Details of the Researcher

PHOTO

Tomohiro Kaneta
Section
Graduate School of Medicine
Job title
Professor
Degree

  • 博士（医学）（東北大学）

e-Rad No.
50323019

Research History 6

  • 2021/07 - Present
    Tohoku University

  • 2019/04 - 2021/06
    University of Tsukuba

  • 2015/04 - 2019/03
    Yokohama City University School of Medicine Medical Course　Associate Professor

  • 2014/04 - 2015/03
    Tohoku University Cyclotron and Radioisotope Center, Division of Geriatric Behavioral Neurology　Associate Professor

  • 2012/05 - 2014/03
    東北大学病院　放射線診断科　講師

  • 2002/12 - 2012/04
    東北大学病院　放射線診断科　助教

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Committee Memberships 5

  • 日本核医学会　理事

    2021/11 - Present

  • 日本核医学会　評議員

    2011 - Present

  • 日本医学放射線学会　代議員

    2012 - 2021

  • 日本核医学会　編集委員

    2011/10 - 2017/10

  • 日本医学放射線学会　編集委員

    2012 - 2014

Professional Memberships 26

  • 日本医学放射線学会

  • 日本核医学会

  • 米国核医学会(2011/04-2016/03 論文査読者)

  • 日本核医学会(2011/04-2016/03 論文査読者)

  • 日本医学放射線学会(2011/04-2016/03)

  • 米国核医学会(2010/04-2011/03)

  • 日本核医学会(2010/04-2011/03 論文査読者)

  • 日本医学放射線学会(2010/04-2011/03 論文査読者)

  • みちのく核医学の会(2007/04-2015/03 世話人)

  • 日本核医学会(2011/10-2015/10 編集委員)

  • 日本医学放射線学会(2012/06-2014/06 編集委員)

  • 日本医学放射線学会(2012/04-2014/04 評議員)

  • 日本核医学会(2011/05-2013/05 評議員)

  • 日本医学放射線学会

  • 日本核医学会

  • Society of Nuclear Medicine(2011/04-2016/03 )

  • 日本核医学会(2011/04-2016/03 論文査読者)

  • 日本医学放射線学会(2011/04-2016/03)

  • Society of Nuclear Medicine(2010/04-2011/03)

  • 日本核医学会(2010/04-2011/03 論文査読者)

  • 日本医学放射線学会(2010/04-2011/03 論文査読者)

  • みちのく核医学の会(2007/04-2015/03 世話人)

  • 日本核医学会(2011/10-2015/10 編集委員)

  • 日本医学放射線学会(2012/06-2014/06 編集委員)

  • 日本医学放射線学会(2012/04-2014/04 評議員)

  • 日本核医学会(2011/05-2013/05 評議員)

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Research Interests 12

  • Theranostics

  • 分子イメージング

  • PETトレーサー研究

  • PET

  • 腫瘍イメージング

  • Positron Emission Tomography

  • アルツハイマー病

  • アミロイド

  • 画像診断

  • 認知症

  • 核医学

  • 放射線治療

Research Areas 7

  • Life sciences / Pharmaceuticals - chemistry and drug development /

  • Life sciences / Tumor diagnostics and therapeutics /

  • Life sciences / Metabolism and endocrinology /

  • Life sciences / Cognitive neuroscience /

  • Life sciences / Radiology /

  • Life sciences / Psychiatry /

  • Life sciences / Neurology /

Awards 4

  1. 日本核医学会賞

    2020/11

  2. Honorable Mention (Siemens Award)

    2009　Society of Nuclear Medicine

  3. Young Investigator Award

    2001

  4. CUM LAUDE

    2000　欧州核医学会

Papers 108

  1. Optimization of Block Sequential Regularized Expectation Maximization Reconstruction Parameters for Striatal SPECT Using a Ring-Type Semiconductor SPECT/CT System. International-journal

    Nao Yamaguchi, Hayato Odagiri, Hayato Sato, Hiroyasu Kodama, Yoshitaka Tanaka, Takashi Takeuchi, Kentaro Takanami, Akihito Usui, Tomohiro Kaneta

    Journal of nuclear medicine technology　2025/08/26

    DOI： 10.2967/jnmt.125.269869 　

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    This phantom study aimed to optimize the noise-suppression parameter (β) and the edge-preservation parameter (γ) values in the block sequential regularized expectation maximization (BSREM) reconstruction method for 123I-2-β-carbomethoxy-3β-(4-iodophenyl)-N-(3-fluoropropyl)nortropane striatal SPECT using a ring-type cadmium-zinc-telluride camera. Methods: We used a striatum phantom filled with an 123I solution, with adjusted concentrations in the left and right caudate and left and right putamen. The phantom was scanned for 120 min using the StarGuide system, and 20-min SPECT data were extracted from the total acquisition. Using the BSREM method, we generated 42 reconstructed images by varying β and γ. We calculated the percent coefficient of variation and percent contrast for each image. Visual evaluations were conducted by a nuclear medicine physician and 2 technologists. Additionally, we calculated the striatal uptake ratio (SUR) and the ratio of the left caudate SUR to putamen SUR in the left striatum (left striatal ratio). Results: The percent coefficient of variation decreased as the β value increased, whereas percent contrast increased as the γ value increased. We conducted a visual evaluation of 15 reconstructed images selected by physical assessment. Images reconstructed with a β value of 0.03 with a γ value of 5 and those with a β value of 0.05 with a γ value of 10 were deemed suitable for diagnostic purposes because of their accurate depiction of tracer accumulation in each striatal region. SUR and left striatal ratio were comparable for these 2 image sets. Conclusion: Evaluation of the optimal conditions for striatal SPECT imaging with BSREM reconstruction revealed that the optimal β value and γ value combinations were a β value of 0.03 and γ value of 5 and a β value of 0.05 and γ value of 10.

  2. The Utility of a Modified Data-Driven Motion Correction Method Incorporating Computed Tomography Positional Data for Positron Emission Tomography.

    Hayato Odagiri, Hiroshi Watabe, Kentaro Takanami, Nao Yamaguchi, Hirofumi Kawakami, Akie Katsuki, Yoshitaka Tanaka, Takashi Takeuchi, Hiroyasu Kodama, Akihito Usui, Kei Takase, Tomohiro Kaneta

    The Tohoku journal of experimental medicine　2025/06/12

    DOI： 10.1620/tjem.2025.J072 　

  3. The Image Clarity Paradox: Higher CZT SPECT Contrast Does Not Always Translate to Diagnostic Accuracy for Alzheimer's Disease. International-journal

    Kiyotaka Nemoto, Bryan J Mathis, Akemi Iwasaka, Kenjiro Nakayama, Tomohiro Kaneta, Tetsuaki Arai

    Tomography (Ann Arbor, Mich.)　11　(6)　2025/05/25

    DOI： 10.3390/tomography11060061 　

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    Background: Recent advances in single-photon emission computed tomography (SPECT) technology, particularly cadmium-zinc-telluride (CZT) detectors, have improved spatial resolution and contrast in cerebral blood flow imaging. This study aimed to investigate whether these improvements translate to enhanced diagnostic accuracy for Alzheimer's disease (AD). Methods: We compared conventional SPECT (eCAM) with CZT SPECT in 29 patients (mean age 60.9 ± 17.6 years, 69% female) with suspected neurodegenerative diseases. Results: Gray matter/white matter contrast was significantly higher in CZT SPECT compared to eCAM (1.615 ± 0.096 vs. 1.458 ± 0.068, p < 0.001). However, diagnostic accuracy for AD did not improve with CZT SPECT. For the participating psychiatrist, sensitivity decreased from 0.750 (eCAM) to 0.625 (CZT), while for the radiologist, specificity dropped from 0.571 (eCAM) to 0.429 (CZT). Overall accuracy slightly decreased for both readers. Conclusions: These findings suggest that while CZT SPECT offers superior image quality, it may not immediately translate to improved diagnostic accuracy for AD. The study highlights the importance of specialized training for clinicians in interpreting higher-resolution CZT SPECT images to fully leverage their potential in neurodegenerative disease diagnosis. Future research should focus on developing standardized training protocols and larger, multi-center studies to validate these findings.

  4. [Investigation of the Optimal Parameters for Block Sequential Regularized Expectation Maximization (BSREM) Reconstruction in Bone SPECT Using a Ring-type Semiconductor SPECT/CT].

    Hayato Sato, Hayato Odagiri, Nao Yamaguchi, Hiroyasu Kodama, Takashi Takeuchi, Yoshitaka Tanaka, Kentaro Takanami, Akihito Usui, Tomohiro Kaneta

    Nihon Hoshasen Gijutsu Gakkai zasshi　81　(9)　2025

    DOI： 10.6009/jjrt.25-1560 　

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    PURPOSE: This research aims to optimize the block sequential regularized expectation maximization (BSREM) reconstruction in bone single photon emission computed tomography (SPECT) images using a ring-type SPECT/computed tomography (CT) system in terms of image quality and accuracy of quantitative evaluation. METHODS: SPECT images were acquired using a ring-type SPECT/CT and from a SIM2 bone phantom containing a 99m-Tc solution. BSREM parameters were assessed with coefficient of variation (CV), recovery coefficient (RC), contrast noise ratio (CNR), standardized uptake value max (SUVmax), and its root mean square error (RMSESUVmax). Clinical images were reconstructed, and the reconstructions were evaluated as superior based on phantom results. RESULTS: Increasing γ led to higher RC and CV, while increasing β lowered these values. CNR showed no consistent trend. In terms of quantitative evaluation, γ value 5.0, β values 0.3-0.9, and γ value 10, βvalues 0.3-0.9 resulted in lower RMSESUVmax compared to Anger type. Based on the phantom experiment, γ value 5.0, β values 0.5-0.9, and γ value 10, β values 0.7-0.9 were evaluated as superior. Clinical images under these reconstructions, determined from the phantom experiments, with γ value 5.0, β value 0.9, showed the smoothest of normal bone and the clearest separation of neighboring tumors. CONCLUSION: As reconstruction parameters for BSREM reconstruction in bone SPECT on a ring-type semiconductor SPECT/CT system, a γ value of 5.0 and a β value of 0.9 were considered suitable for image quality and quantitative evaluation.

  5. A case report of forensic personal identification by transposed teeth and dental treatment marks using multidetector row computed tomography. International-journal

    Yuka Sasaki, Akihito Usui, Hayato Odagiri, Toshihiko Suzuki, Tomohiro Kaneta, Masato Funayama

    Radiology case reports　19　(2)　581-585　2024/02

    Publisher: Elsevier BV

    DOI： 10.1016/j.radcr.2023.07.068 　

    ISSN： 1930-0433

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    Using postmortem computed tomography (CT) images, we achieved personal identification of a body using transposed teeth and dental treatment marks. Transposition of teeth is a rare malpositioning anomaly. CT images can clarify the malpositioning of the teeth's roots, which is difficult to discern from gross observation of the dentition. Because dental hygiene has reduced the incidence of caries in recent years, it might be difficult to use treatment marks for personal identification in the future. Transposed teeth, although rare, provide an important clue to personal identification.

  6. Verification of the effect of data-driven brain motion correction on PET imaging. International-journal

    Hayato Odagiri, Hiroshi Watabe, Kentaro Takanami, Kazuma Akimoto, Akihito Usui, Hirofumi Kawakami, Akie Katsuki, Nozomu Uetake, Yutaka Dendo, Yoshitaka Tanaka, Hiroyasu Kodama, Kei Takase, Tomohiro Kaneta

    PloS one　19　(7)　e0301919　2024

    DOI： 10.1371/journal.pone.0301919 　

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    INTRODUCTION: Brain positron emission tomography/computed tomography (PET/CT) scans are useful for identifying the cause of dementia by evaluating glucose metabolism in the brain with F-18-fluorodeoxyglucose or Aβ deposition with F-18-florbetaben. However, since imaging time ranges from 10 to 30 minutes, movements during the examination might result in image artifacts, which interfere with diagnosis. To solve this problem, data-driven brain motion correction (DDBMC) techniques are capable of performing motion corrected reconstruction using highly accurate motion estimates with high temporal resolution. In this study, we investigated the effectiveness of DDBMC techniques on PET/CT images using a Hoffman phantom, involving continuous rotational and tilting motion, each expanded up to approximately 20 degrees. MATERIALS AND METHODS: Listmode imaging was performed using a Hoffman phantom that reproduced rotational and tilting motions of the head. Brain motion correction processing was performed on the obtained data. Reconstructed images with and without brain motion correction processing were compared. Visual evaluations by a nuclear medicine specialist and quantitative parameters of images with correction and reference still images were compared. RESULTS: Normalized Mean Squared Error (NMSE) results demonstrated the effectiveness of DDBMC in compensating for rotational and tilting motions during PET imaging. In Cases 1 and 2 involving rotational motion, NMSE decreased from 0.15-0.2 to approximately 0.01 with DDBMC, indicating a substantial reduction in differences from the reference image across various brain regions. In the Structural Similarity Index (SSIM), DDBMC improved it to above 0.96 Contrast assessment revealed notable improvements with DDBMC. In continuous rotational motion, % contrast increased from 42.4% to 73.5%, In tilting motion, % contrast increased from 52.3% to 64.5%, eliminating significant differences from the static reference image. These findings underscore the efficacy of DDBMC in enhancing image contrast and minimizing motion induced variations across different motion scenarios. CONCLUSIONS: DDBMC processing can effectively compensate for continuous rotational and tilting motion of the head during PET, with motion angles of approximately 20 degrees. However, a significant limitation of this study is the exclusive validation of the proposed method using a Hoffman phantom; its applicability to the human brain has not been investigated. Further research involving human subjects is necessary to assess the generalizability and reliability of the presented motion correction technique in real clinical scenarios.

  7. Improvement of Imaging Conditions to Improve the Detection Rate of Head and Neck Cancer by Positron Emission Tomography/Computed Tomography Examination. Peer-reviewed

    Hayato Odagiri, Kentaro Takanami, Tomohiro Kaneta, Akihito Usui, Ikuho Kojima, Hiroyasu Kodama, Shin Saitou, Yoshitaka Tanaka, Yutaka Dendo, Kei Takase

    The Tohoku journal of experimental medicine　260　(2)　141-147　2023/05/30

    DOI： 10.1620/tjem.2023.J026 　

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    Positron emission tomography (PET)/computed tomography (CT) has improved sensitivity and resolution using silicon photomultiplier as a photosensor. Previously, only a fixed setting was available for the shooting time of 1 bed, but now, the shooting time can be changed for each bed. Time can be shortened or extended depending on the target area. A few studies reported on image reconstruction conditions for head and neck cancer in whole-body PET/CT examinations. Thus, this study aimed to optimize the imaging conditions of the head and neck region during whole-body imaging. A cylindrical acrylic container with a 200 mm diameter was used to simulate the head and neck area using a PET/CT system equipped with a semiconductor detector. Spheres of 6-30 mm in diameter were enclosed in the 200 mm diameter cylindrical acrylic vessel. Radioactivity in 18F solution (Hot:BG ratio 4:1) was enclosed in a phantom following the Japanese Society of Nuclear Medicine (JSNM) guidelines. Background radioactivity concentration was 2.53 kBq/mL. List mode acquisition of 1,800 s was collected at 60-1,800 s with the field of view of 700 mm and 350 mm. The image was reconstructed by resizing the matrix to 128 × 128, 192 × 192, 256 × 256, and 384 × 384, respectively. The imaging time per bed in the head and neck should be at least 180 s, and the reconstruction conditions should be a field of view (FOV) of 350 mm, matrix sizes of ≥ 192, and a Bayesian penalized likelihood (BPL) reconstruction with a β-value of 200. This allows detection of > 70% of the 8-mm spheres in the images.

  8. Diagnostic Accuracy of Liver Damage Based on Postmortem Computed Tomography Findings in High-Energy Trauma. Peer-reviewed

    Satsuki Okumura, Akihito Usui, Yusuke Kawasumi, Hayato Odagiri, Masato Funayama, Tomohiro Kaneta

    The Tohoku journal of experimental medicine　257　(4)　327-332　2022/07/22

    DOI： 10.1620/tjem.2022.J046 　

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    The liver is an organ that is frequently injured by blunt trauma. In clinical medicine, contrast-enhanced computed tomography (CT) is useful for diagnosing liver damage. However, detection of liver injury is difficult with postmortem CT (PMCT) that does not use contrast media. This study aims to identify findings that are useful for diagnosing liver injury with PMCT. This study included 97 high-energy trauma cases that underwent both PMCT without contrast and forensic autopsy between July 2009 and November 2020. PMCT findings in and around the liver in cases of liver injury were collected. The diagnostic accuracy of each finding was calculated. Of 97 cases, 62 had liver injury on autopsy. PMCT detected hepatic surface gas in 31 cases, intrahepatic focal gas in 19 cases, high-density fluid accumulation around the liver in 12 cases, and fracture of a right lower (9th-12th) rib in 48 cases. Abnormal PMCT findings in and around the liver had insufficient diagnostic sensitivity, ranging from 19.4% to 38.7%. By contrast, the finding of a right lower rib fracture was more sensitive for suspected liver injury. Our results indicate that abdominal liver findings (hepatic surface gas, intrahepatic focal gas, and high-density fluid accumulation around the liver) are of limited utility for the diagnosis of liver injury, whereas a right lower rib fracture is a useful indirect finding.

  9. Pathological Changes in the Lymphatic System of Patients with Secondary Lower Limb Lymphedema Based on Single Photon-Emission Computed Tomography/Computed Tomography/Lymphoscintigraphy Images. International-journal

    Takahiro Fujiyoshi, Taro Mikami, Koukichi Hashimoto, Saori Asano, Eiko Adachi, Shintaro Kagimoto, Yuichiro Yabuki, Shinya Kitayama, Shinobu Matsubara, Jiro Maegawa, Toshinori Iwai, Atsushi Ishibe, Etsuko Miyagi, Tomohiro Kaneta

    Lymphatic research and biology　20　(2)　144-152　2022/04

    DOI： 10.1089/lrb.2021.0040 　

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    Background: In patients with secondary upper limb lymphedema, positive correlations have been observed between the dermal back flow (DBF) type and visualization of lymph nodes around the clavicle, between the former and the lymph flow pathway type, and between the latter and the visualization of lymph nodes around the clavicle when using single photon-emission computed tomography/computed tomography/lymphoscintigraphy (SPECT-CT LSG). Methods and Results: We analyzed the associations between the visualization of inguinal lymph nodes, the lymph flow pathway type, and the DBF type using SPECT-CT LSG in 81 patients with unilateral secondary lower limb lymphedema by statistical analysis using Fisher's exact test. We revealed that the lymph flow pathways in the lower limb can be classified into nine types because the type in the lower leg is not always equal to the type in the thigh. Associations were observed between the visualization of inguinal lymph nodes and types of DBF (p < 0.01), between the types of lymph flow pathway in the thighs and visualization of the inguinal lymph nodes (p = 0.02), and between the lymph flow pathway types in the thighs and lower legs (p < 0.01). Conclusion: Detriment to the superficial lymph flow pathways in the lower limb appears to usually start from the proximal side, and deep pathways are considered to become dominant from a compensatory perspective as lymphedema severity increases.

  10. Accuracy of virtual monochromatic images generated by the decomposition of photoelectric absorption and Compton scatter in dual-energy computed tomography. International-journal

    Kazuhiro Sato, Chifumi Sato, Ayami Takahashi, Hirokazu Takano, Shingo Kayano, Ayana Ishiguro, Yumi Takane, Tomohiro Kaneta

    Physical and engineering sciences in medicine　45　(1)　239-249　2022/03

    DOI： 10.1007/s13246-022-01107-5 　

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    The decomposition of the linear attenuation coefficient into photoelectric absorption and Compton scattering provides virtual monochromatic images (VMIs). The accuracy of the computed tomography (CT) number of VMI, which is obtained by decomposing the linear attenuation coefficient into photoelectric absorption and Compton scattering, was verified in the energy range of 40-200 keV. The possibility of improving the accuracy of CT numbers by using pre-energy-calibrated images as input was also investigated. The VMIs were generated in two groups of images: (i) dual-energy scanned images and (ii) high- and low-energy images generated by two-material decomposition (i.e., pre-energy-calibrated images). The object for analysis was solid iodine rods inserted in the center of the multi-energy CT phantom. The VMIs were generated from the dual-energy scanned images and pre-energy-calibrated images, and the theoretical and measured CT numbers of solid iodine rods were compared. Furthermore, the absolute error (AE) and relative error (RE) were calculated. With both images, the accuracy of the CT numbers was extremely high for regions close to the high- and low-tube-voltage X-ray energy or the high and low energy of the input images. By using the pre-energy-calibrated images, the maximum AE was reduced from 133 to 96 HU at an energy of 40 keV. Similarly, the maximum RE was reduced from 325 to 50% at an energy of 200 keV. The pre-energy-calibrated images reduced the overall error of the CT numbers and controlled the energy region where accurate CT numbers could be obtained.

  11. Structural brain network correlations with amyloid burden in elderly individuals at risk of Alzheimer's disease. International-journal

    Miho Ota, Yuriko Numata, Ayako Kitabatake, Eriko Tsukada, Tomohiro Kaneta, Takashi Asada, Kohji Meno, Kazuhiko Uchida, Hideaki Suzuki, Tatsumi Korenaga, Tetsuaki Arai

    Psychiatry research. Neuroimaging　319　111415-111415　2022/01

    DOI： 10.1016/j.pscychresns.2021.111415 　

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    Alzheimer's disease (AD) has a long preclinical phase during which beta-amyloid accumulates in the brain without cognitive impairment. However, the pattern of brain network alterations in this early stage of the disease remains to be clarified. In this study we examined the relationships between regional brain network indices and beta-amyloid deposits. Twenty-four elderly subjects with the APOE4 allele underwent both a 1.5-Tesla magnetic resonance imaging (MRI) scan and a positron emission tomography (PET) scan using [18F]Florbetapir. We computed network metrics such as the degree, betweenness centrality, and clustering coefficient, and examined the relationships between the beta-amyloid accumulation and these regional brain network connectivity metrics. We found a significant positive correlation between the global standardized uptake value ratio (SUVR) of [18F]Florbetapir and the betweenness centrality in the left parietal region. However, there were no significant correlations between the SUVR score and other network indices or the regional gray matter volume. Our data suggest a relationship between the beta-amyloid accumulation and the regional brain network connectivity in subjects at risk of AD. The brain connectome may provide an adjunct biomarker for the early detection of AD.

  12. Post-ISCHEMIA Trial Era: Reconsideration of the Role of Nuclear Cardiology in Patients with Chronic Coronary Artery Disease.

