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博士(理学) (The University of Tokyo)
Details of the Researcher
Research History 3
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2001/02 - 2005/01Division of Biology, California Institute of Technology Postdoctoral Scholar in Biology
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2000/05 - 2001/02Graduate School of Frontier Sciences, the University of Tokyo Visiting Research Associate
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1997/10 - 2000/04Department of Life Science, Tokyo Institute of Technology Research Associate
Education 2
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The University of Tokyo Graduate School, Division of Science 生物科学専攻
- 1997/09
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Hirosaki University Faculty of Science 生物学科
- 1992/03
Committee Memberships 2
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日本動物学会 男女共同参画委員会 委員
2016/10 - 2019/09
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日本動物学会 キャリアパス小委員会 委員
2016/10 - 2019/09
Professional Memberships 1
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The Zoological Society of Japan
Research Interests 2
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進化
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個体発生
Research Areas 2
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Life sciences / Evolutionary biology /
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Life sciences / Developmental biology /
Awards 1
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生命科学研究科研究奨励賞
2005/11/08 東北大学大学院生命科学研究科 「形態と生活史の多様性を生み出す個体発生機構の進化に関する研究」
Papers 39
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Records of the galeommatoid bivalve Nipponomysella subtruncata (Yokoyama, 1927), a commensal with the sipunculan Siphonosoma cumanense (Keferstein, 1867) from Miyagi and Aomori Prefectures, Japan
(34) 109-114 2023/03
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An easy and rapid staining method for confocal microscopic observation and reconstruction of three‐dimensional images of echinoderm larvae and juveniles Peer-reviewed
Kohei Tokanai, Yasuhiro Kamei, Takuya Minokawa
Development, Growth & Differentiation 63 (9) 478-487 2021/12
Publisher: WileyDOI: 10.1111/dgd.12758
ISSN: 0012-1592
eISSN: 1440-169X
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Meiobenthic Polychaete Dinophilus sp. cf. gyrociliatus (Annelida: Dinophilidae) from Japan with SEM Observation and DNA Barcodes Peer-reviewed
Naoto Jimi, Takuya Minokawa, Toru Miura, Hiroshi Kajihara
Species Diversity 25 (2) 213-218 2020/09/18
Publisher: Japanese Society of Systematic ZoologyISSN: 1342-1670
eISSN: 2189-7301
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Pmar1/phb homeobox genes and the evolution of the double-negative gate for endomesoderm specification in echinoderms. International-journal Peer-reviewed
Atsuko Yamazaki, Yoshiaki Morino, Makoto Urata, Masaaki Yamaguchi, Takuya Minokawa, Ryohei Furukawa, Mariko Kondo, Hiroshi Wada
Development (Cambridge, England) 2020/01/30
DOI: 10.1242/dev.182139
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Cidaroids, clypeasteroids, and spatangoids: Procurement, culture, and basic methods Invited Peer-reviewed
Hibino T, Minokawa T, Yamazaki A
Methods in Cell Biology 150 81-103 2019
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Development of the coelomic cavities in larvae of the living isocrinid sea lily Metacrinus rotundus Peer-reviewed
Amemiya S, Hibino T, Minokawa T, Naruse K, Kamei Y, Uemura I, Kiyomoto M, Hisanaga S, Kuraishi R
Acta Zool. 100 (E-Pub) 414-430 2018/09
Publisher: WileyDOI: 10.1111/azo.12274
ISSN: 0001-7272
eISSN: 1463-6395
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Anteroposterior molecular registries in ectoderm of the echinus rudiment Peer-reviewed
Adachi S, Niimi I, Sakai Y, Sato F, Minokawa T, Urata M, Sehara-Fujisawa A, Kobayashi I, Yamaguchi M
Developmental Dynamics 247 (12) 1297-1307 2018
Publisher: WileyDOI: 10.1002/dvdy.24686
ISSN: 1058-8388
