviewed

    Naru Shiraishi, Rong Tu, Risa Uzuka, Takahisa Anada, Takayuki Narushima, Takashi Goto, Mitsuo Niinomi, Keiichi Sasaki, Osamu Suzuki

    MATERIALS TRANSACTIONS 53 (7) 1343-1348 2012/07

    DOI: 10.2320/matertrans.M2012078  

    ISSN: 1345-9678

    eISSN: 1347-5320

  41. Calcium phosphate-coated titanium alloy implants prepared by radiofrequency magnetron sputtering: A review Peer-reviewed

    Naru Shiraishi, Yuko Suzuki, Naoko Sato, Takahisa Anada, Takashi Goto, Rong Tu, Mitsuo Niinomi, Takayuki Narushima, Kyosuke Ueda, Risa Uzuka, Osamu Suzuki, Keiichi Sasaki

    Interface Oral Health Science 2011 352-354 2012/01/01

    Publisher: Springer Japan

    DOI: 10.1007/978-4-431-54070-0_102  

  42. Proteome analysis of rat serum proteins adsorbed onto synthetic octacalcium phosphate crystals

    Hirofumi Kaneko, Junichi Kamiie, Hirotaka Kawakami, Takahisa Anada, Yoshitomo Honda, Naru Shiraishi, Shinji Kamakura, Tetsuya Terasaki, Hidetoshi Shimauchi, Osamu Suzuki

    ANALYTICAL BIOCHEMISTRY 418 (2) 276-285 2011/11

    DOI: 10.1016/j.ab.2011.07.022  

    ISSN: 0003-2697

    eISSN: 1096-0309

  43. 可撤性部分床義歯装着患者の残存歯歯周組織状態に対するメインテナンスケアの効果

    冨士 岳志, 花渕 静, 小山 重人, 依田 信裕, 佐々木 具文, 横山 政宣, 小川 徹, 塙 総司, 佐藤 奈央子, 重光 竜二, 末永 華子, 折居 雄介, 赤塚 亮, 白石 成, 竹内 裕尚, 佐々木 啓一

    日本補綴歯科学会誌 3 (特別号) 207-207 2011/05

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  44. 可撤性部分床義歯症例の長期経過に関する後ろ向きコホート研究

    冨士 岳志, 小山 重人, 依田 信裕, 伊奈 慶典, 佐々木 具文, 羽鳥 弘毅, 横山 政宣, 塙 総司, 佐藤 奈央子, 重光 竜二, 末永 華子, 折居 雄介, 赤塚 亮, 白石 成, 竹内 裕尚, 佐々木 啓一

    日本補綴歯科学会誌 3 (1) E29-E29 2011/01

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  45. Preparation and characterization of porous alginate scaffolds containing various amounts of octacalcium phosphate (OCP) crystals Peer-reviewed

    Naru Shiraishi, Takahisa Anada, Yoshitomo Honda, Taisuke Masuda, Keiichi Sasaki, Osamu Suzuki

    JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 21 (3) 907-914 2010/03

    DOI: 10.1007/s10856-009-3911-1  

    ISSN: 0957-4530

  46. 超音波顕微鏡を利用したラット下顎頭軟骨弾性の経時的変化

    羽鳥 弘毅, 萩原 嘉廣, 西條 芳文, 安藤 晃, 伊奈 慶典, 安藤 浩二, 白石 成, 佐藤 奨, 佐々木 啓一

    日本補綴歯科学会誌 2 (1) E19-E19 2010/01

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  47. 超音波顕微鏡を利用したラット臼歯歯根膜弾性の経時的変化

