東北メディカル・メガバンク機構

研究キーワード

生命情報システム科学 ,数理生物物理非線形科学反応拡散系 ,Reaction-diffusion computing ,Nonlinear Science ,Mathematical Biophysics

研究分野

ライフサイエンス / 生物物理学 /
自然科学一般 / 生物物理、化学物理、ソフトマターの物理 /
自然科学一般 / 数理物理、物性基礎 /
ライフサイエンス / ゲノム生物学 /

論文

Wide-Targeted Metabolome Analysis Identifies Potential Biomarkers for Prognosis Prediction of Epithelial Ovarian Cancer.

Eiji Hishinuma Muneaki Shimada Naomi Matsukawa Daisuke Saigusa Bin Li Kei Kudo Keita Tsuji Shogo Shigeta Hideki Tokunaga Kazuki Kumada Keigo Komine Hidekazu Shirota Yuichi Aoki Ikuko N Motoike Jun Yasuda Kengo Kinoshita Masayuki Yamamoto Seizo Koshiba Nobuo Yaegashi

Toxins 13(7) 2021年6月

Epithelial ovarian cancer (EOC) is a fatal gynecologic cancer, and its poor prognosis is mainly due to delayed diagnosis. Therefore, biomarker identification and prognosis prediction are crucial in EOC. Altered cell metabolism is a characteristic ...

Chronic Hypercapnic Respiratory Failure in an Adult Patient with Silver-Russell Syndrome.

Mariko Hakamata Satoshi Hokari Yasuyoshi Ohshima Masayo Kagami Sakae Saito Ikuko N Motoike Taiki Abe Nobumasa Aoki Masachika Hayashi Satoshi Watanabe Toshiyuki Koya Toshiaki Kikuchi

Internal medicine (Tokyo, Japan) 60(12) 1921-1926 2021年6月

A 31-year-old woman who was clinically diagnosed with Silver-Russell syndrome (SRS) in childhood was admitted with complaints of dyspnea. She had hypercapnic respiratory failure accompanied by nocturnal hypoventilation. Computed tomography reveale...

Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs.

Mika Sakurai-Yageta Kazuki Kumada Chinatsu Gocho Satoshi Makino Akira Uruno Shu Tadaka Ikuko N Motoike Masae Kimura Shin Ito Akihito Otsuki Akira Narita Hisaaki Kudo Yuichi Aoki Inaho Danjoh Jun Yasuda Hiroshi Kawame Naoko Minegishi Seizo Koshiba Nobuo Fuse Gen Tamiya Masayuki Yamamoto Kengo Kinoshita

Journal of biochemistry 2021年5月

Ethnic-specific SNP arrays are becoming more important to increase the power of genome-wide association studies in diverse population. In the Tohoku Medical Megabank Project, we have been developing a series of Japonica Arrays (JPA) for genotyping...

GWAS Identified IL4R and the Major Histocompatibility Complex Region as the Associated Loci of Total Serum IgE Levels in 9,260 Japanese Individuals.

Kosuke Shido Kaname Kojima Matsuyuki Shirota Kenshi Yamasaki Ikuko N Motoike Atsushi Hozawa Soichi Ogishima Naoko Minegishi Kozo Tanno Fumiki Katsuoka Gen Tamiya Setsuya Aiba Masayuki Yamamoto Kengo Kinoshita

The Journal of investigative dermatology 2021年4月

Possible Somatic Mosaicism of Novel FUS Variant in Familial Amyotrophic Lateral Sclerosis.

Shin Hisahara Ayumi Nishiyama Emiko Tsuda Syuuichirou Suzuki Akihiro Matsumura Aki Ishikawa Akihiro Sakurai Ikuko N Motoike Masashi Aoki Yoko Aoki Shun Shimohama

Neurology. Genetics 7(1) e552 2021年2月