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Comparative studies on the skeletogenic mesenchyme of echinoids Invited Peer-reviewed
Takuya Minokawa
DEVELOPMENTAL BIOLOGY 427 (2) 212-218 2017/07
DOI: 10.1016/j.ydbio.2016.11.011
ISSN: 0012-1606
eISSN: 1095-564X
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Characterization of paramyosin and thin filaments in the smooth muscle of acorn worm, a member of hemichordates Peer-reviewed
Hiroki Sonobe, Takashi Obinata, Takuya Minokawa, Tomohiro Haruta, Yuuki Kawamura, Shinryu Wakatsuki, Naruki Sato
JOURNAL OF BIOCHEMISTRY 160 (6) 369-379 2016/12
DOI: 10.1093/jb/mvw047
ISSN: 0021-924X
eISSN: 1756-2651
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Roles of hesC and gcm in echinoid larval mesenchyme cell development Peer-reviewed
Atsuko Yamazaki, Takuya Minokawa
DEVELOPMENT GROWTH & DIFFERENTIATION 58 (3) 315-326 2016/04
DOI: 10.1111/dgd.12277
ISSN: 0012-1592
eISSN: 1440-169X
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Early stalked stages in ontogeny of the living isocrinid sea lily Metacrinus rotundus Peer-reviewed
Shonan Amemiya, Akihito Omori, Toko Tsurugaya, Taku Hibino, Masaaki Yamaguchi, Ritsu Kuraishi, Masato Kiyomoto, Takuya Minokawa
ACTA ZOOLOGICA 97 (1) 102-116 2016/01
DOI: 10.1111/azo.12109
ISSN: 0001-7272
eISSN: 1463-6395
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Neurogenesis in directly and indirectly developing enteropneusts: of nets and cords Peer-reviewed
Sabrina Kaul-Strehlow, Makoto Urata, Takuya Minokawa, Thomas Stach, Andreas Wanninger
ORGANISMS DIVERSITY & EVOLUTION 15 (2) 405-422 2015/06
DOI: 10.1007/s13127-015-0201-2
ISSN: 1439-6092
eISSN: 1618-1077
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Expession patterns of mesenchyme specification genes in two distantly related echinoids, Glyptocidaris crenularis and Echinocardium cordatum Peer-reviewed
Atsuko Yamazaki, Takuya Minokawa
GENE EXPRESSION PATTERNS 17 (2) 87-97 2015/03
DOI: 10.1016/j.gep.2015.03.003
ISSN: 1567-133X
eISSN: 1872-7298
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Larval mesenchyme cell specification in the primitive echinoid occurs independently of the double-negative gate Peer-reviewed
Atsuko Yamazaki, Yumi Kidachi, Masaaki Yamaguchi, Takuya Minokawa
DEVELOPMENT 141 (13) 2669-2679 2014/07
DOI: 10.1242/dev.104331
ISSN: 0950-1991
eISSN: 1477-9129
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"Micromere" formation and expression of endomesoderm regulatory genes during embryogenesis of the primitive echinoid Prionocidaris baculosa Peer-reviewed
Atsuko Yamazaki, Yumi Kidachi, Takuya Minokawa
DEVELOPMENT GROWTH & DIFFERENTIATION 54 (5) 566-578 2012/06
DOI: 10.1111/j.1440-169X.2012.01360.x
ISSN: 0012-1592
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First record of Balanoglossus misakiensis Kuwano, 1902 (Phylum HEMICHORDATA) in Mutsu Bay, Aomori Prefecture
阿部広和, 鷲尾正彦, 山嵜敦子, 美濃川拓哉, 西川輝昭
青森自然誌研究 2012
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Role of the Nanos Homolog During Sea Urchin Development Peer-reviewed
Takayoshi Fujii, Naoaki Sakamoto, Hiroshi Ochiai, Kazumasa Fujita, Yuka Okamitsu, Noriko Sumiyoshi, Takuya Minokawa, Takashi Yamamoto
DEVELOPMENTAL DYNAMICS 238 (10) 2511-2521 2009/10
DOI: 10.1002/dvdy.22074
ISSN: 1058-8388
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Evolutionary modification of T-brain (tbr) expression patterns in sand dollar Peer-reviewed
Keiko Minemura, Masaaki Yamaguchi, Takuya Minokawa
GENE EXPRESSION PATTERNS 9 (7) 468-474 2009/10
DOI: 10.1016/j.gep.2009.07.008
ISSN: 1567-133X
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Evolutionary modification of specification for the endomesoderm in the direct developing echinoid Peronella japonica: loss of the endomesoderm-inducing signal originating from micromeres Peer-reviewed
Minoru Iijima, Yasuhiro Ishizuka, Yoko Nakajima, Shonan Amemiya, Takuya Minokawa
DEVELOPMENT GENES AND EVOLUTION 219 (5) 235-247 2009/05
DOI: 10.1007/s00427-009-0286-8
ISSN: 0949-944X