    Keisuke Kiso, Atsuro Masuda, Kentaro Takanami, Tomohiro Kaneta, Kei Takase

    Annals of nuclear cardiology　8　(1)　86-90　2022

    DOI： 10.17996/anc.22-00168 　

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    The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial has had a great impact on the management of chronic coronary artery disease (CAD). One of the implications of this trial is the importance of close patient follow-up. To improve patient prognosis, evaluation of the residual extent of ischemia after treatment may be important because several studies have shown a close relationship between residual ischemia and cardiac events. For this assessment, myocardial perfusion single-photon emission computed tomography (MPS) has been utilized and is almost the only modality. Among the participants in the ISCHEMIA trial, more than 10% were excluded due to the absence of obstructive CAD. The pathophysiology of ischemia without non-obstructive coronary artery disease (INOCA) is gaining recognition; however, diagnosis is difficult, except for the assessment of myocardial flow reserve (MFR). Myocardial perfusion positron emission tomography (PET) is the most common modality for noninvasive evaluation of MFR; however, its availability in Japan is limited. For a breakthrough in this situation, a novel gamma camera with a cadmium zinc telluride (CZT) semiconductor might be one of the solutions that enables the evaluation of MFR with a commercially available perfusion tracer, similar to PET. Another solution is a novel PET tracer with a longer half-life. Clinical trials with 18F labeled perfusion agents have been initiated in Japan, and in a few years, delivery of this perfusion tracer will result in more frequent and easier assessment of MFR.

  13. Safety and efficacy of peptide receptor radionuclide therapy with 177Lu-DOTA0-Tyr3-octreotate in combination with amino acid solution infusion in Japanese patients with somatostatin receptor-positive, progressive neuroendocrine tumors.

    Noritoshi Kobayashi, Shoko Takano, Kenichi Ito, Madoka Sugiura, Matsuyoshi Ogawa, Yuma Takeda, Naoki Okubo, Akihiro Suzuki, Motohiko Tokuhisa, Tomohiro Kaneta, Daisuke Utsunomiya, Masaharu Hata, Tomio Inoue, Makoto Hosono, Seigo Kinuya, Yasushi Ichikawa

    Annals of nuclear medicine　35　(12)　1332-1341　2021/12

    DOI： 10.1007/s12149-021-01674-9 　

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    PURPOSE: Peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTA0-Tyr3-octreotate (177Lu-DOTATATE) is one of the most reliable treatments for unresectable, progressive neuroendocrine tumors (NETs) with somatostatin receptor expression. We have, for the first time, reported the results of the tolerability, safety, pharmacokinetics, dosimetry, and efficacy of this treatment for Japanese patients with NET. METHODS: Patients with unresectable, somatostatin receptor scintigraphy (SRS)-positive NETs were enrolled in this phase I clinical trial. They were treated with 29.6 GBq of 177Lu-DOTATATE (four doses of 7.4 GBq) combined with amino acid solution infusion plus octreotide long-acting release (LAR) 30 mg. The primary objective of this study was to evaluate the tolerability, safety, pharmacokinetics, and dosimetry of a single administration of this treatment in patients with SRS-positive NETs. RESULTS: Six Japanese patients (three men and three women; mean age 61.5 years; range 50-70 years) with SRS-positive unresectable NETs were recruited. 177Lu-DOTATATE was eliminated from the blood in a two-phase manner. Cumulative urinary excretion of radioactivity was 60.1% (range 49.0%-69.8%) within the initial 6 h. The cumulative renal absorbed dose for 29.6 GBq of 177Lu-DOTATATE was 16.8 Gy (range 12.0-21.2 Gy), and the biological effective dose was 17.0 Gy (range 12.2-21.5 Gy). Administration of 177Lu-DOTATATE was well tolerated, with no dose-limiting toxicities. Grade 3 lymphopenia occurred in two (33.3%) cases, but there were no other severe toxicities. Four patients achieved partial response (objective response rate, 66.7%), one patient had stable disease, and one patient had progressive disease. CONCLUSION: PRRT with 177Lu-DOTATATE was well-tolerated and showed good outcomes in Japanese patients with unresectable NETs. Peptide receptor radionuclide therapy, 177Lu-DOTA0-Tyr3-octreotate .

  14. Comparison of 18F-FDG PET/CT and 67Ga-SPECT for the diagnosis of fever of unknown origin: a multicenter prospective study in Japan.

    Kazuo Kubota, Noriko Tanaka, Yoko Miyata, Hiroshi Ohtsu, Tadaki Nakahara, Setsu Sakamoto, Takashi Kudo, Yoshihiro Nishiyama, Ukihide Tateishi, Koji Murakami, Yuji Nakamoto, Yasuyuki Taki, Tomohiro Kaneta, Joji Kawabe, Shigeki Nagamachi, Tsuyoshi Kawano, Jun Hatazawa, Youichi Mizutani, Shingo Baba, Kazukuni Kirii, Kunihiko Yokoyama, Terue Okamura, Masashi Kameyama, Ryogo Minamimoto, Junwa Kunimatsu, On Kato, Hiroyuki Yamashita, Hiroshi Kaneko, Satoshi Kutsuna, Norio Ohmagari, Akiyoshi Hagiwara, Yoshimi Kikuchi, Masao Kobayakawa

    Annals of nuclear medicine　35　(1)　31-46　2021/01

    DOI： 10.1007/s12149-020-01533-z 　

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    OBJECTIVE: The aim of this multicenter prospective study was to compare the sensitivity of 18F-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) with that of 67Ga single photon emission computed tomography (SPECT) for the identification of the site of greatest importance for the final diagnosis of the cause of fever of unknown origin (FUO). METHODS: The study participants consisted of patients with an axillary temperature ≥ 38.0 °C on ≥ 2 occasions within 1 week, with repeated episodes for ≥ 2 weeks prior to providing consent, and whose final diagnosis after undergoing specific examinations, including a chest-to-abdomen CT scan, was uncertain. All the patients underwent FDG-PET/CT imaging first, followed by 67Ga-SPECT imaging within 3 days. The results of the FDG-PET/CT and 67Ga-SPECT examinations were reviewed by the central image interpretation committee (CIIC), which was blinded to all other clinical information. The sensitivities of FDG-PET/CT and 67Ga-SPECT were then evaluated with regard to identifying the site of greatest importance for a final diagnosis of the cause of the fever as decided by the patient's attending physician. The clinical impacts (four grades) of FDG-PET/CT and 67Ga-SPECT on the final diagnosis were evaluated. RESULTS: A total of 149 subjects were enrolled in this study between October 2014 and September 2017. No adverse events were identified among the enrolled subjects. Twenty-one subjects were excluded from the study because of deviations from the study protocol. Among the 128 remaining subjects, a final diagnosis of the disease leading to the appearance of FUO was made for 92 (71.9%) subjects. The final diagnoses in these 92 cases were classified into four groups: noninfectious inflammatory disease (52 cases); infectious disease (31 cases), malignancy (six cases); and other (three cases). These 92 subjects were eligible for inclusion in the study's analysis, but one case did not meet the PET/CT image acquisition criteria; thus, PET/CT results were analyzed for 91 cases. According to the patient-based assessments, the sensitivity of FDG-PET/CT (45%, 95% CI 33.1-58.2%) was significantly higher than that for 67Ga-SPECT (25%, 95% CI 15.5-37.5%) (P = 0.0029). The clinical impact of FDG-PET/CT (91%) was also significantly higher than that for 67Ga-SPECT (57%, P < 0.001). CONCLUSIONS: FDG-PET/CT showed a superior sensitivity to 67Ga-SPECT for the identification of the site of greatest importance for the final diagnosis of the cause of FUO.

  15. Feasibility of prognosis assessment for cancer of unknown primary origin using texture analysis of 18F-fluorodeoxyglucose PET/computed tomography images of largest metastatic lymph node. International-journal

    Yoshinobu Ishiwata, Tomohiro Kaneta, Shintaro Nawata, Hitoshi Iizuka, Daisuke Utsunomiya

    Nuclear medicine communications　42　(1)　86-92　2021/01

    DOI： 10.1097/MNM.0000000000001310 　

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    OBJECTIVE: Cancers of unknown primary origin cannot be staged using images, making the prognosis difficult. We attempted to predict prognosis of patients with unknown primary origin using tumour heterogeneity recently introduced in F-fluorodeoxyglucose (F-FDG) PET/computed tomography (CT). METHODS: Overall, 30 patients with unknown primary origin who underwent whole-body F-FDG PET/CT scans were retrospectively enrolled for texture analysis. The volume of interest was placed in the largest metastatic lymph nodes and conventional parameters and grey-level co-occurrence matrix (GLCM) were calculated. Statistical analysis of image-based variables was performed using Cox regression analyses. Patients were stratified into two groups based on cutoff values of GLCMentropy obtained using receiver operating characteristics (ROCs). Patients were analyzed, and overall survival (OS) was compared using Kaplan-Meier analysis. RESULTS: Univariate Cox regression analysis showed significant differences in prognosis for parenchymal organ metastasis (P < 0.01), GLCM homogeneity (P = 0.01), GLCMcontrast (P < 0.01), GLCMentropy (P < 0.01) and GLCMdissimilarity (P < 0.01). Multivariate Cox regression analysis showed a significant difference in reduced prognosis for GLCMentropy positive (P < 0.01). Stratification was performed based on the GLCMentropy cutoff value, determined using ROCs analysis, with smaller groups showing better OS. CONCLUSIONS: Despite previous difficulties in predicting prognosis in patients with unknown primary origin, F-FDG PET/CT texture features may enable stratification of prognosis. This could be useful for appropriate patient selection and management and help identify a subset of patients with favourable outcomes. These novel findings may be helpful for prognostication and improving patient care.

  16. 18FDG-PET imaging and histopathology in neuroleukemiosis with acute myeloid leukemia.

    Yusuke Kiyoki, Ryota Matsuoka, Tomohiro Kaneta, Hidekazu Nishikii

    International journal of hematology　112　(4)　433-434　2020/10

    DOI： 10.1007/s12185-020-02976-w 　

  17. Cardiac Resynchronization Therapy for Improving Non-Uniform Thickening of Left Ventricular Wall: Assessment by Quantitative Gated Myocardial Perfusion SPECT.

    Yuji Wakayama, Makoto Nakano, Koji Fukuda, Koji Kumagai, Yoshinao Sugai, Masanori Hirose, Nobuhiro Yamaguchi, Masateru Kondo, Tomohiro Kaneta, Hiroshi Fukuda, Yutaka Kagaya, Hiroaki Shimokawa

    The Tohoku journal of experimental medicine　251　(2)　69-79　2020/06

    Publisher: Tohoku University Medical Press

    DOI： 10.1620/tjem.251.69 　

    ISSN： 0040-8727

    eISSN： 1349-3329

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    Cardiac resynchronization therapy (CRT) improves cardiac dyssynchrony in heart failure patients with a wide QRS electrocardiogram (ECG). Assessment of left ventricular (LV) dyssynchrony using echocardiography or other imaging modalities is important to predict CRT effectiveness. In this study, we retrospectively evaluated cardiac nuclear imaging of ECG-gated myocardial perfusion single-photon emission computed tomography (SPECT) with 99mTc-sestamibi for CRT candidate (n = 120) with severe heart failure and wide QRS (> 120 msec) in ECG. To analyze LV non-uniformity, we used the quantitative gated SPECT (QGS) software to calculate changes in regional LV wall thickness during a cardiac cycle (i.e., wall thickening scores). Cardiac events (heart failure, ventricular arrhythmias and cardiac death) after CRT during 38 ± 22 (SD) months were also evaluated. In 97 of 120 patients who underwent QGS before and 6 months after CRT, CRT homogenized non-uniform wall thickening between septal and lateral of the LV especially in CRT responders. This observation was indicated as increase in the lateral deflection (XWT) of wall thickening scores before CRT and its decrease after CRT. In 120 patients with QGS before CRT, the larger XWT before CRT (≥ 16.5) predicted better prognoses after CRT. This finding was similarly observed even in patients with narrower baseline QRS (≤ 140 msec; n = 41 of 120), who usually have less benefits from CRT. In conclusion, CRT improved non-uniformity of wall thickening between the LV septal and lateral regions evaluated using QGS, which is predictive of better prognosis in the chronic phase after CRT.

  18. 非小細胞肺癌に対するNivolumab投与後の喀血に対し気管支動脈塞栓術を施行した1例 Peer-reviewed

    石渡 義之, 寺内 幹, 上出 浩之, 飯塚 均, 縄田 晋太郎, 金田 朋洋, 井上 登美夫

    Japanese Journal of Radiology　38　(Suppl.)　13-13　2020/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

    eISSN： 1867-108X

  19. Harmonization of standardized uptake values between two scanners, considering repeatability and magnitude of the values in clinical fluorine-18-fluorodeoxyglucose PET settings: a phantom study. International-journal

    Hitoshi Iizuka, Hiromitsu Daisaki, Matsuyoshi Ogawa, Keisuke Yoshida, Tomohiro Kaneta

    Nuclear medicine communications　40　(8)　857-864　2019/08

    DOI： 10.1097/MNM.0000000000001037 　

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    OBJECTIVE: The standardized uptake value (SUV) is a quantitative imaging biomarker which has been used the most widely in the field of PET. Current harmonization strategies commonly include image blurring by application of an additional extent of post-reconstruction Gaussian filtering in the aim of recovery coefficient adjustment. The objective of this study was to harmonize SUVmax and SUVpeak measured by an older PET/computed tomography scanner with a newer scanner without depending on image blurring. MATERIALS AND METHODS: We performed multiple phantom studies using a count-based method, in which SUVs can be calculated in a repeatable manner. We measured SUVmax and SUVpeak for spheres of various sizes (10, 13, 18, 22, 28, and 37-mm diameter) and actual SUVs (2, 4, 8, and 16) under standard clinical settings. The measured SUVs were compared with the actual SUVs, and the approximate equations were obtained. The relationships of the equations between two different PET/computed tomography scanners, Aquiduo and Celesteion, were examined to obtain conversion equations. RESULTS: The SUVmax and SUVpeak measured by Aquiduo were lower than those measured by Celesteion. For both scanners, the relationships between the actual and measured SUVs were linearly fit (R>0.99) for each sphere size. The equations varied depending on the sphere size. Also, for large spheres (>2 cm), SUVmax and SUVpeak could be harmonized by simple multiplication, regarding the small absolute values of y-intercept (<0.2) as negligible. CONCLUSION: Size-specific equations to convert SUVmax and SUVpeak measured by Aquiduo into the estimated values on Celesteion were obtained. Also, for large lesions (>2 cm), SUVs may be converted by simple multiplication. These methods might enable simple SUV harmonization which is not based on post-reconstruction Gaussian filtering.

  20. Pathological changes in the lymphatic system of patients with secondary upper limb lymphoedema. International-journal

    Taro Mikami, Asumi Koyama, Koukichi Hashimoto, Jiro Maegawa, Yuichiro Yabuki, Shintaro Kagimoto, Shinya Kitayama, Tomohiro Kaneta, Kazunori Yasumura, Shinobu Matsubara, Toshinori Iwai

    Scientific reports　9　(1)　8499-8499　2019/06/11

    DOI： 10.1038/s41598-019-44735-w 　

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    Secondary upper limb lymphoedema is usually caused by lymphatic system dysfunction. Diagnosis is primarily based on clinical features. However, there are no distinct diagnostic criteria for lymphoedema. Although conventional lymphoscintigraphy is a useful technique to diagnose the severity of lymphoedema, the resultant data are two-dimensional. In this study, we examined the pathology of lymphoedema using single photon emission computed tomography-computed tomography lymphoscintigraphy (SPECT-CT LSG), a new technique that provides 3-dimensional information on lymph flow. We observed lymph flow pathways in the subcutaneous and muscle layers of the upper limbs. A significant positive correlation was found between the dermal back flow (DBF) type and the visualization of lymph nodes around the clavicle (p = 0.000266), the type of lymph flow pathways and the visualization of lymph nodes around the clavicle (p = 0.00963), and the DBF type and the lymph flow pathway (p = 0.00766). As the severity of lymphoedema increased, the DBF appeared more distally in the upper limb and the flow into the lymph nodes around the clavicle decreased, whereas the lymph flow pathways in the muscle layer became dominant. These findings demonstrate the features of lymphoedema pathology and the functional anatomy and physiology of the lymphatic system without the need for cadaver dissection.

  21. Early assessment with 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography to predict short-term outcome in clear cell renal carcinoma treated with nivolumab. International-journal Peer-reviewed

    Tadashi Tabei, Noboru Nakaigawa, Tomohiro Kaneta, Ichiro Ikeda, Keiichi Kondo, Kazuhide Makiyama, Hisashi Hasumi, Narihiko Hayashi, Takashi Kawahara, Koji Izumi, Kimito Osaka, Kentaro Muraoka, Jun-Ichi Teranishi, Yasuhide Miyoshi, Yasushi Yumura, Hiroji Uemura, Kazuki Kobayashi, Tomio Inoue, Masahiro Yao

    BMC cancer　19　(1)　298-298　2019/04/02

    DOI： 10.1186/s12885-019-5510-y 　

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    BACKGROUND: We reported previously the usefulness of 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict prognosis of renal cell carcinoma (RCC) treated with molecular targeted agents. Herein we describe a preliminary research of nine patients who underwent FDG-PET/CT before and after initiation of nivolumab. METHODS: Patients with metastatic RCC who were treated by nivolumab from October 2016 to March 2017 were enrolled in this study. All patients underwent FDG-PET/CT at baseline and 1 month as a first response assessment, and contrast-enhanced or non-contrast-enhanced CT scan at 4 month as a second response assessment. Logistic regression analysis was performed to assess the association of potential predictors, including age, gender, baseline diameter, baseline maximum standardized uptake value (SUVmax), lung or not lung metastasis, elevation of SUVmax at 1st assessment, and decrease in diameter at 1st assessment with the response at 2nd assessment (decrease in the diameter ≥ 30% or not). RESULTS: There were 9 patients and 30 lesions. Mean days of first assessment with FDG-PET/CT and second assessment by CT scan from initiation of treatment were 32.3 ± 6.4, 115.5 ± 14.9, respectively. Lesions whose diameter decreased ≥30% at second assessment were defined as responding, and lesions whose diameter did not decrease ≥30% were defined as non-responding. There were 18 responding lesions, and 12 non-responding lesions. We compared change in diameter and SUVmax at first assessment with FDG-PET/CT, respectively. All lesions with decreased diameter and elevated SUVmax at first assessment with FDG-PET/CT showed responding at second assessment by CT scan, while most lesions with increased diameter and declined SUVmax at first assessment showed non-responding at second assessment. The multivariate logistic regression analyses revealed that only the elevation of SUVmax at 1 month was an independent predictor (P = 0.025, OR: 13.087, 95%CI: 1.373-124.716). CONCLUSION: Our findings suggest that the early assessment using FDG-PET/CT can be effective to predict the response of RCC to nivolumab. However, larger prospective studies are needed to confirm these preliminary results. TRIAL REGISTRATION: Registered in University Hospital Medical Information Network in JAPAN [ UMIN0000008141 ], registration date: 11 Jun 2012.

  22. 【神経内分泌腫瘍の薬物療法】神経内分泌腫瘍に対するペプチド受容体放射性核種療法(PRRT)

    小林 規俊, 高野 祥子, 金田 朋洋, 市川 靖史

    腫瘍内科　23　(3)　244-249　2019/03

    Publisher: (有)科学評論社

    ISSN： 1881-6568

  23. 神経内分泌腫瘍におけるソマトスタチン受容体シンチグラフィと病理組織との対比についての検討

    小林 規俊, 高野 祥子, 竹田 雄馬, 徳久 元彦, 廣島 幸彦, 後藤 歩, 金田 朋洋, 井上 登美夫, 市川 靖史

    臨床放射線　64　(3)　267-272　2019/03

    Publisher: 金原出版(株)

    ISSN： 0009-9252

  24. Radio-theranosticsを志向した放射性医薬品開発の現状と展開 Radio-Theranosicsの臨床展開 世界情勢と国内の現状

    高野 祥子, 小林 規俊, 市川 靖史, 上村 博司, 中村 元紀, 堀江 慧一, 安田 尚史, 安藤 賢一, 金田 朋洋, 幡多 政治

    核医学　55　(Suppl.)　S120-S120　2018/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  25. [18F]fluorodeoxyglucose-positron emission tomography study of genetically confirmed patients with Dravet syndrome. International-journal Peer-reviewed

    Haginoya K, Togashi N, Kaneta T, Hino-Fukuyo N, Ishitobi M, Kakisaka Y, Uematsu M, Inui T, Okubo Y, Sato R, Miyabayashi T, Arai A, Ogiwara I, Mazaki E, Yamakawa K, Iinuma K, Kure S

    Epilepsy research　147　9-14　2018/11

    DOI： 10.1016/j.eplepsyres.2018.08.008 　

    ISSN： 0920-1211

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    OBJECTIVE: To understand cerebral brain dysfunction in patients with Dravet syndrome (DS), we conducted a [18F]fluorodeoxyglucose-positron emission tomography (FDG-PET) study in patients with DS whose SCN1A gene variant was confirmed. METHODS: FDG-PET was performed on eight patients with DS. A SCN1A mutation analysis revealed missense variants in four patients and truncation variants in four patients. The patients' ages at the time of the PET study were 2, 2, 2, 3, 6, 13, 20, and 29 years old, respectively. The patients' developmental/intelligence quotient at the time of the PET study were 62, 52, 64, 35, 30, 15, and <25, respectively. The mean standardized uptake value (SUV) was calculated in four segments (frontal, temporal, parietal, and occipital) for the semi-quantitative analysis of 18F-FDG uptake. This value represents the average of the regions of interest in each lobe and was divided by the average SUV of the cerebellar hemisphere of each patient and compared between the patients with DS and the diseased controls. RESULTS: Glucose uptake in patients with DS decreased significantly, particularly in those ≥6 years old. Importantly, a comparison between the younger and older patients with DS revealed that glucose uptake was normal in patients who were ≤3 years (2, 2, 2, and 3 years), whereas a profound reduction in glucose uptake in the fronto-temporo-parietal-occipital cortices was observed in patients ≥ 6 years (6, 13, 20, and 29 years). Magnetic resonance imaging revealed no detectable atrophic legions or other changes in the cerebral cortices of patients ≥ 6 years of age. SIGNIFICANCE: The present study showed a remarkable reduction in cerebral glucose metabolism in multiple lobes for the first time, which became obvious after the late infantile period. These findings may indicate a functional neuroimaging aspect of epileptic encephalopathy of DS or a feature of the SCN1A variant itself.