    佐藤 奨, 萩原 嘉廣, 西條 芳文, 安藤 晃, 伊奈 慶典, 安藤 浩二, 白石 成, 羽鳥 弘毅, 佐々木 啓一

    日本補綴歯科学会誌 1 (1) E41-E41 2009/01

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

Show all ︎Show first 5

Misc. 28

  1. Functional training methods that activates oral and cognitive functions: Effect verification through double-blind RCT

    阿部真澄, 野内類, 小川徹, 白石成, 日原大貴, 豊岡継泰, 土井千章, 檜山聡, 佐々木啓一, 江草宏, 依田信裕

    日本補綴歯科学会誌(Web) 16 2024

    ISSN: 1883-6860

  2. 下顎骨エナメル上皮腫に対する反復処置法に顎補綴で対応した1症例

    畠山 高徳, 佐藤 奈央子, 互野 亮, 泉田 一賢, 小坂 萌, 白石 成, 山内 健介, 小山 重人

    顎顔面補綴 46 (2) 53-53 2023/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  3. 東北大学病院嚥下治療センター・歯科における筋萎縮性側索硬化症(ALS)患者に対する介入の実態 ALSの重症度と口腔機能の関連

    互野 亮, 白石 成, 千葉 智弘, 砂田 慶一, 小川 徹, 小山 重人

    顎顔面補綴 46 (2) 59-59 2023/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  4. 下顎歯肉癌の口腔顎顔面再建に顎補綴で対応した1症例

    佐藤 奈央子, 互野 亮, 森島 浩允, 畠山 高徳, 小坂 萌, 白石 成, 泉田 一賢, 山内 健介, 小山 重人

    顎顔面補綴 46 (2) 61-61 2023/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  5. 多職種・多部門が連携した誤嚥・窒息事故防止のための取り組み

    田畑 雅央, 平野 愛, 太田 淳, 白石 成, 土肥 千秋, 香取 幸夫

    医療の質・安全学会誌 18 (Suppl.) 364-364 2023/11

    Publisher: (一社)医療の質・安全学会

    ISSN: 1881-3658

    eISSN: 1882-3254

  6. Verification of brain activity during cognitive and oral functional training in young adults

    阿部真澄, 野内類, 依田信裕, 小川徹, 白石成, 日原大貴, 佐々木啓一, 江草宏

    日本補綴歯科学会誌(Web) 15 2023

    ISSN: 1883-6860

  7. Medical-Dental collaboration: Exploratory research project on the Correlation between Cognitive and Oral function (ECCO): background and research activity Invited

    Ann Jpn Prosthodont Soc 1 (15) 72-78 2023/01

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  8. 口腔内スキャナを用いた下顎区域切除後の下顎偏位評価と影響因子の検討

    互野 亮, 佐藤 奈央子, 泉田 一賢, 畠山 高徳, 白石 成, 依田 信裕, 小川 徹, 小山 重人, 佐々木 啓一

    顎顔面補綴 45 (2) 62-63 2022/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  9. 【窒息ゼロを目指す】実践報告 東北大学病院(宮城県仙台市青葉区)誤嚥・窒息予防のための多職種・多部門の連携

    田畑 雅央, 平野 愛, 太田 淳, 白石 成, 土肥 千秋, 香取 幸夫

    患者安全推進ジャーナル (70) 18-23 2022/12

    Publisher: (公財)日本医療機能評価機構

  10. 認知症および軽度認知障害患者に関する医科歯科連携の意識調査 ECCOプロジェクト

    釘宮 嘉浩, 眞鍋 雄太, 笛木 賢治, 上田 貴之, 橋本 衛, 白石 成, 石川 智久, 内海 久美子, 稲用 友佳, 安部 友佳, 長島 信太朗, 井上 允, 窪木 拓男, 木本 克彦, 佐々木 啓一, 池田 学, 馬場 一美

    日本補綴歯科学会誌 14 (特別号) 347-347 2022/07

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  11. 認知機能と口腔機能の相関に関する医師・歯科医師アンケート ECCOプロジェクト

    笛木 賢治, 眞鍋 雄太, 上田 貴之, 橋本 衛, 釘宮 嘉浩, 白石 成, 石川 智久, 内海 久美子, 稲用 友佳, 安部 友佳, 長島 信太朗, 井上 允, 窪木 拓男, 木本 克彦, 佐々木 啓一, 池田 学, 馬場 一美

    日本補綴歯科学会誌 14 (特別号) 348-348 2022/07

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  12. 認知症および軽度認知障害患者に関する医科歯科連携の意識調査 ECCOプロジェクト