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Expression patterns of wnt8 orthologs in two sand dollar species with different developmental modes Peer-reviewed
Hidewo Nakata, Takuya Minokawa
GENE EXPRESSION PATTERNS 9 (3) 152-157 2009/03
DOI: 10.1016/j.gep.2008.11.004
ISSN: 1567-133X
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cis-regulatory inputs of the wnt8 gene in the sea urchin endomesoderm network Peer-reviewed
T Minokawa, AH Wikramanayake, EH Davidson
DEVELOPMENTAL BIOLOGY 288 (2) 545-558 2005/12
DOI: 10.1016/j.ydbio.2005.09.047
ISSN: 0012-1606
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Molecular heterotopy in the expression of Brachyury orthologs in order Clypeasteroida (irregular sea urchins) and order Echinoida (regular sea urchins) Peer-reviewed
T Hibino, Y Harada, T Minokawa, M Nonaka, S Amemiya
DEVELOPMENT GENES AND EVOLUTION 214 (11) 546-558 2004/11
DOI: 10.1007/s00427-004-0437-x
ISSN: 0949-944X
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R11: a cis-regulatory node of the sea urchin embryo gene network that controls early expression of SpDelta in micromeres Peer-reviewed
R Revilla-i-Domingo, T Minokawa, EH Davidson
DEVELOPMENTAL BIOLOGY 274 (2) 438-451 2004/10
DOI: 10.1016/j.ydbio.2004.07.008
ISSN: 0012-1606
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SpHnf6, a transcription factor that executes multiple functions in sea urchin embryogenesis Peer-reviewed
O Otim, G Amore, T Minokawa, DR McClay, EH Davidson
DEVELOPMENTAL BIOLOGY 273 (2) 226-243 2004/09
DOI: 10.1016/j.ydbio.2004.05.033
ISSN: 0012-1606
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Expression patterns of four different regulatory genes that function during sea urchin development Peer-reviewed
T Minokawa, JP Rast, C Arenas-Mena, CB Franco, EH Davidson
GENE EXPRESSION PATTERNS 4 (4) 449-456 2004/07
DOI: 10.1016/j.modgep.2004.01.009
ISSN: 1567-133X
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Blastomere isolation and transplantation Invited
Hyla Sweet, Shonan Amemiya, Andrew Ransick, Takuya Minokawa, David R. McClay, Athula Wikramanayake, Ritsu Kuraishi, Masato Kiyomoto, Hiroki Nishida, Jonathan Henry
Methods in Cell Biology 2004 (74) 243-271 2004
ISSN: 0091-679X
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Genetic divergence of two local Japanese populations of the Echinothurioid echinoid, Asthenosoma ijimai
Takuya Minokawa, Shonan Amemiya, Norimasa Matsuoka
Bull. Fac. Agric. & Life Sci. Hirosaki Univ. 5 1-8 2003
Publisher: Hirosaki UniversityISSN: 1344-8897
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A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo Peer-reviewed
EH Davidson, JP Rast, P Oliveri, A Ransick, C Calestani, CH Yuh, T Minokawa, G Amore, Hinman, V, C Arenas-Mena, O Otim, CT Brown, CB Livi, PY Lee, R Revilla, MJ Schilstra, PJC Clarke, AG Rust, ZJ Pan, MI Arnone, L Rowen, RA Cameron, DR McClay, L Hood, H Bolouri
DEVELOPMENTAL BIOLOGY 246 (1) 162-190 2002/06
ISSN: 0012-1606
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New early zygotic regulators expressed in endomesoderm of sea urchin embryos discovered by differential array hybridization Peer-reviewed
A Ransick, JP Rast, T Minokawa, C Calestani, EH Davidson
DEVELOPMENTAL BIOLOGY 246 (1) 132-147 2002/06
ISSN: 0012-1606
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A genomic regulatory network for development Peer-reviewed
EH Davidson, JP Rast, P Oliveri, A Ransick, C Calestani, CH Yuh, T Minokawa, G Amore, Hinman, V, C Arenas-Mena, O Otim, CT Brown, CB Livi, PY Lee, R Revilla, AG Rust, ZJ Pan, MJ Schilstra, PJC Clarke, MI Arnone, L Rowen, RA Cameron, DR McClay, L Hood, H Bolouri
SCIENCE 295 (5560) 1669-1678 2002/03
ISSN: 0036-8075
eISSN: 1095-9203
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Large-scale cDNA analysis of the maternal genetic information in the egg of Halocynthia roretzi for a gene expression catalog of ascidian development Peer-reviewed