  26. 特集 膵神経内分泌腫瘍update 10.核医学の膵神経内分泌腫瘍診断･治療への応用

    小林 規俊, 高野 祥子, 金田 朋洋, 市川 靖史

    臨床消化器内科　33　(9)　1161-1168　2018/07/20

    Publisher: 日本メディカルセンター

    DOI： 10.19020/cg.0000000472 　

    ISSN： 0911-601X

    eISSN： 2433-2488

  27. FDG PET/CT after first molecular targeted therapy predicts survival of patients with renal cell carcinoma. International-journal Peer-reviewed

    Noboru Nakaigawa, Keiichi Kondo, Tomohiro Kaneta, Ukihide Tateishi, Ryogo Minamimoto, Kazuhiro Namura, Daiki Ueno, Kazuki Kobayashi, Takeshi Kishida, Ichiro Ikeda, Hisashi Hasumi, Kazuhide Makiyama, Narihiko Hayashi, Kimito Osaka, Kentaro Muraoka, Koji Izumi, Takashi Kawahara, Jun-Ichi Teranishi, Yasuhide Miyoshi, Yasushi Yumura, Hiroji Uemura, Tomio Inoue, Masahiro Yao

    Cancer chemotherapy and pharmacology　81　(4)　739-744　2018/04

    DOI： 10.1007/s00280-018-3542-7 　

    ISSN： 0344-5704

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    PURPOSE: We investigated prospectively whether 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) can predict the overall survival (OS) of patients with advanced renal cell carcinoma (RCC) previously treated by molecular targeted therapies. METHODS: Between 2009 and 2016, 81 patients who had received single molecular targeted therapies (43 sorafenib, 27 sunitinib, 8 temsirolimus and others) and were scheduled for second line molecular targeted therapies for advanced RCC were enrolled in this prospective study. FDG PET/CT was performed after first line molecular targeted therapies, the max SUVmax (highest standardized uptake value for each patient) recorded, and its association with OS compared with those of known risk factors. The median follow-up was 15.4 months (range 0.9-97.4 months). RESULTS: The max SUVmax of the 81 subjects ranged from undetectable to 23.0 (median 7.1). Patients with high max SUVmax had a poor prognosis and multivariate analysis with established risk factors showed that it was an independent predictor of survival (p < 0.001; hazard ratio 1.156; 95% confidence interval 1.080-1.239). Subclassification of patients by max SUVmax showed that the median OS of patients with max SUVmax < 7.0 (39), 7.0-12.0 (30), and ≥ 12.0 (12) were 32.8, 15.2, and 6.0 months, respectively. These differences are statistically significant (< 7.0 versus 7.0-12.0: p = 0.0333, 7.0-12.0 versus ≥ 12.0: p = 0.0235). CONCLUSIONS: The max SUVmax by FDG PET/CT of patients with RCC evaluated after their first molecular targeted therapy predicts OS. FDG PET/CT is a useful "imaging biomarker" for patients with advanced RCC planning sequential molecular targeted therapies.

  28. Use of count-based image reconstruction to evaluate the variability and repeatability of measured standardised uptake values Peer-reviewed

    Tomohiro Kaneta, Hiromitsu Daisaki, Matsuyoshi Ogawa, En-Tao Liu, Hitoshi Iizuka, Tetsu Arisawa, Ayako Hino-Shishikura, Keisuke Yoshida, Tomio Inoue

    PLoS ONE　13　(2)　e0192549　2018/02/01

    Publisher: Public Library of Science

    DOI： 10.1371/journal.pone.0192549 　

    ISSN： 1932-6203

  29. 【膵神経内分泌腫瘍診療の最前線】膵神経内分泌腫瘍に対する111Inペンテトレオチドを用いたソマトスタチン受容体シンチグラフィー(SRS)の有用性と今後の展開

    小林 規俊, 高野 祥子, 金田 朋洋, 徳久 元彦, 後藤 歩, 遠藤 格, 井上 登美夫, 市川 靖史

    胆と膵　38　(12)　1371-1377　2017/12

    Publisher: 医学図書出版(株)

    ISSN： 0388-9408

  30. Prognostic value of volumetric FDG PET/CT parameters in patients with oral tongue squamous cell carcinoma who were treated by superselective intra-arterial chemoradiotherapy Peer-reviewed

    Satoko Suzuki-Shibata, Yayoi Yamamoto, Tetsuo Yoshida, Nobutaka Mizoguchi, Tetsuo Nonaka, Akira Kubota, Hiroto Narimatsu, Yohei Miyagi, Toshiaki Kobayashi, Tomohiro Kaneta, Tomio Inoue

    JAPANESE JOURNAL OF RADIOLOGY　35　(12)　740-747　2017/12

    DOI： 10.1007/s11604-017-0686-z 　

    ISSN： 1867-1071

    eISSN： 1867-108X

  31. Topics of nuclear medicine research in Europe Peer-reviewed

    Masayuki Inubushi, Tomohiro Kaneta, Takayoshi Ishimori, Etsuko Imabayashi, Atsutaka Okizaki, Naohiko Oku

    ANNALS OF NUCLEAR MEDICINE　31　(8)　571-574　2017/10

    DOI： 10.1007/s12149-017-1198-8 　

    ISSN： 0914-7187

    eISSN： 1864-6433

  32. Initial evaluation of the Celesteion large-bore PET/CT scanner in accordance with the NEMA NU2-2012 standard and the Japanese guideline for oncology FDG PET/CT data acquisition protocol version 2.0 Peer-reviewed

    Tomohiro Kaneta, Matsuyoshi Ogawa, Nobutoku Motomura, Hitoshi Iizuka, Tetsu Arisawa, Ayako Hino-Shishikura, Keisuke Yoshida, Tomio Inoue

    EJNMMI RESEARCH　7　(1)　83　2017/10

    DOI： 10.1186/s13550-017-0331-y 　

    ISSN： 2191-219X

  33. 内用療法の普及と安全利用～多職種の立場から～ 新規RI内用療法薬剤の導入と多職種連携 当院の取り組み

    高野 祥子, 杉浦 円, 高田 由貴, 有澤 哲, 金田 朋洋, 幡多 政治, 小林 規俊, 市川 靖史, 尾川 松義, 臼井 淳之, 大沼 教子, 立石 由佳, 木藤 理恵, 山中 竹春, 井上 登美夫

    核医学　54　(Suppl.)　S65-S65　2017/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  34. 神経内分泌腫瘍におけるソマトスタチン受容体シンチグラフィーと病理組織との対比についての検討

    小林 規俊, 徳久 元彦, 後藤 歩, 高野 祥子, 金田 朋洋, 井上 登美夫, 市川 靖史

    核医学　54　(Suppl.)　S171-S171　2017/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  35. Head-to-Head Visual Comparison between Brain Perfusion SPECT and Arterial Spin-Labeling MRI with Different Postlabeling Delays in Alzheimer Disease Peer-reviewed

    T. Kaneta, O. Katsuse, T. Hirano, M. Ogawa, K. Yoshida, T. Odawara, Y. Hirayasu, T. Inoue

    AMERICAN JOURNAL OF NEURORADIOLOGY　38　(8)　1562-1568　2017/08

    DOI： 10.3174/ajnr.A5238 　

    ISSN： 0195-6108

    eISSN： 1936-959X

  36. Quantification of temporal changes in calcium score in active atherosclerotic plaque in major vessels by F-18-sodium fluoride PET/CT Peer-reviewed

    Yoshinobu Ishiwata, Tomohiro Kaneta, Shintaro Nawata, Ayako Hino-Shishikura, Keisuke Yoshida, Tomio Inoue

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　44　(9)　1529-1537　2017/08

    DOI： 10.1007/s00259-017-3680-x 　

    ISSN： 1619-7070

    eISSN： 1619-7089

  37. One-month assessment of renal cell carcinoma treated by everolimus using FDG PET/CT predicts progression-free and overall survival. International-journal Peer-reviewed

    Hiroki Ito, Keiichi Kondo, Takashi Kawahara, Tomohiro Kaneta, Ukihide Tateishi, Daiki Ueno, Kazuhiro Namura, Kazuki Kobayashi, Yasuhide Miyoshi, Yasushi Yumura, Kazuhide Makiyama, Narihiko Hayashi, Hisashi Hasumi, Kimito Osaka, Yumiko Yokomizo, Jun-Ichi Teranishi, Yusuke Hattori, Tomio Inoue, Hiroji Uemura, Masahiro Yao, Noboru Nakaigawa

    Cancer chemotherapy and pharmacology　79　(5)　855-861　2017/05

    DOI： 10.1007/s00280-017-3275-z 　

    ISSN： 0344-5704

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    PURPOSE: We evaluated 18F-2-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG PET/CT) results as outcome predictors for patients with metastatic renal cell carcinoma (RCC) treated by everolimus (EVL), an inhibitor of mammalian target of rapamycin. METHODS: We retrospectively reviewed 30 patients who were treated with EVL for metastatic RCC between May 2010 and March 2015, by evaluating their FDG PET/CT result before and 1 month after starting EVL treatment. We examined the relationships between each patient's maximum standardized uptake value (max SUVmax) assessed by FDG PET/CT on progression-free survival (PFS) and overall survival (OS). RESULTS: Median PFS for all 30 patients was 3.77 months (range 0.72-24.56 months) and median OS after EVL treatment of all 30 patients was 11.67 months (range 1.0-62.98 months). Enrolled patients were divided into two groups by max SUVmax prior to EVL (median = 7.6) and at 1 month after EVL treatment (median = 5.7). PFS were significantly shorter in higher max SUVmax prior to EVL (<7.6, PFS 7.8 vs 3.5 months, log-rank P = 0.017) and at 1 month after EVL (<5.7, PFS 10.6 vs 2.7 months, log-rank P = 0.002) than lower max SUVmax. OS were also significantly shorter in higher max SUVmax prior to EVL (<7.6, OS 18.1 vs 7.5 months, log-rank P = 0.010) and at 1 month after EVL (<5.7, OS 17.2 vs 7.5 months, log-rank P = 0.009) than lower max SUVmax. Multivariate Cox hazard regression analysis indicated that max SUVmax at 1 month after EVL is an independent predictor of both PFS and OS in patients treated with EVL although univariate regression analysis showed max SUVmax before EVL is a possible predictor. CONCLUSIONS: Max SUVmax assessed by FDG PET/CT prior to EVL and at 1 month after EVL treatment can accurately predict PFS and can guide decisions on whether to continue or change treatments for patients with EVL-treated RCC who suffer from adverse events.

  38. Voxel-wise correlations between cognition and cerebral blood flow using arterial spin-labeled perfusion MRI in patients with Alzheimer's disease: a cross-sectional study Peer-reviewed

    Tomohiro Kaneta, Omi Katsuse, Takamasa Hirano, Matsuyoshi Ogawa, Ayako Shihikura-Hino, Keisuke Yoshida, Toshinari Odawara, Yoshio Hirayasu, Tomio Inoue

    BMC NEUROLOGY　17　(1)　91　2017/05

    DOI： 10.1186/s12883-017-0870-x 　

    ISSN： 1471-2377

  39. 膵・消化管神経内分泌腫瘍の診断と治療 NET診療におけるオクトレオスキャンとPRRTの役割、今後の展望

    小林 規俊, 徳久 元彦, 後藤 歩, 高野 祥子, 金田 朋洋, 井上 登美夫, Guillaume Nicolas, Damian Wild, 市川 靖史

    日本内分泌・甲状腺外科学会雑誌　34　(Suppl.1)　S67-S67　2017/04

    Publisher: 日本内分泌外科学会・日本甲状腺外科学会

    ISSN： 2186-9545

  40. Surgery-based versus radiation-based treatment strategy for a high metabolic volume laryngeal cancer Peer-reviewed

    Kenichiro Yabuki, Daisuke Sano, Osamu Shiono, Yasuhiro Arai, Yoshihiro Chiba, Teruhiko Tanabe, Goshi Nishimura, Masahiro Takahashi, Takahide Taguchi, Tomohiro Kaneta, Masaharu Hata, Nobuhiko Oridate

    LARYNGOSCOPE　127　(4)　862-867　2017/04

    DOI： 10.1002/lary.26233 　

    ISSN： 0023-852X

    eISSN： 1531-4995

  41. Evaluation of the Response to Breast Cancer Neoadjuvant Chemotherapy Using 18F-FDG Positron Emission Mammography Compared With Whole-Body 18F-FDG PET: A Prospective Observational Study. International-journal Peer-reviewed

    Mutsumi Noritake, Kazutaka Narui, Tomohiro Kaneta, Sadatoshi Sugae, Kentaro Sakamaki, Tomio Inoue, Takashi Ishikawa

    Clinical nuclear medicine　42　(3)　169-175　2017/03

    DOI： 10.1097/RLU.0000000000001497 　

    ISSN： 0363-9762

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    PURPOSE: The aim of this study was to assess therapeutic response to breast cancer neoadjuvant chemotherapy (NAC) by F-FDG positron emission mammography (PEM) compared with that to whole-body F-FDG PET (WBPET). METHODS: Twenty patients underwent WBPET and PEM 3 times: the first time was before NAC, the second time was after 2 courses of NAC, and the third time was after all courses of NAC. A pathological complete response (pCR) was defined as no evidence of residual invasive cancer with or without ductal carcinoma in situ. The relationships between each modality's SUVmax and pathological response were evaluated. RESULTS: Nine patients achieved a pCR, whereas the other 11 patients had a non-pCR. The SUVmax of WBPET after 2 courses of NAC was significantly lower in the pCR group than in the non-pCR group (1.4 ± 0.4 vs 2.7 ± 2.1, P = 0.0334). There were no significant differences in the SUVmax of PEM (ie, PEM uptake value [PUV]) between the groups. The SUVmax of WBPET (area under the ROC curve [AUC] = 0.761) was superior to the PUVmax (AUC, 0.648) for predicting non-pCR at the interim time point. After all courses of chemotherapy, there were no significant differences between the groups in the SUVmax of WBPET; however, PUVmax was significantly lower in the pCR group than in the non-pCR group (1.0 ± 0.2 vs 2.5 ± 2.7, P = 0.0351). After NAC, the PUVmax (AUC, 0.796) was superior to the SUVmax of WBPET (AUC, 0.671). CONCLUSIONS: There proved to be no apparent superiority of PEM in predicting pCR at the interim time point. Positron emission mammography had greater diagnostic capability for detecting residual cancer after all courses of NAC.

  42. Recent developments with large-bore PET/CT Peer-reviewed

    Tomohiro Kaneta, Tomio Inoue

    Personalized Pathway-Activated Systems Imaging in Oncology: Principal and Instrumentation　185-194　2017/01/01

    Publisher: Springer Singapore

    DOI： 10.1007/978-981-10-3349-0_10 　

  43. Development of a double-stranded siRNA labelling method by using Tc-99m and single photon emission computed tomography imaging Peer-reviewed

    Daisuke Kano, Yoshihiro Nakagami, Hiroaki Kurihara, Shota Hosokawa, Sadamoto Zenda, Masahiko Kusumoto, Hirofumi Fujii, Tomohiro Kaneta, Shinichiro Saito, Yoshihiro Uesawa, Hajime Kagaya

    JOURNAL OF DRUG TARGETING　25　(2)　172-178　2017

    DOI： 10.1080/1061186X.2016.1223675 　

    ISSN： 1061-186X

    eISSN： 1029-2330

  44. The acceleration of glucose accumulation in renal cell carcinoma assessed by FDG PET/CT demonstrated acquisition of resistance to tyrosine kinase inhibitor therapy Peer-reviewed

    Noboru Nakaigawa, Keiichi Kondo, Daiki Ueno, Kazuhiro Namura, Kazuhide Makiyama, Kazuki Kobayashi, Koichi Shioi, Ichiro Ikeda, Takeshi Kishida, Tomohiro Kaneta, Ryogo Minamimoto, Ukihide Tateishi, Tomio Inoue, Masahiro Yao

    BMC CANCER　17　(1)　39　2017/01

    DOI： 10.1186/s12885-016-3044-0 　

    ISSN： 1471-2407

  45. Differences in sodium fluoride-18 uptake in the normal skeleton depending on the location and characteristics of the bone Peer-reviewed

    Shintaro Nawata, Tomohiro Kaneta, Matsuyoshi Ogawa, Yoshinobu Ishiwata, Naomi Kobayashi, Ayako Shishikura-Hino, Keisuke Yoshida, Yutaka Inaba, Tomoyuki Saito, Tomio Inoue

    NUKLEARMEDIZIN-NUCLEAR MEDICINE　56　(3)　91-96　2017

    DOI： 10.3413/Nukmed-0867-16-12 　

    ISSN： 0029-5566

  46. Clinical Usefulness of Somatostatin Receptor Scintigraphy in Japanese Patients with Gastroenteropancreatic Neuroendocrine Tumors Peer-reviewed

    Sho Hasegawa, Noritoshi Kobayashi, Motohiko Tokuhisa, Ayumu Goto, Shoko Takano, Yuuki Takada, Tomohiro Kaneta, Ryutaro Mori, Ryusei Matsuyama, Itaru Endo, Shoji Yamanaka, Atsushi Nakajima, Tomio Inoue, Yasushi Ichikawa

    DIGESTION　96　(1)　13-20　2017

    DOI： 10.1159/000470838 　

    ISSN： 0012-2823

    eISSN： 1421-9867

  47. Variation and repeatability of measured standardized uptake values depending on actual values: a phantom study. Peer-reviewed

    Kaneta T, Sun N, Ogawa M, Iizuka H, Arisawa T, Hino-Shishikura A, Yoshida K, Inoue T

    American journal of nuclear medicine and molecular imaging　7　(5)　204-211　2017

  48. Prognostic significance of metabolic tumor volume in patients with piriform sinus carcinoma treated by radiotherapy with or without concurrent chemotherapy. International-journal Peer-reviewed

    Kenichiro Yabuki, Daisuke Sano, Osamu Shiono, Yasuhiro Arai, Hideaki Takahashi, Yoshihiro Chiba, Teruhiko Tanabe, Goshi Nishimura, Masahiro Takahashi, Takahide Taguchi, Tomohiro Kaneta, Masaharu Hata, Nobuhiko Oridate

    Head & neck　38　(11)　1666-1671　2016/11

    DOI： 10.1002/hed.24488 　

    ISSN： 1043-3074 1097-0347

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    BACKGROUND: The purpose of this study was to elucidate the prognostic significance of the pretreatment metabolic tumor volume (MTV) in patients with piriform sinus carcinoma treated by radiation-based therapy. METHODS: This retrospective study included 100 patients with piriform sinus carcinomas who had received treatment by radiation-based therapy. The MTV values were obtained from pretreatment positron emission tomography (PET). The association between clinical factors, including the MTV, and survival was analyzed. RESULTS: Kaplan-Meier estimates revealed the 5-year disease-free survival (DFS) rates were significantly poorer for patients with a high MTV compared to those with a low MTV. In the multivariate analysis, MTV (p < .001), nodal metastasis (p = .011), and applied chemotherapy regimen (p = .004) were found to be independent prognostic factors for DFS. CONCLUSION: The locoregional MTV is a prognostic factor for DFS in patients with piriform sinus carcinoma treated by radiation-based therapy. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1708-1716, 2016.

  49. Pharmacokinetics of single dose radium-223 dichloride (BAY 88-8223) in Japanese patients with castration-resistant prostate cancer and bone metastases Peer-reviewed

    Keisuke Yoshida, Tomohiro Kaneta, Shoko Takano, Madoka Sugiura, Tsuyoshi Kawano, Ayako Hino, Tou Yamamoto, Kazuya Shizukuishi, Masato Kaneko, Christian Zurth, Tomio Inoue

    ANNALS OF NUCLEAR MEDICINE　30　(7)　453-460　2016/08

    DOI： 10.1007/s12149-016-1093-8 　

    ISSN： 0914-7187

    eISSN： 1864-6433

  50. ちょっと気になる胆・膵画像 ティーチングファイルから(第32回) 膵神経内分泌腫瘍、多発肝転移術後再発に対しソマトスタチン受容体シンチグラフィーが施行された1例

    丹内 啓允, 高野 祥子, 小林 規俊, 市川 靖史, 金田 朋洋, 井上 登美夫

    胆と膵　37　(3)　205-207　2016/03

    Publisher: 医学図書出版(株)

    ISSN： 0388-9408

  51. FDG-PET study of patients with Leigh syndrome Peer-reviewed

    Kauzhiro Haginoya, Tomohiro Kaneta, Noriko Togashi, Naomi Hino-Fukuyo, Tomoko Kobayashi, Mitsugu Uematsu, Taro Kitamura, Takehiko Inui, Yukimune Okubo, Yusuke Takezawa, Mai Anzai, Wakaba Endo, Noriko Miyake, Hirotomo Saitsu, Naomichi Matsumoto, Shigeo Kure

    JOURNAL OF THE NEUROLOGICAL SCIENCES　362　309-313　2016/03

    DOI： 10.1016/j.jns.2016.02.008 　

    ISSN： 0022-510X

    eISSN： 1878-5883

  52. FDG PET/CT as a prognostic biomarker in the era of molecular-targeting therapies: max SUVmax predicts survival of patients with advanced renal cell carcinoma. International-journal Peer-reviewed

    Noboru Nakaigawa, Keiichi Kondo, Ukihide Tateishi, Ryogo Minamimoto, Tomohiro Kaneta, Kazuhiro Namura, Daiki Ueno, Kazuki Kobayashi, Takeshi Kishida, Ichiro Ikeda, Hisashi Hasumi, Kazuhide Makiyama, Yoshinobu Kubota, Tomio Inoue, Masahiro Yao

    BMC cancer　16　67-67　2016/02/08

    DOI： 10.1186/s12885-016-2097-4 　

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    BACKGROUND: Various molecular-targeting therapies have become available for the treatment of advanced renal cell carcinoma (RCC). Accurate prognostication is desirable for choosing the appropriate treatment for individual patients. (18)F-2-fluoro-2-deoxyglucose positron-emission tomography/computed tomography (FDG PET/CT) is a non-invasive tool for evaluating glucose accumulation, which can be an index of biological characteristics of cancer. We prospectively evaluated FDG PET/CT as a prognostic indicator in patients with advanced RCC. METHODS: A total of 101 patients slated for different systematic therapies for advanced RCC were enrolled between 2008 and 2014. A total of 61 patients had recurrent RCC (58 metastatic and 3 regional) and 40 patients had stage IV RCC (36 metastatic and 4 locoregional). Sixteen patients had not undergone nephrectomy. Pre-treatment FDG PET/CT was performed, and the max SUVmax (the highest SUV measurement in each patient) was recorded. The max SUVmax was compared with different clinical risk factors as prognostic indicators. The median observation period was 18 months (range 1-70 months). RESULTS: The max SUVmax of the 101 subjects ranged from undetectable to 23.0 (median 6.9). Patients with high max SUVmax had a poor prognosis. Multivariate analysis with standard risk factors revealed that max SUVmax was an independent predictor of survival (p < 0.001; hazard ratio 1.265; 95% confidence interval 1.159-1.380). A cutoff of 8.8 for max SUVmax advocated in our previous report was highly significant (p < 0.0001). When we subclassified the max SUVmax values, the median overall survival of subjects with max SUVmax < 7.0 was 41.9 months. That of subjects with max SUVmax between 7.0 and 12.0 was 20.6 months. That of subjects with max SUVmax ≥ 12.0 was 4.2 months. The differences were statistically significant. CONCLUSIONS: Pretreatment max SUVmax assessed by FDG PET/CT is a useful prognostic marker for patients with advanced RCC, providing helpful information for clinical decision making.