    釘宮 嘉浩, 眞鍋 雄太, 笛木 賢治, 上田 貴之, 橋本 衛, 白石 成, 石川 智久, 内海 久美子, 稲用 友佳, 安部 友佳, 長島 信太朗, 井上 允, 窪木 拓男, 木本 克彦, 佐々木 啓一, 池田 学, 馬場 一美

    日本補綴歯科学会誌 14 (特別号) 347-347 2022/07

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  13. 認知機能と口腔機能の相関に関する医師・歯科医師アンケート ECCOプロジェクト

    笛木 賢治, 眞鍋 雄太, 上田 貴之, 橋本 衛, 釘宮 嘉浩, 白石 成, 石川 智久, 内海 久美子, 稲用 友佳, 安部 友佳, 長島 信太朗, 井上 允, 窪木 拓男, 木本 克彦, 佐々木 啓一, 池田 学, 馬場 一美

    日本補綴歯科学会誌 14 (特別号) 348-348 2022/07

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  14. 舌がん患者の外科的治療術前・後における舌圧と口腔機能との関連

    互野 亮, 小山 重人, 白石 成, 泉田 一賢, 小宮山 貴将, 佐藤 奈央子, 小川 徹, 佐々木 啓一

    日本補綴歯科学会誌 14 (特別号) 284-284 2022/07

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  15. オクルーザルスプリントの使用により下顎偏位の改善を見た下顎骨片側離断後の再建症例

    互野 亮, 佐藤 奈央子, 泉田 一賢, 畠山 高徳, 白石 成, 小坂 萌, 依田 信裕, 小川 徹, 小山 重人, 佐々木 啓一

    顎顔面補綴 44 (2) 83-83 2021/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  16. デジタル時代に学ぶ咬合学NEO 顎口腔機能と補綴装置(第6回) 嚥下と補綴治療・装置(後)

    白石 成, 互野 亮, 佐々木 啓一

    歯科技工 49 (6) 596-607 2021/06

    Publisher: 医歯薬出版(株)

    ISSN: 0389-1895

  17. デジタル時代に学ぶ 咬合学NEO 顎口腔機能と補綴装置(第5回) 嚥下と補綴治療・装置(前)

    白石 成, 互野 亮, 佐々木 啓一

    歯科技工 49 (5) 515-525 2021/05

    Publisher: 医歯薬出版(株)

    ISSN: 0389-1895

  18. 摂食嚥下リハビリテーションを実施したクロウ・深瀬(POEMS)症候群の1例 Peer-reviewed

    羽尾 直仁, 辻村 恭憲, 白石 成, 井上 誠

    新潟歯学会雑誌 49 (1) 19-24 2019/06

    Publisher: 新潟歯学会

    ISSN: 0385-0153

  19. 頚静脈孔神経鞘腫術後に嚥下障害を認めてバルーン訓練が奏功した一例

    日野遥香, 那小屋公太, 白石成, 鈴見梨紗, 上村由紀子, 高波里帆, KULVANICH Sirima, 井上誠

    日本摂食嚥下リハビリテーション学会学術大会抄録集(Web) 25th 2019

  20. 神経筋変性疾患患者における舌圧と嚥下機能の評価

    真柄 仁, 白石 成, 井上 誠

    日本補綴歯科学会誌 10 (特別号) 258-258 2018/06

    Publisher: (公社)日本補綴歯科学会

    ISSN: 1883-4426

    eISSN: 1883-6860

  21. 舌癌術後の摂食嚥下障害に対し間接訓練ならびに直接訓練を実施した1症例 Peer-reviewed

    小貫 和佳奈, 笹 杏奈, 辻 光順, 渡邊 賢礼, 白石 成, 伊藤 加代子, 真柄 仁, 辻村 恭憲, 井上 誠

    新潟歯学会雑誌 48 (1) 43-48 2018/06

    Publisher: 新潟歯学会

    ISSN: 0385-0153

  22. 頭頸部腫瘍患者における切除術前・術後・補綴後のQOL調査

    石河 理紗, 佐藤 奈央子, 白石 成, 神藤 佑亮, 小山 重人, 佐々木 啓一

    顎顔面補綴 38 (2) 86-86 2015/12

    Publisher: (一社)日本顎顔面補綴学会

    ISSN: 0389-4045

    eISSN: 2435-0389

  23. P-72 The mechanobiological availability of Ti-Nb-Sn with low young's modulus and high-strength

    Takahashi K, Shiraishi N, Ishiko-Uzuka R, Anada T, Suzuki O, Masumoto H, Sasaki K