KW Makabe, T Kawashima, S Kawashima, T Minokawa, A Adachi, H Kawamura, H Ishikawa, R Yasuda, H Yamamoto, K Kondoh, S Arioka, Y Sasakura, A Kobayashi, K Yagi, K Shojima, Y Kondoh, S Kido, M Tsujinami, N Nishimura, M Takahashi, T Nakamura, M Kanehisa, M Ogasawara, T Nishikata, H Nishida
DEVELOPMENT 128 (13) 2555-2567 2001/07
ISSN: 0950-1991
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Binary specification of nerve cord and notochord cell fates in ascidian embryos Peer-reviewed
T Minokawa, K Yagi, KW Makabe, H Nishida
DEVELOPMENT 128 (11) 2007-2017 2001/06
ISSN: 0950-1991
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A large-scale whole-mount in situ hybridization system: Rapid one-tube preparation of DIG-labeled RNA probes and high throughput hybridization using 96-well silent screen plates Peer-reviewed
M Ogasawara, T Minokawa, Y Sasakura, H Nishida, KW Makabe
ZOOLOGICAL SCIENCE 18 (2) 187-193 2001/03
DOI: 10.2108/zsj.18.187
ISSN: 0289-0003
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Micromere descendants at the blastula stage are involved in normal archenteron formation in sea urchin embryos Peer-reviewed
Y Ishizuka, T Minokawa, S Amemiya
DEVELOPMENT GENES AND EVOLUTION 211 (2) 83-88 2001/02
ISSN: 0949-944X
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Large-scale cDNA analysis of the maternal genetic information in the egg of the ascidian, Halocynthia roretzi, for the gene expression catalog during development. Peer-reviewed
Makabe, K. W, Kawashima, T, Kawashima, S, Minokawa, T, Adachi, A, Kawamura, H, Ishikawa, H, Yasuda, R, Yamamoto, H, Kondoh, K, Arioka, S, Sasakura, Y, Kobayashi, A, Yagi, K, Shojima, K, Kondoh, Y, Kido, S, Tsujinami, M, Nishimura, N, Takahashi, M, Nakamura, T, Kanehisa, M, Ogasawara, M, Nishikata, T, Nishida, H
Development, 128, 2555-2567 2001/01
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Studies on the potential of micromeres to induce archenteron differentiation in embryos of a direct-developing sand dollar, Peronella japonica
M Iijima, Y Ishizuka, T Minokawa, S Amemiya
ZYGOTE 8 S80-S80 2000
ISSN: 0967-1994
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Timing of the potential of micromere-descendants in echinoid embryos to induce endoderm differentiation of mesomere-descendants Peer-reviewed
T Minokawa, S Amemiya
DEVELOPMENT GROWTH & DIFFERENTIATION 41 (5) 535-547 1999/10
DOI: 10.1046/j.1440-169X.1999.00453.x
ISSN: 0012-1592
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Mesodermal cell differentiation in echinoid embryos derived from the animal cap recombined with a quartet of micromeres Peer-reviewed
T Minokawa, S Amemiya
ZOOLOGICAL SCIENCE 15 (4) 541-545 1998/08
DOI: 10.2108/zsj.15.541
ISSN: 0289-0003
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Skeletogenic potential of induced secondary mesenchyme cells derived from the presumptive ectoderm in echinoid embryos Peer-reviewed
T Minokawa, Y Hamaguchi, S Amemiya
DEVELOPMENT GENES AND EVOLUTION 206 (7) 472-476 1997/03
ISSN: 0949-944X
Misc. 4
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ゲノムからみたウニの特徴
美濃川拓哉
生物の科学 遺伝 61 (4) 2007/07/01
Publisher: エヌ・ティー・エス -
A large-scale whole-mount in situ hybridization system: Rapid one-tube preparation of DIG-labeled RNA probes and high throughput hybridization using 96-well silent screen plates (vol 18, pg 187, 2001)
M Ogasawara, T Minokawa, Y Sasakura, H Nishida, KW Makabe
ZOOLOGICAL SCIENCE 18 (3) 443-443 2001/04
ISSN: 0289-0003
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MECHANISM OF BINARY SPECIFICATION OF NOTOCHORD AND NERVE CORD CELL FATES IN ASCIDIAN EMBRYOS(Developmental Biology)Proceedings of the Seventy-First Annual Meeting of the Zoological Society of Japan :
Minokawa T., Nishida H.
Zoological science 17 82-82 2000
Publisher: Zoological Society of JapanISSN: 0289-0003
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A CONVENIENT METHOD OF WHOLE MOUNT IN SITU HYBRIDIZATION (WMISH) FOR COMPREHENSIVE SURVEY OF MULTIPLE cDNA CLONES(Developmental Biology)(Proceedings of the Sixty-Ninth Annual Meeting of the Zoological Society of Japan) :
Minokawa T., Ogasawara M., Sasakura Y., Yamamoto H., Nishida H., Makabe K. W.