  53. Decreased Physical Activity Associated with Executive Dysfunction Correlates with Cognitive Impairment among Older Adults in the Community: A Retrospective Analysis from the Kurihara Project Peer-reviewed

    Yoritoshi Kobayashi, Yumi Takahashi, Takashi Seki, Tomohiro Kaneta, Kenichi Amarume, Mari Kasai, Kenichi Meguro

    Dementia and Geriatric Cognitive Disorders Extra　6　(2)　350-360　2016

    Publisher: S. Karger AG

    DOI： 10.1159/000448027 　

    ISSN： 1664-5464

  54. SUV measurement of normal vertebrae using SPECT/CT with Tc-99m methylene diphosphonate. International-journal Peer-reviewed

    Tomohiro Kaneta, Matsuyoshi Ogawa, Hiromitsu Daisaki, Shintaro Nawata, Keisuke Yoshida, Tomio Inoue

    American journal of nuclear medicine and molecular imaging　6　(5)　262-268　2016

    ISSN： 2160-8407

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    The purpose of this study is to perform quantitative measurement based on the standardized uptake value (SUV) of the uptake of Tc-99m methylene diphosphonate (MDP) in the normal vertebrae using a single photon emission tomography (SPECT)/computed tomography (CT) scanner. A retrospective study of patients with cancer or joint disorders was performed. We acquired data for a group of 29 patients (8 women and 21 men; mean age, 68.2 ± 6.7 years; age range, 44-87 years) undergoing bone SPECT/CT scans with Tc-99m MDP between September and October 2015. Various SUVs were calculated based on body-weight, lean-body-weight (lbw), Japanese lean-body-weight (jlbw) and Japanese bone-mineral-content (jbmc). SUVs of normal vertebrae showed a wide range of values. Among these, the maximum body-weight based SUV showed the lowest coefficient of variation. The SUVs also showed relatively small intra-subject variability. In addition, all SUVs showed moderate and significant correlation with height. Moreover, lbw-, jlbw-, and jbmc-based SUVs of men were significantly higher than those of women. In conclusions, SUVs of normal vertebrae showed a relatively large inter-individual variability and small intra-individual variability. As a quantitative imaging biomarker, SUVs might require standardization with adequate reference data for the same subject to minimize variability.

  55. Improved Diagnostic Accuracy of SPECT Through Statistical Analysis and the Detection of Hot Spots at the Primary Sensorimotor Area for the Diagnosis of Alzheimer Disease in a Community-Based Study "The Osaki-Tajiri Project" Peer-reviewed

    Tomohiro Kaneta, Masahiro Nakatsuka, Kei Nakamura, Takashi Seki, Satoshi Yamaguchi, Masahiro Tsuboi, Kenichi Meguro

    CLINICAL NUCLEAR MEDICINE　41　(1)　e1-e6　2016/01

    DOI： 10.1097/RLU.0000000000000976 　

    ISSN： 0363-9762

    eISSN： 1536-0229

  56. FDG-PET/CTで経過を追跡できた透析アミロイドーシスの1例

    渡邉 亮輔, 川野 剛, 金田 朋洋, 井上 登美夫

    核医学　52　(4)　390-390　2015/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  57. Formula corrected maximal standardized uptake value in FDG-PET for partial volume effect and motion artifact is not a prognostic factor in stage I non-small cell lung cancer treated with stereotactic body radiotherapy Peer-reviewed

    Takaya Yamamoto, Noriyuki Kadoya, Yuko Shirata, Tomohiro Kaneta, Masashi Koto, Rei Umezawa, Youjirou Ishikawa, Masaki Kubozono, Toshiyuki Sugawara, Haruo Matsushita, Keiko Abe, Ken Takeda, Keiichi Jingu

    ANNALS OF NUCLEAR MEDICINE　29　(8)　666-673　2015/10

    DOI： 10.1007/s12149-015-0991-5 　

    ISSN： 0914-7187

    eISSN： 1864-6433

  58. Clinical values of FDG PET in polymyositis and dermatomyositis syndromes: imaging of skeletal muscle inflammation Peer-reviewed

    Maki Tateyama, Kazuo Fujihara, Tatsuro Misu, Akira Arai, Tomohiro Kaneta, Masashi Aoki

    BMJ OPEN　5　(1)　e006763　2015

    DOI： 10.1136/bmjopen-2014-006763 　

    ISSN： 2044-6055

  59. Pitfalls of Voxel-Based Amyloid PET Analyses for Diagnosis of Alzheimer's Disease: Artifacts due to Non-Specific Uptake in the White Matter and the Skull Peer-reviewed

    Akira Arai, Tomohiro Kaneta, Nobuyuki Okamura, Manabu Tashiro, Ren Iwata, Kentaro Takanami, Hiroshi Fukuda, Shoki Takahashi, Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai

    TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE　234　(3)　175-181　2014/11

    DOI： 10.1620/tjem.234.175 　

    ISSN： 0040-8727

    eISSN： 1349-3329

  60. Assessment of Myocardial Metabolic Disorder Associated With Mediastinal Radiation Therapy for Esophageal Cancer Peer-reviewed

    Umezawa, R. Takanami, K. Ota, H. Kaneta, T. Kadoya, N. Fujita, Y. Arai, A. Arai, K. Matsushita, H. Takase, K. Jingu, K

    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS　90　(1)　S205-S205　2014/09/01

    DOI： 10.1186/s13014-015-0410-z 　

    eISSN： 1748-717X

  61. Analysis of early phase [C-11]BF-227 PET, and its application for anatomical standardization of late-phase images for 3D-SSP analysis Peer-reviewed

    Tomohiro Kaneta, Nobuyuki Okamura, Akira Arai, Kentaro Takanami, Katsutoshi Furukawa, Manabu Tashiro, Shozo Furumoto, Ren Iwata, Shoki Takahashi, Hiroyuki Arai, Kazuhiko Yanai, Yukitsuka Kudo

    JAPANESE JOURNAL OF RADIOLOGY　32　(3)　138-144　2014/03

    DOI： 10.1007/s11604-013-0276-7 　

    ISSN： 1867-1071

    eISSN： 1867-108X

  62. 呼吸性移動によるSUVmaxの減弱に対する補正法の検討

    角谷倫之, 藤田幸男, 山本貴也, 白田佑子, 阿部恵子, 梅澤玲, 久保園正樹, 菅原俊幸, 松下晴雄, 神宮啓一, 土橋卓, 武田 賢, 金田朋洋

    Japanese Journal of Radiology　32　7-7　2014/02

  63. Characterization of lipid-rich adrenal tumors by FDG PET/CT: Are they hormone-secreting or not? Peer-reviewed

    Kentaro Takanami, Tomohiro Kaneta, Ryo Morimoto, Fumitoshi Satoh, Yasuhiro Nakamura, Kei Takase, Shoki Takahashi

    ANNALS OF NUCLEAR MEDICINE　28　(2)　145-153　2014/02

    DOI： 10.1007/s12149-013-0793-6 　

    ISSN： 0914-7187

    eISSN： 1864-6433

  64. Evidence for Brain Activation in Patients With Takotsubo Cardiomyopathy Peer-reviewed

    Hideaki Suzuki, Yasuharu Matsumoto, Tomohiro Kaneta, Koichiro Sugimura, Jun Takahashi, Yoshihiro Fukumoto, Shoki Takahashi, Hiroaki Shimokawa

    CIRCULATION JOURNAL　78　(1)　256-258　2014/01

    DOI： 10.1253/circj.CJ-13-1276 　

    ISSN： 1346-9843

    eISSN： 1347-4820

  65. Reassessing the Prognostic Value of the Maximum Standardized Uptake Value (SUVmax) in FDG-PET by Correcting for the Partial Volume Effect and Respiratory Motion Blur in Stage I Non-Small Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy Peer-reviewed

    T. Yamamoto, N. Kadoya, Y. Shirata, R. Umezawa, M. Kubozono, T. Sugawara, T. Kaneta, H. Matsushita, K. Takeda, K. Jingu

    Int J Radiat Oncol Biol Phys　87　(2)　S523-S523　2013/10

  66. Magnetic Resonance Imaging Findings of Radiation-Induced Myocardial Damage in Patients With Esophageal Cancer Peer-reviewed

    R. Umezawa, K. Jingu, K. Takase, H. Ota, K. Takanami, T. Kaneta, K. Takeda, H. Matsushita, S. Takahashi

    Int J Radiat Oncol Biol Phys　87　(2)　S291-S292　2013/10

  67. Investigation of correction method of recovery effect and motion blur for SUV quantification in FDG PET/CT in patients with early lung cancer Peer-reviewed

    Noriyuki Kadoya, Yukio Fujita, Kengo Ito, Suguru DObashi, Ken Takeda, Kazuma Kishi, Takaya Yamamoto, Rei Umezawa, Toshiyuki Sugawara, Tomohiro Kaneta, Haruo Matsushita, Keiichi Jingu

    J Nucl Med Radiat Ther　4　(4)　2013/09

    DOI： 10.4172/2155-9619.1000162 　

  68. Evaluation of radiation-induced myocardial damage using iodine-123 beta-methyl-iodophenyl pentadecanoic acid scintigraphy Peer-reviewed

    Rei Umezawa, Kei Takase, Keiichi Jingu, Kentaro Takanami, Hideki Ota, Tomohiro Kaneta, Ken Takeda, Haruo Matsushita, Hisanori Ariga, Shoki Takahashi, Shogo Yamada

    JOURNAL OF RADIATION RESEARCH　54　(5)　880-889　2013/09

    DOI： 10.1093/jrr/rrt011 　

    ISSN： 0449-3060

  69. 呼吸性移動の影響を補正したSUV評価法に関する検討

    小笠原誠, 伊藤謙吾, 志田原美保, 土橋卓, 武田 賢, 角谷倫之, 藤田幸男, 南部武幸, 岸 和馬, 金田朋洋, 神宮啓一

    日本放射線技術学会東北部会雑誌　22　238-239　2013/01

  70. A brief review of Japanese guidelines for the clinical use of 18F-FDG-PET/MRI 2012 (Ver 1.0) Peer-reviewed

    Tomohiro Kaneta

    Annals of Nuclear Medicine　27　(4)　309-313　2013

    DOI： 10.1007/s12149-013-0710-z 　

    ISSN： 0914-7187 1864-6433

  71. A modified method of 3D-SSP analysis for amyloid PET imaging using [C-11]BF-227 Peer-reviewed

    Tomohiro Kaneta, Nobuyuki Okamura, Satoshi Minoshima, Katsutoshi Furukawa, Manabu Tashiro, Shozo Furumoto, Ren Iwata, Hiroshi Fukuda, Shoki Takahashi, Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai

    ANNALS OF NUCLEAR MEDICINE　25　(10)　732-739　2011/12

    DOI： 10.1007/s12149-011-0518-7 　

    ISSN： 0914-7187

  72. [Statistical voxel-based analysis of PET/SPECT images in dementia]. Peer-reviewed

    Kaneta T

    Nihon rinsho. Japanese journal of clinical medicine　69 Suppl 8　531-536　2011/10

    ISSN： 0047-1852

  73. Functional cortical deafferentation from the subcortical structures in a patient with early myoclonic encephalopathy: A functional neuroimaging study Peer-reviewed

    Mieko Hirose, Kazuhiro Haginoya, Hiroyuki Yokoyama, Soichiro Tanaka, Mitsugu Uematsu, Tomohiro Kaneta, Masaru Takayanagi, Kimiya Kon, Yasushi Yoshihara, Kazuie Iinuma, Shigeru Tsuchiya

    EPILEPSIA　51　(4)　699-702　2010/04

    DOI： 10.1111/j.1528-1167.2009.02399.x 　

    ISSN： 0013-9580

  74. FDG PET/CT Findings in Malignant Intraductal Papillary Mucinous Neoplasm of the Bile Ducts Peer-reviewed

    Kentaro Takanami, Tomomichi Hiraide, Tomohiro Kaneta, Hiroki Hayashi, Michiaki Unno, Fumiyoshi Fujishima, Hiroshi Fukuda, Shogo Yamada, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　35　(2)　83-85　2010/02

    DOI： 10.1097/RLU.0b013e3181c7bff0 　

    ISSN： 0363-9762

  75. F-18 FDG PET/CT Findings in Two Patients With Hepatic Angiomyolipoma With and Without Intratumoral Hemorrhage Peer-reviewed

    Kentaro Takanami, Tomohiro Kaneta, Shin Hitachi, Takayuki Yamada, Kazuyuki Ishida, Toshiki Rikiyama, Yu Katayose, Michiaki Unno, Shogo Yamada, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　35　(1)　18-21　2010/01

    DOI： 10.1097/RLU.0b013e3181c3611f 　

    ISSN： 0363-9762

  76. FDG-PETによる不明熱の診断 国内多施設共同研究

    窪田 和雄, 諸岡 都, 伊藤 公輝, 玉木 長良, 福田 寛, 金田 朋洋, 立石 宇貴秀, 中本 裕士, 村上 康二

    核医学　46　(3)　244-244　2009/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  77. Utility of subtraction ictal SPECT images in detecting focal leading activity and understanding the pathophysiology of spasms in patients with West syndrome Peer-reviewed

    Yosuke Kakisaka, Kazuhiro Haginoya, Mamiko Ishitobi, Noriko Togashia, Taro Kitamura, Keisuke Wakusawa, Ikuko Sato, Naomi Hino-Fukuyo, Mitsugu Uematsu, Mitsutoshi Munakata, Hiroyuki Yokoyama, Kazuie Iinuma, Tomohiro Kaneta, Shuichi Higano, Shigeru Tsuchiya

    EPILEPSY RESEARCH　83　(2-3)　177-183　2009/02

    DOI： 10.1016/j.eplepsyres.2008.11.005 　

    ISSN： 0920-1211

  78. Imaging of Hypoxic Tissues in Glioblastoma by PET with [18F]FRP-170, a New 18F-labeled 2-Nitroimidazole Analog.

    Shibahara I, Kumabe T, Kanamori M, Saito R, Sonoda Y, Watanabe M, Iwata R, Tashiro M, Takanami K, Kaneta T, Takai Y, Fukuda H, Tominaga T

    CYRIC Annual Report　139-145　2009

    More details Close

    CYRIC Annual Report 2009

  79. The difference between gross tumor volume and biological target volume in postoperative local recurrent rectal cancer; a preliminary study of PET/CT radiation therapy planning Peer-reviewed

    Keiichi Jingu, Ken, Takeda Takahiro, Metoki Yoshihiro Ogawa, Hisanori Ariga Shogo, Yamada Yoshihiro, Takai Yoshiyuki, Hosogai Tomohiro, Kaneda Masatoshi Mitsuya, Satoru Watanabe

    The official journal of the Japanese Society for Therapeutic Radiology and Oncology　20　(3)　127-131　2008/09/25

    DOI： 10.11182/jastro.20.127 　

    ISSN： 1040-9564

  80. Efficacy of superficial temporal artery-middle cerebral artery anastomosis with routine postoperative cerebral blood flow measurement during the acute stage in childhood moyamoya disease Peer-reviewed

    Miki Fujimura, Tomohiro Kaneta, Teiji Tominaga

    CHILDS NERVOUS SYSTEM　24　(7)　827-832　2008/07

    DOI： 10.1007/s00381-007-0551-y 　

    ISSN： 0256-7040

  81. [Assessment for the image interpretation of 111In-ibritumomab tiuxetan in the phase II study of 90Y-ibritumomab tiuxetan in patients with relapsed or refractory indolent B-cell lymphoma]. Peer-reviewed

    Oriuchi N, Koizumi K, Koizumi M, Terui S, Yamaura H, Imai Y, Kaneta T, Nawano S, Kubo A, Nishimura T, Kinuya S, Tobinai K, Endo K

    Kaku igaku. The Japanese journal of nuclear medicine　45　(2)　99-113　2008/05

    ISSN： 0022-7854

  82. 化学放射線療法を施行した食道癌のFDG-PET

    武田 賢, 小川 芳弘, 有賀 久哲, 坂谷内 徹, 藤本 圭介, 奈良崎 覚太朗, 神宮 啓一, 目時 隆博, 山田 章吾, 金田 朋洋, 高井 良尋, 仲田 栄子

    Radiation Medicine　26　(Suppl.I)　12-12　2008/04

    Publisher: (公社)日本医学放射線学会

    ISSN： 0288-2043

    eISSN： 1862-5274

  83. PET guided IMRTに関する初期研究

    神宮啓一, 金田朋洋, 武田 賢, 奈良崎覚太朗, 目時隆博, 小川芳弘, 有賀久哲, 藤本圭介, 高井良尋, 山田章吾

    日本医学放射線学会学術集会抄録集　258-258　2008/02

  84. PET/CT再構成処理条件におけるSUVの評価

    児玉 裕康, 木村 智圭, 酒見 紀久子, 小田桐 逸人, 南部 武幸, 阿部 養悦, 梁川 功, 鈴木 俊英, 金田 朋洋, 福田 寛

    日本放射線技術学会東北部会雑誌　(17)　134-135　2008/01

    Publisher: (公社)日本放射線技術学会-東北支部

  85. Temporal change in brain natriuretic peptide after radiotherapy for thoracic esophageal cancer Peer-reviewed

    Keiichi Jingu, Kenji Nemoto, Tomohiro Kaneta, Minako Oikawa, Yoshihiro Ogawa, Hisanori Ariga, Ken Takeda, Toru Sakayauchi, Keisuke Fujimoto, Kakutaro Narazaki, Yoshihiro Takai, Eiko Nakato, Hiroshi Fukuda, Shoki Takahashi, Shogo Yamada

    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS　69　(5)　1417-1423　2007/12

    ISSN： 0360-3016

  86. 術後再発食道癌における放射線化学療法前後のFDG-PET所見による予後予測

    神宮啓一, 金田朋洋, 根本建二, 小川芳弘, 有賀久哲, 高井良尋, 武田 賢, 高橋昭喜, 福田寛, 井上健太郎, 山田章吾

    核医学　44　(3)　290-290　2007/10

  87. Symptomatic hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in a child with moyamoya disease Peer-reviewed

    Miki Fujimura, Tomohiro Kaneta, Hiroaki Shimizu, Teiji Tominaga

    CHILDS NERVOUS SYSTEM　23　(10)　1195-1198　2007/10

    DOI： 10.1007/s00381-007-0361-2 　

    ISSN： 0256-7040

  88. 術後再発食道癌における放射線化学療法前後のFDG-PET所見による予後予測

    神宮啓一, 金田朋洋, 根本建二, 小川芳弘, 有賀久哲, 武田 賢, 小藤昌志, 坂谷内徹, 藤本 圭介, 福田寛, 山田章吾

    日本癌治療学会誌　42　(2)　583-583　2007/09

  89. Leigh脳症とその関連ミトコンドリア脳症のFDG-PETによる脳代謝異常の検討

    萩野谷 和裕, 植松 貢, 小林 朋子, 松本 葉子, 福與 なおみ, 北村 太郎, 冨樫 紀子, 山本 克哉, 高柳 勝, 宮林 重明, 金田 朋洋, 土屋 滋

    脳と発達　39　(Suppl.)　S257-S257　2007/06

    Publisher: (一社)日本小児神経学会

    ISSN： 0029-0831

    eISSN： 1884-7668

  90. パーキンソン病における視覚性注意障害

    鈴木 匡子, 澤田 陽一, 武田 篤, 平山 和美, 細貝 良行, 石岡 俊之, 西尾 慶之, 岡田 和枝, 長谷川 隆文, 金田 朋洋, 高橋 昭喜, 糸山 泰人, 森 悦朗

    臨床神経学　46　(12)　1074-1074　2006/12

    Publisher: (一社)日本神経学会

    ISSN： 0009-918X

    eISSN： 1882-0654

  91. パーキンソン病の高次視知覚障害

    平山 和美, 石岡 俊之, 武田 篤, 鈴木 匡子, 細貝 良行, 西尾 慶之, 岡田 和枝, 澤田 陽一, 長谷川 隆文, 金田 朋洋, 高橋 昭喜, 糸山 泰人, 森 悦朗

    臨床神経学　46　(12)　1074-1074　2006/12

    Publisher: (一社)日本神経学会

    ISSN： 0009-918X

    eISSN： 1882-0654

  92. Diffuse bone marrow uptake on F-18 FDG PET in patients with myelodysplastic syndromes Peer-reviewed

    Kentaro Inoue, Ken Okada, Hideo Harigae, Yasuyuki Taki, Ryoi Goto, Shigeo Kinomura, Shunsuke Kato, Tomohiro Kaneta, Hiroshi Fukuda

    CLINICAL NUCLEAR MEDICINE　31　(11)　721-723　2006/11

    DOI： 10.1097/01.rlu.0000242685.55001.67 　

    ISSN： 0363-9762

  93. Nitroglycerin treatment may enhance chemosensitivity to docetaxel and carboplatin in patients with lung adenocarcinoma Peer-reviewed

    Hiroyasu Yasuda, Katsutoshi Nakayama, Mika Watanabe, Satoshi Suzuki, Hiromi Fuji, Shoji Okinaga, Akio Kanda, Kiyoshi Zayasu, Takahiko Sasaki, Masanori Asada, Tomoko Suzuki, Motoki Yoshida, Shinsuke Yamanda, Daisuke Inoue, Tomohiro Kaneta, Takashi Kondo, Yoshihiro Takai, Hidetada Sasaki, Kazuhiro Yanagihara, Mutsuo Yamaya

    CLINICAL CANCER RESEARCH　12　(22)　6748-6757　2006/11

    DOI： 10.1158/1078-0432.CCR-06-1124 　

    ISSN： 1078-0432

  94. がんの機能イメージング 新低酸素細胞イメージング剤[18F]FRP-170の開発と臨床応用

    高井 良尋, 金田 朋洋, 袴塚 崇, 仲田 栄子, 岩田 錬, 船木 善仁, 石川 洋一, 辻谷 典彦

    日本放射線影響学会大会講演要旨集　49回　62-62　2006/09

    Publisher: (一社)日本放射線影響学会

    ISSN： 1347-8680

  95. Benefits of combining donepezil plus traditional Japanese herbal medicine on cognition and brain perfusion in Alzheimer's disease: A 12-week observerblind, donepezil monotherapy controlled trial Peer-reviewed

    M Maruyama, N Tomita, K Iwasaki, M Ootsuki, T Matsui, M Nemoto, N Okamura, M Higuchi, M Tsutsui, T Suzuki, T Seki, T Kaneta, K Furukawa, H Arai

    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY　54　(5)　869-871　2006/05

    DOI： 10.1111/j.1532-5415.2006.00722.x 　

    ISSN： 0002-8614

  96. Recurrent thymoma: Radiological (CT and FDG-PET) and histological (WHO criteria) features Peer-reviewed

    Hisao Ito, Kazuyoshi Shimada, Katsuhiko Isogami, Takashi Kondo, Tomohiro Kaneta, Shoki Takahashi, Hiroshi Fukuda

    Radiation Medicine - Medical Imaging and Radiation Oncology　24　(4)　292-296　2006/05

    DOI： 10.1007/s11604-005-1541-1 　

    ISSN： 0288-2043 1862-5274

  97. Atlantoaxial osteoarthritis in rheumatoid arthritis: FDG PET/CT findings Peer-reviewed

    T Kaneta, T Kakamatsuka, T Yamada, K Takase, A Sato, S Higano, H Ito, H Fukuda, S Takahashi, S Yamada

    CLINICAL NUCLEAR MEDICINE　31　(4)　209-209　2006/04

    DOI： 10.1097/01.rlu.0000204124.79497.bb 　

    ISSN： 0363-9762

  98. Database of normal human cerebral blood flow measured by SPECT: II. Quantification of I-123-IMP studies with ARG method and effects of partial volume correction Peer-reviewed

    K Inoue, H Ito, M Shidahara, R Goto, S Kinomura, K Sato, Y Taki, K Okada, T Kaneda, H Fukuda

    ANNALS OF NUCLEAR MEDICINE　20　(2)　139-146　2006/02

    DOI： 10.1007/BF02985626 　

    ISSN： 0914-7187

  99. Development of a novel hypoxia maker; [ 18F]FRP-170, and its initial clinical application for tumor imaging

    Yoshihiro Takai, E. Nakata, T. Kaneta, T. Hamatsuka, S. Yamada, R. Iwata, Y. Funaki, Y. Ishikawa, N. Tsujitani

    Japanese Journal of Clinical Radiology　51　(7)　837-843　2006

    ISSN： 0009-9252

  100. Impaired shifting of visual attention in Parkinson's disease Peer-reviewed

    Suzuki Kyoko, Sawada Yoichi, Takeda Atsushi, Hirayama Kazumi, Hosokai Yoshiyuki, Ishioka Toshiyuki, Okada Kazue, Nishio Yoshiyuki, Kaneta Tomohiro, Itoyama Yasuto, Takahashi Shoki, Mori Etsuro

    NEUROSCIENCE RESEARCH　55　S199　2006

    ISSN： 0168-0102

  101. Epileptic focus analysis in childhood epilepsy by using IMZ-SPECT Peer-reviewed

    Kitamura Taro, Kakisaka Yosuke, Haginoya Kazuhiro, Nakasato Nobukazu, Shamoto Hiroshi, Kaneta Tomohiro

    EPILEPSIA　47　85　2006

    ISSN： 0013-9580

  102. 耳鼻咽喉科疾患診断の最近の進歩頭頸部癌のPET診断

    福田 寛, 金田 朋洋, 窪田 和雄

    日本耳鼻咽喉科學會會報　108　(11)　1071-1076　2005/11/20

    Publisher: The Oto-Rhino-Laryngological Society of Japan, Inc.