    The journal of the Japanese Society for Dental Materials and Devices 33 (5) 477-477 2014/09/20

    Publisher: The Japanese Society for Dental Materials and Devices (JSDMD)

    ISSN: 1884-4421

    More details Close

    It is reported that Ti-Nb-Sn has low Young's modulus possessing around 40 GPa close to human cortical bone (30 GPa) and low cytotoxicity as well as commercially pure Ti (cpTi). However, the availability for dental implant is unknown. The purpose of this study was to investigate the biomechanical behavior, biocompatibility and bioactivity of Ti-Nb-Sn. As a result, Ti-Nb-Sn is considered to have sufficient biological potential and capacity for osseointegration.

  24. The effect of amorphous calcium phosphate films by radiofrequency magnetron sputtering on TNTZ implants on integration with bone

    SHIRAISHI N, NARUSHIMA T, GOTO T, NIINOMI M, SUZUKI O, SASAKI K

    The journal of the Japanese Society for Dental Materials and Devices 31 (5) 385-385 2012/09/25

    Publisher: The Japanese Society for Dental Materials and Devices (JSDMD)

    ISSN: 1884-4421

    More details Close

    Ti-29Nb-13Ta-4.6Zr alloy (TNTZ) has excellent advantages as a biomaterial, such as low Young's modulus, low cytotoxicity, and the absence of allergens. However, it is unclear whether TNTZ can achieve sufficient osseointegration as a dental implant. The effectiveness of surface modification of TNTZ implants with amorphous calcium phosphate (ACP) by radiofrequency (RF) magnetron sputtering is also unclear. We investigated the biomechanical behaviors of TNTZ implants in vivo. The results suggest that TNTZ implants can achieve osseointegration similar to that of pure Ti, and that surface modification with ACP by RF magnetron sputtering improves osseointegration.

  25. Proteome analysis of rat serum proteins adsorbed onto synthetic octacalcium phosphate crystals (vol 418, pg 276, 2011)

    Hirofumi Kaneko, Junichi Kamiie, Hirotaka Kawakami, Takahisa Anada, Yoshitomo Honda, Naru Shiraishi, Shinji Kamakura, Tetsuya Terasaki, Hidetoshi Shimauchi, Osamu Suzuki

    ANALYTICAL BIOCHEMISTRY 420 (2) 198-198 2012/01

    DOI: 10.1016/j.ab.2011.09.023  

    ISSN: 0003-2697

  26. 後向きコホート調査による可撤性部分床義歯症例の長期経過 (みちのく歯学会雑誌) Peer-reviewed

    冨士岳志, 小山重人, 依田信裕, 伊奈慶典, 佐々木具文, 羽鳥弘毅, 横山政宣, 小川徹, 塙総司, 佐藤奈央子, 重光竜二, 末永華子, 折居雄介, 赤塚亮, 白石成, 竹内裕尚, 佐々木啓一

    みちのく歯学会雑誌 41 (1-2) 73-74 2010/12

    Publisher: 東北地区歯科医学会

    ISSN: 0385-0099

  27. New Inorganic-organic hybrid scaffolds for bone regeneration

    SHIRAISHI N, ANADA T, HONDA Y, SASAKI K, SUZUKI O

    The journal of the Japanese Society for Dental Materials and Devices 29 (5) 458-458 2010/09/20

    Publisher: The Japanese Society for Dental Materials and Devices (JSDMD)

    ISSN: 1884-4421

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    The aim of this study is to fabricate the new inorganic-organic hybrid scaffolds for bone regeneration. The conditions required are osteoconductivity for inorganic material and biocompatibility, biodegradability, low immunogenicity, optimum mechanical strength and pore formation for organic material. For this purposes, we selected the β-TCP and gluten. The complex was mixed with water and then burned to prepare 6 types of Gluten/β-TCP scaffolds. The property of the scaffold, including the pore size and the mechanical strength was investigated.