Zoological science 15 65-65 1998
Publisher: Zoological Society of JapanISSN: 0289-0003
Books and Other Publications 3
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Atlas of marine invertebrate larvae
Hibino, Taku, Minokawa, Takuya, Amemiya, Shonan (Editors, Boyle, Michael J., Young, Craig M., Sewell, Mary
Academic Press, an imprint of Elsevier,Array 2025/04
ISBN: 9780081028711
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Sea Urchins: Biology, Fishery, and Paleontology
Takuya Minokawa
Tokai University Press 2009/03/05
ISBN: 9784486018100
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Methods in Cell Biology Vol. 74
H. Sweet, S. Amemiya, A. Ransick, T. Minokawa, D.R. McClay, A. Wikramanayake, R. Kuraishi, M. Kiyomoto, H. Nishida, J. Henry
Elsevier Inc. 2004/12
Presentations 10
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Evolution of the micromeres in echinoids International-presentation
Commemorative Symposium for the 27th International Prize for Biology "Genetic Regulation of Development" 2011/11/30
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青森湾に生息するギボ シムシ類(半索動物腸 鰓綱)
浦田慎, 西川輝昭, 阿部広和, 鷲尾正彦
日本動物学会第82回大会 2011/09/21
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ウニ類の「祖先型」幼生 骨片形成機構
山嵜敦子, 木立由美
日本動物学会第82回大会 2011/09/21
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ウニにおける第一卵割 面と幼生前後軸の関係 の多様性
雨宮昭南
日本動物学会第82回大会 2011/09/21
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直接発生ウニ・ヨツアナカシパンの発生メカニズム
第6回 棘皮動物研究集会 2009/12/12
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ウニの発生遺伝子ネットワーク研究の現在と将来
日本動物学会第78回大会 2007/09/20
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Using developmental diversity to study evolution of developmental mechanism International-presentation
The Developmental Biology of the Sea Urchin XVII 2006/09/27
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直接発生型ウニをモデルに発生メカニズムの進化を探る
日本動物学会第77回大会 2006/09/21
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ウニ初期発生メカニズムのゲノム情報を利用した解析
日本発生生物学会第38回大会 2005/06/01
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Cis-regulatory control of SpWnt8 International-presentation
The Developmental Biology of the Sea Urchin. XVI 2005/04
Research Projects 7
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発生機構多様性に関する進化発生生物学的研究 Competitive
System: The Other Research Programs
2005/02 - Present
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間隙棲環形動物に学ぶ生物多様性実習:教材開発と実践
美濃川 拓哉
Offer Organization: 日本学術振興会
System: 科学研究費助成事業
Category: 基盤研究(C)
Institution: 東北大学
2023/04 - 2026/03
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海産クマムシ学への飼育実験系によるアプローチ
藤本 心太, 美濃川 拓哉
Offer Organization: 日本学術振興会
System: 科学研究費助成事業
Category: 基盤研究(C)
Institution: 山口大学
2022/04/01 - 2025/03/31
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Study on the post-embryonic development of the echinoids
Minokawa Takuya
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Category: Grant-in-Aid for Scientific Research (C)
Institution: Tohoku University
2018/04 - 2021/03
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Mechanism of the reorganization of developmental gene regulatory network
MINOKAWA Takuya, YAMAZAKI Atsuko
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
Category: Grant-in-Aid for Scientific Research (C)
Institution: Tohoku University
2010 - 2012
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Evolution of the micromere gene network in sand dollars
YAMAGUCHI Masaaki, MINOKAWA Takuya, WADA Hiroshi
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research
Category: Grant-in-Aid for Scientific Research (C)
Institution: Kanazawa University
2009 - 2011
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An evolutionary study on the transcriptional regulation mechanism in the context of the structural evolution of cis-regulatory region
MINOKAWA Takuya
Offer Organization: Japan Society for the Promotion of Science
System: Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B)
Category: Grant-in-Aid for Young Scientists (B)
Institution: Tohoku University
2006 - 2008
Social Activities 4
Other 6
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箒虫動物の実験動物化と進化発生学研究基盤の確立
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半索動物ギボシムシの神経発生に関する研究
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半索動物ギボシムシの筋肉構成分子に関する研究
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発生様式の多様化に関わる遺伝子ネットワークの研究
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原始的棘皮動物トリノアシの個体発生に関する研究
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直接発生型ウニの発生遺伝子ネットワークの研究