    DOI： 10.3950/jibiinkoka.108.1071 　

    ISSN： 0030-6622

    More details Close

    18Fフルオロデオキシグルコース (FDG) を用いるPET (Posltron Emission Tomography) 検査により, 癌の糖代謝の程度, すなわちバイアビリテイーを反映する画像が得られる. このため形態情報を主とするCTやMRIと比べて以下の点で優れている. (1) 頸部リンパ節転移の原発巣の検出: PETによる検出率は平均30%でそれほど高くはないが, CT/MRIによる検出は困難である. (2) 病期診断 (特にリンパ節転移診断～: PETによる病期診断の感度, 特異度は平均84%, 89%である. 一方, 頭頸部は解剖学的構造が複雑であること, 組織密度差が少ないことからCT/MRIによる感度, 特異度は75%, 65%程度である. (3) 再発診断: 治療後の解剖学的構造の変化, 組織密度の変化のため, CT/MRIによる再発の診断精度は低く, 感度, 特異度はそれぞれ67%, 61%程度であった.<BR>一方, PETにも弱点がある. 1) 分解能が低いこと: PETの分解能は5～6mm程度であり, 1cm以下の腫瘍の検出率はかなり低下する. 2) 解剖学的情報の欠如: 糖代謝の多寡に依存した画像で解剖学的情報を欠く (最近, CTとPETを合体したCT/PETが導入され, この欠点が補なえるようになってきた). 3) 悪性腫瘍でも集積の少ないもの, 良性腫瘍や炎症などにも高集積を示す場合がある.<BR>PETは, 科学的データに基づく癌診療を行う上で, 極めて有用であるが, その限界についても十分把握した上で利用する必要がある.

  103. A case of high FDG-uptake into the myocardium after radiotherapy for esophageal cancer Peer-reviewed

    Keiichi Jingu, Kenji Nemoto, Tomohiro Kaneta, Yoshihiro Takai, Azusa Ichinose, Yoshihiro Ogawa, Shogo Yamada

    Nippon Acta Radiologica　65　(3)　266-269　2005/07/25

    ISSN： 0048-0428 1347-7951

  104. Effects of tissue heterogeneity on cerebral vascular response to acetazolamide stress measured by an I-123-IMP autoradiographic method with single-photon emission computed tomography Peer-reviewed

    H Ito, M Shidahara, K Inoue, R Goto, S Kinomura, Y Taki, K Okada, T Kaneta, K Sato, T Sato, H Fukuda

    ANNALS OF NUCLEAR MEDICINE　19　(4)　251-260　2005/06

    ISSN： 0914-7187

  105. Development of [ 18F]FRP-170 injection for imaging hypoxia by PET Peer-reviewed

    Yoichi Ishikawa, Yoshihito Funaki, Ren Iwata, Shozo Furumoto, Eiko Nakata, Yukitsuka Kudo, Tomohiro Kaneta, Takashi Hakamatsuka, Yoshihiro Takai, Shogo Yamada

    Kakuigaku　42　(1)　1-10　2005

    ISSN： 0022-7854

  106. [Performance evaluation of dual-head coincidence gamma camera for positron imaging]. Peer-reviewed

    Kaneta T, Yamaguchi K, Kurihara H, Abe Y, Yamazaki T, Hakamaduka T, Sakayauchi T, Takai Y, Maruoka S, Kinomura S, Fukuda H, Itoh M, Takahashi S, Yamada S

    Kaku igaku. The Japanese journal of nuclear medicine　39　(1)　47-53　2002/02

    ISSN： 0022-7854

  107. GSA肝シンチグラフィにおける肝摂取速度比曲線の有用性について

    阿部 養悦, 佐藤 和宏, 亀谷 一樹, 山崎 哲郎, 金田 朋洋, 袴塚 崇, 箕浦 衣里子, 山田 章吾, 丸岡 伸

    核医学　35　(9)　960-961　1998/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  108. 長期潜伏期間後に発症した放射線障害例の検討 Peer-reviewed

    武田 賢, 山田章吾, 高井良尋, 根本建二, 小川芳弘, 角藤芳久, 有賀久哲, 梅津篤司, 金田朋洋

    日本医学放射線学会雑誌　57　(7)　448-448　1997/06

Show all ︎Show first 5

Misc. 194

  1. PET and SPECT imaging of the brain: a review on the current status of nuclear medicine in Japan.

    Tomohiro Kaneta

    Japanese journal of radiology　38　(4)　343-357　2020/04/01

    Publisher: Springer

    DOI： 10.1007/s11604-019-00901-8 　

    ISSN： 1867-108X 1867-1071

  2. ソマトスタチン受容体シンチグラフィーが診断に有用であった膵内分泌腫瘍の1例

    繁永 大輔, 日野 彩子, 高野 祥子, 金田 朋洋, 吉田 啓介, 縄田 晋太郎, 井上 登美夫, 小林 規俊

    核医学　55　(1)　28-28　2018/12

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  3. NaF-PET標準化のためのファントム試験

    大崎 洋充, 尾川 松義, 西田 広之, 赤松 剛, 金田 朋洋, 千田 道雄, 立石 宇貴秀

    核医学　55　(Suppl.)　S212-S212　2018/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  4. 神経内分泌腫瘍のTheranostics ～Peptide Receptor Radionuclide Therapyの現状と今後の展望～

    高野 祥子, 小林 規俊, 金田 朋洋, 幡多 政治, 市川 靖史, 井上 登美夫

    臨床核医学　51　(3)　38-42　2018/05

    Publisher: 放射線診療研究会

    ISSN： 0912-5817

  5. ソマトスタチン受容体シンチグラフィーが診断に有用であった膵内分泌腫瘍の1例

    繁永大輔, 日野彩子, 高野祥子, 金田朋洋, 吉田啓介, 縄田晋太郎, 井上登美夫, 小林規俊

    核医学(Web)　55　(1)　2018

    ISSN： 2189-9932

  6. FDG PET/CTを用いた1st line分子標的治療終了後の予後予測の有用性の検討

    中井川 昇, 近藤 慶一, 金田 朋洋, 南村 和宏, 上野 大樹, 小林 一樹, 岸田 健, 池田 伊知郎, 蓮見 壽史, 槙山 和秀, 林 成彦, 逢坂 公人, 村岡 研太郎, 井上 登美夫, 矢尾 正祐

    日本癌治療学会学術集会抄録集　55回　O5-6　2017/10

    Publisher: (一社)日本癌治療学会

  7. FDG PET/CTを用いた1st line分子標的治療終了後の予後予測の有用性の検討

    中井川 昇, 近藤 慶一, 金田 朋洋, 南村 和宏, 上野 大樹, 小林 一樹, 岸田 健, 池田 伊知郎, 蓮見 壽史, 槙山 和秀, 林 成彦, 逢坂 公人, 村岡 研太郎, 井上 登美夫, 矢尾 正祐

    日本癌治療学会学術集会抄録集　55回　O5-6　2017/10

    Publisher: (一社)日本癌治療学会

  8. Feasibility of prognosis development for cancer of unknown primary (CUP) using F-18-FDG PET/CT to determine intratumoral heterogeneity and total lesion glycolysis (TLG)

    Yoshinobu Ishiwata, Tomohiro Kaneta, Keisuke Yoshida, Ayako Hino, Tomio Inoue

    JOURNAL OF NUCLEAR MEDICINE　58　2017/05

    ISSN： 0161-5505

    eISSN： 1535-5667

  9. Theranostics

    19　(4)　397-401　2017/04

    Publisher: 科学評論社

    ISSN： 1881-6568

  10. FDG PEET/CTを用いた1st line分子標的治療終了後の予後予測の有用性の検討

    中井川 昇, 近藤 慶一, 蓮見 壽史, 槙山 和秀, 林 成彦, 小林 一樹, 塩井 康一, 池田 伊知郎, 岸田 健, 金田 朋洋, 井上 登美夫, 上村 博司, 矢尾 正祐

    日本泌尿器科学会総会　105回　OP49-3　2017/04

    Publisher: (一社)日本泌尿器科学会総会事務局

  11. Evidence of peptide receptor radionuclide therapy for midgut neuroendocrine tumors and introduction in Japan

    19　(3)　285-290　2017/03

    Publisher: 科学評論社

    ISSN： 1881-6568

  12. 膵・消化管神経内分泌腫瘍の診断および治療の進歩 膵・消化管神経内分泌腫瘍に対する111In-ペンテトレオチドを用いた,ソマトスタチン受容体シンチグラフィー(SRS)の有用性

    小林規俊, 高野祥子, 金田朋洋, 市川靖史

    Mebio　34　(3)　2017

    ISSN： 0910-0474

  13. The future prospects of Celesteion, the latest PET/CT Scanner

    43　(3)　33-35　2016/03

    Publisher: エム・イー振興協会

    ISSN： 0910-7991

  14. もの忘れ外来患者におけるSPECT診断能の検討 大崎-田尻プロジェクト

    金田 朋洋, 中塚 晶博, 中村 馨, 関 隆志, 目黒 謙一, 山口 智, 壷井 匡浩

    Japanese Journal of Radiology　34　(Suppl.)　9-9　2016/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

  15. Multiple organ cancer : the diagnostic radiologist view

    70　(12)　1326-1330　2015/11

    Publisher: 医学書院

    ISSN： 0386-9857

  16. 長谷川式簡易知能スケールの再検討 ADにおける右頭頂葉血流との「逆相関」

    中塚 晶博, 金田 朋洋, 中村 馨, 関 隆志, 片山 宗一, 目黒 謙一

    Dementia Japan　29　(3)　383-383　2015/09

    Publisher: (一社)日本認知症学会

    ISSN： 1342-646X

  17. もの忘れ外来患者におけるSPECT診断能の検討 大崎-田尻プロジェクト

    金田 朋洋, 中塚 晶博, 中村 馨, 関 隆志, 山口 智, 壷井 匡浩, 目黒 謙一

    核医学　52　(1)　27-28　2015/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  18. Burn-associated delayed dilated cardiomyopathy evaluated by cardiac PET and SPECT: Report of a case.

    Reimu Fukui, Hideaki Suzuki, Noriko Miyagawa, Tomoyuki Endo, Tomohiro Kaneta, Koichiro Sugimura, Yasuharu Matsumoto, Shoki Takahashi, Yutaka Kagaya, Shigeki Kushimoto, Hiroaki Shimokawa

    Journal of cardiology cases　10　(5)　180-183　2014/11

    DOI： 10.1016/j.jccase.2014.07.005 　

  19. 地域在住高齢者における糖尿病と認知症の関係

    山口 智, 中塚 晶博, 中村 馨, 関 隆志, 金田 朋洋, 目黒 謙一

    Dementia Japan　28　(4)　480-480　2014/10

    Publisher: (一社)日本認知症学会

    ISSN： 1342-646X

  20. もの忘れ外来初診患者におけるSPECT診断能の検討 大崎-田尻プロジェクト

    金田 朋洋, 中塚 晶博, 中村 馨, 関 隆志, 山口 智, 壷井 匡浩, 目黒 謙一

    Dementia Japan　28　(4)　500-500　2014/10

    Publisher: (一社)日本認知症学会

    ISSN： 1342-646X

  21. Prognostic Probability of FDG-PET before Stereotactic Ablative Radiotherapy for Primary Lung Cancer –Review of the Literature.

    Jingu K, Yamamoto T, Kaneta T, Kadoya N, Takeda K, Matsushita H

    2014/07/01

  22. 心臓MRI検査を用いた放射線治療後の心筋変化の検出

    梅澤 玲, 高瀬 圭, 大田 英揮, 高浪 健太郎, 金田 朋洋, 神宮 啓一, 高橋 昭喜

    日独医報　59　(1)　114-114　2014/06

    Publisher: バイエル薬品(株)

    ISSN： 0912-0351

  23. 標準化PET/CTを用いた悪性腫瘍の薬効判定法の検討

    立石 宇貴秀, 鈴木 一史, 西田 広之, 大崎 洋充, 島田 直毅, 村野 剛志, 寺内 隆司, 巽 光朗, 金田 朋洋

    核医学　51　(1)　18-20　2014/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  24. 腫瘍性骨軟化症が疑われた症例におけるFDG PETの有用性

    荒井 晃, 常陸 真, 高浪 健太郎, 金田 朋洋, 高橋 昭喜

    核医学　51　(1)　23-23　2014/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  25. BF-227を用いたアミロイドPET早期像の有用性

    金田 朋洋, 荒井 晃, 高浪 健太郎, 高橋 昭喜, 岡村 信行, 古本 祥三, 谷内 一彦, 古川 勝敏, 荒井 啓行, 四月朔日 聖一, 田代 学, 岩田 練, 福田 寛, 工藤 幸司

    核医学　51　(1)　23-24　2014/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  26. 気管glomus腫瘍のFDG PET所見

    荒井 晃, 木下 知, 冨永 循哉, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 岡田 克典, 中村 保宏

    核医学　51　(1)　27-27　2014/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  27. パーキンソン病合併が疑われる特発性正常圧水頭症の臨床・画像的特徴についての研究

    馬場徹, 小田桐逸人, 岩崎真樹, 金田朋洋, 菅野重範, 飯塚統, 松田実, 森悦朗

    日本神経学会学術大会プログラム・抄録集　55th　(Suppl.)　560-S83　2014

    Publisher: (一社)日本神経学会

    ISSN： 0009-918X

    eISSN： 1882-0654

  28. FDG-PETで集積が見られた胸椎骨棘近傍線維化の2症例

    負門 克典, 冨永 循哉, 高浪 健太郎, 金田 朋洋, 高瀬 圭, 高橋 昭喜

    肺癌　53　(5)　506-506　2013/10

    Publisher: (NPO)日本肺癌学会

    ISSN： 0386-9628

    eISSN： 1348-9992

  29. FDG PET/CTを用いた脂肪を含有する副腎腫瘍のホルモン分泌能評価

    高浪 健太郎, 荒井 晃, 金田 朋洋, 高橋 昭喜

    核医学　50　(3)　S233-S233　2013/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  30. 経口BMIPPとSPECT/CTを用いた3次元胸管シンチグラフィーによる胸管描出と正常変異の評価

    高浪 健太郎, 荒井 晃, 金田 朋洋, 高橋 昭喜

    核医学　50　(3)　S245-S245　2013/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  31. 気管Glomus腫瘍の1例

    木下 知, 冨永 循哉, 負門 克典, 大田 英揮, 松浦 智徳, 金田 朋洋, 高瀬 圭, 高橋 昭喜, 中村 保宏, 遠藤 千顕

    日本医学放射線学会秋季臨床大会抄録集　49回　S598-S598　2013/09

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  32. 腎腫瘍症例

    木下 知, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 福田 寛

    みちのく核医学の会　20　(1)　35-37　2013/05

    Publisher: みちのく核医学の会

    ISSN： 0917-5741

  33. 赤色髄の核医学・MRI所見

    高木 英誠, 常陸 真, 金田 朋洋, 高橋 昭喜

    核医学　50　(2)　73-73　2013/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  34. 多系統萎縮症における脳血流SPECT所見

    荒井 晃, 松村 美樹子, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 岡田 賢, 井上 健太郎, 後藤 了以, 福田 寛

    Japanese Journal of Radiology　31　(Suppl.I)　1-1　2013/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

    eISSN： 1867-108X

  35. 3D-SSP変法を用いたBF-227アミロイドPET解析

    金田 朋洋, 松村 美樹子, 青木 英和, 荒井 晃, 高浪 健太郎, 高橋 昭喜, 岡村 信行, 谷内 一彦, 古川 勝敏, 荒井 啓行, 四月朔日 聖一, 田代 学, 岩田 練, 福田 寛, 工藤 幸司, 蓑島 聡

    Japanese Journal of Radiology　31　(Suppl.I)　1-1　2013/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

  36. 稀な転移様式を呈した食道癌の1例

    荒井 晃, 佐谷 望, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 福田 寛

    Japanese Journal of Radiology　31　(Suppl.I)　9-9　2013/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

    eISSN： 1867-108X

  37. 【PET/CT・核医学 最新情報】 比較的まれな膵腫瘍のFDG-PET/CT所見

    高浪 健太郎, 金田 朋洋, 福田 寛, 高橋 昭喜

    臨床放射線　57　(12)　1654-1662　2012/11

    Publisher: 金原出版(株)

    ISSN： 0009-9252

  38. [11C]BF-227を用いたAmyloid PETにおける統計学的画像解析 3D-SSP法とeZIS法との比較

    荒井 晃, 金田 朋洋, 高浪 健太郎, 高橋 昭喜, 岡村 信行, 谷内 一彦, 田代 学, 岩田 錬, 神田 寛, 工藤 幸司, 荒井 啓行

    核医学　49　(4)　416-417　2012/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  39. FDG PET/CTで偽陽性または偽陰性を呈した副腎結節の症例

    高浪 健太郎, 荒井 晃, 金田 朋洋, 高橋 昭喜, 福田 寛

    核医学　49　(4)　418-418　2012/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  40. 心筋脂肪酸シンチグラフィーによる照射野に含まれた心筋代謝変化に関する検討

    梅澤玲, 高瀬圭, 高浪健太郎, 大田英揮, 神宮啓一, 金田朋洋, 高橋昭喜

    日独医報　57　(1)　105-105　2012/08/03

    Publisher: バイエル薬品(株)

    ISSN： 0912-0351

  41. 心臓腫瘍/偽腫瘍の絶食下F-18 FDG PET/CT所見

    高浪 健太郎, 荒井 晃, 金田 朋洋, 福田 寛, 高橋 昭喜

    日本医学放射線学会秋季臨床大会抄録集　48回　S548-S548　2012/08

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  42. 肝細胞癌・通常型胆管癌以外の肝胆道系腫瘍のF-18FDG PET/CT所見

    高浪 健太郎, 金田 朋洋, 福田 寛, 高橋 昭喜

    核医学　49　(3)　S211-S211　2012/08

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  43. Voxel-based analyses of amyloid PET using BF-227. Differences in results of 3D-SSP and SPM-based methods

    Akira Arai, Tomohiro Kaneta, Nobuyuki Okamura, Manabu Tashiro, Ren Iwata, Hiroshi Fukuda, Shoki Takahashi, Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai

    JOURNAL OF NUCLEAR MEDICINE　53　2012/05

    ISSN： 0161-5505

    eISSN： 1535-5667

  44. 多系統萎縮症における脳血流SPECT所見

    荒井 晃, 松村 美樹子, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 岡田 賢, 井上 健太郎, 後藤 了以, 福田 寛

    核医学　49　(1)　28-28　2012/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  45. 3D-SSP変法を用いたBF-227アミロイドPET解析

    金田 朋洋, 松村 美樹子, 青木 英和, 荒井 晃, 高浪 健太郎, 高橋 昭喜, 岡村 信行, 谷内 一彦, 古川 勝敏, 荒井 啓行, 四月朔日 聖一, 田代 学, 岩田 練, 福田 寛, 工藤 幸司, 蓑島 聡

    核医学　49　(1)　29-29　2012/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  46. Cerebral proliferative angiopathyが疑われた一例

    青木 英和, 麦倉 俊司, 金田 朋洋, 佐谷 望, 荒井 晃, 高浪 健太郎, 高橋 昭喜

    核医学　49　(1)　32-33　2012/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  47. 稀な転移様式を呈した食道癌の1例

    荒井 晃, 佐谷 望, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 福田 寛

    核医学　49　(1)　33-33　2012/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  48. 食道癌症例における原発巣のFDG集積と基礎代謝の相関

    三田村 篤, 平出 智道, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 福田 寛

    Japanese Journal of Radiology　30　(Suppl.I)　7-7　2012/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

    eISSN： 1867-108X

  49. 比較的大きなclear cell type renal cell carcinomaの核異型度とFDG集積の相関

    高浪 健太郎, 平出 智道, 金田 朋洋, 山田 章吾, 高橋 昭喜, 三田村 篤, 岡田 賢, 後藤 了以, 福田 寛

    Japanese Journal of Radiology　30　(Suppl.I)　7-7　2012/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

    eISSN： 1867-108X

  50. 比較的稀な肝胆道系腫瘍のFDG PET/CT所見

    高浪 健太郎, 平出 智道, 金田 朋洋, 山田 章吾, 高橋 昭喜, 岡田 賢, 後藤 了以, 福田 寛

    Japanese Journal of Radiology　30　(Suppl.I)　15-15　2012/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

    eISSN： 1867-108X

  51. 比較的稀な肝胆道系腫瘍のF-18 FDG PET/CT所見

    高浪 健太郎, 荒井 晃, 金田 朋洋, 福田 寛, 高橋 昭喜

    日本医学放射線学会学術集会抄録集　71回　S146-S146　2012/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  52. A modified method of 3D-SSP analysis for amyloid PET imaging using [C-11]BF-227

    Tomohiro Kaneta, Nobuyuki Okamura, Satoshi Minoshima, Katsutoshi Furukawa, Manabu Tashiro, Shozo Furumoto, Ren Iwata, Hiroshi Fukuda, Shoki Takahashi, Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai

    ANNALS OF NUCLEAR MEDICINE　25　(10)　732-739　2011/12

    DOI： 10.1007/s12149-011-0518-7 　

    ISSN： 0914-7187

  53. 食道癌症例における原発巣のFDG集積と基礎代謝の相関

    三田村 篤, 平出 智道, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 福田 寛

    核医学　48　(4)　435-435　2011/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  54. 比較的大きなclear cell type renal cell carcinomaの核異型度とFDG集積の相関