  28. Preparation and characterization of porous alginate/octacalcium phosphate scaffolas

    SHIRAISHI N, ANADA T, HONDA Y, MASUDA T, SASAKI K, SUZUKI O

    Journal of the Japanese Society for Dental Materials and Devices 28 (5) 271-271 2009/09/10

    Publisher: The Japanese Society for Dental Materials and Devices (JSDMD)

    ISSN: 0286-5858

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    We previously fabricated alginate(Alg) / octacalcium phosphate(OCP) scaffolds by co-precipitation method (OCP-precipitated Alg), and demonstrated that increasing pore size improved cell attachment in vitro and bone regeneration in vivo. The present study was designed to investigate whether the amount of OCP affects the material characteristics, such as the pore size, when the granules of OCP are mixed in Alg. The results showed that immersion of Alg/OCP in SBF promoted OCP conversion and apatite deposition, suggesting that the Alg/OCP may have osteoconductive nature. The pore size of the composites was dependent on the amount of OCP.

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Books and Other Publications 2

  1. 歯科医療から認知症にどう取り組むべきか? 4 ここまではわかっている! 口腔機能と認知症の関係(1)―基礎研究からのアプローチ

    小林琢也, 白石 成, 木本克彦, 佐々木啓一

    歯界展望 医歯薬出版 2023/10

  2. 歯科医療から認知症にどう取り組むべきか? 連載緒言

    佐々木啓一, 白石成

    歯界展望 医歯薬出版 2023/07

Research Projects 10

  1. Development of a new swallowing assessment based on musculoskeletal simulation

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2023/04/01 - 2026/03/31

  2. Neurophysiological analysis of oral function improvement using diffusion tensor imaging

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2023/04/01 - 2026/03/31

  3. Effect of prosthodontic treatment on conscious swallowing function

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2022/04/01 - 2025/03/31

  4. Research of a novel treatment for dysphagia focusing on cell protection and anti-inflammatory effects of transcription factor Nrf2

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (B)

    Institution: Tohoku University

    2022/04/01 - 2025/03/31

  5. Researching for a dysphagia using pathological animal model

    Shiraishi Naru

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2019/04/01 - 2022/03/31

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    We succeeded in recording the muscle activities involved in mastication and swallowing from an unrestrained rat. It was possible to identify the timing of swallowing from the muscle activity record and its sound. Analysis was performed using the created model, and although there were no individual differences in the parameter for mastication, it was suggested that there was a difference in the swallowing parameters (ex thyrohyoid muscle activity). The effect of ligation of the external carotid artery, which is the feeding artery in the maxillofacial region, was not observed electromyographically in a short period after ligation.

  6. Electromyographic evaluation of the swallowing training by magnetic stimulation.

    Hanawa Soshi

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2018/04/01 - 2021/03/31

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    This study focused on the fact that the newly developed magnetic stimulator can cause muscle contraction with less painful stimuli than electrical stimulation; thus, we applied muscle contraction to the suprahyoid muscles. We aim to strengthen the anterior-upper elevation of the hyoid bone, which is a necessary movement for swallowing and effective swallowing training. During this research period, the conditions for magnetic stimulation were established, and clinical research was started with the approval of the Hospital Ethics Review Committee. It is expected that the results of this study will enable more patients to receive less painful and practical training for patients with swallowing disorders.

  7. マルチチャンネルレコーディングシステムを利用した摂食嚥下機能時の大脳皮質活動記録 Competitive

    白石成

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 基盤研究(C)

    2016/04 - 2019/03

  8. 応力自律的制御を有する低弾性チタン製インプラントの周囲骨動態の生体力学的検証

    白石 成

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 基盤研究(C)

    Institution: 東北大学

    2015/04/01 - 2018/03/31

  9. 生体アパタイトの配向性をパラメータとしたインプラント周囲骨の新規評価方法の提案 Competitive

    白石成

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究(B)

    2013/04 - 2015/03

  10. 低弾性インプラントのメカノバイオロジーとストレスシールディング効果 Competitive

    白石成

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究(B)

    2011/04 - 2013/03

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