    高浪 健太郎, 平出 智道, 金田 朋洋, 山田 章吾, 高橋 昭喜, 三田村 篤, 岡田 賢, 後藤 了以, 福田 寛

    核医学　48　(4)　435-435　2011/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  55. 比較的稀な肝胆道系腫瘍のFDG PET/CT所見

    高浪 健太郎, 平出 智道, 金田 朋洋, 山田 章吾, 高橋 昭喜, 岡田 賢, 後藤 了以, 福田 寛

    核医学　48　(4)　440-440　2011/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  56. Prediction of nuclear grade of clear-cell-type renal cell carcinoma 4cm or larger using F-18 FDG PET/CT: A preliminary study

    K. Takanami, Y. Nakamura, T. Kaneta, H. Fukuda, S. Takahashi

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　38　S362-S363　2011/10

    ISSN： 1619-7070

  57. Additional value of FDG PET/CT to contrast-enhanced CT in the detection of malignant intraductal papillary mucinous neoplasms of the pancreas with mural nodules

    K. Takanami, T. Kaneta, H. Fukuda, S. Takahashi

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　38　S373-S374　2011/10

    ISSN： 1619-7070

  58. 3D-SSP変法によるBF-227を用いたアミロイドPET解析

    金田 朋洋, 岡村 信行, 蓑島 聡, 古川 勝敏, 四月朔日 聖一, 田代 学, 岩田 錬, 福田 寛, 谷内 一彦, 工藤 幸司, 荒井 啓行

    核医学　48　(3)　S287-S287　2011/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  59. 比較的稀な膵腫瘍のF-18 FDG PET/CT所見

    高浪 健太郎, 金田 朋洋, 福田 寛, 高橋 昭喜

    日本医学放射線学会秋季臨床大会抄録集　47回　S535-S535　2011/09

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  60. Additional value of FDG PET/CT to contrast-enhanced CT in the differentiation between benign and malignant intraductal papillary mucinous neoplasms of the pancreas with mural nodules

    Kentaro Takanami, Tomomichi Hiraide, Masashi Tsuda, Yasuhiro Nakamura, Tomohiro Kaneta, Kei Takase, Hiroshi Fukuda, Shoki Takahashi

    ANNALS OF NUCLEAR MEDICINE　25　(7)　501-510　2011/08

    DOI： 10.1007/s12149-011-0494-y 　

    ISSN： 0914-7187

    eISSN： 1864-6433

  61. Positive correlations between tumor uptake on FDG PET and energy expenditure of patients with esophageal cancer

    Atsushi Mitamura, Tomohiro Kaneta, Go Miyata, Kentaro Takanami, Tomomichi Hiraide, Hiroshi Fukuda, Shoki Takahashi, Susumu Satomi

    ANNALS OF NUCLEAR MEDICINE　25　(4)　241-246　2011/05

    DOI： 10.1007/s12149-010-0456-9 　

    ISSN： 0914-7187

    eISSN： 1864-6433

  62. F-18 FDG・I-123 BMIPP・心臓MRIで放射線心筋障害が疑われた3症例

    梅澤 玲, 高瀬 圭, 高浪 健太郎, 神宮 啓一, 有賀 久哲, 金田 朋洋, 大田 英揮, 高橋 昭喜, 山田 章吾

    日本医学放射線学会学術集会抄録集　70回　S209-S209　2011/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  63. Unique discrepancy between cerebral blood flow and glucose metabolism in hemimegalencephaly

    Mitsugu Uematsu, Kazuhiro Haginoya, Noriko Togashi, Naomi Hino-Fukuyo, Tojo Nakayama, Atsuo Kikuchi, Yu Abe, Keisuke Wakusawa, Yoko Matsumoto, Yosuke Kakisaka, Tomoko Kobayashi, Mieko Hirose, Hiroyuki Yokoyama, Kazuie Iinuma, Masaki Iwasaki, Nobukazu Nakasato, Tomohiro Kaneta, Manami Akasaka, Atsushi Kamei, Shigeru Tsuchiya

    EPILEPSY RESEARCH　92　(2-3)　201-208　2010/12

    DOI： 10.1016/j.eplepsyres.2010.09.010 　

    ISSN： 0920-1211

    eISSN： 1872-6844

  64. SPECT/CTを用いたI-123 BMIPP経口投与による胸管シンチグラフィの初期経験

    高浪 健太郎, 平出 智道, 金田 朋洋, 福田 寛, 高橋 昭喜

    核医学　47　(3)　424-424　2010/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  65. 頭蓋内出血を伴ったPRES(posterior renersible encephalopathy syndrome)の2例

    高澤 千晶, 日向野 修一, 麦倉 俊司, 梅津 篤司, 村田 隆起, 加藤 裕美子, 金田 朋洋, 高橋 昭喜

    Japanese Journal of Radiology　28　(Suppl.I)　1-1　2010/07

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

  66. 食道癌症例における癌腫による基礎代謝の亢進の程度と術前FDG-PET画像による集積の関連性の検討

    三田村 篤, 宮田 剛, 里見 進, 平出 智道, 高浪 健太郎, 金田 朋洋, 高橋 昭喜, 福田 寛

    核医学　47　(2)　186-186　2010/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  67. F-18-fluorodeoxyglucose positron emission tomography immediately after chemoradiotherapy predicts prognosis in patients with locoregional postoperative recurrent esophageal cancer

    Keiichi Jingu, Tomohiro Kaneta, Kenji Nemoto, Ken Takeda, Yoshihiro Ogawa, Hisanori Ariga, Masashi Koto, Toru Sakayauchi, Yoshihiro Takai, Shoki Takahashi, Shogo Yamada

    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY　15　(2)　184-190　2010/04

    DOI： 10.1007/s10147-010-0044-y 　

    ISSN： 1341-9625

  68. Focal dose escalation using FDG-PET-guided intensity-modulated radiation therapy boost for postoperative local recurrent rectal cancer: a planning study with comparison of DVH and NTCP

    Keiichi Jingu, Hisanori Ariga, Tomohiro Kaneta, Yoshihiro Takai, Ken Takeda, Lindel Katja, Kakutaro Narazaki, Takahiro Metoki, Keisuke Fujimoto, Rei Umezawa, Yoshihiro Ogawa, Kenji Nemoto, Masashi Koto, Masatoshi Mitsuya, Naruhiro Matsufuji, Shoki Takahashi, Shogo Yamada

    BMC CANCER　10　127　2010/04

    DOI： 10.1186/1471-2407-10-127 　

    ISSN： 1471-2407

  69. Clinical impact of whole body FDG-PET for recurrent biliary cancer: a multicenter study

    Kazuhiro Kitajima, Koji Murakami, Kakuko Kanegae, Nagara Tamaki, Tomohiro Kaneta, Hiroshi Fukuda, Kotaro Nakajima, Hirofumi Fujii, Ukihide Tateishi, Kazuo Kubota, Tsuyoshi Suga, Yuji Nakamoto

    ANNALS OF NUCLEAR MEDICINE　23　(8)　709-715　2009/10

    DOI： 10.1007/s12149-009-0297-6 　

    ISSN： 0914-7187

  70. Clinical significance of performing F-18-FDG PET on patients with gastrointestinal stromal tumors: a summary of a Japanese multicenter study

    Tomohiro Kaneta, Shoki Takahashi, Hiroshi Fukuda, Yukiko Arisaka, Noboru Oriuchi, Takayuki Hayashi, Hirofumi Fujii, Takashi Terauchi, Ukihide Tateishi, Kazuo Kubota, Tadashi Hara, Yuji Nakamoto, Kazuhiro Kitajima, Koji Murakami

    ANNALS OF NUCLEAR MEDICINE　23　(5)　459-464　2009/07

    DOI： 10.1007/s12149-009-0257-1 　

    ISSN： 0914-7187

  71. F-18 FDG PET/CT Scan in Biliary Cystadenocarcinoma

    Kentaro Takanami, Tomohiro Kaneta, Shogo Yamada, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　34　(7)　470-472　2009/07

    DOI： 10.1097/RLU.0b013e3181a7d16b 　

    ISSN： 0363-9762

  72. F-18 FDG PET/CT Findings of Primary Carcinoma of the Fallopian Tube

    Kentaro Takanami, Tomohiro Kaneta, Shogo Yamada, Hiroshi Fukuda, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　34　(6)　377-378　2009/06

    DOI： 10.1097/RLU.0b013e3181a345db 　

    ISSN： 0363-9762

  73. FDG Accumulation in Obturator Herniation of the Bladder Mimicking Metastatic Disease

    Tomohiro Kaneta, Kentaro Takanami, Atsushi Mitamura, Tomomichi Hiraide, Hiroshi Fukuda, Shogo Yamada, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　34　(6)　395-397　2009/06

    DOI： 10.1097/RLU.0b013e3181a3457c 　

    ISSN： 0363-9762

  74. The Leptomeningeal "Ivy Sign" on Fluid-Attenuated Inversion Recovery MR Imaging in Moyamoya Disease: A Sign of Decreased Cerebral Vascular Reserve?

    N. Mori, S. Mugikura, S. Higano, T. Kaneta, M. Fujimura, A. Umetsu, T. Murata, S. Takahashi

    AMERICAN JOURNAL OF NEURORADIOLOGY　30　(5)　930-935　2009/05

    DOI： 10.3174/ajnr.A1504 　

    ISSN： 0195-6108

  75. Clinical Value of Whole-body FDG-PET for Recurrent Gastric Cancer: A Multicenter Study

    Yuji Nakamoto, Kaori Togashi, Tomohiro Kaneta, Hiroshi Fukuda, Kotaro Nakajima, Kazuhiro Kitajima, Koji Murakami, Hirofumi Fujii, Mitsuo Satake, Ukihide Tateishi, Kazuo Kubota, Michio Senda

    JAPANESE JOURNAL OF CLINICAL ONCOLOGY　39　(5)　297-302　2009/05

    DOI： 10.1093/jjco/hyp010 　

    ISSN： 0368-2811

  76. 肺結節検出用CADシステムの診断性能比較 放射線科医vs.Lung VCAR vs.Lung CARE

    川住 祐介, 山田 隆之, 高瀬 圭, 松橋 俊夫, 津田 雅視, 清治 和将, 奥本 忠之, 金田 朋洋, 高橋 昭喜

    Japanese Journal of Radiology　27　(Suppl.)　1-1　2009/04

    Publisher: (公社)日本医学放射線学会

    ISSN： 1867-1071

  77. Incidence and risk factors for symptomatic cerebral hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in patients with moyamoya disease

    Miki Fujimura, Shun Mugikura, Tomohiro Kaneta, Hiroaki Shimizu, Teiji Tominaga

    SURGICAL NEUROLOGY　71　(4)　442-447　2009/04

    DOI： 10.1016/j.surneu.2008.02.031 　

    ISSN： 0090-3019

  78. Cerebral ischemia owing to compression of the brain by swollen temporal muscle used for encephalo-myo-synangiosis in moyamoya disease

    Miki Fujimura, Tomohiro Kaneta, Hiroaki Shimizu, Teiji Tominaga

    NEUROSURGICAL REVIEW　32　(2)　245-249　2009/04

    DOI： 10.1007/s10143-009-0184-6 　

    ISSN： 0344-5607

  79. 胆道癌の再発診断におけるFDG-PETの臨床的有用性の検討【多施設共同研究】

    北島 一宏, 村上 康二, 鐘ヶ江 香久子, 金田 朋洋, 中島 光太郎, 藤井 博史, 立石 宇貴秀, 窪田 和雄, 中本 裕士, 菅 剛

    日本医学放射線学会学術集会抄録集　68回　S204-S204　2009/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  80. 骨軟部腫瘍診断におけるFDG PET検査の有用性の検討

    藤井 博史, 山口 雅之, 立石 宇貴秀, 寺内 隆, 金田 朋洋, 中本 裕士, 鐘ヶ江 香久子, 織内 昇, 中島 光太郎, 窪田 和雄

    日本医学放射線学会学術集会抄録集　68回　S206-S206　2009/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  81. Comparative study of FDG PET/CT and conventional imaging in the staging of rhabdomyosarcoma

    Ukihide Tateishi, Ako Hosono, Atsushi Makimoto, Yuki Nakamoto, Tomohiro Kaneta, Hiroshi Fukuda, Koji Murakami, Takashi Terauchi, Tsuyoshi Suga, Tomio Inoue, Edmund E. Kim

    ANNALS OF NUCLEAR MEDICINE　23　(2)　155-161　2009/02

    DOI： 10.1007/s12149-008-0219-z 　

    ISSN： 0914-7187

  82. FDG-PETを施行したsolitary fibrous tumor(SFT)の2例

    吉田 さやか, 金田 朋洋, 高浪 健太郎, 高橋 昭喜, 三田村 篤, 丸岡 伸, 福田 寛

    核医学　45　(4)　375-375　2008/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  83. もやもや病術後過灌流評価における3D-SSPの有用性について

    金田 朋洋, 高浪 健太郎, 吉田 さやか, 阿部 恵子, 高橋 昭喜, 藤村 幹, 三田村 篤, 細貝 良行, 丸岡 伸, 福田 寛

    核医学　45　(4)　377-377　2008/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  84. Association of (18)FDG Uptake by Bone Marrow and Spleen with Hematological Parameters in Patients with and without Malignancy

    K. Inoue, K. Okada, R. Goto, Y. Taki, S. Kinomura, T. Kaneta, H. Fukuda

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　35　S260-S260　2008/10

    ISSN： 1619-7070

  85. Q fever with lymphadenopathy on F-18FDG PET

    Kentaro Takanami, Tomohiro Kaneta, Tsutomu Tamada, Takavuki Yamada, Shuichi Higano, Shogo Yamada, Hiroshi Fukuda, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　33　(6)　436-437　2008/06

    DOI： 10.1097/RLU.0b013e318170d52e 　

    ISSN： 0363-9762

  86. 消化管間葉系腫瘍(GIST)におけるFDG PETの有用性について 東北大学病院症例の解析

    金田 朋洋, 高浪 健太郎, 平出 智道, 高澤 千晶, 三田村 篤, 高橋 昭喜, 福田 寛

    核医学　45　(2)　140-140　2008/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  87. Validation of the use of calibration factors between the iodine concentration and the computed tomography number measured outside the objects for estimation of iodine concentration inside the objects: phantom experiment

    Kentaro Takanami, Shuichi Higano, Kei Takase, Tomohiro Kaneta, Takayuki Yamada, Hiroki Ishiya, Issei Mori, Shoki Takahashi

    RADIATION MEDICINE　26　(4)　237-243　2008/05

    DOI： 10.1007/s11604-007-0220-9 　

    ISSN： 1862-5274

  88. 16列MDCTによる食道癌リンパ節転移の評価

    森田 佳明, 高瀬 圭, 山田 隆之, 佐藤 明弘, 松橋 俊夫, 金田 朋洋, 日向野 修一, 高橋 昭喜, 市川 宏文

    Radiation Medicine　26　(Suppl.I)　2-2　2008/04

    Publisher: (公社)日本医学放射線学会

    ISSN： 0288-2043

  89. 経腸IMP投与全身像による門脈体循環シャント評価

    松本 世津, 高浪 健太郎, 金田 朋洋, 丸岡 伸, 高橋 昭喜, 山田 章吾, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    Radiation Medicine　26　(Suppl.I)　13-13　2008/04

    Publisher: (公社)日本医学放射線学会

    ISSN： 0288-2043

    eISSN： 1862-5274

  90. FDG PET for esophageal cancer complicated by sarcoidosis mimicking mediastinal and hilar lymph node metastases - Two case reports

    Kentaro Takanami, Tomohiro Kaneta, Takayuki Yamada, Shigeo Kinomura, Shogo Yamada, Hiroshi Fukuda, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　33　(4)　258-261　2008/04

    DOI： 10.1097/RLU.0b013e3181662fda 　

    ISSN： 0363-9762

  91. dual energy CTによる副腎結節病変の単純CT値の検討

    山田 隆之, 高瀬 圭, 松橋 俊夫, 津田 雅視, 清治 和将, 奥本 忠之, 金田 朋洋, 高橋 昭喜

    日本医学放射線学会学術集会抄録集　67回　S214-S214　2008/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

  92. 食道癌術後に縦隔リンパ節がFDG PETで偽陽性を呈した一例

    三田村 篤, 平出 智道, 高浪 健太郎, 金田 朋洋, 丸岡 伸, 山田 章吾, 高橋 昭喜, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    核医学　45　(1)　48-48　2008/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  93. Phosphaturic mesenchymal tumorの一例

    平出 智道, 高浪 健太郎, 金田 朋洋, 丸岡 伸, 山田 章吾, 高橋 昭喜, 三田村 篤, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    核医学　45　(1)　50-50　2008/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  94. FDG PETで高集積を呈した非腫瘍性卵巣病変の一例

    高浪 健太郎, 平出 智道, 金田 朋洋, 丸岡 伸, 山田 章吾, 高橋 昭喜, 三田村 篤, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    核医学　45　(1)　50-50　2008/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  95. PET/CTでの吸収補正アーチファクトにおける高吸収体の「動き」の影響

    金田 朋洋, 高浪 健太郎, 平出 智道, 丸岡 伸, 山田 章吾, 高橋 昭喜, 三田村 篤, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    核医学　45　(1)　50-51　2008/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  96. もやもや病の解析ソフトによる脳血流量の検討

    酒見 紀久子, 小田桐 逸人, 児玉 裕康, 木村 智圭, 舛山 葉菜子, 南部 武幸, 阿部 養悦, 梁川 功, 福田 寛, 金田 朋洋, 佐藤 多智雄

    日本放射線技術学会東北部会雑誌　(17)　130-131　2008/01

    Publisher: (公社)日本放射線技術学会-東北支部

  97. Validation of the use of calibration factors between the iodine concentration and the computed tomography number measured outside the objects for estimation of iodine concentration inside the objects: phantom experiment.

    TAKANAMI Kentaro, HIGANO Shuichi, TAKASE Kei, KANETA Tomohiro, YAMADA Takayuki, ISHIYA Hiroki, MORI Issei, TAKAHASHI Shoki

    Radiat Med　26　(4)　237-243　2008

    DOI： 10.1007/s11604-007-0220-9 　

    ISSN： 0288-2043

  98. Increase of serum CA19-9 level without an evident lesion on conventional Imaging is insufficient for justification of (18)FDG-PET examination

    Kentaro Inoue, Ken Okada, Yasuyuki Taki, Ryoi Goto, Shigeo Kinomura, Tomohiro Kaneta, Hiroshi Fukuda

    HEPATO-GASTROENTEROLOGY　55　(81)　46-49　2008/01

    ISSN： 0172-6390

  99. Evaluation of portosystemic shunt caused by patent ductus venosus through sequential whole-body scanning using per-sigmoid colon I-123-IMP scintigraphy

    Tomohiro Kaneta, Motoshi Wada, Kentaro Takanami, Tomohiro Ishii, Setsu Matsumoto, Ken Okada, Hiroshi Fukuda, Shogo Yamada, Shoki Takahashi

    ANNALS OF NUCLEAR MEDICINE　21　(10)　597-601　2007/12

    DOI： 10.1007/s12149-007-0072-5 　

    ISSN： 0914-7187

  100. 経腸IMP投与全身像による門脈体循環シャント評価

    松本 世津, 高浪 健太郎, 金田 朋洋, 丸岡 伸, 高橋 昭喜, 山田 章吾, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    核医学　44　(4)　388-388　2007/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  101. 間質性肺炎症例における生理的心筋集積の検討

    高浪 健太郎, 松本 世津, 金田 朋洋, 丸岡 伸, 日向野 修一, 高橋 昭喜, 山田 章吾, 福田 寛

    核医学　44　(4)　392-392　2007/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  102. PET/CTでの吸収補正アーチファクトにおける高吸収体の「動き」の影響

    金田 朋洋, 高浪 健太郎, 丸岡 伸, 木之村 重男, 福田 寛, 山田 章吾, 高橋 昭喜

    核医学　44　(3)　286-286　2007/10

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  103. Intense FDG uptake in the ovary with painless torsion

    Kentaro Takanami, Tomohiro Kaneta, Hitoshi Niikura, Shigeo Kinomura, Shogo Yamada, Hiroshi Fukuda, Shoki Takahashi

    CLINICAL NUCLEAR MEDICINE　32　(10)　805-806　2007/10

    DOI： 10.1097/RLU.0b013e318148b4a7 　

    ISSN： 0363-9762

  104. Diagnosing active inflammation in the SAPHO syndrome using (18)FDG-PET/CT in suspected metastatic vertebral bone tumors

    Kentaro Inoue, Tatsuo Yamaguchi, Hiroshi Ozawa, Ken Okada, Yasuyuki Taki, Ryoi Goto, Shigeo Kinomura, Tomohiro Kaneta, Hiroshi Fukuda

    ANNALS OF NUCLEAR MEDICINE　21　(8)　477-480　2007/10

    DOI： 10.1007/s12149-007-0051-x 　

    ISSN： 0914-7187

  105. Tumor hypoxia imaging with [F-18] fluoronitroimidazole in non-small-cell lung cancer

    Hiroyasu Yasuda, Tomohiro Kaneta, Yoshihiro Takai, Katsutoshi Nakayama, Ren Iwata, Masatoshi Ito, Michihiko Tsujitani, Shoki Takahashi, Shogo Yamada, Takahiko Sasaki

    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY　55　(7)　1142-1144　2007/07

    DOI： 10.1111/j.1532-5415.2007.01218.x 　

    ISSN： 0002-8614

  106. High-density materials do not always induce artifacts on PET/CT: What is responsible for the difference?

    Tomohiro Kaneta, Kentaro Takanami, Yuji Wakayama, Akihiro Sato, Shuichi Higano, Hiroshi Fukuda, Shogo Yamada, Shoki Takahashi

    NUCLEAR MEDICINE COMMUNICATIONS　28　(6)　495-499　2007/06

    DOI： 10.1097/MNM.0b013e3281744468 　

    ISSN： 0143-3636

    eISSN： 1473-5628

  107. Bronchial atresiaのCT診断

    佐藤 幸子, 山田 隆之, 高瀬 圭, 佐藤 明弘, 金田 朋洋, 常陸 真, 石橋 忠司, 高橋 昭喜

    Radiation Medicine　25　(Suppl.I)　23-23　2007/04

    Publisher: (公社)日本医学放射線学会

    ISSN： 0288-2043

  108. OE-345 Determinants of Left Ventricular Reverse Remodeling after Cardiac Resynchronization Therapy : Evaluation Using Quantitative Gated Myocardial Perfusion SPECT(Heart failure, clinical-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

    Wakayama Yuji, Kumagai Koji, Fukuda Koji, Sugai Yoshinao, Hirose Masanori, Oikawa Minako, Sugimura Koichiro, Kagaya Yutaka, Kaneta Tomohiro, Fukuda Hiroshi, Shimokawa Hiroaki

    Circulation journal : official journal of the Japanese Circulation Society　71　237-237　2007/03/01

    Publisher: Japanese Circulation Society

    ISSN： 1346-9843

  109. OE-348 Reverse Remodeling after Cardiac Resynchronization Therapy Influences Cardiac Events due to Heart Failure but not Ventricular Arrhythmias(Heart failure, clinical-03, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

    Wakayama Yuji, Kumagai Koji, Fukuda Koji, Sugai Yoshinao, Hirose Masanori, Oikawa Minako, Sugimura Koichiro, Kagaya Yutaka, Kaneta Tomohiro, Fukuda Hiroshi, Shimokawa Hiroaki

    Circulation journal : official journal of the Japanese Circulation Society　71　238-238　2007/03/01

    Publisher: Japanese Circulation Society

    ISSN： 1346-9843

  110. Temporary neurologic deterioration due to cerebral hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in patients with adult-onset moyamoya disease

    Miki Fujimura, Tomohiro Kaneta, Shunji Mugikura, Hiroaki Shimizu, Teiji Tominaga

    SURGICAL NEUROLOGY　67　(3)　273-282　2007/03

    DOI： 10.1016/j.surneu.2006.07.017 　

    ISSN： 0090-3019

  111. 乳頭状腎細胞癌の病理学的サブタイプとCT画像との比較

    山田 隆之, 佐藤 明弘, 松橋 俊夫, 高瀬 圭, 奥本 忠之, 常陸 真, 金田 朋洋, 高橋 昭喜, 遠藤 希之

    日本医学放射線学会学術集会抄録集　66回　S199-S200　2007/02

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

  112. Initial evaluation of dynamic human imaging using F-18-FRP170 as a new PET tracer for imaging hypoxia

    Tomohiro Kaneta, Yoshihiro Takai, Ren Iwata, Takashi Hakamatsuka, Hiroyasu Yasuda, Katsutoshi Nakayama, Yoichi Ishikawa, Shoichi Watanuki, Shozo Furumoto, Yoshihito Funaki, Eiko Nakata, Keiichi Jingu, Michihiko Tsujitani, Masatoshi Ito, Hiroshi Fukuda, Shoki Takahashi, Shogo Yamada

    ANNALS OF NUCLEAR MEDICINE　21　(2)　101-107　2007/02

    DOI： 10.1007/BF03033987 　

    ISSN： 0914-7187

  113. 同一のFDG-PET症例におけるWorkStationの違いによるSUVの変動

    佐々木 悠, 細貝 良行, 小田桐 逸人, 児玉 裕康, 藤田 香, 阿部 養悦, 梁川 功, 金田 朋洋, 福田 寛

    日本放射線技術学会東北部会雑誌　(16)　104-105　2007/01

    Publisher: (公社)日本放射線技術学会-東北支部

  114. Temporal Change in Brain Natriuretic Peptide after Radiotherapy for Thoracic Esophageal Cancer.

    Jingu K Nemoto, K, Kaneta, T Oikawa, M, Ogawa, Y, Ariga H, Takeda, K, Sakayauchi T, Fujimoto, K, Narazaki, K, Takai Y, Nakata E, Fukuda, H, Takahashi, S, Yamada S

    Int J Radiat Oncol Biol Phys.　1-7　2007

    DOI： 10.1016/j.ijrobp.2007.05.054 　

  115. Efficacy of superficial temporal artery-middle cerebral artery anastomosis with routine postoperative cerebral blood flow measurement during the acute stage in childhood moyamoya disease.

    Fujimura M, Kaneta, T, Tominaga T

    Childs Nerv Syst.　1　2007

    DOI： 10.1007/s00381-007-0551-y 　

  116. 食道癌放射線治療に伴う心臓障害の先行指標

    神宮啓一, 小川芳弘, 有賀久哲, 武田 賢, 坂谷内徹, 藤本圭介, 奈良崎覚太朗, 山田章吾, 金田朋洋, 一瀬あずさ, 高橋昭喜, 根本建二, 高井良尋, 仲田栄子

    41　(4)　343-354　2006/12

    Publisher: 放射線生物研究会

    ISSN： 0441-747X

    eISSN： 2186-9766

  117. [18F]標識新規低酸素マーカー[18F]FRP170による脳虚血域中の生存域の検出

    袴塚 崇, 金田 朋洋, 高橋 昭喜, 山田 章吾, 福田 寛, 丸岡 伸, 高井 良尋, 岩田 錬, 辻谷 典彦

    核医学　43　(4)　339-339　2006/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  118. 99m Tc-MIBI SPECT/CTが有用であった副甲状腺癌再発の一例

    佐藤 幸子, 金田 朋洋, 高浪 健太郎, 高橋 昭喜, 山田 章吾, 丸岡 伸, 瀧 靖之, 岡田 賢, 井上 健太郎, 後藤 了以, 木之村 重男, 福田 寛

    核医学　43　(4)　351-351　2006/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  119. FDG-PETにて縦隔リンパ節転移が疑われた結腸直腸癌術後症例の検討

    金田 朋洋, 高浪 健太郎, 高橋 昭喜, 福田 寛

    核医学　43　(4)　352-352　2006/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  120. The utility of F-18-fluorodeoxyglucose positron emission tomography for early diagnosis of radiation-induced myocardial damage

    Keiichi Jingu, Tomohiro Kaneta, Kenji Nemoto, Azusa Ichinose, Minako Oikawa, Yoshihiro Takai, Yoshihiro Ogawa, Eiko Nakata, Toru Sakayauchi, Kenji Takai, Toshiyuki Sugawara, Kakutaro Narazaki, Hiroshi Fukuda, Shoki Takahashi, Shogo Yamada

    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS　66　(3)　845-851　2006/11

    DOI： 10.1016/j.ijrobp.2006.06.007 　

    ISSN： 0360-3016

  121. Usefulness of quantitative gated myocardial perfusion SPECT to evaluate the initial effectiveness of cardiac resynchronization therapy and to predict left ventricular reverse remodeling

    Yuji Wakayama, Minako Oikawa, Yutaka Kagaya, Koji Kumagai, Koji Fukuda, Yoshinao Sugai, Koichiro Sugimura, Tomohiro Kaneta, Hiroshi Fukuda, Hiroaki Shimokawa

    CIRCULATION　114　(18)　637-637　2006/10

    ISSN： 0009-7322

  122. CRT improves abnormal left ventricular wall thickening and remodeling evaluated by quantitative gated myocardial perfusion SPECT

    Wakayama Yuji, Koji Kumagai, Koji Fukuda, Yoshinao Sugai, Koichiro Sugimura, Tomohiro Kaneta, Hiroshi Fukuda, Yutaka Kagaya, Hiroaki Shimokawa

    JOURNAL OF CARDIAC FAILURE　12　(8)　S180-S180　2006/10

    ISSN： 1071-9164

  123. 新規低酸素マーカー18F-FRP170を用いたdynamic tumor imaging

    金田 朋洋, 高井 良尋, 袴塚 崇, 古本 祥三, 石川 洋一, 丸岡 伸, 岩田 錬, 伊藤 正敏, 福田 寛, 高橋 昭喜, 山田 章吾

    核医学　43　(3)　258-258　2006/10

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  124. 【Interventional Radiologyのコツ】 胆道・膵・脾 急性膵炎動注療法

    佐藤明弘, 石橋忠司, 山田隆之, 高瀬圭, 松橋俊夫, 清治和将, 常陸真, 奥本忠之, 金田朋洋, 日向野修, 武田和憲, 高橋昭喜

    臨床放射線　51　(11)　1525-1528　2006/10

    Publisher: 金原出版(株)

    ISSN： 0009-9252

  125. Increase in tumor marker CA19-9 level without evident radiological findings is insufficient for justification of (18)FDG-PET examination

    K. Inoue, K. Okada, Y. Taki, R. Goto, S. Kinomura, T. Kaneta, H. Fukuda

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　33　S83-S83　2006/09

    ISSN： 1619-7070

  126. Evaluation of the relationship between physiological FDG uptake in the heart and age, blood glucose level, fasting period, and hospitalization

    T Kaneta, T Hakamatsuka, K Takanami, T Yamada, K Takase, A Sato, S Higano, S Kinomura, H Fukuda, S Takahashi, S Yamada

    ANNALS OF NUCLEAR MEDICINE　20　(3)　203-208　2006/04

    DOI： 10.1007/BF03027431 　

    ISSN： 0914-7187

  127. PJ-055 Cardiac Resynchronization Therapy Homogenizes Non-uniform Regional Left Ventricular Wall Thickening Evaluated by Quantitative Gated Myocardial Perfusion SPECT(Heart failure, clinical-18 (M) PJ10,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

    Wakayama Yuji, Kumagai Koji, Oikawa Minako, Fukuda Koji, Sugai Yoshinao, Otomo Jun, Shinozaki Tsuyoshi, Kagaya Yutaka, Iguchi Atsushi, Tabayashi Koichi, Kaneta Tomohiro, Fukuda Hiroshi, Shirato Kunio, Shimokawa Hiroaki

    Circulation journal : official journal of the Japanese Circulation Society　70　503-503　2006/03/01

    Publisher: Japanese Circulation Society

    ISSN： 1346-9843

  128. OJ-076 Usefulness of Quantitative Gated Myocardial Perfusion SPECT to Predict Left Ventricular Reverse Remodeling after Cardiac Resynchronization Therapy(Heart failure, clinical-3 (M) OJ13,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

    Wakayama Yuji, Kumagai Koji, Oikawa Minako, Fukuda Koji, Sugai Yoshinao, Otomo Jun, Shinozaki Tsuyoshi, Kagaya Yutaka, Iguchi Atsushi, Tabayashi Koichi, Kaneta Tomohiro, Fukuda Hiroshi, Shirato Kunio, Shimokawa Hiroaki

    Circulation journal : official journal of the Japanese Circulation Society　70　252-253　2006/03/01

    Publisher: Japanese Circulation Society

    ISSN： 1346-9843

  129. OE-283 Diagnostic Usefulness of Delayed Contrast Magnetic Resonance and FDG-PET for Cardiac Sarcoidosis(MRI/MRA-1 (I) OE48,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

    Oikawa Minako, Kagaya Yutaka, Itoh Kenta, Otani Hiroki, Takahashi Jun a, Shinozaki Tsuyoshi, Ichinose Azusa, Kaneta Tomohiro, Fukuda Hiroshi, Takahashi Shoki, Shirato Kunio, Shimokawa Hiroaki

    Circulation journal : official journal of the Japanese Circulation Society　70　219-219　2006/03/01

    Publisher: Japanese Circulation Society

    ISSN： 1346-9843

  130. Prolapsed endometrial cancer: FDG PET/CT findings

    T Kaneta, T Hakamatsuka, T Yamada, A Sato, S Higano, H Fukuda, S Takahashi, S Yamada

    CLINICAL NUCLEAR MEDICINE　31　(3)　180-180　2006/03

    DOI： 10.1097/01.rlu.0000200886.11045.8b 　

    ISSN： 0363-9762

  131. Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non-small-cell lung cancer

    H Yasuda, M Yamaya, K Nakayama, T Sasaki, S Ebihara, A Kanda, M Asada, D Inoue, T Suzuki, T Okazaki, H Takahashi, M Yoshida, T Kaneta, K Ishizawa, S Yamanda, N Tomita, M Yamasaki, A Kikuchi, H Kubo, H Sasaki

    JOURNAL OF CLINICAL ONCOLOGY　24　(4)　688-694　2006/02

    DOI： 10.1200/JCO.2005.04.0436 　

    ISSN： 0732-183X

  132. Changes in regional brain glucose metabolism in Parkinson's disease

    A. Kikuchi, A. Takeda, N. Sugeno, M. Kobayashi, T. Hasegawa, K. Suzuki, Y. Hosokai, K. Hirayama, T. Ishioka, Y. Sawada, K. Okada, E. Mori, T. Kaneta, S. Takahashi, H. Fukuda, Y. Itoyama

    MOVEMENT DISORDERS　21　S516-S516　2006

    ISSN： 0885-3185

  133. Cerebral glucose metabolism in each patient with Parkinson's disease and its correlation to cognitive impairment

    Y. Hosokai, K. Suzuki, T. Atsushi, K. Hirayama, T. Ishioka, Y. Nishio, Y. Sawada, K. Okada, S. Kinomura, T. Kaneta, Y. Itoyama, S. Takahashi, H. Fukuda, E. Mori

    MOVEMENT DISORDERS　21　S626-S626　2006

    ISSN： 0885-3185

  134. PET/CTにおける吸収補正の基礎的検討

    大下 亮介, 細貝 良行, 小田桐 逸人, 塚原 智子, 廣川 文人, 阿部 養悦, 梁川 功, 佐藤 多智雄, 福田 寛, 金田 朋洋

    日本放射線技術学会東北部会雑誌　(15)　120-121　2006/01

    Publisher: (公社)日本放射線技術学会-東北支部

  135. Dynamic Human Imaging using 18F-FRP170 as a New PET Tracer for Imaging Hypoxia

    Kaneta T., Takai Y., Iwata R., Hakamatsuka T., Yasuda H., Nakayama K., Ishikawa Y., Watanuki S., Furumoto S., Funaki Y., Nakata E., Jingu K., Tsujitani M., Ito M., Fukuda H., Takahashi S., Yamada S.

    CYRIC annual report　2006　109-112　2006

    Publisher: Cyclotron and Radioisotope Center, Tohoku University

  136. 【期待されるFDG以外の腫瘍PETイメージング製剤】 新低酸素細胞イメージング剤[18F]FRP-170の開発と臨床応用 (臨床放射線)

    高井良尋, 金田朋洋, 袴塚崇, 仲田栄子, 山田章吾, 岩田錬, 船木善仁, 石川洋一, 辻谷典彦

    臨床放射線　51　(7)　837-843　2006

  137. FDG PET in solitary metastastic/secondary tumor of the kidney: A report of three cases and a review of the relevant literature

    T Kaneta, T Hakamatsuka, T Yamada, K Takasa, A Sato, S Higano, S Kinomura, H Fukuda, S Takahashi, S Yamada

    ANNALS OF NUCLEAR MEDICINE　20　(1)　79-82　2006/01

    ISSN： 0914-7187

  138. PET検査用新規低酸素マーカー18F-FRP170の臨床応用

    金田 朋洋, 袴塚 崇, 高橋 昭喜, 神宮 啓一, 菅原 俊幸, 山田 章吾, 高井 良尋, 丸岡 伸, 岩田 錬, 石川 洋一, 船木 善仁, 工藤 幸司, 仲田 栄子, 古本 祥三, 福田 寛

    核医学　42　(4)　414-414　2005/12

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  139. 空腹時FDG PET検査における心筋集積

    金田 朋洋, 袴塚 崇, 高橋 昭喜, 山田 章吾, 丸岡 伸, 福田 寛

    核医学　42　(4)　429-429　2005/12

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  140. 期待されるFDG以外の腫瘍PETイメージング製剤 新低酸素細胞イメージング剤[18F]FRP-170の開発と臨床応用

    高井 良尋, 金田 朋洋, 袴塚 崇, 岩田 錬, 船木 善仁, 古本 祥三, 仲田 栄子, 工藤 幸司, 山田 章吾

    核医学　42　(3)　260-260　2005/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  141. PET検査用新規低酸素マーカー18F-FRP170の臨床応用

    金田 朋洋, 高井 良尋, 袴塚 崇, 石川 洋一, 仲田 栄子, 古本 祥三, 工藤 幸司, 岩田 錬, 伊藤 正敏, 福田 寛, 山田 章吾

    核医学　42　(3)　307-307　2005/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  142. Preliminary Results of Clinical PET Studies Using a New Hypoxia Marker, 18F-FRP170

    T. Kaneta, Y. Takai, T. Hakamatsuka, E. Nakata, S. Furumoto, R. Iwata, M. Ito, H. Fukuda, M. Tsujitani, S. Takahashi, S. Yamada

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　32　S80-S80　2005/09

    ISSN： 1619-7070

  143. [18F]標識2-nitroimidazole誘導体;[18F]FRP170による脳虚血の画像化に関する基礎研究(組織学的な検討)

    袴塚 崇, 金田 朋洋, 丸岡 伸, 高橋 昭喜, 高井 良尋, 山田 章吾, 福田 寛, 古本 祥三, 岩田 錬, 辻谷 典彦

    核医学　42　(2)　133-133　2005/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  144. 外部線源を用いたトランスミッション法における被曝線量の基礎的検討(第32回秋季学術大会放射線防護管理関連演題発表後抄録, <特集>第61回総会学術大会放射線防護分科会)

    塚原 智子, 佐藤 多智雄, 小田桐 逸人, 小野 勝範, 細貝 良行, 阿部 養悦, 佐々木 正寿, 金田 朋洋, 福田 寛

    放射線防護分科会会誌　20　(0)　44-44　2005

    Publisher: 公益社団法人 日本放射線技術学会

    DOI： 10.18973/protectionjsrt.20.0_44 　

    ISSN： 1345-3246

  145. PET専用装置とcoincidence機能搭載型CT-SPECT装置の基礎的検討

    小野 勝範, 阿部 養悦, 細貝 良行, 小田桐 逸人, 塚原 智子, 佐々木 正寿, 金田 朋洋, 佐藤 多智雄, 福田 寛

    日本放射線技術学会東北部会雑誌　(14)　90-92　2005/01

    Publisher: (公社)日本放射線技術学会-東北支部

  146. Scatter and cross-talk correction for one-day acquisition of I-123-BMIPP and Tc-99m-tetrofosmin myocardial SPECT

    T Kaneta, H Kurihara, T Hakamatsuka, H Ito, S Maruoka, H Fukuda, S Takahashi, S Yamada

    ANNALS OF NUCLEAR MEDICINE　18　(8)　647-652　2004/12

    ISSN： 0914-7187

  147. [18F]標識2-nitroimidazole誘導体 [18F]FRP170による脳虚血の画像化に関する基礎研究 脳血流および糖代謝との相関

    袴塚 崇, 金田 朋洋, 丸岡 伸, 高橋 昭喜, 高井 良尋, 山田 章吾, 福田 寛, 古本 祥三, 岩田 錬, 辻谷 典彦

    核医学　41　(4)　430-430　2004/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  148. CTを用いたガリウムSPECTの吸収補正 3種のエネルギーピークに対応した補正マップを用いて

    金田 朋洋, 栗原 英之, 袴塚 崇, 伊藤 浩, 丸岡 伸, 福田 寛, 高橋 昭喜, 山田 章吾

    核医学　41　(3)　342-342　2004/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  149. [18F]標識新規放射線マーカー [18F]FRP170による脳虚血の画像化に関する基礎研究

    袴塚 崇, 金田 朋洋, 高橋 昭喜, 高井 良尋, 山田 章吾, 丸岡 伸, 古本 祥三, 岩田 錬, 辻谷 典彦

    核医学　41　(3)　350-350　2004/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  150. Imaging cerebral ischemia using a new F-18-labeled 2-nitroimidazole analog, [F-18]FRP-170.

    T Hakamatsuka, Y Takai, T Kaneta, S Takahashi, S Yamada, S Furumoto, R Iwata, M Tsujitani

    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING　31　S255-S255　2004/08

    ISSN： 1619-7070

  151. Usefulness of asialoglycoprotein receptor imaging for the evaluation of liver metastasis of neuroblastoma

    T Kaneta, T Hakamatsuka, H Ito, S Maruoka, H Fukuda, S Takahashi, S Yamada

    ANNALS OF NUCLEAR MEDICINE　18　(4)　355-358　2004/06

    ISSN： 0914-7187

  152. [18F]標識新規低酸素マーカー [18F]FRP170による脳虚血の画像化に関する基礎研究

    袴塚 崇, 金田 朋洋, 高橋 昭喜, 高井 良尋, 山田 章吾, 丸岡 伸, 和田 裕明, 結城 雅弘, 船木 善仁, 岩田 錬, 井戸 達雄, 辻谷 典彦

    核医学　41　(2)　172-172　2004/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  153. Error analysis of measured cerebral vascular response to acetazolamide stress by I-123-IMP autoradiographic method with single photon emission computed tomography: Errors due to distribution volume of I-123-IMP

    H Ito, K Inoue, R Goto, S Kinomura, T Sato, T Kaneta, K Sato, H Fukuda

    ANNALS OF NUCLEAR MEDICINE　18　(3)　221-226　2004/05

    ISSN： 0914-7187

  154. PET 専用装置と coincidence 機能搭載型 CT-SPECT 装置の 基礎的検討 (日本放射線技術学会 東北部会 部会雑誌)

    小野勝範, 阿部養悦, 細貝良行, 小田桐逸人, 塚原, 智子, 佐々木正寿, 金田 朋洋, 佐藤多智雄, 福田寛

    日本放射線技術学会 東北部会 部会雑誌　14　(13)　167-169　2004/01

    Publisher: (公社)日本放射線技術学会-東北支部

  155. 外部線源を用いたトランスミッション法における被曝線量の基礎的検討

    塚原智子, 小田桐逸人, 小野勝範, 細貝良行, 阿部養悦, 佐々木正寿, 佐藤多智雄, 福田寛, 金田朋洋

    日本放射線技術学会雑誌　60　(9)　1234-1235　2004

    Publisher: (公社)日本放射線技術学会

    DOI： 10.6009/jjrt.KJ00003174442 　

    ISSN： 0369-4305

    eISSN： 1881-4883

  156. 脳血流定量測定に用いる放射性薬剤の比較検討

    小田桐逸人, 阿部養悦, 小野勝範, 細貝良行, 塚原智子, 佐藤多智雄, 福田寛, 伊藤浩, 金田朋洋

    日本放射線技術学会雑誌　60　(9)　1236-1237　2004

    Publisher: (公社)日本放射線技術学会

    DOI： 10.6009/jjrt.KJ00003174452 　

    ISSN： 0369-4305

    eISSN： 1881-4883

  157. Tetrofosmin及びBMIPP心筋SPECT同日収集における散乱線・クロストーク補正

    金田 朋洋, 袴塚 崇, 丸岡 伸, 高橋 昭喜, 山田 章吾, 福田 寛, 栗原 英之

    核医学　40　(4)　495-495　2003/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  158. Biomarkers in subjects with amnestic mild cognitive impairment

    M Maruyama, H Arai, M Ootsuki, N Okamura, T Matsui, H Sasaki, T Yamazaki, T Kaneta

    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY　51　(11)　1671-1672　2003/11

    DOI： 10.1046/j.1532-5415.2003.515241.x 　

    ISSN： 0002-8614

  159. 同時計数対応型ガンカマメラによる担癌患者のF-18 FDGイメージ PET装置との病巣検出率の比較

    袴塚 崇, 金田 朋洋, 山口 慶一郎, 栗原 英之, 阿部 養悦, 山崎 哲郎, 福田 寛, 伊藤 正敏, 高橋 昭喜

    核医学　40　(3)　360-360　2003/08

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  160. 褐色細胞腫 良性・悪性の鑑別はどうするか 放射線科の立場より

    山崎 哲郎, 中村 保宏, 金田 朋洋, 小山 周樹, 丸岡 伸, 石橋 忠司, 高橋 昭喜

    日本内分泌学会雑誌　79　(1)　59-59　2003/04

    Publisher: (一社)日本内分泌学会

    ISSN： 0029-0661

  161. 放射性低酸素マーカーの循環器領域への応用 (放射線生物研究)

    金田朋洋, 高井良尋, 加賀谷豊, 山根由理子, 和田裕明, 結城雅弘, 岩田錬, 井戸達夫, 辻谷典彦, 丸岡伸, 高橋昭喜, 山田章吾

    放射線生物研究　38　(2)　155-167　2003

  162. 虚血下生存心筋の最もよい指標は,脂肪酸代謝,糖代謝,或いは低酸素マーカーのうちどれか? 低酸素マーカーとしての新しい放射性物質標識2-nitroimidazoleアナログの実験研究

    金田朋洋, 高井良尋, 加賀谷豊, 山根由理子, 和田裕明, 結城雅弘, 岩田錬, 井戸達夫, 辻谷典彦, 丸岡伸, 高橋昭喜, 山田章吾

    東北医学雑誌　114　(1)　71-73　2002/08

    Publisher: 東北医学会

    ISSN： 0040-8700

  163. 担癌患者の18F-FDGイメージング:ガンマカメラとPET装置の病巣検出率の比較

    袴塚 崇, 坂谷内 徹, 金田 朋洋, 山崎 哲郎, 高橋 昭喜, 小田桐 逸人, 阿部 養悦, 福田 寛, 山口 慶一郎, 伊藤 正敏

    核医学　39　(2)　185-185　2002/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  164. 同時計数回路を用いた対向型ガンマカメラのポジトロンイメージングに関する性能評価

    金田朋洋, 山口慶一郎, 栗原英之, 阿部養悦, 山崎哲郎, 袴塚崇, 坂谷内徹, 高井良尋, 丸岡伸, 木之村重男, 福田寛, 伊藤正敏, 高橋昭喜, 山田章吾

    核医学　39　(1)　47-53　2002/02

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  165. Idiopathic colonic varicesより大量下部消化管出血をきたした1例

    古田 進, 金田 朋洋, 麦倉 俊司, 齋藤 昌宏, 清水 拓也, 寺島 秀夫, 櫻井 直, 平山 克, 嵯峨 知生, 高橋 廣己

    日本医学放射線学会雑誌　62　(1)　43-43　2002/01

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  166. Imaging of ischemic but viable myocardium using a new F-18-labeled 2-nitroimidazole analog, F-18-FRP170

    T Kaneta, Y Takai, Y Kagaya, Y Yamane, H Wada, M Yuki, R Iwata, M Tsujitani, S Takahashi, S Yamada

    JOURNAL OF NUCLEAR MEDICINE　43　(1)　109-116　2002/01

    ISSN： 0161-5505

  167. 副腎癌にI-131 adosterolは集積しないか?

    山崎 哲郎, 金田 朋洋, 高橋 昭喜, 丸岡 伸, 山田 章吾, 阿部 養悦, 窪田 和雄

    核医学　38　(5)　639-639　2001/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  168. [18F]標識した新しい2-nitroimidazole誘導体,[18F]FRP170による虚血心筋中生存域の検出

    金田朋洋, 高井良尋, 加賀谷豊, 山根由理子, 和田裕明, 結城雅弘, 岩田錬, 井戸達夫, 辻谷典彦, 丸岡伸, 高橋昭喜, 山田章吾

    東北医学雑誌　113　(1)　84-86　2001/08

    Publisher: 東北医学会

    ISSN： 0040-8700

  169. 副腎癌の1例

    坂谷内 徹, 山崎 哲郎, 金田 朋洋, 津田 雅志, 間島 一浩, 山田 隆之, 齋藤 春夫, 石橋 忠司, 高橋 昭喜, 山田 章吾

    日本医学放射線学会雑誌　61　(6)　314-314　2001/05

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

  170. 同時計数回路を用いたガンマカメラによるpositron収集

    阿部 養悦, 小田切 逸人, 松崎 智子, 金田 朋洋, 山崎 哲郎, 高橋 昭喜, 山田 章吾, 丸岡 伸, 山口 慶一郎, 伊藤 正敏, 木之村 重男, 福田 寛, 栗原 英之

    核医学　38　(2)　176-176　2001/03

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  171. 心サルコイドーシスの核医学検査所見

    山崎 哲郎, 金田 朋洋, 高橋 昭喜, 山田 章吾, 丸岡 伸, 阿部 養悦

    核医学　38　(2)　173-173　2001/03

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  172. 【第30回放射線による制癌シンポジウム 治療効果比向上への新しい展開】 Tumor heterogeneityへの新しい対応 低酸素細胞の画像化 18F化RP-170([18F]FRP-170)による低酸素細胞画像化に関する基礎研究 (癌の臨床)

    高井良尋, 金田朋洋, 梅津篤志, 袴塚崇, 奥本忠之, 村田隆紀, 高井憲司, 藤本圭介, 山田章吾, 和田裕明, 結城雅弘, 船木善仁, 岩田錬, 井戸達夫, 辻谷典彦

    癌の臨床　47　(1)　59-63　2001

  173. [18F]標識2-nitroimidazole誘導体 [18F]RP170による虚血心筋の評価

    金田 朋洋, 高井 良尋, 山崎 哲郎, 丸岡 伸, 高橋 昭喜, 山田 章吾, 加賀谷 豊, 山根 由理子, 結城 雅弘, 和田 裕明

    核医学　37　(6)　703-703　2000/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  174. 脳腫瘍術後の201Tl SPECT所見の検討

    山崎 哲郎, 金田 朋洋, 高橋 昭喜, 山田 章吾, 丸岡 伸, 阿部 養悦

    核医学　37　(6)　700-701　2000/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  175. 新しい[18F]標識nitroimidazole誘導体([18F]RP170)による虚血心筋の評価

    金田 朋洋, 高井 良尋, 山崎 哲郎, 丸岡 伸, 高橋 昭喜, 山田 章吾, 船木 善仁, 岩田 錬, 井戸 達雄

    核医学　37　(5)　572-572　2000/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  176. 副腎腫瘍に対するI-131 adosterol副腎シンチグラフィ・CT・MRIの診断能の比較

    山崎 哲郎, 金田 朋洋, 丸岡 伸, 阿部 養悦, 高橋 昭喜, 山田 章吾

    核医学　37　(5)　521-521　2000/09

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  177. Correlation of pulmonary perfusion volume analysis with pulmonary function in emphysema

    T. Kaneta, T. Yamazaki, S. Maruoka, Y. Abe, Y. Takai, S. Takahashi, S. Yamada

    Kakuigaku　37　359-364　2000/07/01

    ISSN： 0022-7854

  178. 胆道閉鎖症術後症例の肝GAS SPECT

    山崎 哲郎, 金田 朋洋, 箕浦 衣里子, 野宮 琢磨, 高橋 昭喜, 山田 章吾, 丸岡 伸

    核医学　37　(4)　367-367　2000/07

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  179. リンパ増殖性肺疾患の1例

    久保園 正樹, 田村 亮, 間島 一浩, 津田 雅視, 金田 朋洋, 奥本 忠之, 斎藤 美穂子, 石橋 忠司, 高橋 昭喜, 山田 章吾

    日本医学放射線学会雑誌　60　(8)　457-457　2000/07

    Publisher: (公社)日本医学放射線学会

    ISSN： 0048-0428

    eISSN： 1347-7951

  180. 肺血流容積定量による簡便な肺機能評価 肺気腫患者を対象に

    金田朋洋, 山崎哲郎, 丸岡伸, 阿部養悦, 高井良尋, 高橋昭喜, 山田章吾

    核医学　37　(4)　359-364　2000/07

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  181. 【びまん性肝疾患の画像診断】 びまん性代謝性疾患の画像診断

    山田 隆之, 金田 朋洋, 石橋 忠司, 田村 亮, 高橋 昭喜

    臨床画像　16　(1)　88-96　2000/01

    Publisher: (株)メジカルビュー社

    ISSN： 0911-1069

  182. 肝転移巣に99mTc-MDPが集積した前立腺肉腫の1例

    藤本 圭介, 金田 朋洋, 山崎 哲郎, 高橋 昭喜, 山田 章吾, 丸岡 伸

    核医学　36　(9)　1038-1038　1999/12

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  183. 123I-Iomazenil brain SPECTの定量測定 モヤモヤ病患者の対象に

    金田朋洋, 山崎哲郎, 丸岡伸, 阿部養悦, 高橋昭喜, 山田章吾

    核医学　36　(9)　1007-1012　1999/12

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  184. Compartment analysis of123I-Iomazenil brain SPECT in patients with moyamoya disease

    Tomohiro Kaneta, Tetsuro Yamazaki, Shin Maruoka, Yoetsu Abe, Shoki Takahashi, Shogo Yamada

    Kakuigaku　36　(9)　1011-1012　1999/12/01

    ISSN： 0022-7854

  185. 神経芽細胞腫に対する骨・ガリウムシンチグラフィ MIBGシンチグラフィと対比して

    山崎 哲郎, 金田 朋洋, 丸岡 伸, 高橋 昭喜, 山田 章吾

    核医学　36　(6)　648-648　1999/08

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  186. 先天性胆道閉鎖症患者における肝99mTc-GSAシンチグラフィと99mTc-スズコロイドシンチグラフィの比較

    金田 朋洋, 山崎 哲郎, 阿部 養悦, 丸岡 伸, 高橋 昭喜, 山田 章吾

    核医学　36　(6)　646-646　1999/08

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  187. Cumulative Survival Rates after Radioiodine Therapy for Differentiated Thyroid Cancer

    Shin MARUOKA, Tetsuro YAMAZAKI, Tomohiro KANETA, Masayuki ZUGUCHI, Shoki TAKAHASHI, Shogo YAMADA, Department of Radiological Technology College of Medical Sciences Tohoku University, Department of Radiology Tohoku University school of Medicine, Department of Radiology Tohoku University school of Medicine, Department of Radiological Technology College of Medical Sciences Tohoku University, Department of Radiology Tohoku University school of Medicine, Department of Radiology Tohoku University school of Medicine

    8　(2)　219-224　1999/07/31

    ISSN： 0917-4435

  188. 分化型甲状腺癌に対する131I治療後の累積生存率

    丸岡伸, 山崎哲郎, 金田朋洋, 洞口正之, 高橋昭喜, 山田章吾

    東北大学医療技術短期大学部紀要　8　(2)　219-224　1999/07

    Publisher: 東北大学医療技術短期大学部

    ISSN： 0917-4435

  189. 先天性横隔膜ヘルニア患者の肺換気・血流シンチグラフィ

    金田 朋洋, 山崎 哲郎, 斎藤 美穂子, 高橋 昭喜, 山田 章吾, 丸岡 伸

    核医学　36　(4)　385-385　1999/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  190. 腎IVR前後の腎シンチグラフィ 腎AVMの2例について

    袴塚 崇, 金田 朋洋, 山崎 哲郎, 高橋 昭喜, 山田 章吾, 丸岡 伸

    核医学　36　(4)　387-387　1999/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  191. 副腎シンチグラフィにおける左右差の再検討

    山崎 哲郎, 金田 朋洋, 袴塚 崇, 斎藤 美穂子, 高橋 昭喜, 山田 章吾, 丸岡 伸

    核医学　36　(4)　387-387　1999/05

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

    eISSN： 2189-9932

  192. transdiaphragmatic shuntを呈した肝硬変の1例

    箕浦 衣里子, 山崎 哲郎, 金田 朋洋, 袴塚 崇, 高橋 昭喜, 山田 章吾, 丸岡 伸

    核医学　35　(9)　961-961　1998/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  193. 131I-adosterolが集積した褐色細胞腫の1例

    袴塚 崇, 山崎 哲郎, 金田 朋洋, 箕浦 衣里子, 高橋 昭喜, 山田 章吾, 丸岡 伸, 木村 伯子

    核医学　35　(9)　961-962　1998/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

  194. モヤモヤ病に対するIomazenil SPECTの定量的検討

    金田 朋洋, 山崎 哲郎, 丸岡 伸, 高橋 昭喜, 山田 章吾

    核医学　35　(9)　957-957　1998/11

    Publisher: (一社)日本核医学会

    ISSN： 0022-7854

Show all ︎Show first 5

Presentations 18

  1. 3D-SSP変法を用いたBF-227アミロイドPET解析

    日本医学放射線学会北日本地方会　2011

  2. 3D-SSP変法によるBF-227を用いたアミロイドPET解析

    日本核医学会総会　2011

  3. 3D-SSP変法を用いたBF-227アミロイドPET解析

    日本医学放射線学会北日本地方会　2011

  4. 3D-SSP変法によるBF-227を用いたアミロイドPET解析

    日本核医学会総会　2011

  5. Dementia Clinical Trials with Longitudinal FDG PET: Improved Statistical Power Using Intra-subject Registration

    Society of Nuclear Medicine 2009 Annual Meeting　2009

  6. Dementia Clinical Trials with Longitudinal FDG PET: Improved Statistical Power Using Intra-subject Registration

    Society of Nuclear Medicine 2009 Annual Meeting　2009

  7. Pacemaker induced artifacts on PET/CT

    世界心臓核医学会（ICNC)　2007

  8. 低酸素マーカー18F-FRP170を用いたニトログリセリン治療に伴う腫瘍集積評価

    米国核医学会（SNM)　2007

  9. Pacemaker induced artifacts on PET/CT

    世界心臓核医学会（ICNC)　2007

  10. 低酸素マーカー18F-FRP170を用いたニトログリセリン治療に伴う腫瘍集積評価

    米国核医学会（SNM)　2007

  11. Dynamic PET imaging of tumor hypoxia using [F18]FRP170 in cancer patients

    米国核医学会（SNM)　2006

  12. Evaluation of thoracic lymph nodes metastases suspected on FDG PET in patients after surgery for colorectal cancer

    世界核医学会（WCNMB）　2006

  13. Dynamic PET imaging of tumor hypoxia using [F18]FRP170 in cancer patients

    米国核医学会（SNM)　2006

  14. Evaluation of thoracic lymph nodes metastases suspected on FDG PET in patients after surgery for colorectal cancer

    世界核医学会（WCNMB）　2006

  15. In vivo evaluation of [18F]FRP170 as a new marker for imaging hypoxia with positron emission tomography in healthy volunteers

    米国核医学会（SNM)　2005

  16. Preliminary results of clinical PET studies using a new hypoxia marker, [18F]FRP170

    ヨーロッパ核医学会（EANM)　2005

  17. In vivo evaluation of [18F]FRP170 as a new marker for imaging hypoxia with positron emission tomography in healthy volunteers

    米国核医学会（SNM)　2005

  18. Preliminary results of clinical PET studies using a new hypoxia marker, [18F]FRP170

    ヨーロッパ核医学会（EANM)　2005

Show all Show first 5

Research Projects 11

  1. Elucidation of the pathophysiology of Alzheimer's disease by a novel tau-specific PET tracer, [F18]SNFT-1

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (B)

    Institution: Tohoku University

    2023/04/01 - 2026/03/31

  2. Development of a CYP11B2 probe for imaging aldosterone-producing adenomas with high sensitivity.

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (B)

    Institution: Tohoku University

    2023/04/01 - 2026/03/31

  3. Development of a CYP11B2 probe for imaging aldosterone-producing adenomas with high sensitivity.

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (B)

    Institution: Tohoku University

    2023/04/01 - 2026/03/31

  4. Pathophysiology of Alzheimer's disease using a novel tau-specific PET tracer, [F18]SNFT-1

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (B)

    Institution: Tohoku University

    2023/04/01 - 2026/03/31

  5. Optimization of voxel-based statistical analyses for amyloid PET of Alzheimer's disease

    KANETA Tomohiro, OKAMURA Nobuyuki

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (C)

    Institution: Tohoku University

    2012/04/01 - 2015/03/31

    More details Close

    We performed voxel-based statistical analyses for amyloid PET with BF-227 using both SPM and 3D-SSP, and compared the results in order to explore the optimal methods for the analyses. Differences in results were seen in 24% of normal subjects, 45% of MCI patients, and 68% of AD patients. Errors were often seen in the results of anatomical standardization. The use of blood flow images for 3D-SSP, and scalping for SPM might enable to reduce errors.

  6. Clarification of mechanism of renoprotective effect by renal oxygen metabolism and development of imaging method for renal function evaluation.

    MORI Takefumi, ITO Sadayoshi, TAKAHASHI Nobuyuki, KANETA Tomohiro

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Challenging Exploratory Research

    Institution: Tohoku University

    2011 - 2012

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    Hypoxia induced mitochondrial oxidative stress in renal medullary thick ascending limb of loop of Henle. Treatment with Mito-TEMPO significantly attenuated the reduction of renal medullary blood flow induced by ischemia/reperfusion. We established methods to evaluate renal function with [^<15>O]H_2O-PET and [^<18>F]FRP-170-PET. We created conditional prolyl hydroxylase (PHD) knockout mice, and measured the response of renal medullary blood flow in those mice. These results indicated that hypoxia could exacerbate renal injury though increase of mitochondrial oxidative stress and following reduction of renal medullary blood flow.

  7. Optimization and standardization of longitudinal brain image analysis for dementia

    KANETA Tomohiro

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Young Scientists (B)

    Institution: Tohoku University

    2010 - 2011

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    The aim of this study was to optimize and standardize the analysis method for the longitudinal brain image evaluation for dementia. Neurostat program was used for 3D-SSP analyses. As the index for the evaluation, A)posterior cingulate cortex (PCC), and B)PCC+ parietal and tempotal lobes showed relatively small sample size for the detection of the changes over time. However, these values seem to be large for the clinical trials of the new drugs for Alzheimer's disease. Further investigation is required.

  8. Research on the usefulness of newly developed hypoxia imaging agent for PET for a tailor-made treatment of cancer

    TAKAI Yoshihiro, YAMAYA Mutsuo, HOSHIKAWA Yasushi, KANETA Tomohiro, NAKATA Eiko

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Scientific Research (B)

    2008 - 2011

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    [18F]FRP170,1-(2-fluoro-1-[hydroxymethyl]ethoxy)methyl-2-nitroimidazole, is a new PET tracer for imaging hypoxia which was developed by the principal researcher and his colleagues of this Grant-in-Aid for Scientific research. The usefulness of [18F]FRP-170 for a treatment for a tailor-made treatment of cancer was investigated by looking at the relationship between the rate of FRP-170 uptake of tumor and the radiation responsiveness, the hypoxia related gene expression in the resected lung cancer, benign or malignant glioma, and O2 partial pressure in the malignant glioma. The results obtained from these clinical investigation were all positive for the usefulness of the drug. [18F]FRP-170, therefore, is strongly suggested to be a promising new hypoxia marker to establish a tailor-made-treatment of cancer.

  9. Development and evaluation of new PET tracer for cancer imaglng, especially for the prediction of therapeutic effects.

    KANETA Tomohiro

    Offer Organization: Japan Society for the Promotion of Science

    System: Grants-in-Aid for Scientific Research

    Category: Grant-in-Aid for Young Scientists (B)

    Institution: Tohoku University

    2007 - 2008

  10. 新しい原理(低酸素細胞のPETイメージング)に基づく心筋虚血評価法の開発

    加賀谷 豊, 杉村 宏一郎, 高井 良尋, 岩田 錬, 金田 朋洋

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 萌芽研究

    Institution: 東北大学

    2007 - 2008

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    冠動脈造影による冠動脈の狭窄度の評価を行っただけでは、適切な症例に適切に冠動脈インターベンションあるいは冠動脈バイパス術を行うことはできない。従って、主として画像診断による心筋バイアビリティの評価が極めて重要である。FDGを用いたポジトロン断層撮影(PET)はこの目的に頻繁に使用されるが、患者のインスリン分泌能あるいは心筋のインスリン感受性の影響を受けることから、新しいイメージング剤の開発が強く望まれている。東北大学では放射線増感剤1-[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl-2-nitroimidazole(以下RP-170)のフッ素誘導体を^<18>Fで標識した新しい低酸素細胞イメージング剤[^<18>F]FRP-170の合成に成功している。本研究において、[^<18>F]FRP-170を用いたPET検査が心筋バイアビリティの評価に有用であるか否かを検証した。冠動脈に有意狭窄病変がある安定した冠動脈疾患患者において、[^<18>F]FRP-170を用いた運動負荷心臓PETを行った。自転車エルゴメータによる多段階負荷によりエンドポイントに達したところで、予め確保しておいた静脈ラインから[^<18>F]FRP-1705mCiを注射した。注射後約30秒間は運動を続け、PETの撮像は[^<18>F]FRP-170投与後、5分間隔で1時間後まで行った。以前我々が報告したラットを用いた動物実験の結果とは異なり、[^<18>F]FRP-170の集積に関して虚血領域と非虚血領域の違いが明瞭でなかった。今後、さらに投与方法を変更することや心筋虚血のより強い症例において検討を重ねる必要があると考える。

  11. 新しい放射性低酸素マーカー18F-FRP170による虚血心筋中の生存心筋検出

    金田 朋洋

    Offer Organization: 日本学術振興会

    System: 科学研究費助成事業

    Category: 若手研究(B)

    Institution: 東北大学

    2004 - 2005

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    前年度の結果を踏まえて二核種オートラジオグラフィの実験プロトコルを確定し、心筋虚血モデルラットを用いた実験を施行した。行った実験はFRP170と血流製剤IAP、糖代謝製剤Deoxyglucose(DG)、脂肪酸代謝製剤BMIPPの比較である。さらにstreptozotocin投与により作成した糖尿病モデルラットを用いて、FRP170とDGの比較も行った。FRP170が短半減期のF-18で標識されているのに対し、他の三製剤はI-125やC-14といった長半減期の核種で標識されている。この半減期の差を利用して、同一切片から2つの画像が得られるため、詳細な比較検討が可能である。まず、FRP170と血流あるいは脂肪酸代謝の比較では、血流あるいは脂肪酸代謝低下域中にFRP170の高集積域と低集積域が認められた。糖代謝製剤との比較では、FRP170とDGの分布は一見類似していたが、FRP170の方が画像コントラストが良好で高集積域の範囲も広かった。一方、糖尿病モデルを用いた検討では、糖代謝製剤DGによる画像は集積やコントラストが著明に低下したのに対し、FRP170の画像には明らかな差は認めなかった。以上より、FRP170を用いることで虚血領域を生存域と壊死域に分別することができ、さらに糖尿病下においても同等の画像コントラストが得られることが立証された。臨床的に虚血下生存心筋の検出に関しては糖代謝製剤FDGを用いたPET検査がgold standardとされているが、低酸素マーカーFRP170を用いることで、同等の検出能が期待でき、さらに糖尿病患者においても安定した検査が可能となることが示唆された。糖尿病は虚血性心疾患の大きなリスクファクターの一つであるが、FDG検査では評価が困難である。FRP170を用いることで虚血心筋をさらに正確に評価できることが期待される。

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Works 6

  1. Alzheimer病のPET診断における縦断的評価指標の検討

    2008 - 2010

  2. Alzheimer病のPET診断における縦断的評価指標の検討

    2008 - 2010

  3. 腫瘍血管を標的としたPET用分子イメージング剤の開発とがん治療効果予測・治療効果への応用

    2006 - 2008

  4. 腫瘍血管を標的としたPET用分子イメージング剤の開発とがん治療効果予測・治療効果への応用

    2006 - 2008

  5. [18F]標識した新2-nitroimidazole誘導体[18F]FRP170の有用性に関する基礎研究

    2000 - 2001

  6. [18F]標識した新2-nitroimidazole誘導体[18F]FRP170の有用性に関する基礎研究

    2000 - 2001

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